Assessment of interleukin-1beta and interleukin-6 in the crevicular fluid around healthy implants, implants with peri-implantitis, and healthy teeth: a cross-sectional study
Identifieur interne : 005605 ( Ncbi/Merge ); précédent : 005604; suivant : 005606Assessment of interleukin-1beta and interleukin-6 in the crevicular fluid around healthy implants, implants with peri-implantitis, and healthy teeth: a cross-sectional study
Auteurs : Siamak Yaghobee [Iran] ; Afshin Khorsand [Iran] ; Amir Alireza Rasouli Ghohroudi [Iran] ; Khashayar Sanjari [Iran] ; Mahdi Kadkhodazadeh [Iran]Source :
- Journal of the Korean Association of Oral and Maxillofacial Surgeons [ 2234-7550 ] ; 2014.
Abstract
This study aimed to assess and compare the levels of interleukin-1beta (IL-1β) and interleukin-6 (IL-6) in the crevicular fluid around healthy implants, implants with peri-implantitis, and healthy teeth.
This study evaluated 16 dental implants in 8 patients (4 males and 4 females). These patients had at least one healthy implant and one implant with peri-implantitis next to healthy teeth. The crevicular fluid was collected using absorbent cones and transferred to the laboratory. Specimens were evaluated by ELISA for interleukin levels. Data were analyzed using repeated measures ANOVA and Bonferroni tests (
Levels of IL-1β in the crevicular fluid around implants with peri-implantitis were significantly higher than around healthy implants (
Within the limitations of this study, significant differences exist in the levels of IL-1β and IL-6 in the crevicular fluid of implants with peri-implantitis, healthy implants, and healthy teeth. More studies with larger sample sizes in different populations are necessary.
Url:
DOI: 10.5125/jkaoms.2014.40.5.220
PubMed: 25368834
PubMed Central: 4217267
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University of Medical Sciences, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation></author><author><name sortKey="Khorsand, Afshin" sort="Khorsand, Afshin" uniqKey="Khorsand A" first="Afshin" last="Khorsand">Afshin Khorsand</name><affiliation wicri:level="1"><nlm:aff id="A1">Department of Periodontics, Tehran University of Medical Sciences, Tehran, Iran.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iran</country><wicri:regionArea>Department of Periodontics, Tehran University of Medical Sciences, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation></author><author><name sortKey="Rasouli Ghohroudi, Amir Alireza" sort="Rasouli Ghohroudi, Amir Alireza" uniqKey="Rasouli Ghohroudi A" first="Amir Alireza" last="Rasouli Ghohroudi">Amir Alireza Rasouli Ghohroudi</name><affiliation wicri:level="1"><nlm:aff id="A1">Department of Periodontics, Tehran University of Medical Sciences, Tehran, Iran.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iran</country><wicri:regionArea>Department of Periodontics, Tehran University of Medical Sciences, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation></author><author><name sortKey="Sanjari, Khashayar" sort="Sanjari, Khashayar" uniqKey="Sanjari K" first="Khashayar" last="Sanjari">Khashayar Sanjari</name><affiliation wicri:level="1"><nlm:aff id="A3">Private Practice, Tehran, Iran.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iran</country><wicri:regionArea>Private Practice, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation></author><author><name sortKey="Kadkhodazadeh, Mahdi" sort="Kadkhodazadeh, Mahdi" uniqKey="Kadkhodazadeh M" first="Mahdi" last="Kadkhodazadeh">Mahdi Kadkhodazadeh</name><affiliation wicri:level="1"><nlm:aff id="A4">Department of Periodontics, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.</nlm:aff><country xml:lang="fr" 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type="wicri:Area/Ncbi/Merge">005605</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Assessment of interleukin-1beta and interleukin-6 in the crevicular fluid around healthy implants, implants with peri-implantitis, and healthy teeth: a cross-sectional study</title><author><name sortKey="Yaghobee, Siamak" sort="Yaghobee, Siamak" uniqKey="Yaghobee S" first="Siamak" last="Yaghobee">Siamak Yaghobee</name><affiliation wicri:level="1"><nlm:aff id="A1">Department of Periodontics, Tehran University of Medical Sciences, Tehran, Iran.