An open prospective single cohort multicenter study evaluating the novel, tapered, conical connection implants supporting single crowns in the anterior and premolar maxilla: interim 1-year results
Identifieur interne : 006C21 ( Ncbi/Merge ); précédent : 006C20; suivant : 006C22An open prospective single cohort multicenter study evaluating the novel, tapered, conical connection implants supporting single crowns in the anterior and premolar maxilla: interim 1-year results
Auteurs : Alexander Fügl [Autriche] ; Werner Zechner [Autriche] ; Alessandro Pozzi [Italie] ; Guido Heydecke [Allemagne] ; Christine Mirzakhanian [Allemagne] ; Nikolaus Behneke [Allemagne] ; Alexandra Behneke [Allemagne] ; Russell A. Baer [États-Unis] ; Robert Nölken [Allemagne] ; Edward Gottesman [États-Unis] ; Snjezana Colic [Serbie]Source :
- Clinical Oral Investigations [ 1432-6981 ] ; 2016.
Abstract
The aim of this multicenter prospective clinical study was to evaluate anodized tapered implants with a conical connection and integrated platform shifting placed in the anterior and premolar maxilla.
The study enrolled patients requiring single-tooth restorations in healed sites of maxillary anterior and premolar teeth. All implants were immediately temporized. Clinical and radiographic evaluations were conducted at implant insertion, 6 months, and 1 year. Outcome measures included bone remodeling, cumulative survival rate (CSR), success rate, soft-tissue health and esthetics, and patient satisfaction. Bone remodeling and pink esthetic score were analyzed using Wilcoxon signed-rank tests. CSR was calculated using life table analysis. Other soft-tissue outcomes were analyzed using sign tests.
Out of 97 enrolled patients (102 implants), 87 patients (91 implants) completed the 1-year visit. Marginal bone remodeling was −0.85 ± 1.36 mm. After the expected initial bone loss, a mean bone gain of 0.11 ± 1.05 mm was observed between 6 months and 1 year. The CSR was 99.0%, and the cumulative success rate was 97.0%. Partial or full papilla was observed at 30.8% of sites at baseline, 87.2% at 6 months, and 90.5% at 1 year. Soft-tissue response, esthetics, and patient satisfaction all improved during the study period.
Bone gain was observed following the expected initial bone loss, and soft-tissue outcomes improved suggesting favorable tissue response using anodized tapered conical connection implants.
Rapid stabilization of bone remodeling and robust papilla regeneration indicate favorable tissue healing promoted by the conical connection, platform-shift design.
Url:
DOI: 10.1007/s00784-016-2003-0
PubMed: 27864641
PubMed Central: 5487825
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<series><title level="j">Clinical Oral Investigations</title>
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<front><div type="abstract" xml:lang="en"><sec><title>Objectives</title>
<p id="Par1">The aim of this multicenter prospective clinical study was to evaluate anodized tapered implants with a conical connection and integrated platform shifting placed in the anterior and premolar maxilla.</p>
</sec>
<sec><title>Materials and methods</title>
<p id="Par2">The study enrolled patients requiring single-tooth restorations in healed sites of maxillary anterior and premolar teeth. All implants were immediately temporized. Clinical and radiographic evaluations were conducted at implant insertion, 6 months, and 1 year. Outcome measures included bone remodeling, cumulative survival rate (CSR), success rate, soft-tissue health and esthetics, and patient satisfaction. Bone remodeling and pink esthetic score were analyzed using Wilcoxon signed-rank tests. CSR was calculated using life table analysis. Other soft-tissue outcomes were analyzed using sign tests.</p>
</sec>
<sec><title>Results</title>
<p id="Par3">Out of 97 enrolled patients (102 implants), 87 patients (91 implants) completed the 1-year visit. Marginal bone remodeling was −0.85 ± 1.36 mm. After the expected initial bone loss, a mean bone gain of 0.11 ± 1.05 mm was observed between 6 months and 1 year. The CSR was 99.0%, and the cumulative success rate was 97.0%. Partial or full papilla was observed at 30.8% of sites at baseline, 87.2% at 6 months, and 90.5% at 1 year. Soft-tissue response, esthetics, and patient satisfaction all improved during the study period.</p>
</sec>
<sec><title>Conclusions</title>
<p id="Par4">Bone gain was observed following the expected initial bone loss, and soft-tissue outcomes improved suggesting favorable tissue response using anodized tapered conical connection implants.</p>
</sec>
<sec><title>Clinical relevance</title>
<p id="Par5">Rapid stabilization of bone remodeling and robust papilla regeneration indicate favorable tissue healing promoted by the conical connection, platform-shift design.</p>
