Periodontitis Predicts Elevated C-reactive Protein Levels in Chronic Kidney Disease
Identifieur interne : 003889 ( Ncbi/Checkpoint ); précédent : 003888; suivant : 003890Periodontitis Predicts Elevated C-reactive Protein Levels in Chronic Kidney Disease
Auteurs : E. Ioannidou ; H. Swede [États-Unis] ; A. Dongari-BagtzoglouSource :
- Journal of Dental Research [ 0022-0345 ] ; 2011.
Abstract
Based on the existing evidence supporting a state of chronic inflammation in chronic kidney disease (CKD), we hypothesized that periodontal infection may affect the systemic inflammatory status of a nationally representative CKD population as measured by serum C-reactive protein (CRP). We examined this hypothesis using the National Health and Nutrition Examination Survey 1988-1994 (NHANES III) dataset including 2303 individuals. We followed the American Academy of Periodontology (AAP)/Centers for Disease Control and Prevention (CDC) case definition for periodontitis. We used a cutoff point of 30% sites with (PD) ≥ 5 mm and (CAL) ≥ 4 mm to define generalized periodontitis cases. We estimated glomerular filtration rate based on cystatin C levels using the relevant equation. Urinary albumin-to-creatinine ratio was calculated in milligrams
Url:
DOI: 10.1177/0022034511423394
PubMed: 21940520
PubMed Central: 3215758
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 002419
- to stream Pmc, to step Curation: 002419
- to stream Pmc, to step Checkpoint: 002105
- to stream Ncbi, to step Merge: 003889
- to stream Ncbi, to step Curation: 003889
Links to Exploration step
PMC:3215758Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Periodontitis Predicts Elevated C-reactive Protein Levels in Chronic Kidney Disease</title>
<author><name sortKey="Ioannidou, E" sort="Ioannidou, E" uniqKey="Ioannidou E" first="E." last="Ioannidou">E. Ioannidou</name>
<affiliation><nlm:aff id="aff1-0022034511423394">Division of Periodontology, Department of Oral Health and Diagnostic Sciences</nlm:aff>
<wicri:noCountry code="subfield">Department of Oral Health and Diagnostic Sciences</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Swede, H" sort="Swede, H" uniqKey="Swede H" first="H." last="Swede">H. Swede</name>
<affiliation wicri:level="2"><nlm:aff id="aff2-0022034511423394">Division of Epidemiology and Biostatistics, Department of Community Medicine and Health Care, University of Connecticut Health Center, 263 Farmington Ave., Farmington, CT 06030, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Epidemiology and Biostatistics, Department of Community Medicine and Health Care, University of Connecticut Health Center, 263 Farmington Ave., Farmington, CT 06030</wicri:regionArea>
<placeName><region type="state">Connecticut</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Dongari Bagtzoglou, A" sort="Dongari Bagtzoglou, A" uniqKey="Dongari Bagtzoglou A" first="A." last="Dongari-Bagtzoglou">A. Dongari-Bagtzoglou</name>
<affiliation><nlm:aff id="aff1-0022034511423394">Division of Periodontology, Department of Oral Health and Diagnostic Sciences</nlm:aff>
<wicri:noCountry code="subfield">Department of Oral Health and Diagnostic Sciences</wicri:noCountry>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">21940520</idno>
<idno type="pmc">3215758</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215758</idno>
<idno type="RBID">PMC:3215758</idno>
<idno type="doi">10.1177/0022034511423394</idno>
<date when="2011">2011</date>
<idno type="wicri:Area/Pmc/Corpus">002419</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002419</idno>
<idno type="wicri:Area/Pmc/Curation">002419</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002419</idno>
<idno type="wicri:Area/Pmc/Checkpoint">002105</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002105</idno>
<idno type="wicri:Area/Ncbi/Merge">003889</idno>
<idno type="wicri:Area/Ncbi/Curation">003889</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">003889</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Periodontitis Predicts Elevated C-reactive Protein Levels in Chronic Kidney Disease</title>
<author><name sortKey="Ioannidou, E" sort="Ioannidou, E" uniqKey="Ioannidou E" first="E." last="Ioannidou">E. Ioannidou</name>
