Alveolar Ridge Reconstruction with Titanium Meshes and Simultaneous Implant Placement: A Retrospective, Multicenter Clinical Study
Identifieur interne : 006C97 ( Ncbi/Merge ); précédent : 006C96; suivant : 006C98Alveolar Ridge Reconstruction with Titanium Meshes and Simultaneous Implant Placement: A Retrospective, Multicenter Clinical Study
Auteurs : Raquel Zita Gomes [Portugal] ; Andres Paraud Freixas [Chili] ; Chang-Hun Han [Corée du Sud] ; Sohueil Bechara [Lituanie] ; Isaac Tawil [États-Unis]Source :
- BioMed Research International [ 2314-6133 ] ; 2016.
Abstract
Url:
DOI: 10.1155/2016/5126838
PubMed: 27999799
PubMed Central: 5141311
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PMC:5141311Le document en format XML
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<author><name sortKey="Zita Gomes, Raquel" sort="Zita Gomes, Raquel" uniqKey="Zita Gomes R" first="Raquel" last="Zita Gomes">Raquel Zita Gomes</name>
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<author><name sortKey="Han, Chang Hun" sort="Han, Chang Hun" uniqKey="Han C" first="Chang-Hun" last="Han">Chang-Hun Han</name>
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<author><name sortKey="Bechara, Sohueil" sort="Bechara, Sohueil" uniqKey="Bechara S" first="Sohueil" last="Bechara">Sohueil Bechara</name>
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<author><name sortKey="Tawil, Isaac" sort="Tawil, Isaac" uniqKey="Tawil I" first="Isaac" last="Tawil">Isaac Tawil</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Alveolar Ridge Reconstruction with Titanium Meshes and Simultaneous Implant Placement: A Retrospective, Multicenter Clinical Study</title>
<author><name sortKey="Zita Gomes, Raquel" sort="Zita Gomes, Raquel" uniqKey="Zita Gomes R" first="Raquel" last="Zita Gomes">Raquel Zita Gomes</name>
<affiliation wicri:level="1"><nlm:aff id="I1">Faculty of Dental Medicine, University of Oporto, Rua Manuel Pereira da Silva, 4200-393 Oporto, Portugal</nlm:aff>
<country xml:lang="fr">Portugal</country>
<wicri:regionArea>Faculty of Dental Medicine, University of Oporto, Rua Manuel Pereira da Silva, 4200-393 Oporto</wicri:regionArea>
<wicri:noRegion>4200-393 Oporto</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Paraud Freixas, Andres" sort="Paraud Freixas, Andres" uniqKey="Paraud Freixas A" first="Andres" last="Paraud Freixas">Andres Paraud Freixas</name>
<affiliation wicri:level="1"><nlm:aff id="I2">Private Practice, Gamero #504, 2840941 Rancagua, Chile</nlm:aff>
<country xml:lang="fr">Chili</country>
<wicri:regionArea>Private Practice, Gamero #504, 2840941 Rancagua</wicri:regionArea>
<wicri:noRegion>2840941 Rancagua</wicri:noRegion>
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<author><name sortKey="Han, Chang Hun" sort="Han, Chang Hun" uniqKey="Han C" first="Chang-Hun" last="Han">Chang-Hun Han</name>
<affiliation wicri:level="1"><nlm:aff id="I3">EasyPlant Dental Clinic, Seo-Gu, Gwangju 4455, Republic of Korea</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>EasyPlant Dental Clinic, Seo-Gu, Gwangju 4455</wicri:regionArea>
<wicri:noRegion>Gwangju 4455</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bechara, Sohueil" sort="Bechara, Sohueil" uniqKey="Bechara S" first="Sohueil" last="Bechara">Sohueil Bechara</name>
<affiliation wicri:level="1"><nlm:aff id="I4">Department of Oral and Maxillofacial Surgery, Lithuanian University of Health Science, LT-44307 Kaunas, Lithuania</nlm:aff>
<country xml:lang="fr">Lituanie</country>
<wicri:regionArea>Department of Oral and Maxillofacial Surgery, Lithuanian University of Health Science, LT-44307 Kaunas</wicri:regionArea>
<wicri:noRegion>LT-44307 Kaunas</wicri:noRegion>
</affiliation>
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<author><name sortKey="Tawil, Isaac" sort="Tawil, Isaac" uniqKey="Tawil I" first="Isaac" last="Tawil">Isaac Tawil</name>
<affiliation wicri:level="2"><nlm:aff id="I5">Private Practice, 345 Kings Highway, Brooklyn, NY 11223, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Private Practice, 345 Kings Highway, Brooklyn, NY 11223</wicri:regionArea>
