Can bone marrow aspirate concentrate change the mineralization pattern of the anterior maxilla treated with xenografts? A preliminary study
Identifieur interne : 006590 ( Ncbi/Merge ); précédent : 006589; suivant : 006591Can bone marrow aspirate concentrate change the mineralization pattern of the anterior maxilla treated with xenografts? A preliminary study
Auteurs : André Antonio Pelegrine ; Marcelo Lucchesi Teixeira ; Marcelo Sperandio ; Thiago Sousa Almada ; Karl Erik Kahnberg ; Paulo José Pasquali ; Antonio Carlos AloiseSource :
- Contemporary Clinical Dentistry [ 0976-237X ] ; 2016.
Abstract
To evaluate bony reconstruction of the atrophic anterior maxilla using particulate grafts with or without autologous bone marrow aspirate concentrate (BMAC).
Eight patients with atrophy of the anterior maxilla due to teeth loss were selected and split into groups according to the type of material used: Control Group (CG) (
Tomographic analysis revealed bone gain in CG of 3.78 ± 1.35 mm and 4.34 ± 1.58 mm at 4 and 8 months, respectively. TG showed an increase of 3.79 ± 0.52 mm and 4.09 ± 1.33 mm after 4 and 8 months, respectively. Histomorphometric analysis revealed that, for CG, MT- and NMT-related values were 52.3% ± 16.78% and 47.70% ± 5.55%, respectively, whereas for TG, they were 65.04% ± 20.98% and 34.96 ± 10.38, respectively.
Although radiographic bone gain appeared similar between the groups, the use of BMAC obtained via the BMAC® method revealed an increased mineralization trend in the anterior maxilla. It must be highlighted, however, that this is a preliminary study with a relatively small sample population and further studies with larger sample sizes are needed to verify these results.
Url:
DOI: 10.4103/0976-237X.177112
PubMed: 27041895
PubMed Central: 4792049
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000616
- to stream Pmc, to step Curation: 000616
- to stream Pmc, to step Checkpoint: 000850
Links to Exploration step
PMC:4792049Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Can bone marrow aspirate concentrate change the mineralization pattern of the anterior maxilla treated with xenografts? A preliminary study</title><author><name sortKey="Pelegrine, Andre Antonio" sort="Pelegrine, Andre Antonio" uniqKey="Pelegrine A" first="André Antonio" last="Pelegrine">André Antonio Pelegrine</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Teixeira, Marcelo Lucchesi" sort="Teixeira, Marcelo Lucchesi" uniqKey="Teixeira M" first="Marcelo Lucchesi" last="Teixeira">Marcelo Lucchesi Teixeira</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Sperandio, Marcelo" sort="Sperandio, Marcelo" uniqKey="Sperandio M" first="Marcelo" last="Sperandio">Marcelo Sperandio</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Almada, Thiago Sousa" sort="Almada, Thiago Sousa" uniqKey="Almada T" first="Thiago Sousa" last="Almada">Thiago Sousa Almada</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Kahnberg, Karl Erik" sort="Kahnberg, Karl Erik" uniqKey="Kahnberg K" first="Karl Erik" last="Kahnberg">Karl Erik Kahnberg</name><affiliation><nlm:aff id="aff2"><italic>Department of Oral Surgery, University of Gothenburg, Gothenburg, Sweden</italic></nlm:aff></affiliation></author><author><name sortKey="Pasquali, Paulo Jose" sort="Pasquali, Paulo Jose" uniqKey="Pasquali P" first="Paulo José" last="Pasquali">Paulo José Pasquali</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Aloise, Antonio Carlos" sort="Aloise, Antonio Carlos" uniqKey="Aloise A" first="Antonio Carlos" last="Aloise">Antonio Carlos Aloise</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27041895</idno><idno type="pmc">4792049</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792049</idno><idno type="RBID">PMC:4792049</idno><idno type="doi">10.4103/0976-237X.177112</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000616</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000616</idno><idno