Clear Cell Myoepithelioma of Palate with Emphasis on Clinical and Histological Differential Diagnosis
Identifieur interne : 005097 ( Ncbi/Curation ); précédent : 005096; suivant : 005098Clear Cell Myoepithelioma of Palate with Emphasis on Clinical and Histological Differential Diagnosis
Auteurs : Bindu J. Nair [Inde] ; Velayudhannair Vivek [Inde] ; Trivandrum T. Sivakumar [Inde] ; Anna P. Joseph [Inde] ; Babyamma Raghavanpillai Varun [Inde] ; Vinod Mony [Inde]Source :
- Clinics and Practice [ 2039-7275 ] ; 2014.
Abstract
Myoepitheliomas account for less than 1% of all salivary gland tumors and mostly occur in the parotid gland and palate. A 58-year old male patient reported to the Outpatient Department of PMS College of Dental Science and Research (Kerala, India) with a slow growing painless swelling on the palate for 4 years. Pleomorphic adenoma, basal cell adenoma, myoepithelioma, cyst adenoma, lipoma, neurofibroma, neurilemmoma and leiomyoma were considered. Histopathology revealed a thinly encapsulated tumor composed mainly of sheets of clear cells mixed with cells having eosinophilic cytoplasm. Histopathological differential diagnosis included pleomorphic adenoma, oncocytoma, oncocytic hyperplasia, sebaceous adenoma, malignant salivary gland neoplasms and metastatic lesions from kidney and thyroid. Myoepitheliomas mostly occur in the parotid gland and palatal region and various histological types of myoepithelioma are described. Myoepitheliomas of the palate are rare with clear cell variant even rarer.
Url:
DOI: 10.4081/cp.2014.628
PubMed: 24847433
PubMed Central: 4019922
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Nair</name><affiliation wicri:level="1"><nlm:aff id="aff001">Department of Oral Pathology and Microbiology,<institution>PMS College of Dental Science and Research</institution>,<addr-line>Kerala, India</addr-line></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Kerala</wicri:regionArea></affiliation></author><author><name sortKey="Vivek, Velayudhannair" sort="Vivek, Velayudhannair" uniqKey="Vivek V" first="Velayudhannair" last="Vivek">Velayudhannair Vivek</name><affiliation wicri:level="1"><nlm:aff id="aff002">Department of Oral Medicine and Radiology,<institution>PMS College of Dental Science and Research</institution>,<addr-line>Kerala, India</addr-line></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Kerala</wicri:regionArea></affiliation></author><author><name sortKey="Sivakumar, Trivandrum T" sort="Sivakumar, Trivandrum T" uniqKey="Sivakumar T" first="Trivandrum T." last="Sivakumar">Trivandrum T. Sivakumar</name><affiliation wicri:level="1"><nlm:aff id="aff001">Department of Oral Pathology and Microbiology,<institution>PMS College of Dental Science and Research</institution>,<addr-line>Kerala, India</addr-line></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Kerala</wicri:regionArea></affiliation></author><author><name sortKey="Joseph, Anna P" sort="Joseph, Anna P" uniqKey="Joseph A" first="Anna P." last="Joseph">Anna P. Joseph</name><affiliation wicri:level="1"><nlm:aff id="aff001">Department of Oral Pathology and Microbiology,<institution>PMS College of Dental Science and Research</institution>,<addr-line>Kerala, India</addr-line></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Kerala</wicri:regionArea></affiliation></author><author><name sortKey="Varun, Babyamma Raghavanpillai" sort="Varun, Babyamma Raghavanpillai" uniqKey="Varun B" first="Babyamma Raghavanpillai" last="Varun">Babyamma Raghavanpillai Varun</name><affiliation wicri:level="1"><nlm:aff id="aff001">Department of Oral Pathology and Microbiology,<institution>PMS College of Dental Science and Research</institution>,<addr-line>Kerala, India</addr-line></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Kerala</wicri:regionArea></affiliation></author><author><name sortKey="Mony, Vinod" sort="Mony, Vinod" uniqKey="Mony V" first="Vinod" last="Mony">Vinod Mony</name><affiliation wicri:level="1"><nlm:aff id="aff001">Department of Oral Pathology and Microbiology,<institution>PMS College of Dental Science and Research</institution>,<addr-line>Kerala, India</addr-line></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Kerala</wicri:regionArea></affiliation></author></analytic><series><title level="j">Clinics and Practice</title><idno type="ISSN">2039-7275</idno><idno type="eISSN">2039-7283</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Myoepitheliomas account for less than 1% of all salivary gland tumors and mostly occur in the parotid gland and palate. A 58-year old male patient reported to the Outpatient Department of PMS College of Dental Science and Research (Kerala, India) with a slow growing painless swelling on the palate for 4 years. Pleomorphic adenoma, basal cell adenoma, myoepithelioma, cyst adenoma, lipoma, neurofibroma, neurilemmoma and leiomyoma were considered. Histopathology revealed a thinly encapsulated tumor composed mainly of sheets of clear cells mixed with cells having eosinophilic cytoplasm. Histopathological differential diagnosis included pleomorphic adenoma, oncocytoma, oncocytic hyperplasia, sebaceous adenoma, malignant salivary gland neoplasms and metastatic lesions from kidney and thyroid. Myoepitheliomas mostly occur in the parotid gland and palatal region and various histological types of myoepithelioma are described. 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