Expression of endothelial adhesion molecules in the alveolar ridge mucosa, gingiva and periimplant mucosa.
Identifieur interne : 000A33 ( Ncbi/Merge ); précédent : 000A32; suivant : 000A34Expression of endothelial adhesion molecules in the alveolar ridge mucosa, gingiva and periimplant mucosa.
Auteurs : N U Zitzmann [Suisse] ; T. Berglundh ; C P Marinello ; J. LindheSource :
- Journal of clinical periodontology [ 0303-6979 ] ; 2002.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Analyse appariée, Anticorps monoclonaux, Attache épithéliale (anatomopathologie), Cellules épithéliales (anatomopathologie), Endothélium vasculaire (anatomopathologie), Endothélium vasculaire (métabolisme), Femelle, Gencive (), Gencive (métabolisme), Gingivite (anatomopathologie), Humains, Immunohistochimie, Implants dentaires, Kératines, Leucocytes (anatomopathologie), Molécule-1 d'adhérence des cellules vasculaires (analyse), Molécule-1 d'adhérence intercellulaire (analyse), Muqueuse de la bouche (), Muqueuse de la bouche (métabolisme), Mâchoire partiellement édentée (anatomopathologie), Mâle, Plaque dentaire (microbiologie), Processus alvéolaire (anatomopathologie), Processus alvéolaire (métabolisme), Statistiques comme sujet, Sujet âgé, Sélectine E (analyse), Tissu conjonctif (anatomopathologie).
- MESH :
- analyse : Molécule-1 d'adhérence des cellules vasculaires, Molécule-1 d'adhérence intercellulaire, Sélectine E.
- anatomopathologie : Attache épithéliale, Cellules épithéliales, Endothélium vasculaire, Gingivite, Leucocytes, Mâchoire partiellement édentée, Processus alvéolaire, Tissu conjonctif.
- microbiologie : Plaque dentaire.
- métabolisme : Endothélium vasculaire, Gencive, Muqueuse de la bouche, Processus alvéolaire.
- Adulte d'âge moyen, Analyse appariée, Anticorps monoclonaux, Femelle, Gencive, Humains, Immunohistochimie, Implants dentaires, Kératines, Muqueuse de la bouche, Mâle, Statistiques comme sujet, Sujet âgé.
English descriptors
- KwdEn :
- Aged, Alveolar Process (metabolism), Alveolar Process (pathology), Antibodies, Monoclonal, Connective Tissue (pathology), Dental Implants, Dental Plaque (microbiology), E-Selectin (analysis), Endothelium, Vascular (metabolism), Endothelium, Vascular (pathology), Epithelial Attachment (pathology), Epithelial Cells (pathology), Female, Gingiva (blood supply), Gingiva (metabolism), Gingivitis (pathology), Humans, Immunohistochemistry, Intercellular Adhesion Molecule-1 (analysis), Jaw, Edentulous, Partially (pathology), Keratins, Leukocytes (pathology), Male, Matched-Pair Analysis, Middle Aged, Mouth Mucosa (blood supply), Mouth Mucosa (metabolism), Statistics as Topic, Vascular Cell Adhesion Molecule-1 (analysis).
- MESH :
- chemical , analysis : E-Selectin, Intercellular Adhesion Molecule-1, Vascular Cell Adhesion Molecule-1.
- chemical : Antibodies, Monoclonal, Dental Implants, Keratins.
- blood supply : Gingiva, Mouth Mucosa.
- metabolism : Alveolar Process, Endothelium, Vascular, Gingiva, Mouth Mucosa.
- microbiology : Dental Plaque.
- pathology : Alveolar Process, Connective Tissue, Endothelium, Vascular, Epithelial Attachment, Epithelial Cells, Gingivitis, Jaw, Edentulous, Partially, Leukocytes.
- Aged, Female, Humans, Immunohistochemistry, Male, Matched-Pair Analysis, Middle Aged, Statistics as Topic.
Abstract
The purpose of this study was to analyze the expression of adhesion molecules on endothelial cells in the alveolar ridge mucosa, the gingiva and the periimplant mucosa in humans.
