One-Piece Zirconia Ceramic versus Titanium Implants in the Jaw and Femur of a Sheep Model: A Pilot Study
Identifieur interne : 006D35 ( Ncbi/Merge ); précédent : 006D34; suivant : 006D36One-Piece Zirconia Ceramic versus Titanium Implants in the Jaw and Femur of a Sheep Model: A Pilot Study
Auteurs : A. Siddiqi [Australie] ; W. J. Duncan [Nouvelle-Zélande] ; R. K. De Silva [Nouvelle-Zélande] ; S. Zafar [Australie]Source :
- BioMed Research International [ 2314-6133 ] ; 2016.
Abstract
Reports have documented titanium (Ti) hypersensitivity after dental implant treatment. Alternative materials have been suggested including zirconia (Zr) ceramics, which have shown predictable osseointegration in animal studies and appear free of immune responses. The aim of the research was to investigate the bone-to-implant contact (BIC) of one-piece Zr, compared with one-piece Ti implants, placed in the jaws and femurs of domestic sheep. Ten New Zealand mixed breed sheep were used. A One-piece prototype Ti (control) and one Zr (test) implant were placed in the mandible, and one of each implant (Ti and Zr) was placed into the femoral epicondyle of each animal. The femur implants were submerged and unloaded; the mandibular implants were placed using a one-stage transgingival protocol and were nonsubmerged. After a healing period of 12 weeks, %BIC was measured. The overall survival rate for mandibular and femur implants combined was 87.5%. %BIC was higher for Zr implants versus Ti implants in the femur (85.5%, versus 78.9%) (
Url:
DOI: 10.1155/2016/6792972
PubMed: 28058261
PubMed Central: 5183747
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Duncan</name><affiliation wicri:level="1"><nlm:aff id="I2">Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin, New Zealand</nlm:aff><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin</wicri:regionArea><wicri:noRegion>Dunedin</wicri:noRegion></affiliation></author><author><name sortKey="De Silva, R K" sort="De Silva, R K" uniqKey="De Silva R" first="R. K." last="De Silva">R. K. De Silva</name><affiliation wicri:level="1"><nlm:aff id="I2">Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin, New Zealand</nlm:aff><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin</wicri:regionArea><wicri:noRegion>Dunedin</wicri:noRegion></affiliation></author><author><name sortKey="Zafar, S" sort="Zafar, S" uniqKey="Zafar S" first="S." last="Zafar">S. Zafar</name><affiliation wicri:level="1"><nlm:aff id="I3">Discipline of Paediatric Dentistry, School of Oral Health, University of Western Australia, Perth, WA, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Discipline of Paediatric Dentistry, School of Oral Health, University of Western Australia, Perth, WA</wicri:regionArea><wicri:noRegion>WA</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">28058261</idno><idno type="pmc">5183747</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5183747</idno><idno type="RBID">PMC:5183747</idno><idno type="doi">10.1155/2016/6792972</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">002928</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002928</idno><idno type="wicri:Area/Pmc/Curation">002928</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002928</idno><idno type="wicri:Area/Pmc/Checkpoint">000566</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000566</idno><idno type="wicri:Area/Ncbi/Merge">006D35</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">One-Piece Zirconia Ceramic versus Titanium Implants in the Jaw and Femur of a Sheep Model: A Pilot Study</title><author><name sortKey="Siddiqi, A" sort="Siddiqi, A" uniqKey="Siddiqi A" first="A." last="Siddiqi">A. Siddiqi</name><affiliation wicri:level="1"><nlm:aff id="I1">School of Dentistry and Health Sciences, Charles Sturt University, Orange, NSW 2800, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Dentistry and Health Sciences, Charles Sturt University, Orange, NSW 2800</wicri:regionArea><wicri:noRegion>NSW 2800</wicri:noRegion></affiliation></author><author><name sortKey="Duncan, W J" sort="Duncan, W J" uniqKey="Duncan W" first="W. J." last="Duncan">W. J. Duncan</name><affiliation wicri:level="1"><nlm:aff id="I2">Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin, New Zealand</nlm:aff><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin</wicri:regionArea><wicri:noRegion>Dunedin</wicri:noRegion></affiliation></author><author><name