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iran</country><wicri:regionArea>Department of Periodontics, Tehran University of Medical Sciences, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A2">Dental Implant Research Center, Tehran University of Medical Sciences, Tehran, Iran.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iran</country><wicri:regionArea>Dental Implant Research Center, Tehran University of Medical Sciences, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation></author><author><name sortKey="Khorsand, Afshin" sort="Khorsand, Afshin" uniqKey="Khorsand A" first="Afshin" last="Khorsand">Afshin Khorsand</name><affiliation wicri:level="1"><nlm:aff id="A1">Department of Periodontics, Tehran University of Medical Sciences, Tehran, Iran.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iran</country><wicri:regionArea>Department of Periodontics, Tehran University of Medical Sciences, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation></author><author><name sortKey="Rasouli Ghohroudi, Amir Alireza" sort="Rasouli Ghohroudi, Amir Alireza" uniqKey="Rasouli Ghohroudi A" first="Amir Alireza" last="Rasouli Ghohroudi">Amir Alireza Rasouli Ghohroudi</name><affiliation wicri:level="1"><nlm:aff id="A1">Department of Periodontics, Tehran University of Medical Sciences, Tehran, Iran.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iran</country><wicri:regionArea>Department of Periodontics, Tehran University of Medical Sciences, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation></author><author><name sortKey="Sanjari, Khashayar" sort="Sanjari, Khashayar" uniqKey="Sanjari K" first="Khashayar" last="Sanjari">Khashayar Sanjari</name><affiliation wicri:level="1"><nlm:aff id="A3">Private Practice, Tehran, Iran.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iran</country><wicri:regionArea>Private Practice, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation></author><author><name sortKey="Kadkhodazadeh, Mahdi" sort="Kadkhodazadeh, Mahdi" uniqKey="Kadkhodazadeh M" first="Mahdi" last="Kadkhodazadeh">Mahdi Kadkhodazadeh</name><affiliation wicri:level="1"><nlm:aff id="A4">Department of Periodontics, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iran</country><wicri:regionArea>Department of Periodontics, Dental School, Shahid Beheshti University of Medical Sciences, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of the Korean Association of Oral and Maxillofacial Surgeons</title><idno type="ISSN">2234-7550</idno><idno type="eISSN">2234-5930</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Objectives</title><p>This study aimed to assess and compare the levels of interleukin-1beta (IL-1β) and interleukin-6 (IL-6) in the crevicular fluid around healthy implants, implants with peri-implantitis, and healthy teeth.</p></sec><sec><title>Materials and Methods</title><p>This study evaluated 16 dental implants in 8 patients (4 males and 4 females). These patients had at least one healthy implant and one implant with peri-implantitis next to healthy teeth. The crevicular fluid was collected using absorbent cones and transferred to the laboratory. Specimens were evaluated by ELISA for interleukin levels. Data were analyzed using repeated measures ANOVA and Bonferroni tests (<italic>P</italic><0.05).</p></sec><sec><title>Results</title><p>Levels of IL-1β in the crevicular fluid around implants with peri-implantitis were significantly higher than around healthy implants (<italic>P</italic>=0.002); the latter was significantly higher than around healthy teeth (<italic>P</italic>=0.015). A significant difference was found in the level of IL-6 in the crevicular fluid around implants with peri-implantitis and healthy implants (<italic>P</italic>=0.049) and also between implants with peri-implantitis and healthy teeth (<italic>P</italic><0.001).