Computer Tomograph (CT) imaging of mandibular anatomical substrate in animal model restored with nanostructured hydroxyapatite compounds
Identifieur interne : 005A87 ( Ncbi/Merge ); précédent : 005A86; suivant : 005A88Computer Tomograph (CT) imaging of mandibular anatomical substrate in animal model restored with nanostructured hydroxyapatite compounds
Auteurs : R. Ciuluvic [Roumanie] ; S. Gr Dinaru [Roumanie] ; M. Popescu [Roumanie] ; Rm Piticescu [Roumanie] ; R. Cergan [Roumanie]Source :
- Journal of Medicine and Life [ 1844-122X ] ; 2015.
Abstract
Url:
PubMed: 25914749
PubMed Central: 4397532
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Computer Tomograph (CT) imaging of mandibular anatomical substrate in animal model restored with nanostructured hydroxyapatite compounds</title><author><name sortKey="Ciuluvic, R" sort="Ciuluvic, R" uniqKey="Ciuluvic R" first="R" last="Ciuluvic">R. Ciuluvic</name><affiliation wicri:level="1"><nlm:aff id="A1">Anatomy Department, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania</nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea>Anatomy Department, “Carol Davila” University of Medicine and Pharmacy, Bucharest</wicri:regionArea><wicri:noRegion>Bucharest</wicri:noRegion></affiliation></author><author><name sortKey="Gr Dinaru, S" sort="Gr Dinaru, S" uniqKey="Gr Dinaru S" first="S" last="Gr Dinaru">S. Gr Dinaru</name><affiliation wicri:level="1"><nlm:aff id="A2">Ophthalmology Department, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania</nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea>Ophthalmology Department, “Carol Davila” University of Medicine and Pharmacy, Bucharest</wicri:regionArea><wicri:noRegion>Bucharest</wicri:noRegion></affiliation></author><author><name sortKey="Popescu, M" sort="Popescu, M" uniqKey="Popescu M" first="M" last="Popescu">M. Popescu</name><affiliation wicri:level="1"><nlm:aff id="A3">Institute for Nonferous and Rare Materials, Bucharest, Romania</nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea>Institute for Nonferous and Rare Materials, Bucharest</wicri:regionArea><wicri:noRegion>Bucharest</wicri:noRegion></affiliation></author><author><name sortKey="Piticescu, Rm" sort="Piticescu, Rm" uniqKey="Piticescu R" first="Rm" last="Piticescu">Rm Piticescu</name><affiliation wicri:level="1"><nlm:aff id="A3">Institute for Nonferous and Rare Materials, Bucharest, Romania</nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea>Institute for Nonferous and Rare Materials, Bucharest</wicri:regionArea><wicri:noRegion>Bucharest</wicri:noRegion></affiliation></author><author><name sortKey="Cergan, R" sort="Cergan, R" uniqKey="Cergan R" first="R" last="Cergan">R. Cergan</name><affiliation wicri:level="1"><nlm:aff id="A3">Institute for Nonferous and Rare Materials, Bucharest, Romania</nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea>Institute for Nonferous and Rare Materials, Bucharest</wicri:regionArea><wicri:noRegion>Bucharest</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25914749</idno><idno type="pmc">4397532</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397532</idno><idno type="RBID">PMC:4397532</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">001E70</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001E70</idno><idno type="wicri:Area/Pmc/Curation">001E70</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001E70</idno><idno type="wicri:Area/Pmc/Checkpoint">000F25</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000F25</idno><idno type="wicri:Area/Ncbi/Merge">005A87</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Computer Tomograph (CT) imaging of mandibular anatomical substrate in animal model restored with nanostructured hydroxyapatite compounds</title><author><name sortKey="Ciuluvic, R" sort="Ciuluvic, R" uniqKey="Ciuluvic R" first="R" last="Ciuluvic">R. Ciuluvic</name><affiliation wicri:level="1"><nlm:aff id="A1">Anatomy Department, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania</nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea>Anatomy Department, “Carol Davila” University of Medicine and Pharmacy, Bucharest</wicri:regionArea><wicri:noRegion>Bucharest</wicri:noRegion></affiliation></author><author><name sortKey="Gr Dinaru, S" sort="Gr Dinaru, S" uniqKey="Gr Dinaru S" first="S" last="Gr Dinaru">S. Gr