<placeName><region type="state">État de New York</region>
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<series><title level="j">BioMed Research International</title>
<idno type="ISSN">2314-6133</idno>
<idno type="eISSN">2314-6141</idno>
<imprint><date when="2016">2016</date>
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<front><div type="abstract" xml:lang="en"><p><italic>Objective.</italic>
To evaluate horizontal bone gain and implant survival and complication rates in patients treated with titanium meshes placed simultaneously with dental implants and fixed over them.<italic> Methods.</italic>
Twenty-five patients treated with 40 implants and simultaneous guided bone regeneration with titanium meshes (i–Gen®, MegaGen, Gyeongbuk, Republic of Korea) were selected for inclusion in the present retrospective multicenter study. Primary outcomes were horizontal bone gain and implant survival; secondary outcomes were biological and prosthetic complications.<italic> Results.</italic>
After the removal of titanium meshes, the CBCT evaluation revealed a mean horizontal bone gain of 3.67 mm (±0.89). The most frequent complications were mild postoperative edema (12/25 patients: 48%) and discomfort after surgery (10/25 patients: 40%); these complications were resolved within one week. Titanium mesh exposure occurred in 6 patients (6/25 : 24%): one of these suffered partial loss of the graft and another experienced complete graft loss and implant failure. An implant survival rate of 97.5% (implant-based) and a peri-implant marginal bone loss of 0.43 mm (±0.15) were recorded after 1 year.<italic> Conclusions</italic>
. The horizontal ridge reconstruction with titanium meshes placed simultaneously with dental implants achieved predictable satisfactory results. Prospective randomized controlled trials on a larger sample of patients are required to validate these positive outcomes.</p>
</div>
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</TEI>
<pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Biomed Res Int</journal-id>
<journal-id journal-id-type="iso-abbrev">Biomed Res Int</journal-id>
<journal-id journal-id-type="publisher-id">BMRI</journal-id>
<journal-title-group><journal-title>BioMed Research International</journal-title>
</journal-title-group>
<issn pub-type="ppub">2314-6133</issn>
<issn pub-type="epub">2314-6141</issn>
<publisher><publisher-name>Hindawi Publishing Corporation</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">27999799</article-id>
<article-id pub-id-type="pmc">5141311</article-id>
<article-id pub-id-type="doi">10.1155/2016/5126838</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Clinical Study</subject>
</subj-group>
</article-categories>
<title-group><article-title>Alveolar Ridge Reconstruction with Titanium Meshes and Simultaneous Implant Placement: A Retrospective, Multicenter Clinical Study</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid" authenticated="false">http://orcid.org/0000-0002-3360-3903</contrib-id>
<name><surname>Zita Gomes</surname>
<given-names>Raquel</given-names>
</name>
<xref ref-type="aff" rid="I1"><sup>1</sup>
</xref>
<xref ref-type="corresp" rid="cor1"><sup>*</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Paraud Freixas</surname>
<given-names>Andres</given-names>
</name>
<xref ref-type="aff" rid="I2"><sup>2</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Han</surname>
<given-names>Chang-Hun</given-names>
</name>
<xref ref-type="aff" rid="I3"><sup>3</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Bechara</surname>
<given-names>Sohueil</given-names>
</name>
<xref ref-type="aff" rid="I4"><sup>4</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Tawil</surname>
<given-names>Isaac</given-names>
</name>
<xref ref-type="aff" rid="I5"><sup>5</sup>
</xref>
</contrib>
</contrib-group>
<aff id="I1"><sup>1</sup>
Faculty of Dental Medicine, University of Oporto, Rua Manuel Pereira da Silva, 4200-393 Oporto, Portugal</aff>
<aff id="I2"><sup>2</sup>
Private Practice, Gamero #504, 2840941 Rancagua, Chile</aff>