</p></sec><sec><title>Conclusion</title><p>Within the limitations of this study, significant differences exist in the levels of IL-1β and IL-6 in the crevicular fluid of implants with peri-implantitis, healthy implants, and healthy teeth. More studies with larger sample sizes in different populations are necessary.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Abrishami, Mr" uniqKey="Abrishami M">MR Abrishami</name></author><author><name sortKey="Sabour, S" uniqKey="Sabour S">S Sabour</name></author><author><name sortKey="Nasiri, M" uniqKey="Nasiri M">M Nasiri</name></author><author><name sortKey="Amid, R" uniqKey="Amid R">R Amid</name></author><author><name sortKey="Kadkhodazadeh, M" uniqKey="Kadkhodazadeh M">M Kadkhodazadeh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Roos Jans Ker, Am" uniqKey="Roos Jans Ker A">AM Roos-Jansåker</name></author><author><name sortKey="Lindahl, C" uniqKey="Lindahl C">C Lindahl</name></author><author><name sortKey="Renvert, H" uniqKey="Renvert H">H Renvert</name></author><author><name sortKey="Renvert, S" uniqKey="Renvert S">S Renvert</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ata Ali, J" uniqKey="Ata Ali J">J Ata-Ali</name></author><author><name sortKey="Flichy Fernandez, Aj" uniqKey="Flichy Fernandez A">AJ Flichy-Fernandez</name></author><author><name sortKey="Ata Ali, F" uniqKey="Ata Ali F">F Ata-Ali</name></author><author><name sortKey="Penarrocha Diago, M" uniqKey="Penarrocha Diago M">M Penarrocha-Diago</name></author><author><name sortKey="Penarrocha Diago, M" uniqKey="Penarrocha Diago M">M Penarrocha-Diago</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Petkovi, Ab" uniqKey="Petkovi A">AB Petković</name></author><author><name sortKey="Mati, Sm" uniqKey="Mati S">SM Matić</name></author><author><name sortKey="Stamatovi, Nv" uniqKey="Stamatovi N">NV Stamatović</name></author><author><name sortKey="Vojvodi, Dv" uniqKey="Vojvodi D">DV Vojvodić</name></author><author><name sortKey="Todorovi, Tm" uniqKey="Todorovi T">TM Todorović</name></author><author><name sortKey="Lazi, Zr" uniqKey="Lazi Z">ZR Lazić</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sanz, M" uniqKey="Sanz M">M Sanz</name></author><author><name sortKey="Chapple, Il" uniqKey="Chapple I">IL Chapple</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Greenstein, G" uniqKey="Greenstein G">G Greenstein</name></author><author><name sortKey="Caton, J" uniqKey="Caton J">J Caton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dennison, Dk" uniqKey="Dennison D">DK Dennison</name></author><author><name sortKey="Van Dyke, Te" uniqKey="Van Dyke T">TE Van Dyke</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Okada, H" uniqKey="Okada H">H Okada</name></author><author><name sortKey="Murakami, S" uniqKey="Murakami S">S Murakami</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Panagakos, Fs" uniqKey="Panagakos F">FS Panagakos</name></author><author><name sortKey="Aboyoussef, H" uniqKey="Aboyoussef H">H Aboyoussef</name></author><author><name sortKey="Dondero, R" uniqKey="Dondero R">R Dondero</name></author><author><name sortKey="Jandinski, Jj" uniqKey="Jandinski J">JJ Jandinski</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stashenko, P" uniqKey="Stashenko P">P Stashenko</name></author><author><name sortKey="Fujiyoshi, P" uniqKey="Fujiyoshi P">P Fujiyoshi</name></author><author><name sortKey="Obernesser, Ms" uniqKey="Obernesser M">MS Obernesser</name></author><author><name sortKey="Prostak, L" uniqKey="Prostak L">L Prostak</name></author><author><name sortKey="Haffajee, Ad" uniqKey="Haffajee A">AD Haffajee</name></author><author><name sortKey="Socransky, Ss" uniqKey="Socransky S">SS Socransky</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ataoglu, H" uniqKey="Ataoglu H">H Ataoglu</name></author><author><name sortKey="Alptekin, No" uniqKey="Alptekin N">NO Alptekin</name></author><author><name sortKey="Haliloglu, S" uniqKey="Haliloglu S">S Haliloglu</name></author><author><name sortKey="Gursel, M" uniqKey="Gursel M">M Gursel</name></author><author><name sortKey="Ataoglu, T" uniqKey="Ataoglu T">T Ataoglu</name></author><author><name