Primary Diffuse Large B-Cell Lymphoma of the Mandible: Case Report and Review of the Literature
Identifieur interne : 006165 ( Ncbi/Merge ); précédent : 006164; suivant : 006166Primary Diffuse Large B-Cell Lymphoma of the Mandible: Case Report and Review of the Literature
Auteurs : Amr Bugshan [États-Unis] ; James Kassolis [États-Unis] ; John Basile [États-Unis]Source :
- Case Reports in Oncology [ 1662-6575 ] ; 2015.
Abstract
In the oral cavity, extranodal non-Hodgkin's lymphoma can occur in the periapical region either in the maxilla or mandible. Also, it can mimic inflammatory lesions that arise around the teeth apices such as periapical granuloma, radicular cyst and osteomyelitis. Misdiagnosis of lymphomas in the jaws may reduce the chance of successful treatment and worsen the prognosis. Therefore, any growth of periapical tissue must be submitted for histopathological evaluation to avoid a delay in the diagnosis. We present a case of extranodal non-Hodgkin's lymphoma of a 53-year-old male in the right posterior mandible that was initially misdiagnosed as a reactive periapical lesion. This case illustrates the importance for both the pathologist and the clinician of considering malignant lesions such as lymphoma in the differential diagnosis of periapical radiolucency.
Url:
DOI: 10.1159/000441469
PubMed: 26600778
PubMed Central: 4649735
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000123
- to stream Pmc, to step Curation: 000123
- to stream Pmc, to step Checkpoint: 000B40
Links to Exploration step
PMC:4649735Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Primary Diffuse Large B-Cell Lymphoma of the Mandible: Case Report and Review of the Literature</title><author><name sortKey="Bugshan, Amr" sort="Bugshan, Amr" uniqKey="Bugshan A" first="Amr" last="Bugshan">Amr Bugshan</name><affiliation wicri:level="4"><nlm:aff id="aff1">Department of Oncology and Diagnostic Sciences, Dental School, University of Maryland, Baltimore, Md., USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Oncology and Diagnostic Sciences, Dental School, University of Maryland, Baltimore, Md.</wicri:regionArea><orgName type="university">Université du Maryland</orgName><placeName><settlement type="city">College Park (Maryland)</settlement><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Kassolis, James" sort="Kassolis, James" uniqKey="Kassolis J" first="James" last="Kassolis">James Kassolis</name><affiliation wicri:level="1"><nlm:aff id="aff2">Towson Periodontal Associates, Towson, Md., USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Towson Periodontal Associates, Towson, Md.</wicri:regionArea><wicri:noRegion>Md.</wicri:noRegion></affiliation></author><author><name sortKey="Basile, John" sort="Basile, John" uniqKey="Basile J" first="John" last="Basile">John Basile</name><affiliation wicri:level="4"><nlm:aff id="aff1">Department of Oncology and Diagnostic Sciences, Dental School, University of Maryland, Baltimore, Md., USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Oncology and Diagnostic Sciences, Dental School, University of Maryland, Baltimore, Md.</wicri:regionArea><orgName type="university">Université du Maryland</orgName><placeName><settlement type="city">College Park (Maryland)</settlement><region type="state">Maryland</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26600778</idno><idno type="pmc">4649735</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649735</idno><idno type="RBID">PMC:4649735</idno><idno type="doi">10.1159/000441469</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">000123</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000123</idno><idno type="wicri:Area/Pmc/Curation">000123</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000123</idno><idno type="wicri:Area/Pmc/Checkpoint">000B40</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000B40</idno><idno type="wicri:Area/Ncbi/Merge">006165</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Primary Diffuse Large B-Cell Lymphoma of the Mandible: Case Report and Review of the Literature</title><author><name sortKey="Bugshan, Amr" sort="Bugshan, Amr" uniqKey="Bugshan A" first="Amr" last="Bugshan">Amr Bugshan</name><affiliation wicri:level="4"><nlm:aff id="aff1">Department of Oncology and Diagnostic Sciences, Dental School, University of Maryland, Baltimore, Md., USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Oncology and Diagnostic Sciences, Dental School, University of Maryland, Baltimore, Md.