sortKey="De Silva, R K" sort="De Silva, R K" uniqKey="De Silva R" first="R. K." last="De Silva">R. K. De Silva</name><affiliation wicri:level="1"><nlm:aff id="I2">Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin, New Zealand</nlm:aff><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin</wicri:regionArea><wicri:noRegion>Dunedin</wicri:noRegion></affiliation></author><author><name sortKey="Zafar, S" sort="Zafar, S" uniqKey="Zafar S" first="S." last="Zafar">S. Zafar</name><affiliation wicri:level="1"><nlm:aff id="I3">Discipline of Paediatric Dentistry, School of Oral Health, University of Western Australia, Perth, WA, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Discipline of Paediatric Dentistry, School of Oral Health, University of Western Australia, Perth, WA</wicri:regionArea><wicri:noRegion>WA</wicri:noRegion></affiliation></author></analytic><series><title level="j">BioMed Research International</title><idno type="ISSN">2314-6133</idno><idno type="eISSN">2314-6141</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Reports have documented titanium (Ti) hypersensitivity after dental implant treatment. Alternative materials have been suggested including zirconia (Zr) ceramics, which have shown predictable osseointegration in animal studies and appear free of immune responses. The aim of the research was to investigate the bone-to-implant contact (BIC) of one-piece Zr, compared with one-piece Ti implants, placed in the jaws and femurs of domestic sheep. Ten New Zealand mixed breed sheep were used. A One-piece prototype Ti (control) and one Zr (test) implant were placed in the mandible, and one of each implant (Ti and Zr) was placed into the femoral epicondyle of each animal. The femur implants were submerged and unloaded; the mandibular implants were placed using a one-stage transgingival protocol and were nonsubmerged. After a healing period of 12 weeks, %BIC was measured. The overall survival rate for mandibular and femur implants combined was 87.5%. %BIC was higher for Zr implants versus Ti implants in the femur (85.5%, versus 78.9%) (<italic>p</italic> = 0.002). Zirconia implants in the mandible showed comparable %BIC to titanium implants (72.2%, versus 60.3%) (<italic>p</italic> = 0.087). High failure rate of both Zr and Ti one-piece implants in the jaw could be attributed to the one-piece design and surface characteristics of the implant that could have influenced osseointegration. Further clinical trials are recommended to evaluate the performance of zirconia implants under loading conditions.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Kucey, B K S" uniqKey="Kucey B">B. K. S. Kucey</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schmalz, G" uniqKey="Schmalz G">G. Schmalz</name></author><author><name sortKey="Garhammer, P" uniqKey="Garhammer P">P. Garhammer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Siddiqi, A" uniqKey="Siddiqi A">A. Siddiqi</name></author><author><name sortKey="Payne, A G T" uniqKey="Payne A">A. G. T. Payne</name></author><author><name sortKey="De Silva, R K" uniqKey="De Silva R">R. K. De Silva</name></author><author><name sortKey="Duncan, W J" uniqKey="Duncan W">W. J. Duncan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Akagawa, Y" uniqKey="Akagawa Y">Y. Akagawa</name></author><author><name sortKey="Hosokawa, R" uniqKey="Hosokawa R">R. Hosokawa</name></author><author><name sortKey="Sato, Y" uniqKey="Sato Y">Y. Sato</name></author><author><name sortKey="Kamayama, K" uniqKey="Kamayama K">K. Kamayama</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sicilia, A" uniqKey="Sicilia A">A. Sicilia</name></author><author><name sortKey="Cuesta, S" uniqKey="Cuesta S">S. Cuesta</name></author><author><name sortKey="Coma, G" uniqKey="Coma G">G. Coma</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wenz, H J" uniqKey="Wenz H">H. J. Wenz</name></author><author><name sortKey="Bartsch, J" uniqKey="Bartsch J">J. Bartsch</name></author><author><name sortKey="Wolfart, S" uniqKey="Wolfart S">S. Wolfart</name></author><author><name sortKey="Kern, M" uniqKey="Kern M">M. Kern</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Preez, L A" uniqKey="Preez L">L. A. Preez</name></author><author><name sortKey="Butow, K W" uniqKey="Butow K">K. W. Bütow</name></author><author><name sortKey="Swart, T J" uniqKey="Swart