</sec>
<sec><title>Trial registration</title>
<p id="Par6"><ext-link ext-link-type="uri" xlink:href="http://clinicaltrials.gov"><italic>clinicaltrials.gov</italic>
</ext-link>
NCT02175550</p>
</sec>
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<pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Clin Oral Investig</journal-id>
<journal-id journal-id-type="iso-abbrev">Clin Oral Investig</journal-id>
<journal-title-group><journal-title>Clinical Oral Investigations</journal-title>
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<issn pub-type="ppub">1432-6981</issn>
<issn pub-type="epub">1436-3771</issn>
<publisher><publisher-name>Springer Berlin Heidelberg</publisher-name>
<publisher-loc>Berlin/Heidelberg</publisher-loc>
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<article-meta><article-id pub-id-type="pmid">27864641</article-id>
<article-id pub-id-type="pmc">5487825</article-id>
<article-id pub-id-type="publisher-id">2003</article-id>
<article-id pub-id-type="doi">10.1007/s00784-016-2003-0</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject>
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<title-group><article-title>An open prospective single cohort multicenter study evaluating the novel, tapered, conical connection implants supporting single crowns in the anterior and premolar maxilla: interim 1-year results</article-title>
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<xref ref-type="aff" rid="Aff4">4</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Behneke</surname>
<given-names>Alexandra</given-names>
</name>
<xref ref-type="aff" rid="Aff4">4</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Baer</surname>
<given-names>Russell A.</given-names>
</name>
<xref ref-type="aff" rid="Aff5">5</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Nölken</surname>
<given-names>Robert</given-names>
</name>
<xref ref-type="aff" rid="Aff6">6</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Gottesman</surname>
<given-names>Edward</given-names>
</name>
<xref ref-type="aff" rid="Aff7">7</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Colic</surname>
<given-names>Snjezana</given-names>
</name>
<xref ref-type="aff" rid="Aff8">8</xref>
</contrib>
<aff id="Aff1"><label>1</label>
Bernhard Gottlieb University Clinic of Dentistry, Sensengasse 2a, 1090 Vienna, Austria</aff>
<aff id="Aff2"><label>2</label>
<institution-wrap><institution-id institution-id-type="ISNI">0000 0001 2300 0941</institution-id>
<institution-id institution-id-type="GRID">grid.6530.0</institution-id>
<institution></institution>
<institution>University of Rome Tor Vergata,</institution>
</institution-wrap>
Rome, Italy</aff>
<aff id="Aff3"><label>3</label>
<institution-wrap><institution-id institution-id-type="ISNI">0000 0001 2180 3484</institution-id>
<institution-id institution-id-type="GRID">grid.13648.38</institution-id>
<institution></institution>
<institution>University Medical Center Hamburg-Eppendorf,</institution>
</institution-wrap>
Hamburg, Germany</aff>
<aff id="Aff4"><label>4</label>
<institution-wrap><institution-id institution-id-type="GRID">grid.410607.4</institution-id>
<institution></institution>
<institution>University Medical Center of Johannes Gutenberg University Mainz,</institution>
</institution-wrap>
Mainz, Germany</aff>
<aff id="Aff5"><label>5</label>
University Associates in Dentistry, Chicago, USA</aff>
<aff id="Aff6"><label>6</label>
Private Practice, Lindau, Germany</aff>
<aff id="Aff7"><label>7</label>
Private Practice, New York, USA</aff>
<aff id="Aff8"><label>8</label>
<institution-wrap><institution-id institution-id-type="ISNI">0000 0001 2166 9385</institution-id>
<institution-id institution-id-type="GRID">grid.7149.b</institution-id>
<institution></institution>
<institution>University of Belgrade,</institution>
</institution-wrap>
Belgrade, Serbia</aff>
</contrib-group>
<pub-date pub-type="epub"><day>18</day>
<month>11</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>18</day>
<month>11</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="ppub"><year>2017</year>
</pub-date>
<volume>21</volume>
<issue>6</issue>
<fpage>2133</fpage>
<lpage>2142</lpage>
<history><date date-type="received"><day>9</day>
<month>5</month>
<year>2016</year>
</date>
<date date-type="accepted"><day>1</day>
<month>11</month>
<year>2016</year>
</date>
</history>
<permissions><copyright-statement>© The Author(s) 2016</copyright-statement>
<license license-type="OpenAccess"><license-p><bold>Open Access</bold>
This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.</license-p>
</license>
</permissions>
<abstract id="Abs1"><sec><title>Objectives</title>