</wicri:regionArea><orgName type="university">Université du Maryland</orgName><placeName><settlement type="city">College Park (Maryland)</settlement><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Kassolis, James" sort="Kassolis, James" uniqKey="Kassolis J" first="James" last="Kassolis">James Kassolis</name><affiliation wicri:level="1"><nlm:aff id="aff2">Towson Periodontal Associates, Towson, Md., USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Towson Periodontal Associates, Towson, Md.</wicri:regionArea><wicri:noRegion>Md.</wicri:noRegion></affiliation></author><author><name sortKey="Basile, John" sort="Basile, John" uniqKey="Basile J" first="John" last="Basile">John Basile</name><affiliation wicri:level="4"><nlm:aff id="aff1">Department of Oncology and Diagnostic Sciences, Dental School, University of Maryland, Baltimore, Md., USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Oncology and Diagnostic Sciences, Dental School, University of Maryland, Baltimore, Md.</wicri:regionArea><orgName type="university">Université du Maryland</orgName><placeName><settlement type="city">College Park (Maryland)</settlement><region type="state">Maryland</region></placeName></affiliation></author></analytic><series><title level="j">Case Reports in Oncology</title><idno type="eISSN">1662-6575</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>In the oral cavity, extranodal non-Hodgkin's lymphoma can occur in the periapical region either in the maxilla or mandible. Also, it can mimic inflammatory lesions that arise around the teeth apices such as periapical granuloma, radicular cyst and osteomyelitis. Misdiagnosis of lymphomas in the jaws may reduce the chance of successful treatment and worsen the prognosis. Therefore, any growth of periapical tissue must be submitted for histopathological evaluation to avoid a delay in the diagnosis. We present a case of extranodal non-Hodgkin's lymphoma of a 53-year-old male in the right posterior mandible that was initially misdiagnosed as a reactive periapical lesion. This case illustrates the importance for both the pathologist and the clinician of considering malignant lesions such as lymphoma in the differential diagnosis of periapical radiolucency.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Neville, Bw" uniqKey="Neville B">BW Neville</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rooney, N" uniqKey="Rooney N">N Rooney</name></author><author><name sortKey="Ramsay, Ad" uniqKey="Ramsay A">AD Ramsay</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barnes, L" uniqKey="Barnes L">L Barnes</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Urquhart, A" uniqKey="Urquhart A">A Urquhart</name></author><author><name sortKey="Berg, R" uniqKey="Berg R">R Berg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guevara Canales, Jo" uniqKey="Guevara Canales J">JO Guevara-Canales</name></author><author><name sortKey="Morales Vadillo, R" uniqKey="Morales Vadillo R">R Morales-Vadillo</name></author><author><name sortKey="De Faria, Pe" uniqKey="De Faria P">PE de Faria</name></author><author><name sortKey="Sacsaquispe Contreras, Sj" uniqKey="Sacsaquispe Contreras S">SJ Sacsaquispe-Contreras</name></author><author><name sortKey="Leite, Fp" uniqKey="Leite F">FP Leite</name></author><author><name sortKey="Chaves, Mg" uniqKey="Chaves M">MG Chaves</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Epstein, Jb" uniqKey="Epstein J">JB Epstein</name></author><author><name sortKey="Epstein, Jd" uniqKey="Epstein J">JD Epstein</name></author><author><name sortKey="Le, Nd" uniqKey="Le N">ND Le</name></author><author><name sortKey="Gorsky, M" uniqKey="Gorsky M">M Gorsky</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shindoh, M" uniqKey="Shindoh M">M Shindoh</name></author><author><name sortKey="Takami, T" uniqKey="Takami T">T Takami</name></author><author><name sortKey="Arisue, M" uniqKey="Arisue M">M Arisue</name></author><author><name sortKey="Yamashita, T" uniqKey="Yamashita