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Comparison of Adjustable and Fixed Oral Appliances for the Treatment of Obstructive Sleep Apnea

Identifieur interne : 003937 ( Ncbi/Curation ); précédent : 003936; suivant : 003938

Comparison of Adjustable and Fixed Oral Appliances for the Treatment of Obstructive Sleep Apnea

Auteurs : Christopher J. Lettieri [États-Unis] ; Nathalie Paolino [États-Unis] ; Arn H. Eliasson [États-Unis] ; Anita A. Shah [États-Unis] ; Aaron B. Holley [États-Unis]

Source :

Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine [ 1550-9389 ] ; 2011.

RBID : PMC:3190841

Abstract

Study Objectives:

To compare the efficacy of adjustable and fixed oral appliances for the treatment of OSA.

Methods:

Retrospective review of consecutive patients with OSA treated with either adjustable or fixed oral appliances. Polysomnography was conducted before and during therapy. Effective treatment was defined as an apnea-hypopnea index (AHI) < 5 events/h or < 10 events/h with resolution of sleepiness (Epworth < 10). We compared efficacy rates between fixed and adjustable appliances and sought to identify factors associated with greater success.

Results:

We included 805 patients, 602 (74.8%) treated with an adjustable and 203 (25.2%) a fixed oral appliances. Among the cohort, 86.4% were men; mean age was 41.3 ± 9.2 years. Mean AHI was 30.7 ± 25.6, with 34.1% having mild (AHI 5-14.9), 29.2% moderate (AHI 15-29.9), and 36.8% severe (AHI ≥ 30) OSA. Successful therapy was significantly more common with adjustable appliances. Obstructive events were reduced to < 5/h in 56.8% with adjustable compared to 47.0% with fixed appliances (p = 0.02). Similarly, a reduction of events to < 10 with resolution of sleepiness occurred in 66.4% with adjustable appliances versus 44.9% with fixed appliances (p < 0.001). For both devices, success was more common in younger patients, with lower BMI and less severe disease.

Conclusions:

Adjustable devices produced greater reductions in obstructive events and were more likely to provide successful therapy, especially in moderate-severe OSA. Fixed appliances were effective in mild disease, but were less successful in those with higher AHIs. Given these findings, the baseline AHI should be considered when selecting the type of oral appliance.

Citation:

Lettieri CJ; Paolino N; Eliasson AH; Shah AA; Holley AB. Comparison of adjustable and fixed oral appliances for the treatment of obstructive sleep apnea. J Clin Sleep Med 2011;7(5):439-445.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190841

DOI: 10.5664/JCSM.1300
PubMed: 22003337
PubMed Central: 3190841

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PMC:3190841

Le document en format XML

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<front><div type="abstract" xml:lang="en"><sec><title>Study Objectives:</title>
<p>To compare the efficacy of adjustable and fixed oral appliances for the treatment of OSA.</p>
</sec>
<sec><title>Methods:</title>
<p> Retrospective review of consecutive patients with OSA treated with either adjustable or fixed oral appliances. Polysomnography was conducted before and during therapy. Effective treatment was defined as an apnea-hypopnea index (AHI) < 5 events/h or < 10 events/h with resolution of sleepiness (Epworth < 10). We compared efficacy rates between fixed and adjustable appliances and sought to identify factors associated with greater success.</p>
</sec>
<sec><title>Results:</title>
<p> We included 805 patients, 602 (74.8%) treated with an adjustable and 203 (25.2%) a fixed oral appliances. Among the cohort, 86.4% were men; mean age was 41.3 ± 9.2 years. Mean AHI was 30.7 ± 25.6, with 34.1% having mild (AHI 5-14.9), 29.2% moderate (AHI 15-29.9), and 36.8% severe (AHI ≥ 30) OSA. Successful therapy was significantly more common with adjustable appliances. Obstructive events were reduced to < 5/h in 56.8% with adjustable compared to 47.0% with fixed appliances (p = 0.02). Similarly, a reduction of events to < 10 with resolution of sleepiness occurred in 66.4% with adjustable appliances versus 44.9% with fixed appliances (p < 0.001). For both devices, success was more common in younger patients, with lower BMI and less severe disease.</p>
</sec>
<sec><title>Conclusions:</title>
<p> Adjustable devices produced greater reductions in obstructive events and were more likely to provide successful therapy, especially in moderate-severe OSA. Fixed appliances were effective in mild disease, but were less successful in those with higher AHIs. Given these findings, the baseline AHI should be considered when selecting the type of oral appliance.</p>
</sec>
<sec><title>Citation:</title>
<p> Lettieri CJ; Paolino N; Eliasson AH; Shah AA; Holley AB. Comparison of adjustable and fixed oral appliances for the treatment of obstructive sleep apnea. <italic>J Clin Sleep Med</italic>
 2011;7(5):439-445.</p>
</sec>
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</front>
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Comparison of Adjustable and Fixed Oral Appliances for the Treatment of Obstructive Sleep Apnea

Comparison of Adjustable and Fixed Oral Appliances for the Treatment of Obstructive Sleep Apnea

Source :

Abstract

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