T">T. J. Swart</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mine, Y" uniqKey="Mine Y">Y. Mine</name></author><author><name sortKey="Makihira, S" uniqKey="Makihira S">S. Makihira</name></author><author><name sortKey="Nikawa, H" uniqKey="Nikawa H">H. Nikawa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Olmedo, D G" uniqKey="Olmedo D">D. G. Olmedo</name></author><author><name sortKey="Paparella, M L" uniqKey="Paparella M">M. L. Paparella</name></author><author><name sortKey="Brandizzi, D" uniqKey="Brandizzi D">D. Brandizzi</name></author><author><name sortKey="Cabrini, R L" uniqKey="Cabrini R">R. L. Cabrini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Frisken, K W" uniqKey="Frisken K">K. W. Frisken</name></author><author><name sortKey="Dandie, G W" uniqKey="Dandie G">G. W. Dandie</name></author><author><name sortKey="Lugowski, S" uniqKey="Lugowski S">S. Lugowski</name></author><author><name sortKey="Jordan, G" uniqKey="Jordan G">G. Jordan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tawse Smith, A" uniqKey="Tawse Smith A">A. Tawse-Smith</name></author><author><name sortKey="Ma, S" uniqKey="Ma S">S. Ma</name></author><author><name sortKey="Siddiqi, A" uniqKey="Siddiqi A">A. Siddiqi</name></author><author><name sortKey="Duncan, W J" uniqKey="Duncan W">W. J. Duncan</name></author><author><name sortKey="Girvan, L" uniqKey="Girvan L">L. Girvan</name></author><author><name sortKey="Hussaini, H M" uniqKey="Hussaini H">H. M. Hussaini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Luckey, T D" uniqKey="Luckey T">T. D. Luckey</name></author><author><name sortKey="Veugapal, B" uniqKey="Veugapal B">B. Veugapal</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sakellariou, V I" uniqKey="Sakellariou V">V. I. Sakellariou</name></author><author><name sortKey="Atsali, E" uniqKey="Atsali E">E. Atsali</name></author><author><name sortKey="Starantzis, K" uniqKey="Starantzis K">K. Starantzis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hettige, S" uniqKey="Hettige S">S. Hettige</name></author><author><name sortKey="Norris, J S" uniqKey="Norris J">J. S. Norris</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Evrard, L" uniqKey="Evrard L">L. Evrard</name></author><author><name sortKey="Waroquier, D" uniqKey="Waroquier D">D. Waroquier</name></author><author><name sortKey="Parent, D" uniqKey="Parent D">D. Parent</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rimondini, L" uniqKey="Rimondini L">L. Rimondini</name></author><author><name sortKey="Cerroni, L" uniqKey="Cerroni L">L. Cerroni</name></author><author><name sortKey="Carrassi, A" uniqKey="Carrassi A">A. Carrassi</name></author><author><name sortKey="Torricelli, P" uniqKey="Torricelli P">P. Torricelli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Depprich, R" uniqKey="Depprich R">R. Depprich</name></author><author><name sortKey="Zipprich, H" uniqKey="Zipprich H">H. Zipprich</name></author><author><name sortKey="Ommerborn, M" uniqKey="Ommerborn M">M. Ommerborn</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Scarano, A" uniqKey="Scarano A">A. Scarano</name></author><author><name sortKey="Piattelli, M" uniqKey="Piattelli M">M. Piattelli</name></author><author><name sortKey="Vrespa, G" uniqKey="Vrespa G">G. Vrespa</name></author><author><name sortKey="Caputi, S" uniqKey="Caputi S">S. Caputi</name></author><author><name sortKey="Piattelli, A" uniqKey="Piattelli A">A. Piattelli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rocchietta, I" uniqKey="Rocchietta I">I. Rocchietta</name></author><author><name sortKey="Fontana, F" uniqKey="Fontana F">F. Fontana</name></author><author><name sortKey="Addis, A" uniqKey="Addis A">A. Addis</name></author><author><name sortKey="Schupbach, P" uniqKey="Schupbach P">P. Schupbach</name></author><author><name sortKey="Simion, M" uniqKey="Simion M">M. Simion</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kohal, R J" uniqKey="Kohal R">R. J. Kohal</name></author><author><name sortKey="Wolkewitz, M" uniqKey="Wolkewitz M">M. Wolkewitz</name></author><author><name sortKey="Hinze, M" uniqKey="Hinze M">M. Hinze</name></author><author><name sortKey="Han, J S" uniqKey="Han J">J.