T">T Yamashita</name></author><author><name sortKey="Saito, T" uniqKey="Saito T">T Saito</name></author><author><name sortKey="Kohgo, T" uniqKey="Kohgo T">T Kohgo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Szumera Cieckiewicz, A" uniqKey="Szumera Cieckiewicz A">A Szumera-Cieckiewicz</name></author><author><name sortKey="Galazka, K" uniqKey="Galazka K">K Galazka</name></author><author><name sortKey="Szpor, J" uniqKey="Szpor J">J Szpor</name></author><author><name sortKey="Rymkiewicz, G" uniqKey="Rymkiewicz G">G Rymkiewicz</name></author><author><name sortKey="Jesionek Kupnicka, D" uniqKey="Jesionek Kupnicka D">D Jesionek-Kupnicka</name></author><author><name sortKey="Gruchala, A" uniqKey="Gruchala A">A Gruchala</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Etemad Moghadam, S" uniqKey="Etemad Moghadam S">S Etemad-Moghadam</name></author><author><name sortKey="Tirgary, F" uniqKey="Tirgary F">F Tirgary</name></author><author><name sortKey="Keshavarz, S" uniqKey="Keshavarz S">S Keshavarz</name></author><author><name sortKey="Alaeddini, M" uniqKey="Alaeddini M">M Alaeddini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Djavanmardi, L" uniqKey="Djavanmardi L">L Djavanmardi</name></author><author><name sortKey="Oprean, N" uniqKey="Oprean N">N Oprean</name></author><author><name sortKey="Alantar, A" uniqKey="Alantar A">A Alantar</name></author><author><name sortKey="Bousetta, K" uniqKey="Bousetta K">K Bousetta</name></author><author><name sortKey="Princ, G" uniqKey="Princ G">G Princ</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Regezi, Ja" uniqKey="Regezi J">JA Regezi</name></author><author><name sortKey="Sciubba, Jj" uniqKey="Sciubba J">JJ Sciubba</name></author><author><name sortKey="Jordan, Rck" uniqKey="Jordan R">RCK Jordan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mercadante, S" uniqKey="Mercadante S">S Mercadante</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="case-report"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Case Rep Oncol</journal-id><journal-id journal-id-type="iso-abbrev">Case Rep Oncol</journal-id><journal-id journal-id-type="publisher-id">CRO</journal-id><journal-title-group><journal-title>Case Reports in Oncology</journal-title></journal-title-group><issn pub-type="epub">1662-6575</issn><publisher><publisher-name>S. Karger AG</publisher-name><publisher-loc>Allschwilerstrasse 10, P.O. Box · Postfach · Case postale, CH–4009, Basel, Switzerland · Schweiz · Suisse, Phone: +41 61 306 11 11, Fax: +41 61 306 12 34, karger@karger.ch</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">26600778</article-id><article-id pub-id-type="pmc">4649735</article-id><article-id pub-id-type="doi">10.1159/000441469</article-id><article-id pub-id-type="publisher-id">cro-0008-0451</article-id><article-categories><subj-group subj-group-type="heading"><subject>Published online: October 2015</subject></subj-group></article-categories><title-group><article-title>Primary Diffuse Large B-Cell Lymphoma of the Mandible: Case Report and Review of the Literature</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Bugshan</surname><given-names>Amr</given-names></name><xref ref-type="aff" rid="aff1">a</xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><surname>Kassolis</surname><given-names>James</given-names></name><xref ref-type="aff" rid="aff2">b</xref></contrib><contrib contrib-type="author"><name><surname>Basile</surname><given-names>John</given-names></name><xref ref-type="aff" rid="aff1">a</xref></contrib></contrib-group><aff id="aff1"><sup>a</sup>Department of Oncology and Diagnostic Sciences, Dental School, University of Maryland, Baltimore, Md., USA</aff><aff id="aff2"><sup>b</sup>Towson Periodontal Associates, Towson, Md., USA</aff><author-notes><corresp id="cor1">*Dr. Amr Bugshan, Department of Oncology and Diagnostic Sciences, Dental School, University of Maryland, 650 West Baltimore Street, 7261, Baltimore, MD 21201-1586 (USA), E-Mail <email>abugshan@umaryland.edu</email></corresp></author-notes><pub-date pub-type="collection"><season>Sep-Dec</season><year>2015</year></pub-date><pub-date pub-type="epub"><day>24</day><month>10</month><year>2015</year></pub-date><pub-date pub-type="pmc-release"><day>24</day><month>10</month><year>2015</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on the
