Oral squamous cell carcinoma in a patient treated with long-term pegylated liposomal doxorubicin for recurrent ovarian cancer
Identifieur interne : 005783 ( Ncbi/Curation ); précédent : 005782; suivant : 005784Oral squamous cell carcinoma in a patient treated with long-term pegylated liposomal doxorubicin for recurrent ovarian cancer
Auteurs : Matteo Pezzoli ; Maurizio Bona Galvagno ; Guido BongioanniniSource :
- BMJ Case Reports [ 1757-790X ] ; 2015.
Abstract
We present a case of a woman who developed an oral squamous cell carcinoma (SCC) after being treated for a recurrent ovarian carcinoma with subtotal gastric resection and adjuvant pegylated liposomal doxorubicin (PLD). She received six cycles of PLD induction and maintenance therapy, which was continued for 5 years. She was free from disease at the following visits but 3 years later she developed SCC of her left inferior edentulous gums. The patient was negative for human papillomavirus and had never smoked in her life or had a history of alcohol use or any other environmental risk factors. PLD is known to accumulate in eccrine glands of the hands and the feet and in the oral mucosa, therefore causing skin toxicity and mucositis. It is conceivable that this specific biodistribution to the oral mucosa may be responsible for the onset of SCC.
Url:
DOI: 10.1136/bcr-2014-204056
PubMed: 25589526
PubMed Central: 4307081
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001A26
- to stream Pmc, to step Curation: Pour aller vers cette notice dans l'étape Curation :001A26
- to stream Pmc, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000C03
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :005783
Links to Exploration step
PMC:4307081Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Oral squamous cell carcinoma in a patient treated with long-term pegylated liposomal doxorubicin for recurrent ovarian cancer</title>
<author><name sortKey="Pezzoli, Matteo" sort="Pezzoli, Matteo" uniqKey="Pezzoli M" first="Matteo" last="Pezzoli">Matteo Pezzoli</name>
</author>
<author><name sortKey="Bona Galvagno, Maurizio" sort="Bona Galvagno, Maurizio" uniqKey="Bona Galvagno M" first="Maurizio" last="Bona Galvagno">Maurizio Bona Galvagno</name>
</author>
<author><name sortKey="Bongioannini, Guido" sort="Bongioannini, Guido" uniqKey="Bongioannini G" first="Guido" last="Bongioannini">Guido Bongioannini</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">25589526</idno>
<idno type="pmc">4307081</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307081</idno>
<idno type="RBID">PMC:4307081</idno>
<idno type="doi">10.1136/bcr-2014-204056</idno>
<date when="2015">2015</date>
<idno type="wicri:Area/Pmc/Corpus">001A26</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001A26</idno>
<idno type="wicri:Area/Pmc/Curation">001A26</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001A26</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000C03</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000C03</idno>
<idno type="wicri:Area/Ncbi/Merge">005783</idno>
<idno type="wicri:Area/Ncbi/Curation">005783</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Oral squamous cell carcinoma in a patient treated with long-term pegylated liposomal doxorubicin for recurrent ovarian cancer</title>
<author><name sortKey="Pezzoli, Matteo" sort="Pezzoli, Matteo" uniqKey="Pezzoli M" first="Matteo" last="Pezzoli">Matteo Pezzoli</name>
</author>
<author><name sortKey="Bona Galvagno, Maurizio" sort="Bona Galvagno, Maurizio" uniqKey="Bona Galvagno M" first="Maurizio" last="Bona Galvagno">Maurizio Bona Galvagno</name>
</author>
<author><name sortKey="Bongioannini, Guido" sort="Bongioannini, Guido" uniqKey="Bongioannini G" first="Guido" last="Bongioannini">Guido Bongioannini</name>
</author>
</analytic>
<series><title level="j">BMJ Case Reports</title>
<idno type="eISSN">1757-790X</idno>
<imprint><date when="2015">2015</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>We present a case of a woman who developed an oral squamous cell carcinoma (SCC) after being treated for a recurrent ovarian carcinoma with subtotal gastric resection and adjuvant pegylated liposomal doxorubicin (PLD). She received six cycles of PLD induction and maintenance therapy, which was continued for 5 years. She was free from disease at the following visits but 3 years later she developed SCC of her left inferior edentulous gums. The patient was negative for human papillomavirus and had never smoked in her life or had a history of alcohol use or any other environmental risk factors. PLD is known to accumulate in eccrine glands of the hands and the feet and in the oral mucosa, therefore causing skin toxicity and mucositis. It is conceivable that this specific biodistribution to the oral mucosa may be responsible for the onset of SCC.</p>
</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 005783 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 005783 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= EdenteV2 |flux= Ncbi |étape= Curation |type= RBID |clé= PMC:4307081 |texte= Oral squamous cell carcinoma in a patient treated with long-term pegylated liposomal doxorubicin for recurrent ovarian cancer }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:25589526" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \ | NlmPubMed2Wicri -a EdenteV2
This area was generated with Dilib version V0.6.32. |