Validating cone-beam computed tomography for peri-implant bone morphometric analysis
Identifieur interne : 005E49 ( Ncbi/Merge ); précédent : 005E48; suivant : 005E50Validating cone-beam computed tomography for peri-implant bone morphometric analysis
Auteurs : Yan Huang [Belgique, République populaire de Chine] ; Jeroen Van Dessel [Belgique] ; Maarten Depypere [Belgique] ; Mostafa Ezeldeen [Belgique] ; Alexandru Andrei Iliescu [Roumanie] ; Emanuela Dos Santos [Brésil] ; Ivo Lambrichts [Belgique] ; Xin Liang [République populaire de Chine] ; Reinhilde Jacobs [Belgique]Source :
- Bone Research [ 2095-4700 ] ; 2014.
Abstract
Cone-beam computed tomography (CBCT) has been recently used to analyse trabecular bone structure around dental implants. To validate the use of CBCT for three-dimensional (3D) peri-implant trabecular bone morphometry by comparing it to two-dimensional (2D) histology, 36 alveolar bone samples (with implants
Url:
DOI: 10.1038/boneres.2014.10
PubMed: 26273522
PubMed Central: 4472132
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000816
- to stream Pmc, to step Curation: 000816
- to stream Pmc, to step Checkpoint: 001126
Links to Exploration step
PMC:4472132Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Validating cone-beam computed tomography for peri-implant bone morphometric analysis</title><author><name sortKey="Huang, Yan" sort="Huang, Yan" uniqKey="Huang Y" first="Yan" last="Huang">Yan Huang</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>OMFS IMPATH Research Group, Department of Imaging & Pathology, Faculty of Medicine, University of Leuven and Oral & Maxillofacial Surgery, University Hospitals Leuven</institution>, Leuven,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University</institution>, Chengdu,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Dessel, Jeroen Van" sort="Dessel, Jeroen Van" uniqKey="Dessel J" first="Jeroen Van" last="Dessel">Jeroen Van Dessel</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>OMFS IMPATH Research Group, Department of Imaging & Pathology, Faculty of Medicine, University of Leuven and Oral & Maxillofacial Surgery, University Hospitals Leuven</institution>, Leuven,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Depypere, Maarten" sort="Depypere, Maarten" uniqKey="Depypere M" first="Maarten" last="Depypere">Maarten Depypere</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>ESAT/PSI, Medical Image Computing, KU Leuven</institution>, Leuven,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Ezeldeen, Mostafa" sort="Ezeldeen, Mostafa" uniqKey="Ezeldeen M" first="Mostafa" last="Ezeldeen">Mostafa Ezeldeen</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>OMFS IMPATH Research Group, Department of Imaging & Pathology, Faculty of Medicine, University of Leuven and Oral & Maxillofacial Surgery, University Hospitals Leuven</institution>, Leuven,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Iliescu, Alexandru Andrei" sort="Iliescu, Alexandru Andrei" uniqKey="Iliescu A" first="Alexandru Andrei" last="Iliescu">Alexandru Andrei Iliescu</name><affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Faculty of Dentistry, UMF Craiova</institution>,<country>Romania</country></nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Santos, Emanuela Dos" sort="Santos, Emanuela Dos" uniqKey="Santos E" first="Emanuela Dos" last="Santos">Emanuela Dos Santos</name><affiliation wicri:level="1"><nlm:aff id="aff5"><institution>School of Dentistry, Pontifical Catholic University of Paraná</institution>, Curitiba,<country>Brazil</country></nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lambrichts, Ivo" sort="Lambrichts, Ivo" uniqKey="Lambrichts I" first="Ivo" last="Lambrichts">Ivo Lambrichts</name><affiliation wicri:level="1"><nlm:aff id="aff6"><institution>Biomedical Research Institute, Hasselt University</institution>, Diepenbeek,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Liang, Xin" sort="Liang, Xin" uniqKey="Liang X" first="Xin" last="Liang">Xin Liang</name><affiliation wicri:level="1"><nlm:aff id="aff7"><institution>School of Stomatology, Dalian Medical University</institution>, Dalian,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Jacobs, Reinhilde" sort="Jacobs, Reinhilde" uniqKey="Jacobs R" first="Reinhilde" last="Jacobs">Reinhilde