PubMed: 12296774
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 003193
- to stream PubMed, to step Curation: 003193
- to stream PubMed, to step Checkpoint: 003193
Links to Exploration step
pubmed:12296774Le document en format XML
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<term>Alveolar Process (metabolism)</term>
<term>Alveolar Process (pathology)</term>
<term>Antibodies, Monoclonal</term>
<term>Connective Tissue (pathology)</term>
<term>Dental Implants</term>
<term>Dental Plaque (microbiology)</term>
<term>E-Selectin (analysis)</term>
<term>Endothelium, Vascular (metabolism)</term>
<term>Endothelium, Vascular (pathology)</term>
<term>Epithelial Attachment (pathology)</term>
<term>Epithelial Cells (pathology)</term>
<term>Female</term>
<term>Gingiva (blood supply)</term>
<term>Gingiva (metabolism)</term>
<term>Gingivitis (pathology)</term>
<term>Humans</term>
<term>Immunohistochemistry</term>
<term>Intercellular Adhesion Molecule-1 (analysis)</term>
<term>Jaw, Edentulous, Partially (pathology)</term>
<term>Keratins</term>
<term>Leukocytes (pathology)</term>
<term>Male</term>
<term>Matched-Pair Analysis</term>
<term>Middle Aged</term>
<term>Mouth Mucosa (blood supply)</term>
<term>Mouth Mucosa (metabolism)</term>
<term>Statistics as Topic</term>
<term>Vascular Cell Adhesion Molecule-1 (analysis)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Analyse appariée</term>
<term>Anticorps monoclonaux</term>
<term>Attache épithéliale (anatomopathologie)</term>
<term>Cellules épithéliales (anatomopathologie)</term>
<term>Endothélium vasculaire (anatomopathologie)</term>
<term>Endothélium vasculaire (métabolisme)</term>
<term>Femelle</term>
<term>Gencive ()</term>
<term>Gencive (métabolisme)</term>
<term>Gingivite (anatomopathologie)</term>
<term>Humains</term>
<term>Immunohistochimie</term>
<term>Implants dentaires</term>
<term>Kératines</term>
<term>Leucocytes (anatomopathologie)</term>
<term>Molécule-1 d'adhérence des cellules vasculaires (analyse)</term>
<term>Molécule-1 d'adhérence intercellulaire (analyse)</term>
<term>Muqueuse de la bouche ()</term>
<term>Muqueuse de la bouche (métabolisme)</term>
<term>Mâchoire partiellement édentée (anatomopathologie)</term>
<term>Mâle</term>
<term>Plaque dentaire (microbiologie)</term>
<term>Processus alvéolaire (anatomopathologie)</term>
<term>Processus alvéolaire (métabolisme)</term>
<term>Statistiques comme sujet</term>
<term>Sujet âgé</term>
<term>Sélectine E (analyse)</term>
<term>Tissu conjonctif (anatomopathologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>E-Selectin</term>
<term>Intercellular Adhesion Molecule-1</term>
<term>Vascular Cell Adhesion Molecule-1</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Antibodies, Monoclonal</term>
<term>Dental Implants</term>
<term>Keratins</term>
</keywords>
<keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>Molécule-1 d'adhérence des cellules vasculaires</term>
<term>Molécule-1 d'adhérence intercellulaire</term>
<term>Sélectine E</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Attache épithéliale</term>
<term>Cellules épithéliales</term>
<term>Endothélium vasculaire</term>
<term>Gingivite</term>
<term>Leucocytes</term>
<term>Mâchoire partiellement édentée</term>
<term>Processus alvéolaire</term>
<term>Tissu conjonctif</term>
</keywords>
<keywords scheme="MESH" qualifier="blood supply" xml:lang="en"><term>Gingiva</term>
<term>Mouth Mucosa</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Alveolar Process</term>
<term>Endothelium, Vascular</term>
<term>Gingiva</term>
<term>Mouth Mucosa</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiologie" xml:lang="fr"><term>Plaque dentaire</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Dental Plaque</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Endothélium vasculaire</term>
<term>Gencive</term>
<term>Muqueuse de la bouche</term>
<term>Processus alvéolaire</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Alveolar Process</term>
<term>Connective Tissue</term>
<term>Endothelium, Vascular</term>
<term>Epithelial Attachment</term>
<term>Epithelial Cells</term>
<term>Gingivitis</term>
<term>Jaw, Edentulous, Partially</term>
<term>Leukocytes</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Female</term>
<term>Humans</term>
<term>Immunohistochemistry</term>
<term>Male</term>
<term>Matched-Pair Analysis</term>
<term>Middle Aged</term>
<term>Statistics as Topic</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Analyse appariée</term>
<term>Anticorps monoclonaux</term>
<term>Femelle</term>
<term>Gencive</term>
<term>Humains</term>
<term>Immunohistochimie</term>
<term>Implants dentaires</term>
<term>Kératines</term>
<term>Muqueuse de la bouche</term>
<term>Mâle</term>
<term>Statistiques comme sujet</term>
<term>Sujet âgé</term>
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<front><div type="abstract" xml:lang="en">The purpose of this study was to analyze the expression of adhesion molecules on endothelial cells in the alveolar ridge mucosa, the gingiva and the periimplant mucosa in humans.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">12296774</PMID>
<DateCompleted><Year>2002</Year>
<Month>12</Month>
<Day>19</Day>
</DateCompleted>
<DateRevised><Year>2015</Year>
<Month>11</Month>
<Day>19</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0303-6979</ISSN>
<JournalIssue CitedMedium="Print"><Volume>29</Volume>
<Issue>6</Issue>
<PubDate><Year>2002</Year>
<Month>Jun</Month>
</PubDate>
</JournalIssue>
<Title>Journal of clinical periodontology</Title>
<ISOAbbreviation>J. Clin. Periodontol.</ISOAbbreviation>
</Journal>
<ArticleTitle>Expression of endothelial adhesion molecules in the alveolar ridge mucosa, gingiva and periimplant mucosa.</ArticleTitle>