<aff id="I3"><sup>3</sup>
EasyPlant Dental Clinic, Seo-Gu, Gwangju 4455, Republic of Korea</aff>
<aff id="I4"><sup>4</sup>
Department of Oral and Maxillofacial Surgery, Lithuanian University of Health Science, LT-44307 Kaunas, Lithuania</aff>
<aff id="I5"><sup>5</sup>
Private Practice, 345 Kings Highway, Brooklyn, NY 11223, USA</aff>
<author-notes><corresp id="cor1">*Raquel Zita Gomes: <email>raquelzitagomes@hotmail.com</email>
</corresp>
<fn fn-type="other"><p>Academic Editor: Eitan Mijiritsky</p>
</fn>
</author-notes>
<pub-date pub-type="ppub"><year>2016</year>
</pub-date>
<pub-date pub-type="epub"><day>23</day>
<month>11</month>
<year>2016</year>
</pub-date>
<volume>2016</volume>
<elocation-id>5126838</elocation-id>
<history><date date-type="received"><day>30</day>
<month>9</month>
<year>2016</year>
</date>
<date date-type="accepted"><day>18</day>
<month>10</month>
<year>2016</year>
</date>
</history>
<permissions><copyright-statement>Copyright © 2016 Raquel Zita Gomes et al.</copyright-statement>
<copyright-year>2016</copyright-year>
<license xlink:href="https://creativecommons.org/licenses/by/4.0/"><license-p>This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<abstract><p><italic>Objective.</italic>
To evaluate horizontal bone gain and implant survival and complication rates in patients treated with titanium meshes placed simultaneously with dental implants and fixed over them.<italic> Methods.</italic>
Twenty-five patients treated with 40 implants and simultaneous guided bone regeneration with titanium meshes (i–Gen®, MegaGen, Gyeongbuk, Republic of Korea) were selected for inclusion in the present retrospective multicenter study. Primary outcomes were horizontal bone gain and implant survival; secondary outcomes were biological and prosthetic complications.<italic> Results.</italic>
After the removal of titanium meshes, the CBCT evaluation revealed a mean horizontal bone gain of 3.67 mm (±0.89). The most frequent complications were mild postoperative edema (12/25 patients: 48%) and discomfort after surgery (10/25 patients: 40%); these complications were resolved within one week. Titanium mesh exposure occurred in 6 patients (6/25 : 24%): one of these suffered partial loss of the graft and another experienced complete graft loss and implant failure. An implant survival rate of 97.5% (implant-based) and a peri-implant marginal bone loss of 0.43 mm (±0.15) were recorded after 1 year.<italic> Conclusions</italic>
. The horizontal ridge reconstruction with titanium meshes placed simultaneously with dental implants achieved predictable satisfactory results. Prospective randomized controlled trials on a larger sample of patients are required to validate these positive outcomes.</p>
</abstract>
</article-meta>
</front>
<floats-group><fig id="fig1" orientation="portrait" position="float"><label>Figure 1</label>
<caption><p>Presurgical clinical situation and elevation of full-thickness flap exposing the deficient alveolar ridge. (a) Preoperative clinical picture, frontal view; (b) preoperative clinical picture, occlusal view; (c) elevation of the mucoperiosteal flap, frontal view; (d) elevation of the mucoperiosteal flap, occlusal view.</p>
</caption>
<graphic xlink:href="BMRI2016-5126838.001"></graphic>
</fig>
<fig id="fig2" orientation="portrait" position="float"><label>Figure 2</label>
<caption><p>Preparation of the surgical sites and placement of the implants (AnyRidge, MegaGen, Gyeongbuk, Republic of Korea). (a) The implant sites have been prepared; (b) placement of the first implant in the position of the right lateral incisor; (c) placement of the second implant in the position of the left lateral incisor; (d) the implants<italic> in situ</italic>
.</p>
</caption>
<graphic xlink:href="BMRI2016-5126838.002"></graphic>
</fig>
<fig id="fig3" orientation="portrait" position="float"><label>Figure 3</label>
<caption><p>Details of the implant sites. (a) Details of the right implant site: fenestration of the thin buccal bone wall; (b) details of the left implant site: the buccal bone wall is thin and requires to be reinforced and protected.</p>