Jacobs</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>OMFS IMPATH Research Group, Department of Imaging & Pathology, Faculty of Medicine, University of Leuven and Oral & Maxillofacial Surgery, University Hospitals Leuven</institution>, Leuven,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26273522</idno><idno type="pmc">4472132</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472132</idno><idno type="RBID">PMC:4472132</idno><idno type="doi">10.1038/boneres.2014.10</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">000816</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000816</idno><idno type="wicri:Area/Pmc/Curation">000816</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000816</idno><idno type="wicri:Area/Pmc/Checkpoint">001126</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001126</idno><idno type="wicri:Area/Ncbi/Merge">005E49</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Validating cone-beam computed tomography for peri-implant bone morphometric analysis</title><author><name sortKey="Huang, Yan" sort="Huang, Yan" uniqKey="Huang Y" first="Yan" last="Huang">Yan Huang</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>OMFS IMPATH Research Group, Department of Imaging & Pathology, Faculty of Medicine, University of Leuven and Oral & Maxillofacial Surgery, University Hospitals Leuven</institution>, Leuven,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University</institution>, Chengdu,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Dessel, Jeroen Van" sort="Dessel, Jeroen Van" uniqKey="Dessel J" first="Jeroen Van" last="Dessel">Jeroen Van Dessel</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>OMFS IMPATH Research Group, Department of Imaging & Pathology, Faculty of Medicine, University of Leuven and Oral & Maxillofacial Surgery, University Hospitals Leuven</institution>, Leuven,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Depypere, Maarten" sort="Depypere, Maarten" uniqKey="Depypere M" first="Maarten" last="Depypere">Maarten Depypere</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>ESAT/PSI, Medical Image Computing, KU Leuven</institution>, Leuven,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Ezeldeen, Mostafa" sort="Ezeldeen, Mostafa" uniqKey="Ezeldeen M" first="Mostafa" last="Ezeldeen">Mostafa Ezeldeen</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>OMFS IMPATH Research Group, Department of Imaging & Pathology, Faculty of Medicine, University of Leuven and Oral & Maxillofacial Surgery, University Hospitals Leuven</institution>, Leuven,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Iliescu, Alexandru Andrei" sort="Iliescu, Alexandru Andrei" uniqKey="Iliescu A" first="Alexandru Andrei" last="Iliescu">Alexandru Andrei Iliescu</name><affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Faculty of Dentistry, UMF Craiova</institution>,<country>Romania</country></nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Santos, Emanuela Dos" sort="Santos, Emanuela Dos" uniqKey="Santos E" first="Emanuela Dos" last="Santos">Emanuela Dos Santos</name><affiliation wicri:level="1"><nlm:aff id="aff5"><institution>School of Dentistry, Pontifical Catholic University of Paraná</institution>, Curitiba,<country>Brazil</country></nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lambrichts, Ivo" sort="Lambrichts, Ivo" uniqKey="Lambrichts I" first="Ivo" last="Lambrichts">Ivo Lambrichts</name><affiliation wicri:level="1"><nlm:aff id="aff6"><institution>Biomedical Research Institute, Hasselt University</institution>, Diepenbeek,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Liang, Xin" sort="Liang, Xin" uniqKey="Liang X" first="Xin" last="Liang">Xin Liang</name><affiliation wicri:level="1"><nlm:aff id="aff7"><institution>School of Stomatology, Dalian Medical University</institution>, Dalian,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Jacobs, Reinhilde" sort="Jacobs, Reinhilde" uniqKey="Jacobs R" first="Reinhilde" last="Jacobs">Reinhilde Jacobs</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>OMFS IMPATH Research Group, Department of Imaging & Pathology, Faculty of Medicine, University of Leuven and Oral & Maxillofacial Surgery, University Hospitals Leuven</institution>, Leuven,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Bone Research</title><idno type="ISSN">2095-4700</idno><idno type="eISSN">2095-6231</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Cone-beam computed tomography (CBCT) has been recently used to analyse trabecular bone structure around dental implants. To validate the use of CBCT for three-dimensional (3D) peri-implant trabecular bone morphometry by comparing it to two-dimensional (2D) histology, 36 alveolar bone samples (with implants <italic>n</italic>=27 <italic>vs.