type="wicri:Area/Pmc/Curation">000616</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000616</idno><idno type="wicri:Area/Pmc/Checkpoint">000850</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000850</idno><idno type="wicri:Area/Ncbi/Merge">006590</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Can bone marrow aspirate concentrate change the mineralization pattern of the anterior maxilla treated with xenografts? A preliminary study</title><author><name sortKey="Pelegrine, Andre Antonio" sort="Pelegrine, Andre Antonio" uniqKey="Pelegrine A" first="André Antonio" last="Pelegrine">André Antonio Pelegrine</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Teixeira, Marcelo Lucchesi" sort="Teixeira, Marcelo Lucchesi" uniqKey="Teixeira M" first="Marcelo Lucchesi" last="Teixeira">Marcelo Lucchesi Teixeira</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Sperandio, Marcelo" sort="Sperandio, Marcelo" uniqKey="Sperandio M" first="Marcelo" last="Sperandio">Marcelo Sperandio</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Almada, Thiago Sousa" sort="Almada, Thiago Sousa" uniqKey="Almada T" first="Thiago Sousa" last="Almada">Thiago Sousa Almada</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Kahnberg, Karl Erik" sort="Kahnberg, Karl Erik" uniqKey="Kahnberg K" first="Karl Erik" last="Kahnberg">Karl Erik Kahnberg</name><affiliation><nlm:aff id="aff2"><italic>Department of Oral Surgery, University of Gothenburg, Gothenburg, Sweden</italic></nlm:aff></affiliation></author><author><name sortKey="Pasquali, Paulo Jose" sort="Pasquali, Paulo Jose" uniqKey="Pasquali P" first="Paulo José" last="Pasquali">Paulo José Pasquali</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Aloise, Antonio Carlos" sort="Aloise, Antonio Carlos" uniqKey="Aloise A" first="Antonio Carlos" last="Aloise">Antonio Carlos Aloise</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author></analytic><series><title level="j">Contemporary Clinical Dentistry</title><idno type="ISSN">0976-237X</idno><idno type="eISSN">0976-2361</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="st1"><title>Objective:</title><p>To evaluate bony reconstruction of the atrophic anterior maxilla using particulate grafts with or without autologous bone marrow aspirate concentrate (BMAC).</p></sec><sec id="st2"><title>Materials and Methods:</title><p>Eight patients with atrophy of the anterior maxilla due to teeth loss were selected and split into groups according to the type of material used: Control Group (CG) (<italic>n</italic> = 4) - particulate xenograft only and Test Group (TG) (<italic>n</italic> = 4) - a combination of particulate xenograft and BMAC. Both groups received a collagen membrane to cover the xenograft. After 4 months, during implant placement, a sample of bone was removed from the graft area using a 2 mm diameter trephine bur. The specimens were fixed and preserved for histomorphometric evaluation, which included the following parameters: Mineralized tissue (MT) and non-MT (NMT). Cone beam computed tomography was performed at 3 time intervals to measure bone thickness: (1) Before grafting, (2) 4 months and (3) 8 months postgrafting, using localized bone gain (mm) as the outcome variable.</p></sec><sec id="st3"><title>Results:</title><p>Tomographic analysis revealed bone gain in CG of 3.78 ± 1.35 mm and 4.34 ± 1.58 mm at 4 and 8 months, respectively. TG showed an increase of 3.79 ± 0.52 mm and 4.09 ± 1.33 mm after 4 and 8 months, respectively. Histomorphometric analysis revealed that, for CG, MT- and NMT-related values were 52.3% ± 16.78% and 47.70% ± 5.55%, respectively, whereas for TG, they were 65.04% ± 20.98% and 34.96 ± 10.38, respectively.