-S. Han</name></author><author><name sortKey="B Chle, M" uniqKey="B Chle M">M. Bächle</name></author><author><name sortKey="Butz, F" uniqKey="Butz F">F. Butz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Piconi, C" uniqKey="Piconi C">C. Piconi</name></author><author><name sortKey="Maccauro, G" uniqKey="Maccauro G">G. Maccauro</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pearce, A I" uniqKey="Pearce A">A. I. Pearce</name></author><author><name sortKey="Richards, R G" uniqKey="Richards R">R. G. Richards</name></author><author><name sortKey="Milz, S" uniqKey="Milz S">S. Milz</name></author><author><name sortKey="Schneider, E" uniqKey="Schneider E">E. Schneider</name></author><author><name sortKey="Pearce, S G" uniqKey="Pearce S">S. G. Pearce</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Newman, E" uniqKey="Newman E">E. Newman</name></author><author><name sortKey="Turner, A S" uniqKey="Turner A">A. S. Turner</name></author><author><name sortKey="Wark, J D" uniqKey="Wark J">J. D. Wark</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Duncan, W" uniqKey="Duncan W">W. Duncan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chappard, D" uniqKey="Chappard D">D. Chappard</name></author><author><name sortKey="Aguado, E" uniqKey="Aguado E">E. Aguado</name></author><author><name sortKey="Hure, G" uniqKey="Hure G">G. Huré</name></author><author><name sortKey="Grizon, F" uniqKey="Grizon F">F. Grizon</name></author><author><name sortKey="Basle, M F" uniqKey="Basle M">M. F. Basle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lucchini, J P" uniqKey="Lucchini J">J.-P. Lucchini</name></author><author><name sortKey="Aurelle, J L" uniqKey="Aurelle J">J.-L. Aurelle</name></author><author><name sortKey="Therin, M" uniqKey="Therin M">M. Therin</name></author><author><name sortKey="Donath, K" uniqKey="Donath K">K. Donath</name></author><author><name sortKey="Becker, W" uniqKey="Becker W">W. Becker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rohner, D" uniqKey="Rohner D">D. Rohner</name></author><author><name sortKey="Meng, C" uniqKey="Meng C">C. Meng</name></author><author><name sortKey="Hutmacher, D" uniqKey="Hutmacher D">D. Hutmacher</name></author><author><name sortKey="Tsai, K T" uniqKey="Tsai K">K. T. Tsai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Koch, F P" uniqKey="Koch F">F. P. Koch</name></author><author><name sortKey="Weng, D" uniqKey="Weng D">D. Weng</name></author><author><name sortKey="Kr Mer, S" uniqKey="Kr Mer S">S. Krämer</name></author><author><name sortKey="Biesterfeld, S" uniqKey="Biesterfeld S">S. Biesterfeld</name></author><author><name sortKey="Jahn Eimermacher, A" uniqKey="Jahn Eimermacher A">A. Jahn-Eimermacher</name></author><author><name sortKey="Wagner, W" uniqKey="Wagner W">W. Wagner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stadlinger, B" uniqKey="Stadlinger B">B. Stadlinger</name></author><author><name sortKey="Hennig, M" uniqKey="Hennig M">M. Hennig</name></author><author><name sortKey="Eckelt, U" uniqKey="Eckelt U">U. Eckelt</name></author><author><name sortKey="Kuhlisch, E" uniqKey="Kuhlisch E">E. Kuhlisch</name></author><author><name sortKey="Mai, R" uniqKey="Mai R">R. Mai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, B C" uniqKey="Lee B">B.-C. Lee</name></author><author><name sortKey="Yeo, I S" uniqKey="Yeo I">I.-S. Yeo</name></author><author><name sortKey="Kim, D J" uniqKey="Kim D">D.-J. Kim</name></author><author><name sortKey="Lee, J B" uniqKey="Lee J">J.-B. Lee</name></author><author><name sortKey="Kim, S H" uniqKey="Kim S">S.-H. Kim</name></author><author><name sortKey="Han, J S" uniqKey="Han J">J.-S. Han</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Poitout, D G" uniqKey="Poitout D">D. G. Poitout</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schlegel, K A" uniqKey="Schlegel K">K. A. Schlegel</name></author><author><name sortKey="Lutz, R" uniqKey="Lutz R">R. Lutz</name></author><author><name sortKey="Wehran, F" uniqKey="Wehran F">F. Wehran</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nunamaker, D M" uniqKey="Nunamaker D">D. M. Nunamaker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Roberts, W E" uniqKey="Roberts W">W. E. Roberts</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Campbell, D I" uniqKey="Campbell D">D. I. Campbell</name></author><author><name sortKey="Duncan, W J" uniqKey="Duncan W">W. J. Duncan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Duncan, W J" uniqKey="Duncan W">W. J. Duncan</name></author><author><name sortKey="Lee, M H" uniqKey="Lee M">M. H. Lee</name></author><author><name sortKey="Dovban, A