Dinaru</name><affiliation wicri:level="1"><nlm:aff id="A2">Ophthalmology Department, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania</nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea>Ophthalmology Department, “Carol Davila” University of Medicine and Pharmacy, Bucharest</wicri:regionArea><wicri:noRegion>Bucharest</wicri:noRegion></affiliation></author><author><name sortKey="Popescu, M" sort="Popescu, M" uniqKey="Popescu M" first="M" last="Popescu">M. Popescu</name><affiliation wicri:level="1"><nlm:aff id="A3">Institute for Nonferous and Rare Materials, Bucharest, Romania</nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea>Institute for Nonferous and Rare Materials, Bucharest</wicri:regionArea><wicri:noRegion>Bucharest</wicri:noRegion></affiliation></author><author><name sortKey="Piticescu, Rm" sort="Piticescu, Rm" uniqKey="Piticescu R" first="Rm" last="Piticescu">Rm Piticescu</name><affiliation wicri:level="1"><nlm:aff id="A3">Institute for Nonferous and Rare Materials, Bucharest, Romania</nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea>Institute for Nonferous and Rare Materials, Bucharest</wicri:regionArea><wicri:noRegion>Bucharest</wicri:noRegion></affiliation></author><author><name sortKey="Cergan, R" sort="Cergan, R" uniqKey="Cergan R" first="R" last="Cergan">R. Cergan</name><affiliation wicri:level="1"><nlm:aff id="A3">Institute for Nonferous and Rare Materials, Bucharest, Romania</nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea>Institute for Nonferous and Rare Materials, Bucharest</wicri:regionArea><wicri:noRegion>Bucharest</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of Medicine and Life</title><idno type="ISSN">1844-122X</idno><idno type="eISSN">1844-3117</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><bold>Introduction:</bold> This study was meant to test a new type of bone graft on an animal model. This material was a nanostructured hydroxyapatite.</p><p><bold>Materials and Methods:</bold> the study was conducted according to Ethic Committee Regulation on animal model (Oryctolagus cuniculus – rabbit) between August and November 2014, at “Carol Davila” University of Medicine and Pharmacy, Bucharest. The animals were tested by using a CT at the level of the mandible before and after using the nanostructured hydroxyapatite.</p><p><bold>Results:</bold> The animals were CT scanned at 1, 2 and respectively 3 months, noticing a growth of the mandibular bone density. After 3 months, a bone density equal with the density of the healthy bone was noticed.</p><p><bold>Conclusions:</bold> The use of the bone graft could be a viable alternative to available materials. The advantage was that bone recovery had a density similar to the density of the healthy bone and the cost of production was low because it was made out of Calcium azotate and monobasic ammonium phosphate.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Dumitrescu, Al" uniqKey="Dumitrescu A">AL Dumitrescu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lindhe, J" uniqKey="Lindhe J">J Lindhe</name></author><author><name sortKey="Lang, Np" uniqKey="Lang N">NP Lang</name></author><author><name sortKey="Karring, T" uniqKey="Karring T">T Karring</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Misch, Ce" uniqKey="Misch C">CE Misch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zitzmann, Nu" uniqKey="Zitzmann N">NU Zitzmann</name></author><author><name sortKey="Marinello, Cp" uniqKey="Marinello C">CP Marinello</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kumar, P" uniqKey="Kumar P">P Kumar</name></author><author><name sortKey="Belliappa, V" uniqKey="Belliappa V">V Belliappa</name></author><author><name sortKey="Ghousia, F" uniqKey="Ghousia F">F Ghousia</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Conrad, Eu" uniqKey="Conrad E">EU Conrad</name></author><author><name sortKey="Gretch, Dr" uniqKey="Gretch D">DR Gretch</name></author><author><name sortKey="Obermeyer, Kr" uniqKey="Obermeyer K">KR Obermeyer</name></author><author><name sortKey="Moogk, Ms" uniqKey="Moogk M">MS Moogk</name></author><author><name sortKey="Sayers, M" uniqKey="Sayers M">M Sayers</name></author><author><name sortKey="Wilson, Jj" uniqKey="Wilson J">JJ Wilson</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Valdes, Ma" uniqKey="Valdes M">MA Valdes</name></author><author><name