</p></sec><sec id="st4"><title>Conclusion:</title><p>Although radiographic bone gain appeared similar between the groups, the use of BMAC obtained via the BMAC<sup>®</sup> method revealed an increased mineralization trend in the anterior maxilla. It must be highlighted, however, that this is a preliminary study with a relatively small sample population and further studies with larger sample sizes are needed to verify these results.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Pelegrine, Aa" uniqKey="Pelegrine A">AA Pelegrine</name></author><author><name sortKey="Da Costa, Ce" uniqKey="Da Costa C">CE da Costa</name></author><author><name sortKey="Correa, Me" uniqKey="Correa M">ME Correa</name></author><author><name sortKey="Marques, Jf" uniqKey="Marques J">JF Marques</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jensen, Ss" uniqKey="Jensen S">SS Jensen</name></author><author><name sortKey="Terheyden, H" uniqKey="Terheyden H">H Terheyden</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Esposito, M" uniqKey="Esposito M">M Esposito</name></author><author><name sortKey="Grusovin, Mg" uniqKey="Grusovin M">MG Grusovin</name></author><author><name sortKey="Felice, P" uniqKey="Felice P">P Felice</name></author><author><name sortKey="Karatzopoulos, G" uniqKey="Karatzopoulos G">G Karatzopoulos</name></author><author><name sortKey="Worthington, Hv" uniqKey="Worthington H">HV Worthington</name></author><author><name sortKey="Coulthard, P" uniqKey="Coulthard P">P Coulthard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Garaicoa Pazmi O, C" uniqKey="Garaicoa Pazmi O C">C Garaicoa-Pazmiño</name></author><author><name sortKey="Suarez L Pez Del Amo, F" uniqKey="Suarez L Pez Del Amo F">F Suárez-López del Amo</name></author><author><name sortKey="Monje, A" uniqKey="Monje A">A Monje</name></author><author><name sortKey="Catena, A" uniqKey="Catena A">A Catena</name></author><author><name sortKey="Ortega Oller, I" uniqKey="Ortega Oller I">I Ortega-Oller</name></author><author><name sortKey="Galindo Moreno, P" uniqKey="Galindo Moreno P">P Galindo-Moreno</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hernigou, P" uniqKey="Hernigou P">P Hernigou</name></author><author><name sortKey="Desroches, A" uniqKey="Desroches A">A Desroches</name></author><author><name sortKey="Queinnec, S" uniqKey="Queinnec S">S Queinnec</name></author><author><name sortKey="Flouzat Lachaniette, Ch" uniqKey="Flouzat Lachaniette C">CH Flouzat Lachaniette</name></author><author><name sortKey="Poignard, A" uniqKey="Poignard A">A Poignard</name></author><author><name sortKey="Allain, J" uniqKey="Allain J">J Allain</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pelegrine, Aa" uniqKey="Pelegrine A">AA Pelegrine</name></author><author><name sortKey="Aloise, Ac" uniqKey="Aloise A">AC Aloise</name></author><author><name sortKey="Zimmermann, A" uniqKey="Zimmermann A">A Zimmermann</name></author><author><name sortKey="De Mello E Oliveira, R" uniqKey="De Mello E Oliveira R">R de Mello E Oliveira</name></author><author><name sortKey="Ferreira, Lm" uniqKey="Ferreira L">LM Ferreira</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Mello E Oliveira, R" uniqKey="De Mello E Oliveira R">R de Mello e Oliveira</name></author><author><name sortKey="Pelegrine, Aa" uniqKey="Pelegrine A">AA Pelegrine</name></author><author><name sortKey="Aloise, Ac" uniqKey="Aloise A">AC Aloise</name></author><author><name sortKey="Ferreira, Lm" uniqKey="Ferreira L">LM Ferreira</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lekovic, V" uniqKey="Lekovic V">V Lekovic</name></author><author><name sortKey="Camargo, Pm" uniqKey="Camargo P">PM Camargo</name></author><author><name sortKey="Klokkevold, Pr" uniqKey="Klokkevold P">PR Klokkevold</name></author><author><name sortKey="Weinlaender, M" uniqKey="Weinlaender M">M Weinlaender</name></author><author><name sortKey="Kenney, Eb" uniqKey="Kenney E">EB Kenney</name></author><author><name sortKey="Dimitrijevic, B" uniqKey="Dimitrijevic B">B Dimitrijevic</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Donos, N" uniqKey="Donos