</italic> without implants <italic>n</italic>=9) from six mongrel dogs, were scanned <italic>ex vivo</italic> using a high-resolution (80 µm) CBCT. After scanning, all samples were decalcified and then sectioned into thin histological sections (∼6 μm) to obtain high contrast 2D images. By using CTAn imaging software, bone morphometric parameters including trabecular number (Tb.N), thickness (Tb.Th), separation (Tb.Sp) and bone volume fraction (BV/TV) were examined on both CBCT and corresponding histological images. Higher Tb.Th and Tb.Sp, lower BV/TV and Tb.N were found on CBCT images (<italic>P</italic><0.001). Both measurements on the peri-implant trabecular bone structure showed moderate to high correlation (<italic>r</italic>=0.65–0.85). The Bland–Altman plots showed strongest agreement for Tb.Th followed by Tb.Sp, Tb.N and BV/TV, regardless of the presence of implants. The current findings support the assumption that peri-implant trabecular bone structures based on high-resolution CBCT measurements are representative for the underlying histological bone characteristics, indicating a potential clinical diagnostic use of CBCT-based peri-implant bone morphometric characterisation.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Bone Res</journal-id><journal-id journal-id-type="iso-abbrev">Bone Res</journal-id><journal-title-group><journal-title>Bone Research</journal-title></journal-title-group><issn pub-type="ppub">2095-4700</issn><issn pub-type="epub">2095-6231</issn><publisher><publisher-name>Nature Publishing Group</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">26273522</article-id><article-id pub-id-type="pmc">4472132</article-id><article-id pub-id-type="pii">boneres201410</article-id><article-id pub-id-type="doi">10.1038/boneres.2014.10</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Validating cone-beam computed tomography for peri-implant bone morphometric analysis</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Huang</surname><given-names>Yan</given-names></name><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Dessel</surname><given-names>Jeroen Van</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Depypere</surname><given-names>Maarten</given-names></name><xref ref-type="aff" rid="aff3">3</xref></contrib><contrib contrib-type="author"><name><surname>EzEldeen</surname><given-names>Mostafa</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Iliescu</surname><given-names>Alexandru Andrei</given-names></name><xref ref-type="aff" rid="aff4">4</xref></contrib><contrib contrib-type="author"><name><surname>Santos</surname><given-names>Emanuela Dos</given-names></name><xref ref-type="aff" rid="aff5">5</xref></contrib><contrib contrib-type="author"><name><surname>Lambrichts</surname><given-names>Ivo</given-names></name><xref ref-type="aff" rid="aff6">6</xref></contrib><contrib contrib-type="author"><name><surname>Liang</surname><given-names>Xin</given-names></name><xref ref-type="aff" rid="aff7">7</xref></contrib><contrib contrib-type="author"><name><surname>Jacobs</surname><given-names>Reinhilde</given-names></name><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="corresp" rid="caf1">*</xref></contrib><aff id="aff1"><label>1</label><institution>OMFS IMPATH Research Group, Department of Imaging & Pathology, Faculty of Medicine, University of Leuven and Oral & Maxillofacial Surgery, University Hospitals Leuven</institution>, Leuven,<country>Belgium</country></aff><aff id="aff2"><label>2</label><institution>State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University</institution>, Chengdu,<country>China</country></aff><aff id="aff3"><label>3</label><institution>ESAT/PSI, Medical Image Computing, KU Leuven</institution>, Leuven,<country>Belgium</country></aff><aff id="aff4"><label>4</label><institution>Faculty of