<affiliation><nlm:aff id="aff1-0022034511423394">Division of Periodontology, Department of Oral Health and Diagnostic Sciences</nlm:aff>
<wicri:noCountry code="subfield">Department of Oral Health and Diagnostic Sciences</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Swede, H" sort="Swede, H" uniqKey="Swede H" first="H." last="Swede">H. Swede</name>
<affiliation wicri:level="2"><nlm:aff id="aff2-0022034511423394">Division of Epidemiology and Biostatistics, Department of Community Medicine and Health Care, University of Connecticut Health Center, 263 Farmington Ave., Farmington, CT 06030, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Epidemiology and Biostatistics, Department of Community Medicine and Health Care, University of Connecticut Health Center, 263 Farmington Ave., Farmington, CT 06030</wicri:regionArea>
<placeName><region type="state">Connecticut</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Dongari Bagtzoglou, A" sort="Dongari Bagtzoglou, A" uniqKey="Dongari Bagtzoglou A" first="A." last="Dongari-Bagtzoglou">A. Dongari-Bagtzoglou</name>
<affiliation><nlm:aff id="aff1-0022034511423394">Division of Periodontology, Department of Oral Health and Diagnostic Sciences</nlm:aff>
<wicri:noCountry code="subfield">Department of Oral Health and Diagnostic Sciences</wicri:noCountry>
</affiliation>
</author>
</analytic>
<series><title level="j">Journal of Dental Research</title>
<idno type="ISSN">0022-0345</idno>
<idno type="eISSN">1544-0591</idno>
<imprint><date when="2011">2011</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>Based on the existing evidence supporting a state of chronic inflammation in chronic kidney disease (CKD), we hypothesized that periodontal infection may affect the systemic inflammatory status of a nationally representative CKD population as measured by serum C-reactive protein (CRP). We examined this hypothesis using the National Health and Nutrition Examination Survey 1988-1994 (NHANES III) dataset including 2303 individuals. We followed the American Academy of Periodontology (AAP)/Centers for Disease Control and Prevention (CDC) case definition for periodontitis. We used a cutoff point of 30% sites with (PD) ≥ 5 mm and (CAL) ≥ 4 mm to define generalized periodontitis cases. We estimated glomerular filtration rate based on cystatin C levels using the relevant equation. Urinary albumin-to-creatinine ratio was calculated in milligrams <italic>per</italic>
gram with a cutoff point of 30 mg/g. CKD was defined based on eGFR < 60 mL/min/1.73m<sup>2</sup>
and albuminuria ≥ 30 mg/g. Periodontitis was found in 427 (12.3%) individuals. Of individuals with periodontitis, 41.8% had serum CRP higher than 0.3 mg/dL compared with 27.1% of non-periodontitis and 53.1% of edentulous individuals (p = 0.001 for all comparisons). When the extent of periodontitis was used as one of the independent variables, the parsimonious model showed a strong independent association between extent of periodontitis and serum CRP levels (OR = 2.0, CI95% = 1.2-3.6).</p>
</div>
</front>
</TEI>
<affiliations><list><country><li>États-Unis</li>
</country>
<region><li>Connecticut</li>
</region>
</list>
<tree><noCountry><name sortKey="Dongari Bagtzoglou, A" sort="Dongari Bagtzoglou, A" uniqKey="Dongari Bagtzoglou A" first="A." last="Dongari-Bagtzoglou">A. Dongari-Bagtzoglou</name>
<name sortKey="Ioannidou, E" sort="Ioannidou, E" uniqKey="Ioannidou E" first="E." last="Ioannidou">E. Ioannidou</name>
</noCountry>
<country name="États-Unis"><region name="Connecticut"><name sortKey="Swede, H" sort="Swede, H" uniqKey="Swede H" first="H." last="Swede">H. Swede</name>
</region>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Ncbi/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003889 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd -nk 003889 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= EdenteV2 |flux= Ncbi |étape= Checkpoint |type= RBID |clé= PMC:3215758 |texte= Periodontitis Predicts Elevated C-reactive Protein Levels in Chronic Kidney Disease }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/RBID.i -Sk "pubmed:21940520" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd \ | NlmPubMed2Wicri -a EdenteV2
![]() | This area was generated with Dilib version V0.6.32. | ![]() |