sortKey="Serpek, B" uniqKey="Serpek B">B Serpek</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kadkhodazadeh, M" uniqKey="Kadkhodazadeh M">M Kadkhodazadeh</name></author><author><name sortKey="Esfahrood, Zr" uniqKey="Esfahrood Z">ZR Esfahrood</name></author><author><name sortKey="Amid, R" uniqKey="Amid R">R Amid</name></author><author><name sortKey="Zarnegarnia, P" uniqKey="Zarnegarnia P">P Zarnegarnia</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Griffiths, Gs" uniqKey="Griffiths G">GS Griffiths</name></author><author><name sortKey="Curtis, Ma" uniqKey="Curtis M">MA Curtis</name></author><author><name sortKey="Wilton, Jm" uniqKey="Wilton J">JM Wilton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Page, Rc" uniqKey="Page R">RC Page</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Casado, Pl" uniqKey="Casado P">PL Casado</name></author><author><name sortKey="Canullo, L" uniqKey="Canullo L">L Canullo</name></author><author><name sortKey="De Almeida Filardy, A" uniqKey="De Almeida Filardy A">A de Almeida Filardy</name></author><author><name sortKey="Granjeiro, Jm" uniqKey="Granjeiro J">JM Granjeiro</name></author><author><name sortKey="Barboza, Ep" uniqKey="Barboza E">EP Barboza</name></author><author><name sortKey="Leite Duarte, Me" uniqKey="Leite Duarte M">ME Leite Duarte</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nowzari, H" uniqKey="Nowzari H">H Nowzari</name></author><author><name sortKey="Botero, Je" uniqKey="Botero J">JE Botero</name></author><author><name sortKey="Degiacomo, M" uniqKey="Degiacomo M">M DeGiacomo</name></author><author><name sortKey="Villacres, Mc" uniqKey="Villacres M">MC Villacres</name></author><author><name sortKey="Rich, Sk" uniqKey="Rich S">SK Rich</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Murata, M" uniqKey="Murata M">M Murata</name></author><author><name sortKey="Tatsumi, J" uniqKey="Tatsumi J">J Tatsumi</name></author><author><name sortKey="Kato, Y" uniqKey="Kato Y">Y Kato</name></author><author><name sortKey="Suda, S" uniqKey="Suda S">S Suda</name></author><author><name sortKey="Nunokawa, Y" uniqKey="Nunokawa Y">Y Nunokawa</name></author><author><name sortKey="Kobayashi, Y" uniqKey="Kobayashi Y">Y Kobayashi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Melo, Rf" uniqKey="Melo R">RF Melo</name></author><author><name sortKey="Lopes, Bm" uniqKey="Lopes B">BM Lopes</name></author><author><name sortKey="Shibli, Ja" uniqKey="Shibli J">JA Shibli</name></author><author><name sortKey="Marcantonio, E" uniqKey="Marcantonio E">E Marcantonio</name></author><author><name sortKey="Marcantonio, Ra" uniqKey="Marcantonio R">RA Marcantonio</name></author><author><name sortKey="Galli, Gm" uniqKey="Galli G">GM Galli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stashenko, P" uniqKey="Stashenko P">P Stashenko</name></author><author><name sortKey="Dewhirst, Fe" uniqKey="Dewhirst F">FE Dewhirst</name></author><author><name sortKey="Peros, Wj" uniqKey="Peros W">WJ Peros</name></author><author><name sortKey="Kent, Rl" uniqKey="Kent R">RL Kent</name></author><author><name sortKey="Ago, Jm" uniqKey="Ago J">JM Ago</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Preiss, Ds" uniqKey="Preiss D">DS Preiss</name></author><author><name sortKey="Meyle, J" uniqKey="Meyle J">J Meyle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhong, Y" uniqKey="Zhong Y">Y Zhong</name></author><author><name sortKey="Slade, Gd" uniqKey="Slade G">GD Slade</name></author><author><name sortKey="Beck, Jd" uniqKey="Beck J">JD Beck</name></author><author><name sortKey="Offenbacher, S" uniqKey="Offenbacher S">S Offenbacher</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guncu, Gn" uniqKey="Guncu G">GN Güncü</name></author><author><name sortKey="Akman, Ac" uniqKey="Akman A">AC Akman</name></author><author><name sortKey="Gunday, S" uniqKey="Gunday S">S Günday</name></author><author><name sortKey="Yamal K, N" uniqKey="Yamal K N">N Yamalık</name></author><author><name sortKey="Berker, E" uniqKey="Berker E">E Berker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yaghobee, S" uniqKey="Yaghobee S">S