Impact of Human Genome Project on treatment of frail and edentulous patients.
Identifieur interne : 001304 ( Ncbi/Merge ); précédent : 001303; suivant : 001305Impact of Human Genome Project on treatment of frail and edentulous patients.
Auteurs : Ichiro Nishimura [États-Unis] ; Neal GarrettSource :
- Gerodontology [ 0734-0664 ] ; 2004.
Descripteurs français
- KwdFr :
- Appariement de bases (génétique), Humains, Mandibule (anatomopathologie), Mastication (physiologie), Mâchoire édentée (génétique), Mâchoire édentée (rééducation et réadaptation), Overdenture, Personne âgée fragile, Planification des soins du patient, Polymorphisme de nucléotide simple (génétique), Projet génome humain, Prothèse dentaire complète, Prothèse dentaire implanto-portée, Résorption osseuse (génétique), Satisfaction du patient, Soins dentaires pour personnes âgées, Sujet âgé.
- MESH :
- anatomopathologie : Mandibule.
- génétique : Appariement de bases, Mâchoire édentée, Polymorphisme de nucléotide simple, Résorption osseuse.
- physiologie : Mastication.
- rééducation et réadaptation : Mâchoire édentée.
- Humains, Overdenture, Personne âgée fragile, Planification des soins du patient, Projet génome humain, Prothèse dentaire complète, Prothèse dentaire implanto-portée, Satisfaction du patient, Soins dentaires pour personnes âgées, Sujet âgé.
English descriptors
- KwdEn :
- Aged, Base Pairing (genetics), Bone Resorption (genetics), Dental Care for Aged, Dental Prosthesis, Implant-Supported, Denture, Complete, Denture, Overlay, Frail Elderly, Human Genome Project, Humans, Jaw, Edentulous (genetics), Jaw, Edentulous (rehabilitation), Mandible (pathology), Mastication (physiology), Patient Care Planning, Patient Satisfaction, Polymorphism, Single Nucleotide (genetics).
- MESH :
- genetics : Base Pairing, Bone Resorption, Jaw, Edentulous, Polymorphism, Single Nucleotide.
- pathology : Mandible.
- physiology : Mastication.
- rehabilitation : Jaw, Edentulous.
- Aged, Dental Care for Aged, Dental Prosthesis, Implant-Supported, Denture, Complete, Denture, Overlay, Frail Elderly, Human Genome Project, Humans, Patient Care Planning, Patient Satisfaction.
Abstract
Because of ongoing increases in life expectancy and deferment of edentulousness to older age, dentists are facing a different challenge to satisfy elderly denture wearers with a higher prevalence of chronic diseases. This discussion introduces the Human Genome databases as novel and powerful resources to re-examine the core problems experienced by frail and edentulous patients.
PubMed: 15074534
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pubmed:15074534Le document en format XML
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<affiliation wicri:level="1"><nlm:affiliation>The Weintraub Center for Reconstructive Biotechnology, Division of Advanced Prosthodontics, Biomaterials and Hospital Dentistry, UCLA School of Dentistry, Los Angeles, CA 90095, USA. ichiron@dent.ucla.edu</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Base Pairing (genetics)</term>
<term>Bone Resorption (genetics)</term>
<term>Dental Care for Aged</term>
<term>Dental Prosthesis, Implant-Supported</term>
<term>Denture, Complete</term>
<term>Denture, Overlay</term>
<term>Frail Elderly</term>
<term>Human Genome Project</term>
<term>Humans</term>
<term>Jaw, Edentulous (genetics)</term>
<term>Jaw, Edentulous (rehabilitation)</term>
<term>Mandible (pathology)</term>
<term>Mastication (physiology)</term>
<term>Patient Care Planning</term>
<term>Patient Satisfaction</term>
<term>Polymorphism, Single Nucleotide (genetics)</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Appariement de bases (génétique)</term>
<term>Humains</term>
<term>Mandibule (anatomopathologie)</term>
<term>Mastication (physiologie)</term>
<term>Mâchoire édentée (génétique)</term>
<term>Mâchoire édentée (rééducation et réadaptation)</term>
<term>Overdenture</term>
<term>Personne âgée fragile</term>
<term>Planification des soins du patient</term>
<term>Polymorphisme de nucléotide simple (génétique)</term>
<term>Projet génome humain</term>
<term>Prothèse dentaire complète</term>
<term>Prothèse dentaire implanto-portée</term>
<term>Résorption osseuse (génétique)</term>
<term>Satisfaction du patient</term>
<term>Soins dentaires pour personnes âgées</term>
<term>Sujet âgé</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Mandibule</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Base Pairing</term>
<term>Bone Resorption</term>
<term>Jaw, Edentulous</term>
<term>Polymorphism, Single Nucleotide</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Appariement de bases</term>
<term>Mâchoire édentée</term>
<term>Polymorphisme de nucléotide simple</term>
<term>Résorption osseuse</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Mandible</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Mastication</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Mastication</term>
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<keywords scheme="MESH" qualifier="rehabilitation" xml:lang="en"><term>Jaw, Edentulous</term>
</keywords>
<keywords scheme="MESH" qualifier="rééducation et réadaptation" xml:lang="fr"><term>Mâchoire édentée</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Dental Care for Aged</term>
<term>Dental Prosthesis, Implant-Supported</term>
<term>Denture, Complete</term>
<term>Denture, Overlay</term>
<term>Frail Elderly</term>
<term>Human Genome Project</term>
<term>Humans</term>
<term>Patient Care Planning</term>
<term>Patient Satisfaction</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Humains</term>
<term>Overdenture</term>
<term>Personne âgée fragile</term>
<term>Planification des soins du patient</term>
<term>Projet génome humain</term>
<term>Prothèse dentaire complète</term>
<term>Prothèse dentaire implanto-portée</term>