<p id="Par1">The aim of this multicenter prospective clinical study was to evaluate anodized tapered implants with a conical connection and integrated platform shifting placed in the anterior and premolar maxilla.</p>
</sec>
<sec><title>Materials and methods</title>
<p id="Par2">The study enrolled patients requiring single-tooth restorations in healed sites of maxillary anterior and premolar teeth. All implants were immediately temporized. Clinical and radiographic evaluations were conducted at implant insertion, 6 months, and 1 year. Outcome measures included bone remodeling, cumulative survival rate (CSR), success rate, soft-tissue health and esthetics, and patient satisfaction. Bone remodeling and pink esthetic score were analyzed using Wilcoxon signed-rank tests. CSR was calculated using life table analysis. Other soft-tissue outcomes were analyzed using sign tests.</p>
</sec>
<sec><title>Results</title>
<p id="Par3">Out of 97 enrolled patients (102 implants), 87 patients (91 implants) completed the 1-year visit. Marginal bone remodeling was −0.85 ± 1.36 mm. After the expected initial bone loss, a mean bone gain of 0.11 ± 1.05 mm was observed between 6 months and 1 year. The CSR was 99.0%, and the cumulative success rate was 97.0%. Partial or full papilla was observed at 30.8% of sites at baseline, 87.2% at 6 months, and 90.5% at 1 year. Soft-tissue response, esthetics, and patient satisfaction all improved during the study period.</p>
</sec>
<sec><title>Conclusions</title>
<p id="Par4">Bone gain was observed following the expected initial bone loss, and soft-tissue outcomes improved suggesting favorable tissue response using anodized tapered conical connection implants.</p>
</sec>
<sec><title>Clinical relevance</title>
<p id="Par5">Rapid stabilization of bone remodeling and robust papilla regeneration indicate favorable tissue healing promoted by the conical connection, platform-shift design.</p>
</sec>
<sec><title>Trial registration</title>
<p id="Par6"><ext-link ext-link-type="uri" xlink:href="http://clinicaltrials.gov"><italic>clinicaltrials.gov</italic>
</ext-link>
NCT02175550</p>
</sec>
</abstract>
<kwd-group xml:lang="en"><title>Keywords</title>
<kwd>Conical connection</kwd>
<kwd>Platform shifting</kwd>
<kwd>Anterior maxilla</kwd>
<kwd>Immediate temporization</kwd>
</kwd-group>
<funding-group><award-group><funding-source><institution>Nobel Biocare Services AG</institution>
</funding-source>
<award-id>grant T-179</award-id>
</award-group>
</funding-group>
<custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name>
<meta-value>© Springer-Verlag GmbH Germany 2017</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
</front>
</pmc>
<affiliations><list><country><li>Allemagne</li>
<li>Autriche</li>
<li>Italie</li>
<li>Serbie</li>
<li>États-Unis</li>
</country>
<region><li>Illinois</li>
<li>Vienne (Autriche)</li>
<li>État de New York</li>
</region>
<settlement><li>Chicago</li>
<li>Vienne (Autriche)</li>
</settlement>
</list>
<tree><country name="Autriche"><region name="Vienne (Autriche)"><name sortKey="Fugl, Alexander" sort="Fugl, Alexander" uniqKey="Fugl A" first="Alexander" last="Fügl">Alexander Fügl</name>
</region>
<name sortKey="Zechner, Werner" sort="Zechner, Werner" uniqKey="Zechner W" first="Werner" last="Zechner">Werner Zechner</name>
</country>
<country name="Italie"><noRegion><name sortKey="Pozzi, Alessandro" sort="Pozzi, Alessandro" uniqKey="Pozzi A" first="Alessandro" last="Pozzi">Alessandro Pozzi</name>
</noRegion>
</country>
<country name="Allemagne"><noRegion><name sortKey="Heydecke, Guido" sort="Heydecke, Guido" uniqKey="Heydecke G" first="Guido" last="Heydecke">Guido Heydecke</name>
</noRegion>
<name sortKey="Behneke, Alexandra" sort="Behneke, Alexandra" uniqKey="Behneke A" first="Alexandra" last="Behneke">Alexandra Behneke</name>
<name sortKey="Behneke, Nikolaus" sort="Behneke, Nikolaus" uniqKey="Behneke N" first="Nikolaus" last="Behneke">Nikolaus Behneke</name>
<name sortKey="Mirzakhanian, Christine" sort="Mirzakhanian, Christine" uniqKey="Mirzakhanian C" first="Christine" last="Mirzakhanian">Christine Mirzakhanian</name>
<name sortKey="Nolken, Robert" sort="Nolken, Robert" uniqKey="Nolken R" first="Robert" last="Nölken">Robert Nölken</name>
</country>
<country name="États-Unis"><region name="Illinois"><name sortKey="Baer, Russell A" sort="Baer, Russell A" uniqKey="Baer R" first="Russell A." last="Baer">Russell A. Baer</name>
</region>
<name sortKey="Gottesman, Edward" sort="Gottesman, Edward" uniqKey="Gottesman E" first="Edward" last="Gottesman">Edward Gottesman</name>
</country>
<country name="Serbie"><noRegion><name sortKey="Colic, Snjezana" sort="Colic, Snjezana" uniqKey="Colic S" first="Snjezana" last="Colic">Snjezana Colic</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>
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