N">N Donos</name></author><author><name sortKey="Kostopoulos, L" uniqKey="Kostopoulos L">L Kostopoulos</name></author><author><name sortKey="Tonetti, M" uniqKey="Tonetti M">M Tonetti</name></author><author><name sortKey="Karring, T" uniqKey="Karring T">T Karring</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nissan, J" uniqKey="Nissan J">J Nissan</name></author><author><name sortKey="Mardinger, O" uniqKey="Mardinger O">O Mardinger</name></author><author><name sortKey="Calderon, S" uniqKey="Calderon S">S Calderon</name></author><author><name sortKey="Romanos, Ge" uniqKey="Romanos G">GE Romanos</name></author><author><name sortKey="Chaushu, G" uniqKey="Chaushu G">G Chaushu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Da Costa, Ce" uniqKey="Da Costa C">CE da Costa</name></author><author><name sortKey="Pelegrine, Aa" uniqKey="Pelegrine A">AA Pelegrine</name></author><author><name sortKey="Fagundes, Dj" uniqKey="Fagundes D">DJ Fagundes</name></author><author><name sortKey="Simoes Mde, J" uniqKey="Simoes Mde J">J Simoes Mde</name></author><author><name sortKey="Taha, Mo" uniqKey="Taha M">MO Taha</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brugnami, F" uniqKey="Brugnami F">F Brugnami</name></author><author><name sortKey="Then, Pr" uniqKey="Then P">PR Then</name></author><author><name sortKey="Moroi, H" uniqKey="Moroi H">H Moroi</name></author><author><name sortKey="Kabani, S" uniqKey="Kabani S">S Kabani</name></author><author><name sortKey="Leone, Cw" uniqKey="Leone C">CW Leone</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Buser, D" uniqKey="Buser D">D Buser</name></author><author><name sortKey="Br Gger, U" uniqKey="Br Gger U">U Brägger</name></author><author><name sortKey="Lang, Np" uniqKey="Lang N">NP Lang</name></author><author><name sortKey="Nyman, S" uniqKey="Nyman S">S Nyman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Carpio, L" uniqKey="Carpio L">L Carpio</name></author><author><name sortKey="Loza, J" uniqKey="Loza J">J Loza</name></author><author><name sortKey="Lynch, S" uniqKey="Lynch S">S Lynch</name></author><author><name sortKey="Genco, R" uniqKey="Genco R">R Genco</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aloise, Ac" uniqKey="Aloise A">AC Aloise</name></author><author><name sortKey="Pelegrine, Aa" uniqKey="Pelegrine A">AA Pelegrine</name></author><author><name sortKey="Zimmermann, A" uniqKey="Zimmermann A">A Zimmermann</name></author><author><name sortKey="De Mello E Oliveira, R" uniqKey="De Mello E Oliveira R">R de Mello E Oliveira</name></author><author><name sortKey="Ferreira, Lm" uniqKey="Ferreira L">LM Ferreira</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hermann, Pc" uniqKey="Hermann P">PC Hermann</name></author><author><name sortKey="Huber, Sl" uniqKey="Huber S">SL Huber</name></author><author><name sortKey="Herrler, T" uniqKey="Herrler T">T Herrler</name></author><author><name sortKey="Von Hesler, C" uniqKey="Von Hesler C">C von Hesler</name></author><author><name sortKey="Andrassy, J" uniqKey="Andrassy J">J Andrassy</name></author><author><name sortKey="Kevy, Sv" uniqKey="Kevy S">SV Kevy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sauerbier, S" uniqKey="Sauerbier S">S Sauerbier</name></author><author><name sortKey="Stricker, A" uniqKey="Stricker A">A Stricker</name></author><author><name sortKey="Kuschnierz, J" uniqKey="Kuschnierz J">J Kuschnierz</name></author><author><name sortKey="Buhler, F" uniqKey="Buhler F">F Bühler</name></author><author><name sortKey="Oshima, T" uniqKey="Oshima T">T Oshima</name></author><author><name sortKey="Xavier, Sp" uniqKey="Xavier S">SP Xavier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rickert, D" uniqKey="Rickert D">D Rickert</name></author><author><name sortKey="Sauerbier, S" uniqKey="Sauerbier S">S Sauerbier</name></author><author><name sortKey="Nagursky, H" uniqKey="Nagursky H">H Nagursky</name></author><author><name