S M" uniqKey="Dovban A">A. S. M. Dovban</name></author><author><name sortKey="Hendra, N" uniqKey="Hendra N">N. Hendra</name></author><author><name sortKey="Ershadi, S" uniqKey="Ershadi S">S. Ershadi</name></author><author><name sortKey="Rumende, H" uniqKey="Rumende H">H. Rumende</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Potes, J" uniqKey="Potes J">J. Potes</name></author><author><name sortKey="Costa Reis, J" uniqKey="Costa Reis J">J. Costa-Reis</name></author><author><name sortKey="Capela E Silva, F" uniqKey="Capela E Silva F">F. Capela e Silva</name></author><author><name sortKey="Relvas, C" uniqKey="Relvas C">C. Relvas</name></author><author><name sortKey="Cabrita, A S" uniqKey="Cabrita A">A. S. Cabrita</name></author><author><name sortKey="Sim Es, J A" uniqKey="Sim Es J">J. A. Simões</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nuss, K M R" uniqKey="Nuss K">K. M. R. Nuss</name></author><author><name sortKey="Auer, J A" uniqKey="Auer J">J. A. Auer</name></author><author><name sortKey="Boos, A" uniqKey="Boos A">A. Boos</name></author><author><name sortKey="Von Rechenberg, B" uniqKey="Von Rechenberg B">B. von Rechenberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kohal, R J" uniqKey="Kohal R">R. J. Kohal</name></author><author><name sortKey="Wolkewitz, M" uniqKey="Wolkewitz M">M. Wolkewitz</name></author><author><name sortKey="Tsakona, A" uniqKey="Tsakona A">A. Tsakona</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Depprich, R" uniqKey="Depprich R">R. Depprich</name></author><author><name sortKey="Naujoks, C" uniqKey="Naujoks C">C. Naujoks</name></author><author><name sortKey="Ommerborn, M" uniqKey="Ommerborn M">M. Ommerborn</name></author><author><name sortKey="Schwarz, F" uniqKey="Schwarz F">F. Schwarz</name></author><author><name sortKey="Kubler, N R" uniqKey="Kubler N">N. R. Kübler</name></author><author><name sortKey="Handschel, J" uniqKey="Handschel J">J. Handschel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Duda, M" uniqKey="Duda M">M. Duda</name></author><author><name sortKey="Matalon, S" uniqKey="Matalon S">S. Matalon</name></author><author><name sortKey="Lewinstein, I" uniqKey="Lewinstein I">I. Lewinstein</name></author><author><name sortKey="Harel, N" uniqKey="Harel N">N. Harel</name></author><author><name sortKey="Block, J" uniqKey="Block J">J. Block</name></author><author><name sortKey="Ormianer, Z" uniqKey="Ormianer Z">Z. Ormianer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ostman, P O" uniqKey="Ostman P">P.-O. Östman</name></author><author><name sortKey="Hellman, M" uniqKey="Hellman M">M. Hellman</name></author><author><name sortKey="Albrektsson, T" uniqKey="Albrektsson T">T. Albrektsson</name></author><author><name sortKey="Sennerby, L" uniqKey="Sennerby L">L. Sennerby</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hashim, D" uniqKey="Hashim D">D. Hashim</name></author><author><name sortKey="Cionca, N" uniqKey="Cionca N">N. Cionca</name></author><author><name sortKey="Courvoisier, D" uniqKey="Courvoisier D">D. Courvoisier</name></author><author><name sortKey="Mombelli, A" uniqKey="Mombelli A">A. Mombelli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chrcanovic, B R" uniqKey="Chrcanovic B">B. R. Chrcanovic</name></author><author><name sortKey="Albrektsson, T" uniqKey="Albrektsson T">T. Albrektsson</name></author><author><name sortKey="Wennerberg, A" uniqKey="Wennerberg A">A. Wennerberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jemat, A" uniqKey="Jemat A">A. Jemat</name></author><author><name sortKey="Ghazali, M J" uniqKey="Ghazali M">M. J. Ghazali</name></author><author><name sortKey="Razali, M" uniqKey="Razali M">M. Razali</name></author><author><name sortKey="Otsuka, Y" uniqKey="Otsuka Y">Y. Otsuka</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Smeets, R" uniqKey="Smeets R">R. Smeets</name></author><author><name sortKey="Stadlinger, B" uniqKey="Stadlinger B">B. Stadlinger</name></author><author><name sortKey="Schwarz, F" uniqKey="Schwarz F">F. Schwarz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jimbo, R" uniqKey="Jimbo R">R. Jimbo</name></author><author><name sortKey="Wennerberg, A" uniqKey="Wennerberg A">A. Wennerberg</name></author><author><name sortKey="Albrektsson, T" uniqKey="Albrektsson T">T. Albrektsson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Siddiqi, A" uniqKey="Siddiqi