sortKey="Thakur, Na" uniqKey="Thakur N">NA Thakur</name></author><author><name sortKey="Namdari, S" uniqKey="Namdari S">S Namdari</name></author><author><name sortKey="Ciombor, Dm" uniqKey="Ciombor D">DM Ciombor</name></author><author><name sortKey="Palumbo, M" uniqKey="Palumbo M">M Palumbo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mulconrey, Ds" uniqKey="Mulconrey D">DS Mulconrey</name></author><author><name sortKey="Birdwell, Kh" uniqKey="Birdwell K">KH Birdwell</name></author><author><name sortKey="Flynn, J" uniqKey="Flynn J">J Flynn</name></author><author><name sortKey="Cronen, Ga" uniqKey="Cronen G">GA Cronen</name></author><author><name sortKey="Rose, Ps" uniqKey="Rose P">PS Rose</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Waked, W" uniqKey="Waked W">W Waked</name></author><author><name sortKey="Grauer, J" uniqKey="Grauer J">J Grauer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Giannoudis, Pv" uniqKey="Giannoudis P">PV Giannoudis</name></author><author><name sortKey="Dinopoulos, H" uniqKey="Dinopoulos H">H Dinopoulos</name></author><author><name sortKey="Tsiridis, E" uniqKey="Tsiridis E">E Tsiridis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ogle, Oe" uniqKey="Ogle O">OE Ogle</name></author><author><name sortKey="Byles, N" uniqKey="Byles N">N Byles</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Popescu, M" uniqKey="Popescu M">M Popescu</name></author><author><name sortKey="Meghea, A" uniqKey="Meghea A">A Meghea</name></author><author><name sortKey="Piticescu, Rm" uniqKey="Piticescu R">RM Piticescu</name></author><author><name sortKey="Vasile, E" uniqKey="Vasile E">E Vasile</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Piticescu, Rm" uniqKey="Piticescu R">RM Piticescu</name></author><author><name sortKey="Popescu, Lm" uniqKey="Popescu L">LM Popescu</name></author><author><name sortKey="Meghea, A" uniqKey="Meghea A">A Meghea</name></author><author><name sortKey="Badilita, V" uniqKey="Badilita V">V Badilita</name></author><author><name sortKey="Vasile, E" uniqKey="Vasile E">E Vasile</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Harriott, Vj" uniqKey="Harriott V">VJ Harriott</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Popescu, Lm" uniqKey="Popescu L">LM Popescu</name></author><author><name sortKey="Rusti, Cf" uniqKey="Rusti C">CF Rusti</name></author><author><name sortKey="Piticescu, Rm" uniqKey="Piticescu R">RM Piticescu</name></author><author><name sortKey="Valero, T" uniqKey="Valero T">T Valero</name></author><author><name sortKey="Kintzios, S" uniqKey="Kintzios S">S Kintzios</name></author><author><name sortKey="Buruiana, T" uniqKey="Buruiana T">T Buruiana</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Popescu, Lm" uniqKey="Popescu L">LM Popescu</name></author><author><name sortKey="Piticescu, Rm" uniqKey="Piticescu R">RM Piticescu</name></author><author><name sortKey="Buruiana, T" uniqKey="Buruiana T">T Buruiana</name></author><author><name sortKey="Vasile, E" uniqKey="Vasile E">E Vasile</name></author><author><name sortKey="Trusca, R" uniqKey="Trusca R">R Trusca</name></author><author><name sortKey="Badilita, V" uniqKey="Badilita V">V Badilita</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Piticescu, Rm" uniqKey="Piticescu R">RM Piticescu</name></author><author><name sortKey="Popescu, Lm" uniqKey="Popescu L">LM Popescu</name></author><author><name sortKey="Buruiana, T" uniqKey="Buruiana T">T Buruiana</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="case-report"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Med Life</journal-id><journal-id journal-id-type="iso-abbrev">J Med Life</journal-id><journal-id journal-id-type="publisher-id">JMedLife</journal-id><journal-title-group><journal-title>Journal of Medicine and Life</journal-title></journal-title-group><issn pub-type="ppub">1844-122X</issn><issn pub-type="epub">1844-3117</issn><publisher><publisher-name>Carol Davila University Press</publisher-name><publisher-loc>Romania</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">25914749</article-id><article-id pub-id-type="pmc">4397532</article-id><article-id pub-id-type="publisher-id">JMedLife-08-99</article-id><article-categories><subj-group subj-group-type="heading"><subject>Case Presentations</subject></subj-group></article-categories><title-group><article-title>Computer