<term>Satisfaction du patient</term>
<term>Soins dentaires pour personnes âgées</term>
<term>Sujet âgé</term>
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<front><div type="abstract" xml:lang="en">Because of ongoing increases in life expectancy and deferment of edentulousness to older age, dentists are facing a different challenge to satisfy elderly denture wearers with a higher prevalence of chronic diseases. This discussion introduces the Human Genome databases as novel and powerful resources to re-examine the core problems experienced by frail and edentulous patients.</div>
</front>
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<DateCompleted><Year>2004</Year>
<Month>05</Month>
<Day>04</Day>
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<DateRevised><Year>2006</Year>
<Month>11</Month>
<Day>15</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0734-0664</ISSN>
<JournalIssue CitedMedium="Print"><Volume>21</Volume>
<Issue>1</Issue>
<PubDate><Year>2004</Year>
<Month>Mar</Month>
</PubDate>
</JournalIssue>
<Title>Gerodontology</Title>
<ISOAbbreviation>Gerodontology</ISOAbbreviation>
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<ArticleTitle>Impact of Human Genome Project on treatment of frail and edentulous patients.</ArticleTitle>
<Pagination><MedlinePgn>3-9</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">Because of ongoing increases in life expectancy and deferment of edentulousness to older age, dentists are facing a different challenge to satisfy elderly denture wearers with a higher prevalence of chronic diseases. This discussion introduces the Human Genome databases as novel and powerful resources to re-examine the core problems experienced by frail and edentulous patients.</AbstractText>
<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Recent studies demonstrated that mandibular implant overdentures do not necessarily increase masticatory function, perception and satisfaction in denture wearers with adequate edentulous residual ridges. It has been demonstrated that the rate of edentulous residual ridge resorption significantly varies among individuals. The prognosis and cost-effectiveness of denture treatment, with or without implants, may largely depend on how the edentulous ridge is maintained. However, reliable clinical methods permitting dentists to predict the long-term health of the edentulous residual ridge are lacking.</AbstractText>
<AbstractText Label="MATERIALS AND METHODS" NlmCategory="METHODS">With the completion of the Human Genome Project, the genomic sequence database from this multinational consortium will provide a unique resource to determine the genetic basis of similarity and diversity of humans.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">One base pair in every 100 to 300 base pairs of the genome sequence varies among humans, suggesting that genetic diagnosis using the single nucleotide polymorphisms (SNPs) may provide a novel opportunity to differentiate our edentulous patients.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Future dental service for the elderly will require a personalized care paradigm, using highly sensitive diagnostic technology such as SNP genomic analysis, for recommending the treatment with greatest potential benefit.</AbstractText>
</Abstract>
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<AffiliationInfo><Affiliation>The Weintraub Center for Reconstructive Biotechnology, Division of Advanced Prosthodontics, Biomaterials and Hospital Dentistry, UCLA School of Dentistry, Los Angeles, CA 90095, USA. ichiron@dent.ucla.edu</Affiliation>
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<MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
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<MeshHeading><DescriptorName UI="D020029" MajorTopicYN="N">Base Pairing</DescriptorName>
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<MeshHeading><DescriptorName UI="D019094" MajorTopicYN="N">Dental Prosthesis, Implant-Supported</DescriptorName>
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<MeshHeading><DescriptorName UI="D003824" MajorTopicYN="N">Denture, Complete</DescriptorName>
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<MeshHeading><DescriptorName UI="D003828" MajorTopicYN="N">Denture, Overlay</DescriptorName>
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<MeshHeading><DescriptorName UI="D016330" MajorTopicYN="Y">Frail Elderly</DescriptorName>
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<MeshHeading><DescriptorName UI="D016045" MajorTopicYN="Y">Human Genome Project</DescriptorName>
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<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
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<MeshHeading><DescriptorName UI="D007575" MajorTopicYN="N">Jaw, Edentulous</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000534" MajorTopicYN="Y">rehabilitation</QualifierName>
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<MeshHeading><DescriptorName UI="D008334" MajorTopicYN="N">Mandible</DescriptorName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
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<MeshHeading><DescriptorName UI="D008409" MajorTopicYN="N">Mastication</DescriptorName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
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<MeshHeading><DescriptorName UI="D010347" MajorTopicYN="N">Patient Care Planning</DescriptorName>
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<MeshHeading><DescriptorName UI="D017060" MajorTopicYN="N">Patient Satisfaction</DescriptorName>
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<MeshHeading><DescriptorName UI="D020641" MajorTopicYN="N">Polymorphism, Single Nucleotide</DescriptorName>
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