A">A. Siddiqi</name></author><author><name sortKey="Kieser, J A" uniqKey="Kieser J">J. A. Kieser</name></author><author><name sortKey="De Silva, R K" uniqKey="De Silva R">R. K. De Silva</name></author><author><name sortKey="Thomson, W M" uniqKey="Thomson W">W. M. Thomson</name></author><author><name sortKey="Duncan, W J" uniqKey="Duncan W">W. J. Duncan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Osman, R B" uniqKey="Osman R">R. B. Osman</name></author><author><name sortKey="Swain, M V" uniqKey="Swain M">M. V. Swain</name></author><author><name sortKey="Atieh, M" uniqKey="Atieh M">M. Atieh</name></author><author><name sortKey="Ma, S" uniqKey="Ma S">S. Ma</name></author><author><name sortKey="Duncan, W" uniqKey="Duncan W">W. Duncan</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Biomed Res Int</journal-id><journal-id journal-id-type="iso-abbrev">Biomed Res Int</journal-id><journal-id journal-id-type="publisher-id">BMRI</journal-id><journal-title-group><journal-title>BioMed Research International</journal-title></journal-title-group><issn pub-type="ppub">2314-6133</issn><issn pub-type="epub">2314-6141</issn><publisher><publisher-name>Hindawi Publishing Corporation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">28058261</article-id><article-id pub-id-type="pmc">5183747</article-id><article-id pub-id-type="doi">10.1155/2016/6792972</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title>One-Piece Zirconia Ceramic versus Titanium Implants in the Jaw and Femur of a Sheep Model: A Pilot Study</article-title></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid" authenticated="false">http://orcid.org/0000-0001-5528-9153</contrib-id><name><surname>Siddiqi</surname><given-names>A.</given-names></name><xref ref-type="aff" rid="I1"><sup>1</sup></xref><xref ref-type="corresp" rid="cor1"><sup>*</sup></xref></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid" authenticated="false">http://orcid.org/0000-0002-5412-0089</contrib-id><name><surname>Duncan</surname><given-names>W. J.</given-names></name><xref ref-type="aff" rid="I2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>De Silva</surname><given-names>R. K.</given-names></name><xref ref-type="aff" rid="I2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Zafar</surname><given-names>S.</given-names></name><xref ref-type="aff" rid="I3"><sup>3</sup></xref></contrib></contrib-group><aff id="I1"><sup>1</sup>School of Dentistry and Health Sciences, Charles Sturt University, Orange, NSW 2800, Australia</aff><aff id="I2"><sup>2</sup>Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin, New Zealand</aff><aff id="I3"><sup>3</sup>Discipline of Paediatric Dentistry, School of Oral Health, University of Western Australia, Perth, WA, Australia</aff><author-notes><corresp id="cor1">*A. Siddiqi: <email>asiddiqi@csu.edu.au</email></corresp><fn fn-type="other"><p>Academic Editor: Adriana Bigi</p></fn></author-notes><pub-date pub-type="ppub"><year>2016</year></pub-date><pub-date pub-type="epub"><day>12</day><month>12</month><year>2016</year></pub-date><volume>2016</volume><elocation-id>6792972</elocation-id><history><date date-type="received"><day>11</day><month>8</month><year>2016</year></date><date date-type="rev-recd"><day>17</day><month>10</month><year>2016</year></date><date date-type="accepted"><day>8</day><month>11</month><year>2016</year></date></history><permissions><copyright-statement>Copyright © 2016 A. Siddiqi et al.</copyright-statement><copyright-year>2016</copyright-year><license xlink:href="https://creativecommons.org/licenses/by/4.0/"><license-p>This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions><abstract><p>Reports have documented titanium (Ti) hypersensitivity after dental implant treatment. Alternative materials have been suggested including zirconia (Zr) ceramics, which have shown predictable osseointegration in animal studies and appear free of immune responses. The aim of the research was to investigate the bone-to-implant contact (BIC) of one-piece Zr, compared with one-piece Ti implants, placed in the jaws and femurs of domestic sheep. Ten New Zealand mixed breed sheep were used. A One-piece prototype Ti (control) and one Zr (test) implant were placed in the mandible, and one of each implant (Ti and Zr) was placed into the femoral epicondyle of each animal. The femur implants were submerged and unloaded; the mandibular implants