<Pagination><MedlinePgn>490-5</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">The purpose of this study was to analyze the expression of adhesion molecules on endothelial cells in the alveolar ridge mucosa, the gingiva and the periimplant mucosa in humans.</AbstractText>
<AbstractText Label="MATERIAL AND METHODS" NlmCategory="METHODS">Twelve partially edentulous subjects were included in the study. In each subject, one soft tissue biopsy was harvested from the edentulous alveolar ridge mucosa, one from a tooth site and one from an implant site. After 3 weeks of undisturbed plaque accumulation, an additional biopsy was obtained from one tooth and one implant site in each subject. The tissue samples were snap frozen and prepared for immunohistochemical analysis.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">In the alveolar ridge mucosa, smaller proportions of endothelial cells expressing ICAM-1, ELAM-1 and VCAM-1 were observed than in the gingiva. ELAM-1-positive cells occurred in lower numbers than in periimplant mucosa. After 21 days of plaque accumulation, ELAM-1 was increased in tooth sites, but decreased in periimplant mucosa.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The results of the present study indicated that the proportions of activated endothelial cells and the extravasation of leukocytes is larger in gingiva and periimplant mucosa than in alveolar ridge mucosa. This might be due to the less permeable keratinized epithelial layer in the edentulous ridge mucosa, which offers proper protection against microbial pathogens. The greater expression of endothelial cell adhesion molecules during experimental gingivitis, compared to periimplant mucositis, may reflect its longer history of repeated antigenic assaults.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Zitzmann</LastName>
<ForeName>N U</ForeName>
<Initials>NU</Initials>
<AffiliationInfo><Affiliation>Clinic of Fixed and Removable Prosthodontics and TMJ Disorders, University of Basel, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Berglundh</LastName>
<ForeName>T</ForeName>
<Initials>T</Initials>
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<Author ValidYN="Y"><LastName>Marinello</LastName>
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<Author ValidYN="Y"><LastName>Lindhe</LastName>
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<ISSNLinking>0303-6979</ISSNLinking>
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<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D000911">Antibodies, Monoclonal</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D015921">Dental Implants</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D019040">E-Selectin</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D019010">Vascular Cell Adhesion Molecule-1</NameOfSubstance>
</Chemical>
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<Chemical><RegistryNumber>68238-35-7</RegistryNumber>
<NameOfSubstance UI="D007633">Keratins</NameOfSubstance>
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<CitationSubset>D</CitationSubset>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000539" MajorTopicYN="N">Alveolar Process</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
<QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000911" MajorTopicYN="N">Antibodies, Monoclonal</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003238" MajorTopicYN="N">Connective Tissue</DescriptorName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015921" MajorTopicYN="Y">Dental Implants</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003773" MajorTopicYN="N">Dental Plaque</DescriptorName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D019040" MajorTopicYN="N">E-Selectin</DescriptorName>
<QualifierName UI="Q000032" MajorTopicYN="Y">analysis</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004730" MajorTopicYN="N">Endothelium, Vascular</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
<QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004846" MajorTopicYN="N">Epithelial Attachment</DescriptorName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
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<MeshHeading><DescriptorName UI="D004847" MajorTopicYN="N">Epithelial Cells</DescriptorName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005881" MajorTopicYN="N">Gingiva</DescriptorName>
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</MeshHeading>
<MeshHeading><DescriptorName UI="D007150" MajorTopicYN="N">Immunohistochemistry</DescriptorName>
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<QualifierName UI="Q000032" MajorTopicYN="Y">analysis</QualifierName>
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<MeshHeading><DescriptorName UI="D007576" MajorTopicYN="N">Jaw, Edentulous, Partially</DescriptorName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007633" MajorTopicYN="N">Keratins</DescriptorName>
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<MeshHeading><DescriptorName UI="D007962" MajorTopicYN="N">Leukocytes</DescriptorName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016555" MajorTopicYN="N">Matched-Pair Analysis</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009061" MajorTopicYN="N">Mouth Mucosa</DescriptorName>
<QualifierName UI="Q000098" MajorTopicYN="Y">blood supply</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013223" MajorTopicYN="N">Statistics as Topic</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D019010" MajorTopicYN="N">Vascular Cell Adhesion Molecule-1</DescriptorName>
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