</caption>
<graphic xlink:href="BMRI2016-5126838.003"></graphic>
</fig>
<fig id="fig4" orientation="portrait" position="float"><label>Figure 4</label>
<caption><p>Placement of the titanium meshes (i–Gen, MegaGen, Gyeongbuk, Republic of Korea) and sutures. (a) The titanium meshes are connected to the implants and screwed on with the aid of a connecting screw; (b) particulate bone grafts are placed below the titanium mesh screwed on the right lateral incisor; (c) particulate bone grafts are placed below the titanium mesh screwed on the left lateral incisor; (d) sutures are performed.</p>
</caption>
<graphic xlink:href="BMRI2016-5126838.004"></graphic>
</fig>
<fig id="fig5" orientation="portrait" position="float"><label>Figure 5</label>
<caption><p>Second-stage surgery, removal of the titanium meshes and impressions. (a) and (b) Four months after placement, the titanium meshes were removed; (c) healing abutments were placed in position; (d) two weeks after placement of the healing abutments, impressions were taken.</p>
</caption>
<graphic xlink:href="BMRI2016-5126838.005"></graphic>
</fig>
<fig id="fig6" orientation="portrait" position="float"><label>Figure 6</label>
<caption><p>Cone beam computed tomography (CBCT) scans of the sites before surgery and after removal of the titanium meshes, three months later. (a) Right side: preoperative situation with a very thin residual alveolar ridge; (b) right side: the radiographic situation three months after surgery; (c) left side: preoperative situation with a thin residual alveolar ridge; (d) left side: the radiography three months after surgery.</p>
</caption>
<graphic xlink:href="BMRI2016-5126838.006"></graphic>
</fig>
<fig id="fig7" orientation="portrait" position="float"><label>Figure 7</label>
<caption><p>Prosthetic rehabilitations. (a) The provisional restoration<italic> in situ</italic>
, two weeks after the first impressions; (b) three months later, the precision of final structure is tested clinically; (c) the application of the definitive metal-ceramic FPP; (d) the final FPP at the final control.</p>
</caption>
<graphic xlink:href="BMRI2016-5126838.007"></graphic>
</fig>
<table-wrap id="tab1" orientation="portrait" position="float"><label>Table 1</label>
<caption><p>Patient-related information.</p>
</caption>
<table frame="hsides" rules="groups"><thead><tr><th align="left" rowspan="1" colspan="1"> </th>
<th align="center" rowspan="1" colspan="1">N° patients (%)</th>
<th align="center" rowspan="1" colspan="1"><italic>p</italic>
–value<sup><italic>∗</italic>
</sup>
</th>
</tr>
</thead>
<tbody><tr><td align="left" rowspan="1" colspan="1">Overall</td>
<td align="center" rowspan="1" colspan="1">25 (100%)</td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>Gender</italic>
</td>
<td align="center" rowspan="1" colspan="1"> </td>
<td align="center" rowspan="1" colspan="1"> </td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Males</td>
<td align="center" rowspan="1" colspan="1">15 (60%)</td>
<td rowspan="2" align="center" colspan="1">0.3173</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Females</td>
<td align="center" rowspan="1" colspan="1">10 (40%)</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>Age at surgery</italic>
</td>
<td align="center" rowspan="1" colspan="1"> </td>
<td align="center" rowspan="1" colspan="1"> </td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">43–51</td>
<td align="center" rowspan="1" colspan="1">11 (44%)</td>
<td rowspan="3" align="center" colspan="1">0.4677</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">52–60</td>
<td align="center" rowspan="1" colspan="1">8 (32%)</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">61–69</td>
<td align="center" rowspan="1" colspan="1">6 (24%)</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>Smoking habit</italic>
</td>
<td align="center" rowspan="1" colspan="1"> </td>
<td align="center" rowspan="1" colspan="1"> </td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Yes</td>
<td align="center" rowspan="1" colspan="1">8 (32%)</td>