were placed using a one-stage transgingival protocol and were nonsubmerged. After a healing period of 12 weeks, %BIC was measured. The overall survival rate for mandibular and femur implants combined was 87.5%. %BIC was higher for Zr implants versus Ti implants in the femur (85.5%, versus 78.9%) (<italic>p</italic> = 0.002). Zirconia implants in the mandible showed comparable %BIC to titanium implants (72.2%, versus 60.3%) (<italic>p</italic> = 0.087). High failure rate of both Zr and Ti one-piece implants in the jaw could be attributed to the one-piece design and surface characteristics of the implant that could have influenced osseointegration. Further clinical trials are recommended to evaluate the performance of zirconia implants under loading conditions.</p></abstract><funding-group><award-group><funding-source xlink:href="http://dx.doi.org/10.13039/501100001518">Maurice and Phyllis Paykel Trust</funding-source></award-group></funding-group></article-meta></front><floats-group><fig id="fig1" orientation="portrait" position="float"><label>Figure 1</label><caption><p>Prototype one-piece implants. (A) One-piece Ti implant. (B) One-piece Zr implant.</p></caption><graphic xlink:href="BMRI2016-6792972.001"></graphic></fig><fig id="fig2" orientation="portrait" position="float"><label>Figure 2</label><caption><p>Sheep jaw surgery. (A) Infiltration of the local anaesthetic solution. (B) Relieving incision on the alveolar crest for better access during extraction. (C) Full thickness-periosteal flap reflected for extraction. (D) Tooth extraction using elevator. (E) Closure of the wound with 3/0 vicryl. (F and G) One-piece Zr in the implant drill. (H) One-piece Ti and Zr implants in the jaw.</p></caption><graphic xlink:href="BMRI2016-6792972.002"></graphic></fig><fig id="fig3" orientation="portrait" position="float"><label>Figure 3</label><caption><p>Sheep femur surgery. (A) Incision and reflection of the overlying skin and subcutaneous tissues at the femur implant site. (B) Preparation of the implant site. (C–E) Surgical placement of a wide diameter zirconia and titanium implant. (F) Skin closure in layers after implant placement. The other three implants will be reported elsewhere.</p></caption><graphic xlink:href="BMRI2016-6792972.003"></graphic></fig><fig id="fig4" orientation="portrait" position="float"><label>Figure 4</label><caption><p>Measurement of bone-to-implant contact using NIH image analysis software, ImageJ®. Histological image of titanium implant in sheep femur (4x). Green line represents the total area of the implant. Red line represents the implant thread area not immediately in contact with the bone. So % BIC: green-red.</p></caption><graphic xlink:href="BMRI2016-6792972.004"></graphic></fig><fig id="fig5" orientation="portrait" position="float"><label>Figure 5</label><caption><p>Histology images of sheep jaw stained with MacNeal's tetrachrome at 12 weeks of healing. (a) Titanium implant at 2x. (b) Titanium implant at 4x. (c) Zirconia implant at 2x. (d) Zirconia implant at 4x. Old mineralized bone (OB). New bone (NB), unmineralized bone. Arrows represent the lining of osteoblast cells with osteogenic potential. Immediately following the deposition of osteoid, multinucleated osteoblasts commence the remodelling process and the formation of a Haversian system. Osteoid undergoes maturational changes that prepare them for the initial deposition of calcium phosphate crystals called mineralization front. Osteons (red asterisks) represent the structural end result of a focus of bone remodelling. Black asterisks represent hematopoietic and fatty marrow. Haversian canals (HC) enclose vascular structures, nerves, and lining cells. The development of primary and secondary osteons representing active bone formation and high BIC is visible in the figure. Scale bar: 100 <italic>μ</italic>m.</p></caption><graphic xlink:href="BMRI2016-6792972.005"></graphic></fig><fig id="fig6" orientation="portrait" position="float"><label>Figure 6</label><caption><p>Histology images of sheep femur under light microscope after 12 weeks of healing. (a) Titanium implant at 2x. (b) Titanium implant at 4x. (c) Zirconia implant at 2x. (d) Zirconia implant at 4x. Old bone (OB), mineralized. New bone (NB), unmineralized bone. Arrows represent the lining of osteoblast cells with osteogenic potential. Immediately following the deposition of osteoid, multinucleated osteoblasts commence the remodelling process and the formation of Haversian system. Osteons (red asterisks) represent the structural end result of a focus of bone remodelling. Black asterisks represent hematopoietic and fatty marrow. Haversian canals (HC) enclosing vascular structures, nerves, and lining cells. Dense bone with high BIC can be seen in (d). Scale bar: 100 <italic>μ</italic>m.