Dentistry, UMF Craiova</institution>,<country>Romania</country></aff><aff id="aff5"><label>5</label><institution>School of Dentistry, Pontifical Catholic University of Paraná</institution>, Curitiba,<country>Brazil</country></aff><aff id="aff6"><label>6</label><institution>Biomedical Research Institute, Hasselt University</institution>, Diepenbeek,<country>Belgium</country></aff><aff id="aff7"><label>7</label><institution>School of Stomatology, Dalian Medical University</institution>, Dalian,<country>China</country></aff></contrib-group><author-notes><corresp id="caf1"><label>*</label><email>reinhilde.jacobs@med.kuleuven.be</email></corresp></author-notes><pub-date pub-type="epub"><day>10</day><month>06</month><year>2014</year></pub-date><pub-date pub-type="collection"><year>2014</year></pub-date><volume>2</volume><fpage>14010</fpage><lpage></lpage><history><date date-type="received"><day>15</day><month>02</month><year>2014</year></date><date date-type="rev-recd"><day>05</day><month>04</month><year>2014</year></date><date date-type="accepted"><day>21</day><month>04</month><year>2014</year></date></history><permissions><copyright-statement>Copyright © 2014 Sichuan University</copyright-statement><copyright-year>2014</copyright-year><copyright-holder>Sichuan University</copyright-holder><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc-nd/3.0/"><pmc-comment>author-paid</pmc-comment>
<license-p>This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit <ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by-nc-nd/3.0/">http://creativecommons.org/licenses/by-nc-nd/3.0/</ext-link></license-p></license></permissions><abstract><p>Cone-beam computed tomography (CBCT) has been recently used to analyse trabecular bone structure around dental implants. To validate the use of CBCT for three-dimensional (3D) peri-implant trabecular bone morphometry by comparing it to two-dimensional (2D) histology, 36 alveolar bone samples (with implants <italic>n</italic>=27 <italic>vs.</italic> without implants <italic>n</italic>=9) from six mongrel dogs, were scanned <italic>ex vivo</italic> using a high-resolution (80 µm) CBCT. After scanning, all samples were decalcified and then sectioned into thin histological sections (∼6 μm) to obtain high contrast 2D images. By using CTAn imaging software, bone morphometric parameters including trabecular number (Tb.N), thickness (Tb.Th), separation (Tb.Sp) and bone volume fraction (BV/TV) were examined on both CBCT and corresponding histological images. Higher Tb.Th and Tb.Sp, lower BV/TV and Tb.N were found on CBCT images (<italic>P</italic><0.001). Both measurements on the peri-implant trabecular bone structure showed moderate to high correlation (<italic>r</italic>=0.65–0.85). The Bland–Altman plots showed strongest agreement for Tb.Th followed by Tb.Sp, Tb.N and BV/TV, regardless of the presence of implants. The current findings support the assumption that peri-implant trabecular bone structures based on high-resolution CBCT measurements are representative for the underlying histological bone characteristics, indicating a potential clinical diagnostic use of CBCT-based peri-implant bone morphometric characterisation.</p></abstract></article-meta></front><floats-group><fig id="fig1"><label>Figure 1</label><caption><p>(<bold>a</bold>) Three-dimensional models reconstructed from cone-beam computed tomography images in the coronal plane (mesial–distal view). (<bold>b</bold>) Three VOIs (coronal, middle and apical levels) were automatically selected from (<bold>a</bold>) along the surface of implant by a custom processing algorithm based on thresholding segmentation. (<bold>c</bold>) Histological slice of bone specimens (trichrome Masson stain; magnification, ×5) showed the trabecular bone (blue) and bone marrow (pink). (<bold>d</bold>) Trabecular bone in the binarized histological image at three manually selected ROIs. (<bold>e</bold>) Similar regions of interest were visually located in the 3D volume (80 μm resolution), corresponding to those in the 2D images (<bold>d</bold>) with a resolution of 6 μm.