<td rowspan="2" align="center" colspan="1">0.0719</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">No</td>
<td align="center" rowspan="1" colspan="1">17 (68%)</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>History of periodontal disease</italic>
</td>
<td align="center" rowspan="1" colspan="1"> </td>
<td align="center" rowspan="1" colspan="1"> </td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Yes</td>
<td align="center" rowspan="1" colspan="1">7 (28%)</td>
<td rowspan="2" align="center" colspan="1">0.0278</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">No</td>
<td align="center" rowspan="1" colspan="1">18 (72%)</td>
</tr>
</tbody>
</table>
<table-wrap-foot><fn><p><sup><italic>∗</italic>
</sup>
Chi-square test.</p>
</fn>
</table-wrap-foot>
</table-wrap>
<table-wrap id="tab2" orientation="portrait" position="float"><label>Table 2</label>
<caption><p>Implant-related information.</p>
</caption>
<table frame="hsides" rules="groups"><thead><tr><th align="left" rowspan="1" colspan="1"> </th>
<th align="center" rowspan="1" colspan="1">N° implants (%)</th>
<th align="center" rowspan="1" colspan="1"><italic>p</italic>
–value<sup><italic>∗</italic>
</sup>
</th>
</tr>
</thead>
<tbody><tr><td align="left" rowspan="1" colspan="1">Overall</td>
<td align="center" rowspan="1" colspan="1">40 (100%)</td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>Site</italic>
</td>
<td align="center" rowspan="1" colspan="1"> </td>
<td align="center" rowspan="1" colspan="1"> </td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Maxilla</td>
<td align="center" rowspan="1" colspan="1">32 (80%)</td>
<td rowspan="2" align="center" colspan="1">0.0001</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Mandible</td>
<td align="center" rowspan="1" colspan="1">8 (20%)</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>Position</italic>
</td>
<td align="center" rowspan="1" colspan="1"> </td>
<td align="center" rowspan="1" colspan="1"> </td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Incisor/cuspids</td>
<td align="center" rowspan="1" colspan="1">12 (30%)</td>
<td rowspan="3" align="center" colspan="1">0.0074</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Premolars</td>
<td align="center" rowspan="1" colspan="1">22 (55%)</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Molars</td>
<td align="center" rowspan="1" colspan="1">6 (15%)</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>Protocol</italic>
</td>
<td align="center" rowspan="1" colspan="1"> </td>
<td align="center" rowspan="1" colspan="1"> </td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Healed ridges</td>
<td align="center" rowspan="1" colspan="1">31 (77.5%)</td>
<td rowspan="2" align="center" colspan="1">0.0005</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Postextraction sockets</td>
<td align="center" rowspan="1" colspan="1">9 (22.5%)</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>Length</italic>
</td>
<td align="center" rowspan="1" colspan="1"> </td>
<td align="center" rowspan="1" colspan="1"> </td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">8.0 mm</td>
<td align="center" rowspan="1" colspan="1">7 (17.5%)</td>
<td rowspan="4" align="center" colspan="1">0.0203</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">10.0 mm</td>
<td align="center" rowspan="1" colspan="1">18 (45%)</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">11.5 mm</td>
<td align="center" rowspan="1" colspan="1">10 (25%)</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">13.0 mm</td>
<td align="center" rowspan="1" colspan="1">5 (12.5%)</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>Diameter</italic>
</td>
<td align="center" rowspan="1" colspan="1"> </td>
<td align="center" rowspan="1" colspan="1"> </td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">3.5 mm</td>
<td align="center" rowspan="1" colspan="1">19 (47.5%)</td>
<td rowspan="3" align="center" colspan="1">0.0655</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">4.0 mm</td>
<td align="center" rowspan="1" colspan="1">14 (35%)</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">4.5 mm</td>