<volume>8</volume><issue>3</issue><fpage>451</fpage><lpage>455</lpage><permissions><copyright-statement>Copyright © 2015 by S. Karger AG, Basel</copyright-statement><copyright-year>2015</copyright-year><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc/4.0/"><license-p>This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.</license-p></license></permissions><abstract><p>In the oral cavity, extranodal non-Hodgkin's lymphoma can occur in the periapical region either in the maxilla or mandible. Also, it can mimic inflammatory lesions that arise around the teeth apices such as periapical granuloma, radicular cyst and osteomyelitis. Misdiagnosis of lymphomas in the jaws may reduce the chance of successful treatment and worsen the prognosis. Therefore, any growth of periapical tissue must be submitted for histopathological evaluation to avoid a delay in the diagnosis. We present a case of extranodal non-Hodgkin's lymphoma of a 53-year-old male in the right posterior mandible that was initially misdiagnosed as a reactive periapical lesion. This case illustrates the importance for both the pathologist and the clinician of considering malignant lesions such as lymphoma in the differential diagnosis of periapical radiolucency.</p></abstract><kwd-group><title>Key Words</title><kwd>Mandible</kwd><kwd>Non-Hodgkin's lymphoma</kwd><kwd>Periapical lesion</kwd><kwd>Oral cancer</kwd><kwd>Oral cavity</kwd><kwd>Swelling</kwd></kwd-group><counts><fig-count count="2"></fig-count><ref-count count="13"></ref-count><page-count count="5"></page-count></counts></article-meta></front><floats-group><fig id="F1" orientation="portrait" position="float"><label>Fig. 1</label><caption><p>Primary NHL of the mandible. <bold>a</bold> Periapical radiograph showing widening of the periodontal ligament and ill-defined radiolucency extending from tooth No. 30 to tooth No. 32. <bold>b</bold> Periapical radiograph showing bony destruction after extraction of teeth No. 30 and 32.</p></caption><graphic xlink:href="cro-0008-0451-g01"></graphic></fig><fig id="F2" orientation="portrait" position="float"><label>Fig. 2</label><caption><p>Right posterior mandible biopsy. <bold>a</bold> Photomicrograph showing multiple fragments of a squamous mucosa, soft tissue and bone with a dense lymphoid infiltrate (×10 magnification). <bold>b</bold> Photomicrograph showing an aggregate of atypical lymphoid cells (H&E staining; ×40 magnification). <bold>c</bold> Photomicrograph of immunohistochemical stain showing sheets of large mononuclear lymphoid cells positive for CD20 (×40 magnification). <bold>d</bold> Immunostaining for a CD10 showing a weak positivity (×40 magnification). <bold>e</bold>, <bold>f</bold> Scattered positivity is showing for CD3 and Bcl-6 immunostains (×40 magnification).</p></caption><graphic xlink:href="cro-0008-0451-g02"></graphic></fig></floats-group></pmc><affiliations><list><country><li>États-Unis</li></country><region><li>Maryland</li></region><settlement><li>College Park (Maryland)</li></settlement><orgName><li>Université du Maryland</li></orgName></list><tree><country name="États-Unis"><region name="Maryland"><name sortKey="Bugshan, Amr" sort="Bugshan, Amr" uniqKey="Bugshan A" first="Amr" last="Bugshan">Amr Bugshan</name></region><name sortKey="Basile, John" sort="Basile, John" uniqKey="Basile J" first="John" last="Basile">John Basile</name><name sortKey="Kassolis, James" sort="Kassolis, James" uniqKey="Kassolis J" first="James" last="Kassolis">James Kassolis</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Ncbi/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 006165 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd -nk 006165 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= EdenteV2
|flux= Ncbi
|étape= Merge
|type= RBID
|clé= PMC:4649735
|texte= Primary Diffuse Large B-Cell Lymphoma of the Mandible: Case Report and Review of the Literature
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/RBID.i -Sk "pubmed:26600778" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd \
| NlmPubMed2Wicri -a EdenteV2
| This area was generated with Dilib version V0.6.32. |  |