</p></caption><graphic xlink:href="boneres201410-f1"></graphic></fig><fig id="fig2"><label>Figure 2</label><caption><p>Bland–Altman plot comparing the agreement between cone-beam CT (CBCT) and histology in the bone samples with implant (<bold>a</bold>, <bold>c</bold>, <bold>e</bold>, <bold>g</bold>) and without implant (<bold>b</bold>, <bold>d</bold>, <bold>f</bold>, <bold>h</bold>) for the following bone structural parameters measurements: bone volume fraction (BV/TV), bone thickness (Tb.Th), bone separation (Tb.Sp) and trabecular number (Tb.N). Positive values represented larger BV/TV and Tb.N obtained from histological data compared with CBCT (<bold>a</bold>, <bold>b</bold>, <bold>g</bold>, <bold>h</bold>), while negative values showed smaller Tb.Th and Tb.Sp calculated from histology when comparing CBCT (<bold>c</bold>–<bold>f</bold>). The dotted lines on the Bland–Altman plot indicated the mean difference±1.96 standard deviations.</p></caption><graphic xlink:href="boneres201410-f2"></graphic></fig><table-wrap id="tbl1"><label>Table 1</label><caption><title>Distribution of alveolar bone samples in six experimental dogs</title></caption><table frame="hsides" rules="groups" border="1"><colgroup><col align="left"></col><col align="left"></col><col align="left"></col><col align="left"></col><col align="left"></col><col align="left"></col><col align="left"></col><col align="left"></col></colgroup><tbody valign="top"><tr><td align="left" valign="top" charoff="50">Group</td><td align="left" valign="top" charoff="50">I (R)</td><td align="left" valign="top" charoff="50">I (L)</td><td align="left" valign="top" charoff="50">P3 (R)</td><td align="left" valign="top" charoff="50">P3 (L)</td><td align="left" valign="top" charoff="50">P4 (R)</td><td align="left" valign="top" charoff="50">P4 (L)</td><td align="left" valign="top" charoff="50">Total</td></tr><tr><td align="left" valign="top" charoff="50">Bone with implants</td><td align="left" valign="top" charoff="50">4</td><td align="left" valign="top" charoff="50">5</td><td align="left" valign="top" charoff="50">5</td><td align="left" valign="top" charoff="50">5</td><td align="left" valign="top" charoff="50">4</td><td align="left" valign="top" charoff="50">4</td><td align="left" valign="top" charoff="50">27</td></tr><tr><td align="left" valign="top" charoff="50">Bone without implants</td><td align="left" valign="top" charoff="50">2</td><td align="left" valign="top" charoff="50">1</td><td align="left" valign="top" charoff="50">1</td><td align="left" valign="top" charoff="50">1</td><td align="left" valign="top" charoff="50">2</td><td align="left" valign="top" charoff="50">2</td><td align="left" valign="top" charoff="50">9</td></tr></tbody></table><table-wrap-foot><fn id="t1-tfoot1"><p>I, third maxillary incisors; P3, third mandibular premolars; P4, fourth mandibular premolars; R, right side; L, left side; implants, custom-made threaded, grade 5 pure titanium, machined surface, Ø=3.1 mm for I and 4.1 mm for P3 and P4, length=11 mm.</p></fn></table-wrap-foot></table-wrap><table-wrap id="tbl2"><label>Table 2</label><caption><title>Trabecular morphological parameters quantified from CBCT and histological images in selected regions of interest and volumes of interest, based on the parallel plate model</title></caption><table frame="hsides" rules="groups" border="1"><colgroup><col align="left"></col><col align="left"></col><col align="left"></col><col align="left"></col><col align="left"></col></colgroup><tbody valign="top"><tr><td align="left" valign="top" charoff="50">Morphological parameter</td><td align="left" valign="top" charoff="50">Abbreviation</td><td align="left" valign="top" charoff="50">Unit</td><td align="left" valign="top" charoff="50">2D measurements</td><td align="left" valign="top" charoff="50">3D measurements</td></tr><tr><td align="left" valign="top" charoff="50">Bone volume fraction</td><td align="left" valign="top" charoff="50">BV/TV</td><td align="left" valign="top" charoff="50">%</td><td align="left" valign="top" charoff="50">(A<sub>B</sub>/A<sub>T</sub>)100</td><td align="left" valign="top" charoff="50">BV/TV</td></tr><tr><td align="left" valign="top" charoff="50">Trabecular thickness</td><td align="left" valign="top" charoff="50">Tb.Th</td><td align="left" valign="top" charoff="50">mm</td><td align="left" valign="top" charoff="50">(2/1.199)(A<sub>B</sub>/P<sub>B</sub>)</td><td align="left" valign="top" charoff="50">2BV/BS</td></tr><tr><td align="left" valign="top" charoff="50">Trabecular separation</td><td