Yaghobee</name></author><author><name sortKey="Khorsand, A" uniqKey="Khorsand A">A Khorsand</name></author><author><name sortKey="Paknejad, M" uniqKey="Paknejad M">M Paknejad</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liskmann, S" uniqKey="Liskmann S">S Liskmann</name></author><author><name sortKey="Vihalemm, T" uniqKey="Vihalemm T">T Vihalemm</name></author><author><name sortKey="Salum, O" uniqKey="Salum O">O Salum</name></author><author><name sortKey="Zilmer, K" uniqKey="Zilmer K">K Zilmer</name></author><author><name sortKey="Fischer, K" uniqKey="Fischer K">K Fischer</name></author><author><name sortKey="Zilmer, M" uniqKey="Zilmer M">M Zilmer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Konttinen, Yt" uniqKey="Konttinen Y">YT Konttinen</name></author><author><name sortKey="Lappalainen, R" uniqKey="Lappalainen R">R Lappalainen</name></author><author><name sortKey="Laine, P" uniqKey="Laine P">P Laine</name></author><author><name sortKey="Kitti, U" uniqKey="Kitti U">U Kitti</name></author><author><name sortKey="Santavirta, S" uniqKey="Santavirta S">S Santavirta</name></author><author><name sortKey="Teronen, O" uniqKey="Teronen O">O Teronen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mengel, R" uniqKey="Mengel R">R Mengel</name></author><author><name sortKey="Stelzel, M" uniqKey="Stelzel M">M Stelzel</name></author><author><name sortKey="Hasse, C" uniqKey="Hasse C">C Hasse</name></author><author><name sortKey="Flores De Jacoby, L" uniqKey="Flores De Jacoby L">L Flores-de-Jacoby</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Korean Assoc Oral Maxillofac Surg</journal-id><journal-id journal-id-type="iso-abbrev">J Korean Assoc Oral Maxillofac Surg</journal-id><journal-id journal-id-type="publisher-id">JKAOMS</journal-id><journal-title-group><journal-title>Journal of the Korean Association of Oral and Maxillofacial Surgeons</journal-title></journal-title-group><issn pub-type="ppub">2234-7550</issn><issn pub-type="epub">2234-5930</issn><publisher><publisher-name>The Korean Association of Oral and Maxillofacial Surgeons</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">25368834</article-id><article-id pub-id-type="pmc">4217267</article-id><article-id pub-id-type="doi">10.5125/jkaoms.2014.40.5.220</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject></subj-group></article-categories><title-group><article-title>Assessment of interleukin-1beta and interleukin-6 in the crevicular fluid around healthy implants, implants with peri-implantitis, and healthy teeth: a cross-sectional study</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Yaghobee</surname><given-names>Siamak</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Khorsand</surname><given-names>Afshin</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Rasouli Ghohroudi</surname><given-names>Amir Alireza</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Sanjari</surname><given-names>Khashayar</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Kadkhodazadeh</surname><given-names>Mahdi</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib></contrib-group><aff id="A1"><label>1</label>Department of Periodontics, Tehran University of Medical Sciences, Tehran, Iran.</aff><aff id="A2"><label>2</label>Dental Implant Research Center, Tehran University of Medical Sciences, Tehran, Iran.</aff><aff id="A3"><label>3</label>Private Practice, Tehran, Iran.</aff><aff id="A4"><label>4</label>Department of Periodontics, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.</aff><author-notes><corresp>Corresponding author: Mahdi Kadkhodazadeh. Department of Periodontics, Dental School, Shahid Beheshti University of Medical Sciences, Shahid Chamran Highway, Velenjak St., Tehran 1696813178, Iran. TEL: +98-9127608346, FAX: +98-2122190224, <email>kadkhodazadehmahdi@yahoo.com</email></corresp></author-notes><pub-date pub-type="ppub"><month>10</month><year>2014</year></pub-date><pub-date pub-type="epub"><day>24</day><month>10</month><year>2014</year></pub-date><volume>40</volume><issue>5</issue><fpage>220</fpage><lpage>224</lpage><history><date date-type="received"><day>04</day><month>6</month><year>2014</year></date><date date-type="rev-recd"><day>08</day><month>8</month><year>2014</year></date><date date-type="accepted"><day>27</day><month>8</month><year>2014</year></date></history><permissions><copyright-statement>Copyright © 2014 The Korean Association of Oral and Maxillofacial Surgeons. All rights reserved.