</p></caption><graphic xlink:href="BMRI2016-6792972.006"></graphic></fig><table-wrap id="tab1" orientation="portrait" position="float"><label>Table 1</label><caption><p>Distribution of implants in the jaw and their outcomes.</p></caption><table frame="hsides" rules="groups"><thead><tr><th colspan="6" align="center" rowspan="1">Mandibular implants</th></tr><tr><th align="left" rowspan="1" colspan="1">Implant type</th><th align="center" rowspan="1" colspan="1">Placed</th><th align="center" rowspan="1" colspan="1">Integrated</th><th align="center" rowspan="1" colspan="1">Failing</th><th align="center" rowspan="1" colspan="1">Not integrated</th><th align="center" rowspan="1" colspan="1">Lost</th></tr></thead><tbody><tr><td align="left" rowspan="1" colspan="1">Zirconia</td><td align="center" rowspan="1" colspan="1">10</td><td align="center" rowspan="1" colspan="1">4</td><td align="center" rowspan="1" colspan="1">1</td><td align="center" rowspan="1" colspan="1">2</td><td align="center" rowspan="1" colspan="1">3</td></tr><tr><td align="left" rowspan="1" colspan="1">Titanium</td><td align="center" rowspan="1" colspan="1">10</td><td align="center" rowspan="1" colspan="1">7</td><td align="center" rowspan="1" colspan="1">3</td><td align="center" rowspan="1" colspan="1">0</td><td align="center" rowspan="1" colspan="1">0</td></tr></tbody></table><table-wrap-foot><fn><p>Wilcoxon signed ranks nonparametric comparison of nominal, nonnormal paired data. No stat sig difference, <italic>p</italic> = 0.18. Overall integration was 11/20 = 55%.</p></fn></table-wrap-foot></table-wrap><table-wrap id="tab2" orientation="portrait" position="float"><label>Table 2</label><caption><p>Percentage of bone-to-implant contact around titanium and zirconia implants.</p></caption><table frame="hsides" rules="groups"><thead><tr><th rowspan="2" align="left" colspan="1">% Bone implant contact</th><th colspan="2" align="center" rowspan="1">Femur</th><th colspan="2" align="center" rowspan="1">Mandible</th></tr><tr><th align="center" rowspan="1" colspan="1">Zirconia</th><th align="center" rowspan="1" colspan="1">Titanium</th><th align="center" rowspan="1" colspan="1">Zirconia</th><th align="center" rowspan="1" colspan="1">Titanium</th></tr></thead><tbody><tr><td align="left" rowspan="1" colspan="1">Minimum % BIC</td><td align="center" rowspan="1" colspan="1">31.4</td><td align="center" rowspan="1" colspan="1">18.6</td><td align="center" rowspan="1" colspan="1">12.2</td><td align="center" rowspan="1" colspan="1">10.6</td></tr><tr><td align="left" rowspan="1" colspan="1">Maximum % BIC</td><td align="center" rowspan="1" colspan="1">100</td><td align="center" rowspan="1" colspan="1">100</td><td align="center" rowspan="1" colspan="1">100</td><td align="center" rowspan="1" colspan="1">100</td></tr><tr><td align="left" rowspan="1" colspan="1">Mean<break></break>(±SD)</td><td align="center" rowspan="1" colspan="1">85.5<break></break>(±14.1)</td><td align="center" rowspan="1" colspan="1">79.0<break></break>(±18.5)</td><td align="center" rowspan="1" colspan="1">72.2<break></break>(±23.6)</td><td align="center" rowspan="1" colspan="1">60.2<break></break>(±22.4)</td></tr></tbody></table></table-wrap></floats-group></pmc><affiliations><list><country><li>Australie</li><li>Nouvelle-Zélande</li></country></list><tree><country name="Australie"><noRegion><name sortKey="Siddiqi, A" sort="Siddiqi, A" uniqKey="Siddiqi A" first="A." last="Siddiqi">A. Siddiqi</name></noRegion><name sortKey="Zafar, S" sort="Zafar, S" uniqKey="Zafar S" first="S." last="Zafar">S. Zafar</name></country><country name="Nouvelle-Zélande"><noRegion><name sortKey="Duncan, W J" sort="Duncan, W J" uniqKey="Duncan W" first="W. J." last="Duncan">W. J. Duncan</name></noRegion><name sortKey="De Silva, R K" sort="De Silva, R K" uniqKey="De Silva R" first="R. K." last="De Silva">R. K. De Silva</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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