align="left" valign="top" charoff="50">Tb.Sp</td><td align="left" valign="top" charoff="50">mm</td><td align="left" valign="top" charoff="50">(2/1.199)(A<sub>T</sub>−A<sub>B</sub>)/P<sub>B</sub></td><td align="left" valign="top" charoff="50">1/Tb.N–Tb.Th</td></tr><tr><td align="left" valign="top" charoff="50">Trabecular number</td><td align="left" valign="top" charoff="50">Tb.N</td><td align="left" valign="top" charoff="50">mm<sup>−1</sup></td><td align="left" valign="top" charoff="50">(1.199/2)(P<sub>B</sub>/A<sub>T</sub>)</td><td align="left" valign="top" charoff="50">(BV/TV)/Tb.Th</td></tr></tbody></table><table-wrap-foot><fn id="t2-tfoot1"><p>Abbreviations: A<sub>B</sub>, bone area; A<sub>T</sub>, total area; BS, bone surface; BV, bone volume; P<sub>B</sub>, bone perimeter; TV, tissue volume.</p></fn></table-wrap-foot></table-wrap><table-wrap id="tbl3"><label>Table 3</label><caption><title>Comparison of morphometric parameters obtained by CBCT and histology</title></caption><table frame="hsides" rules="groups" border="1"><colgroup><col align="left"></col><col align="left"></col><col align="left"></col><col align="left"></col><col align="left"></col><col align="left"></col><col align="left"></col></colgroup><thead valign="bottom"><tr><th rowspan="2" align="left" valign="top" charoff="50">Morphometric parameters</th><th colspan="2" align="center" valign="top" charoff="50">CBCT<hr></hr></th><th colspan="2" align="center" valign="top" charoff="50">Histology<hr></hr></th><th align="left" valign="top" charoff="50">Wilcoxon</th><th align="left" valign="top" charoff="50">Spearman’s</th></tr><tr><th align="left" valign="top" charoff="50">Mean±s.d.</th><th align="left" valign="top" charoff="50">CV</th><th align="left" valign="top" charoff="50">Mean±s.d.</th><th align="left" valign="top" charoff="50">CV</th><th align="left" valign="top" charoff="50"><italic>P</italic></th><th align="left" valign="top" charoff="50"><italic>r</italic> (<italic>P</italic>)</th></tr></thead><tbody valign="top"><tr><td align="left" valign="top" charoff="50">Bone with implant (<italic>n</italic>=27)</td><td align="left" valign="top" charoff="50"> </td><td align="left" valign="top" charoff="50"> </td><td align="left" valign="top" charoff="50"> </td><td align="left" valign="top" charoff="50"> </td><td align="left" valign="top" charoff="50"> </td><td align="left" valign="top" charoff="50"> </td></tr><tr><td align="left" valign="top" charoff="50"> (BV/TV)/%</td><td align="left" valign="top" charoff="50">39.21±9.21</td><td align="left" valign="top" charoff="50">0.23</td><td align="left" valign="top" charoff="50">62.7±11.9</td><td align="left" valign="top" charoff="50">0.19</td><td align="left" valign="top" charoff="50"><0.001</td><td align="left" valign="top" charoff="50">0.65 (<0.001)</td></tr><tr><td align="left" valign="top" charoff="50"> Tb.Th/mm</td><td align="left" valign="top" charoff="50">0.43±0.05</td><td align="left" valign="top" charoff="50">0.11</td><td align="left" valign="top" charoff="50">0.31±0.02</td><td align="left" valign="top" charoff="50">0.07</td><td align="left" valign="top" charoff="50"><0.001</td><td align="left" valign="top" charoff="50">0.75 (<0.001)</td></tr><tr><td align="left" valign="top" charoff="50"> Tb.Sp/mm</td><td align="left" valign="top" charoff="50">0.57±0.13</td><td align="left" valign="top" charoff="50">0.22</td><td align="left" valign="top" charoff="50">0.29±0.10</td><td align="left" valign="top" charoff="50">0.35</td><td align="left" valign="top" charoff="50"><0.001</td><td align="left" valign="top" charoff="50">0.67 (<0.001)</td></tr><tr><td align="left" valign="top" charoff="50"> Tb.N/mm<sup>−1</sup></td><td align="left" valign="top" charoff="50">1.19±0.21</td><td align="left" valign="top" charoff="50">0.25</td><td align="left" valign="top" charoff="50">1.99±0.37</td><td align="left" valign="top" charoff="50">0.19</td><td align="left" valign="top" charoff="50"><0.001</td><td align="left" valign="top" charoff="50">0.85 (<0.001)</td></tr><tr><td align="left" valign="top" charoff="50">Bone without implant (<italic>n</italic>=9)</td><td align="left" valign="top" charoff="50"> </td><td align="left" valign="top" charoff="50"> </td><td align="left" valign="top" charoff="50"> </td><td align="left" valign="top" charoff="50"> </td><td