<td align="center" rowspan="1" colspan="1">7 (17.5%)</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>Type</italic>
<italic>of</italic>
<italic>prosthesis</italic>
<sup><italic>∗∗</italic>
</sup>
</td>
<td align="center" rowspan="1" colspan="1"> </td>
<td align="center" rowspan="1" colspan="1"> </td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">SCs</td>
<td align="center" rowspan="1" colspan="1">17 (43.6%)</td>
<td rowspan="4" align="center" colspan="1">0.0225</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">FPPs (2 units)</td>
<td align="center" rowspan="1" colspan="1">12 (30.8%)</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">FPPs (3 units)</td>
<td align="center" rowspan="1" colspan="1">6 (15.4%)</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">FPPs (4 units)</td>
<td align="center" rowspan="1" colspan="1">4 (10.2%)</td>
</tr>
</tbody>
</table>
<table-wrap-foot><fn><p><sup><italic>∗</italic>
</sup>
Chi-square test test.</p>
</fn>
<fn><p><sup><italic>∗∗</italic>
</sup>
Calculated on the 39 surviving implants.</p>
</fn>
</table-wrap-foot>
</table-wrap>
<table-wrap id="tab3" orientation="portrait" position="float"><label>Table 3</label>
<caption><p>Peri-implant marginal bone loss between groups of implants at different time periods, in mm (implant level).</p>
</caption>
<table frame="hsides" rules="groups"><thead><tr><th align="left" rowspan="1" colspan="1"> </th>
<th align="center" rowspan="1" colspan="1">Baseline, 4 months</th>
<th align="center" rowspan="1" colspan="1">Baseline, 1 year</th>
</tr>
<tr><th align="left" rowspan="1" colspan="1"> </th>
<th align="left" rowspan="1" colspan="1"><italic>N</italic>
<sup><italic>∗</italic>
</sup>
; mean (SD); median; CI 95%</th>
<th align="left" rowspan="1" colspan="1"><italic>N</italic>
<sup><italic>∗</italic>
</sup>
; mean (SD); median; CI 95%</th>
</tr>
</thead>
<tbody><tr><td align="left" rowspan="1" colspan="1">Overall</td>
<td align="center" rowspan="1" colspan="1">39; 0.40 (±0.20); 0.35; 0.34–0.46</td>
<td align="center" rowspan="1" colspan="1">39; 0.43 (±0.15); 0.44; 0.39–0.47</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Healed sites</td>
<td align="center" rowspan="1" colspan="1">30; 0.42 (±0.21); 0.36; 0.35–0.49</td>
<td align="center" rowspan="1" colspan="1">30; 0.43 (±0.15); 0.44; 0.38–0.48</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Extraction sockets</td>
<td align="center" rowspan="1" colspan="1">9; 0.35 (±0.17); 0.34; 0.24–0.46</td>
<td align="center" rowspan="1" colspan="1">9; 0.41 (±0.17); 0.44; 0.30–0.52</td>
</tr>
</tbody>
</table>
<table-wrap-foot><fn><p><italic>N</italic>
<sup><italic>∗</italic>
</sup>
= number of the surviving implants.</p>
</fn>
</table-wrap-foot>
</table-wrap>
</floats-group>
</pmc>
<affiliations><list><country><li>Chili</li>
<li>Corée du Sud</li>
<li>Lituanie</li>
<li>Portugal</li>
<li>États-Unis</li>
</country>
<region><li>État de New York</li>
</region>
</list>
<tree><country name="Portugal"><noRegion><name sortKey="Zita Gomes, Raquel" sort="Zita Gomes, Raquel" uniqKey="Zita Gomes R" first="Raquel" last="Zita Gomes">Raquel Zita Gomes</name>
</noRegion>
</country>
<country name="Chili"><noRegion><name sortKey="Paraud Freixas, Andres" sort="Paraud Freixas, Andres" uniqKey="Paraud Freixas A" first="Andres" last="Paraud Freixas">Andres Paraud Freixas</name>
</noRegion>
</country>
<country name="Corée du Sud"><noRegion><name sortKey="Han, Chang Hun" sort="Han, Chang Hun" uniqKey="Han C" first="Chang-Hun" last="Han">Chang-Hun Han</name>
</noRegion>
</country>
<country name="Lituanie"><noRegion><name sortKey="Bechara, Sohueil" sort="Bechara, Sohueil" uniqKey="Bechara S" first="Sohueil" last="Bechara">Sohueil Bechara</name>
</noRegion>
</country>
<country name="États-Unis"><region name="État de New York"><name sortKey="Tawil, Isaac" sort="Tawil, Isaac" uniqKey="Tawil I" first="Isaac" last="Tawil">Isaac Tawil</name>
</region>
</country>
</tree>
</affiliations>
</record>
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