</copyright-statement><copyright-year>2014</copyright-year><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc/3.0/"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by-nc/3.0/">http://creativecommons.org/licenses/by-nc/3.0/</ext-link>) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions><abstract><sec><title>Objectives</title><p>This study aimed to assess and compare the levels of interleukin-1beta (IL-1β) and interleukin-6 (IL-6) in the crevicular fluid around healthy implants, implants with peri-implantitis, and healthy teeth.</p></sec><sec><title>Materials and Methods</title><p>This study evaluated 16 dental implants in 8 patients (4 males and 4 females). These patients had at least one healthy implant and one implant with peri-implantitis next to healthy teeth. The crevicular fluid was collected using absorbent cones and transferred to the laboratory. Specimens were evaluated by ELISA for interleukin levels. Data were analyzed using repeated measures ANOVA and Bonferroni tests (<italic>P</italic><0.05).</p></sec><sec><title>Results</title><p>Levels of IL-1β in the crevicular fluid around implants with peri-implantitis were significantly higher than around healthy implants (<italic>P</italic>=0.002); the latter was significantly higher than around healthy teeth (<italic>P</italic>=0.015). A significant difference was found in the level of IL-6 in the crevicular fluid around implants with peri-implantitis and healthy implants (<italic>P</italic>=0.049) and also between implants with peri-implantitis and healthy teeth (<italic>P</italic><0.001).</p></sec><sec><title>Conclusion</title><p>Within the limitations of this study, significant differences exist in the levels of IL-1β and IL-6 in the crevicular fluid of implants with peri-implantitis, healthy implants, and healthy teeth. More studies with larger sample sizes in different populations are necessary.</p></sec></abstract><kwd-group><kwd>Dental implants</kwd><kwd>Peri-implantitis</kwd><kwd>Interleukin-1beta</kwd><kwd>Interleukin-6</kwd><kwd>Gingival crevicular fluid</kwd></kwd-group></article-meta></front><floats-group><table-wrap id="T1" orientation="portrait" position="float"><label>Table 1</label><caption><p>Comparison of the level of interleukin-6 (IL-6) among the three groups</p></caption><graphic xlink:href="jkaoms-40-220-i001"></graphic></table-wrap><table-wrap id="T2" orientation="portrait" position="float"><label>Table 2</label><caption><p>Comparison of the level of interleukin-1beta (IL-1β) amongthe three groups</p></caption><graphic xlink:href="jkaoms-40-220-i002"></graphic></table-wrap></floats-group></pmc><affiliations><list><country><li>Iran</li></country></list><tree><country name="Iran"><noRegion><name sortKey="Yaghobee, Siamak" sort="Yaghobee, Siamak" uniqKey="Yaghobee S" first="Siamak" last="Yaghobee">Siamak Yaghobee</name></noRegion><name sortKey="Kadkhodazadeh, Mahdi" sort="Kadkhodazadeh, Mahdi" uniqKey="Kadkhodazadeh M" first="Mahdi" last="Kadkhodazadeh">Mahdi Kadkhodazadeh</name><name sortKey="Khorsand, Afshin" sort="Khorsand, Afshin" uniqKey="Khorsand A" first="Afshin" last="Khorsand">Afshin Khorsand</name><name sortKey="Rasouli Ghohroudi, Amir Alireza" sort="Rasouli Ghohroudi, Amir Alireza" uniqKey="Rasouli Ghohroudi A" first="Amir Alireza" last="Rasouli Ghohroudi">Amir Alireza Rasouli Ghohroudi</name><name sortKey="Sanjari, Khashayar" sort="Sanjari, Khashayar" uniqKey="Sanjari K" first="Khashayar" last="Sanjari">Khashayar Sanjari</name><name sortKey="Yaghobee, Siamak" sort="Yaghobee, Siamak" uniqKey="Yaghobee S" first="Siamak" last="Yaghobee">Siamak Yaghobee</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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