Evaluation of bone morphogenic proteins in periodontal practice
Identifieur interne : 006668 ( Ncbi/Curation ); précédent : 006667; suivant : 006669Evaluation of bone morphogenic proteins in periodontal practice
Auteurs : Supreet Kaur ; Vishakha Grover ; Harkiran Kaur ; Ranjan MalhotraSource :
- Indian Journal of Dentistry [ 0975-962X ] ; 2016.
Abstract
Forty years ago Marshal R. Urist discovered a substance in bone matrix that had inductive properties for the development of bone and cartilage, until date, at least 20 bone morphogenetic proteins (BMPs) have been identified, some of which have been shown
Url:
DOI: 10.4103/0975-962X.179379
PubMed: 27134452
PubMed Central: 4836095
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Evaluation of bone morphogenic proteins in periodontal practice</title>
<author><name sortKey="Kaur, Supreet" sort="Kaur, Supreet" uniqKey="Kaur S" first="Supreet" last="Kaur">Supreet Kaur</name>
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<author><name sortKey="Grover, Vishakha" sort="Grover, Vishakha" uniqKey="Grover V" first="Vishakha" last="Grover">Vishakha Grover</name>
<affiliation><nlm:aff id="aff2"><italic>Department of Periodontics, National Dental College and Hospital, Dera Bassi, Punjab, India</italic>
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<author><name sortKey="Kaur, Harkiran" sort="Kaur, Harkiran" uniqKey="Kaur H" first="Harkiran" last="Kaur">Harkiran Kaur</name>
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<author><name sortKey="Malhotra, Ranjan" sort="Malhotra, Ranjan" uniqKey="Malhotra R" first="Ranjan" last="Malhotra">Ranjan Malhotra</name>
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<series><title level="j">Indian Journal of Dentistry</title>
<idno type="ISSN">0975-962X</idno>
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<front><div type="abstract" xml:lang="en"><p>Forty years ago Marshal R. Urist discovered a substance in bone matrix that had inductive properties for the development of bone and cartilage, until date, at least 20 bone morphogenetic proteins (BMPs) have been identified, some of which have been shown <italic>in vitro</italic>
to stimulate the process of stem cell differentiation into osteoblasts in human and animal models. The purpose of this paper is to give a brief overview of BMPs and to review critically the clinical data currently available on the use of BMPs in various periodontal applications. The literature on BMPs was reviewed. A comprehensive search was designed. The articles were independently screened for eligibility. Articles with authentic controls and proper randomization and pertaining specifically to their role in periodontal applications were included. The available literature was analyzed and compiled. The analysis indicates BMPs to be a promising, as well as an effective novel approach to reconstruct and engineer the periodontal apparatus. Here, we represent several articles, as well as recent texts that make up a special and an in-depth review on the subject. On the basis of the data provided in the studies that were reviewed BMPs provide revolutionary therapies in periodontal practice.</p>
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