sortKey="Menne, D" uniqKey="Menne D">D Menne</name></author><author><name sortKey="Vissink, A" uniqKey="Vissink A">A Vissink</name></author><author><name sortKey="Raghoebar, Gm" uniqKey="Raghoebar G">GM Raghoebar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sauerbier, S" uniqKey="Sauerbier S">S Sauerbier</name></author><author><name sortKey="Rickert, D" uniqKey="Rickert D">D Rickert</name></author><author><name sortKey="Gutwald, R" uniqKey="Gutwald R">R Gutwald</name></author><author><name sortKey="Nagursky, H" uniqKey="Nagursky H">H Nagursky</name></author><author><name sortKey="Oshima, T" uniqKey="Oshima T">T Oshima</name></author><author><name sortKey="Xavier, Sp" uniqKey="Xavier S">SP Xavier</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Contemp Clin Dent</journal-id><journal-id journal-id-type="iso-abbrev">Contemp Clin Dent</journal-id><journal-id journal-id-type="publisher-id">CCD</journal-id><journal-title-group><journal-title>Contemporary Clinical Dentistry</journal-title></journal-title-group><issn pub-type="ppub">0976-237X</issn><issn pub-type="epub">0976-2361</issn><publisher><publisher-name>Medknow Publications & Media Pvt Ltd</publisher-name><publisher-loc>India</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">27041895</article-id><article-id pub-id-type="pmc">4792049</article-id><article-id pub-id-type="publisher-id">CCD-7-21</article-id><article-id pub-id-type="doi">10.4103/0976-237X.177112</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject></subj-group></article-categories><title-group><article-title>Can bone marrow aspirate concentrate change the mineralization pattern of the anterior maxilla treated with xenografts? A preliminary study</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Pelegrine</surname><given-names>André Antonio</given-names></name><xref ref-type="aff" rid="aff1"></xref><xref ref-type="corresp" rid="cor1"></xref></contrib><contrib contrib-type="author"><name><surname>Teixeira</surname><given-names>Marcelo Lucchesi</given-names></name><xref ref-type="aff" rid="aff1"></xref></contrib><contrib contrib-type="author"><name><surname>Sperandio</surname><given-names>Marcelo</given-names></name><xref ref-type="aff" rid="aff1"></xref></contrib><contrib contrib-type="author"><name><surname>Almada</surname><given-names>Thiago Sousa</given-names></name><xref ref-type="aff" rid="aff1"></xref></contrib><contrib contrib-type="author"><name><surname>Kahnberg</surname><given-names>Karl Erik</given-names></name><xref ref-type="aff" rid="aff2">1</xref></contrib><contrib contrib-type="author"><name><surname>Pasquali</surname><given-names>Paulo José</given-names></name><xref ref-type="aff" rid="aff1"></xref></contrib><contrib contrib-type="author"><name><surname>Aloise</surname><given-names>Antonio Carlos</given-names></name><xref ref-type="aff" rid="aff1"></xref></contrib></contrib-group><aff id="aff1"><italic>Department of Implantology, São Leopoldo Mandic Institute and Research Center, Campinas, Brazil</italic></aff><aff id="aff2"><label>1</label><italic>Department of Oral Surgery, University of Gothenburg, Gothenburg, Sweden</italic></aff><author-notes><corresp id="cor1"><bold>Correspondence:</bold> Prof. André Antonio Pelegrine, Rua das Areias, 37, CEP 13024-530, São Paulo, Brazil. E-mail: <email xlink:href="pelegrineandre@gmail.com">pelegrineandre@gmail.com</email></corresp></author-notes><pub-date pub-type="ppub"><season>Jan-Mar</season><year>2016</year></pub-date><volume>7</volume><issue>1</issue><fpage>21</fpage><lpage>26</lpage><permissions><copyright-statement>Copyright: © Contemporary Clinical Dentistry</copyright-statement><copyright-year>2016</copyright-year><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc-sa/3.0"><license-p>This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.