align="left" valign="top" charoff="50"> </td><td align="left" valign="top" charoff="50"> </td></tr><tr><td align="left" valign="top" charoff="50"> (BV/TV)/%</td><td align="left" valign="top" charoff="50">36.26±6.15</td><td align="left" valign="top" charoff="50">0.33</td><td align="left" valign="top" charoff="50">50.50±7.72</td><td align="left" valign="top" charoff="50">0.16</td><td align="left" valign="top" charoff="50"><0.001</td><td align="left" valign="top" charoff="50">0.82 (<0.006)</td></tr><tr><td align="left" valign="top" charoff="50"> Tb.Th/mm</td><td align="left" valign="top" charoff="50">0.47±0.08</td><td align="left" valign="top" charoff="50">0.17</td><td align="left" valign="top" charoff="50">0.35±0.04</td><td align="left" valign="top" charoff="50">0.02</td><td align="left" valign="top" charoff="50"><0.001</td><td align="left" valign="top" charoff="50">0.68 (<0.04)</td></tr><tr><td align="left" valign="top" charoff="50"> Tb.Sp/mm</td><td align="left" valign="top" charoff="50">0.77±0.23</td><td align="left" valign="top" charoff="50">0.30</td><td align="left" valign="top" charoff="50">0.52±0.26</td><td align="left" valign="top" charoff="50">0.51</td><td align="left" valign="top" charoff="50"><0.001</td><td align="left" valign="top" charoff="50">0.88 (<0.002)</td></tr><tr><td align="left" valign="top" charoff="50"> Tb.N/mm<sup>−1</sup></td><td align="left" valign="top" charoff="50">0.73±0.13</td><td align="left" valign="top" charoff="50">0.19</td><td align="left" valign="top" charoff="50">1.38±0.29</td><td align="left" valign="top" charoff="50">0.21</td><td align="left" valign="top" charoff="50"><0.001</td><td align="left" valign="top" charoff="50">0.94 (<0.001)</td></tr></tbody></table><table-wrap-foot><fn id="t3-tfoot1"><p>Abbreviations: BV/TV, bone volume fraction; CBCT, cone-beam computed tomography; CV, coefficient of variation; s.d., standard deviation; Tb.N, trabecular number; Tb.Sp, trabecular separation; Tb.Th, trabecular thickness.</p></fn></table-wrap-foot></table-wrap></floats-group></pmc><affiliations><list><country><li>Belgique</li><li>Brésil</li><li>Roumanie</li><li>République populaire de Chine</li></country></list><tree><country name="Belgique"><noRegion><name sortKey="Huang, Yan" sort="Huang, Yan" uniqKey="Huang Y" first="Yan" last="Huang">Yan Huang</name></noRegion><name sortKey="Depypere, Maarten" sort="Depypere, Maarten" uniqKey="Depypere M" first="Maarten" last="Depypere">Maarten Depypere</name><name sortKey="Dessel, Jeroen Van" sort="Dessel, Jeroen Van" uniqKey="Dessel J" first="Jeroen Van" last="Dessel">Jeroen Van Dessel</name><name sortKey="Ezeldeen, Mostafa" sort="Ezeldeen, Mostafa" uniqKey="Ezeldeen M" first="Mostafa" last="Ezeldeen">Mostafa Ezeldeen</name><name sortKey="Jacobs, Reinhilde" sort="Jacobs, Reinhilde" uniqKey="Jacobs R" first="Reinhilde" last="Jacobs">Reinhilde Jacobs</name><name sortKey="Lambrichts, Ivo" sort="Lambrichts, Ivo" uniqKey="Lambrichts I" first="Ivo" last="Lambrichts">Ivo Lambrichts</name></country><country name="République populaire de Chine"><noRegion><name sortKey="Huang, Yan" sort="Huang, Yan" uniqKey="Huang Y" first="Yan" last="Huang">Yan Huang</name></noRegion><name sortKey="Liang, Xin" sort="Liang, Xin" uniqKey="Liang X" first="Xin" last="Liang">Xin Liang</name></country><country name="Roumanie"><noRegion><name sortKey="Iliescu, Alexandru Andrei" sort="Iliescu, Alexandru Andrei" uniqKey="Iliescu A" first="Alexandru Andrei" last="Iliescu">Alexandru Andrei Iliescu</name></noRegion></country><country name="Brésil"><noRegion><name sortKey="Santos, Emanuela Dos" sort="Santos, Emanuela Dos" uniqKey="Santos E" first="Emanuela Dos" last="Santos">Emanuela Dos Santos</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Ncbi/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 005E49 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd -nk 005E49 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= EdenteV2
|flux= Ncbi
|étape= Merge
|type= RBID
|clé= PMC:4472132
|texte= Validating cone-beam computed tomography for peri-implant bone morphometric analysis
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/RBID.i -Sk "pubmed:26273522" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd \
| NlmPubMed2Wicri -a EdenteV2
| This area was generated with Dilib version V0.6.32. |  |