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The use of fresh-frozen bone in oral surgery: a clinical study of 14 consecutive cases

Identifieur interne : 003396 ( Ncbi/Merge ); précédent : 003395; suivant : 003397

The use of fresh-frozen bone in oral surgery: a clinical study of 14 consecutive cases

Auteurs : Chiara D Loja ; Ernesto D Loja [Italie] ; Enrico Santi [Italie] ; Massimo Franchini

Source :

Blood Transfusion [ 1723-2007 ] ; 2011.

RBID : PMC:3021396

Abstract

Background

Although autologous bone is considered the gold standard among the grafting materials used in implant therapy, it does have a number of drawbacks, in particular morbidity at the site of donation and the limited amount of bone available. To overcome these limitations a number of alternative bone materials have been employed in the last few years. In this study we report the results of the use of homologous fresh-frozen bone from a tissue bank in patients undergoing reconstruction of bone defects in the oral cavity.

Material and methods

Between June 2004 and October 2008, 14 consecutive patients underwent bone reconstruction with fresh-frozen bone from a tissue bank. Four to eight months after surgery, implants were placed in the newly formed bone.

Results

No problems were recorded during the post-operative course. In all cases treatment was successful and osteointegrated implants were placed in the newly formed bone after 4–8 months. All implants showed good osteointegration (100% overall success rate, mean follow-up 20 months), allowing loading with a fixed cemented prosthesis.

Conclusions

Our results support the previous findings that homologous fresh-frozen bone can be considered a valid alternative to autologous bone for the reconstruction of bone defects in the oral cavity in patients undergoing implant therapy.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021396

DOI: 10.2450/2010.0130-09
PubMed: 21235853
PubMed Central: 3021396

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PMC:3021396

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<front><div type="abstract" xml:lang="en"><sec><title>Background</title>
<p>Although autologous bone is considered the gold standard among the grafting materials used in implant therapy, it does have a number of drawbacks, in particular morbidity at the site of donation and the limited amount of bone available. To overcome these limitations a number of alternative bone materials have been employed in the last few years. In this study we report the results of the use of homologous fresh-frozen bone from a tissue bank in patients undergoing reconstruction of bone defects in the oral cavity.</p>
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<sec><title>Material and methods</title>
<p>Between June 2004 and October 2008, 14 consecutive patients underwent bone reconstruction with fresh-frozen bone from a tissue bank. Four to eight months after surgery, implants were placed in the newly formed bone.</p>
</sec>
<sec><title>Results</title>
<p>No problems were recorded during the post-operative course. In all cases treatment was successful and osteointegrated implants were placed in the newly formed bone after 4–8 months. All implants showed good osteointegration (100% overall success rate, mean follow-up 20 months), allowing loading with a fixed cemented prosthesis.</p>
</sec>
<sec><title>Conclusions</title>
<p>Our results support the previous findings that homologous fresh-frozen bone can be considered a valid alternative to autologous bone for the reconstruction of bone defects in the oral cavity in patients undergoing implant therapy.</p>
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<title-group><article-title>The use of fresh-frozen bone in oral surgery: a clinical study of 14 consecutive cases</article-title>
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<contrib-group><contrib contrib-type="author"><name><surname>D’Aloja</surname>
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 Service of Immunohaematology and Transfusion Medicine, Department of Pathology and Laboratory Medicine, University Hospital of Parma, Parma</aff>
<aff id="af2-blt-09-041"><label>2</label>
 Clinical Offices, Negrar, Verona, Italy</aff>
<author-notes><corresp id="c1-blt-09-041">Correspondence: Chiara D’Aloja, Servizio di Immunoematologia e Medicina Trasfusionale, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero-Universitaria di Parma, Via Gramsci 14, 43100 Parma Italy, e-mail: <email>chiara_daloja@hotmail.it</email>
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<pub-date pub-type="ppub"><month>1</month>
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<volume>9</volume>
<issue>1</issue>
<fpage>41</fpage>
<lpage>45</lpage>
<history><date date-type="received"><day>29</day>
<month>4</month>
<year>2009</year>
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<date date-type="accepted"><day>29</day>
<month>9</month>
<year>2010</year>
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<permissions><copyright-statement>© SIMTI Servizi Srl</copyright-statement>
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<abstract><sec><title>Background</title>
<p>Although autologous bone is considered the gold standard among the grafting materials used in implant therapy, it does have a number of drawbacks, in particular morbidity at the site of donation and the limited amount of bone available. To overcome these limitations a number of alternative bone materials have been employed in the last few years. In this study we report the results of the use of homologous fresh-frozen bone from a tissue bank in patients undergoing reconstruction of bone defects in the oral cavity.</p>
</sec>
<sec><title>Material and methods</title>
<p>Between June 2004 and October 2008, 14 consecutive patients underwent bone reconstruction with fresh-frozen bone from a tissue bank. Four to eight months after surgery, implants were placed in the newly formed bone.</p>
</sec>
<sec><title>Results</title>
<p>No problems were recorded during the post-operative course. In all cases treatment was successful and osteointegrated implants were placed in the newly formed bone after 4–8 months. All implants showed good osteointegration (100% overall success rate, mean follow-up 20 months), allowing loading with a fixed cemented prosthesis.</p>
</sec>
<sec><title>Conclusions</title>
<p>Our results support the previous findings that homologous fresh-frozen bone can be considered a valid alternative to autologous bone for the reconstruction of bone defects in the oral cavity in patients undergoing implant therapy.</p>
</sec>
</abstract>
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The use of fresh-frozen bone in oral surgery: a clinical study of 14 consecutive cases

The use of fresh-frozen bone in oral surgery: a clinical study of 14 consecutive cases

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