</license-p></license></permissions><abstract><sec id="st1"><title>Objective:</title><p>To evaluate bony reconstruction of the atrophic anterior maxilla using particulate grafts with or without autologous bone marrow aspirate concentrate (BMAC).</p></sec><sec id="st2"><title>Materials and Methods:</title><p>Eight patients with atrophy of the anterior maxilla due to teeth loss were selected and split into groups according to the type of material used: Control Group (CG) (<italic>n</italic> = 4) - particulate xenograft only and Test Group (TG) (<italic>n</italic> = 4) - a combination of particulate xenograft and BMAC. Both groups received a collagen membrane to cover the xenograft. After 4 months, during implant placement, a sample of bone was removed from the graft area using a 2 mm diameter trephine bur. The specimens were fixed and preserved for histomorphometric evaluation, which included the following parameters: Mineralized tissue (MT) and non-MT (NMT). Cone beam computed tomography was performed at 3 time intervals to measure bone thickness: (1) Before grafting, (2) 4 months and (3) 8 months postgrafting, using localized bone gain (mm) as the outcome variable.</p></sec><sec id="st3"><title>Results:</title><p>Tomographic analysis revealed bone gain in CG of 3.78 ± 1.35 mm and 4.34 ± 1.58 mm at 4 and 8 months, respectively. TG showed an increase of 3.79 ± 0.52 mm and 4.09 ± 1.33 mm after 4 and 8 months, respectively. Histomorphometric analysis revealed that, for CG, MT- and NMT-related values were 52.3% ± 16.78% and 47.70% ± 5.55%, respectively, whereas for TG, they were 65.04% ± 20.98% and 34.96 ± 10.38, respectively.</p></sec><sec id="st4"><title>Conclusion:</title><p>Although radiographic bone gain appeared similar between the groups, the use of BMAC obtained via the BMAC<sup>®</sup> method revealed an increased mineralization trend in the anterior maxilla. It must be highlighted, however, that this is a preliminary study with a relatively small sample population and further studies with larger sample sizes are needed to verify these results.</p></sec></abstract><kwd-group><kwd>Bone marrow</kwd><kwd>bone regeneration</kwd><kwd>stem cells</kwd></kwd-group></article-meta></front></pmc><affiliations><list></list><tree><noCountry><name sortKey="Almada, Thiago Sousa" sort="Almada, Thiago Sousa" uniqKey="Almada T" first="Thiago Sousa" last="Almada">Thiago Sousa Almada</name><name sortKey="Aloise, Antonio Carlos" sort="Aloise, Antonio Carlos" uniqKey="Aloise A" first="Antonio Carlos" last="Aloise">Antonio Carlos Aloise</name><name sortKey="Kahnberg, Karl Erik" sort="Kahnberg, Karl Erik" uniqKey="Kahnberg K" first="Karl Erik" last="Kahnberg">Karl Erik Kahnberg</name><name sortKey="Pasquali, Paulo Jose" sort="Pasquali, Paulo Jose" uniqKey="Pasquali P" first="Paulo José" last="Pasquali">Paulo José Pasquali</name><name sortKey="Pelegrine, Andre Antonio" sort="Pelegrine, Andre Antonio" uniqKey="Pelegrine A" first="André Antonio" last="Pelegrine">André Antonio Pelegrine</name><name sortKey="Sperandio, Marcelo" sort="Sperandio, Marcelo" uniqKey="Sperandio M" first="Marcelo" last="Sperandio">Marcelo Sperandio</name><name sortKey="Teixeira, Marcelo Lucchesi" sort="Teixeira, Marcelo Lucchesi" uniqKey="Teixeira M" first="Marcelo Lucchesi" last="Teixeira">Marcelo Lucchesi Teixeira</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Ncbi/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 006590 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd -nk 006590 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= EdenteV2
|flux= Ncbi
|étape= Merge
|type= RBID
|clé= PMC:4792049
|texte= Can bone marrow aspirate concentrate change the mineralization pattern of the anterior maxilla treated with xenografts? A preliminary study
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/RBID.i -Sk "pubmed:27041895" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd \
| NlmPubMed2Wicri -a EdenteV2
| This area was generated with Dilib version V0.6.32. |  |