Tomograph (CT) imaging of mandibular anatomical substrate in animal model restored with nanostructured hydroxyapatite compounds</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Ciuluvică</surname><given-names>R</given-names></name><xref ref-type="aff" rid="A1">*</xref></contrib><contrib contrib-type="author"><name><surname>Grădinaru</surname><given-names>S</given-names></name><xref ref-type="aff" rid="A2">**</xref></contrib><contrib contrib-type="author"><name><surname>Popescu</surname><given-names>M</given-names></name><xref ref-type="aff" rid="A3">***</xref></contrib><contrib contrib-type="author"><name><surname>Piticescu</surname><given-names>RM</given-names></name><xref ref-type="aff" rid="A3">***</xref></contrib><contrib contrib-type="author"><name><surname>Cergan</surname><given-names>R</given-names></name><xref ref-type="aff" rid="A3">***</xref></contrib></contrib-group><aff id="A1"><label>*</label>Anatomy Department, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania</aff><aff id="A2"><label>**</label>Ophthalmology Department, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania</aff><aff id="A3"><label>***</label>Institute for Nonferous and Rare Materials, Bucharest, Romania</aff><author-notes><corresp><bold>Correspondence to:</bold>Gradinaru S, MD
Ophthalmology Department, “Carol Davila” University of Medicine and Pharmacy
8 Eroilor Sanitari Blvd., Bucharest, Romania,
Mobile phone: +40 726 535 515, E-mail: sanzinic@yahoo.com
</corresp></author-notes><pub-date pub-type="ppub"><season>Jan-Mar</season><year>2015</year></pub-date><volume>8</volume><issue>1</issue><fpage>99</fpage><lpage>102</lpage><history><date date-type="received"><day>24</day><month>8</month><year>2014</year></date><date date-type="accepted"><day>17</day><month>12</month><year>2014</year></date></history><permissions><copyright-statement>©Carol Davila University Press
</copyright-statement><copyright-year>2014</copyright-year><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/2.0/"><license-p>This is
an open-access article distributed under the terms of the Creative
Commons Attribution License, which permits unrestricted use,
distribution, and reproduction in any medium, provided the original work
is properly cited.</license-p></license></permissions><abstract><p><bold>Introduction:</bold> This study was meant to test a new type of bone graft on an animal model. This material was a nanostructured hydroxyapatite.</p><p><bold>Materials and Methods:</bold> the study was conducted according to Ethic Committee Regulation on animal model (Oryctolagus cuniculus – rabbit) between August and November 2014, at “Carol Davila” University of Medicine and Pharmacy, Bucharest. The animals were tested by using a CT at the level of the mandible before and after using the nanostructured hydroxyapatite.</p><p><bold>Results:</bold> The animals were CT scanned at 1, 2 and respectively 3 months, noticing a growth of the mandibular bone density. After 3 months, a bone density equal with the density of the healthy bone was noticed.</p><p><bold>Conclusions:</bold> The use of the bone graft could be a viable alternative to available materials. The advantage was that bone recovery had a density similar to the density of the healthy bone and the cost of production was low because it was made out of Calcium azotate and monobasic ammonium phosphate.</p></abstract><kwd-group><kwd>hydroxyapatite</kwd><kwd>dental implant</kwd><kwd>bone reconstruction</kwd><kwd>nanostructured polymers</kwd></kwd-group></article-meta></front></pmc><affiliations><list><country><li>Roumanie</li></country></list><tree><country name="Roumanie"><noRegion><name sortKey="Ciuluvic, R" sort="Ciuluvic, R" uniqKey="Ciuluvic R" first="R" last="Ciuluvic">R. Ciuluvic</name></noRegion><name sortKey="Cergan, R" sort="Cergan, R" uniqKey="Cergan R" first="R" last="Cergan">R. Cergan</name><name sortKey="Gr Dinaru, S" sort="Gr Dinaru, S" uniqKey="Gr Dinaru S" first="S" last="Gr Dinaru">S. Gr Dinaru</name><name sortKey="Piticescu, Rm" sort="Piticescu, Rm" uniqKey="Piticescu R" first="Rm" last="Piticescu">Rm Piticescu</name><name sortKey="Popescu, M" sort="Popescu, M" uniqKey="Popescu M" first="M" last="Popescu">M. Popescu</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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