Response shift masks the treatment impact on patient reported outcomes (PROs): the example of individual quality of life in edentulous patients
Identifieur interne : 001779 ( Ncbi/Checkpoint ); précédent : 001778; suivant : 001780Response shift masks the treatment impact on patient reported outcomes (PROs): the example of individual quality of life in edentulous patients
Auteurs : Lena Ring [Irlande (pays), Suède] ; Stefan Höfer [Irlande (pays), Autriche] ; Frank Heuston [Irlande (pays)] ; David Harris [Irlande (pays)] ; Ciaran A. O'Boyle [Irlande (pays)]Source :
- Health and Quality of Life Outcomes [ 1477-7525 ] ; 2005.
Descripteurs français
- KwdFr :
- Adaptation psychologique, Adulte d'âge moyen, Bouche édentée (), Bouche édentée (psychologie), Concept du soi, Enquêtes et questionnaires, Facteurs temps, Femelle, Humains, Hôpitaux d'enseignement, Irlande, Mâle, Pose d'implant dentaire endo-osseux (psychologie), Prothèse dentaire complète (psychologie), Psychométrie, Qualité de vie (psychologie), Résultat thérapeutique, Satisfaction du patient, Service hospitalier d'odontologie, Sujet âgé.
- MESH :
- psychologie : Bouche édentée, Pose d'implant dentaire endo-osseux, Prothèse dentaire complète, Qualité de vie.
- Adaptation psychologique, Adulte d'âge moyen, Bouche édentée, Concept du soi, Enquêtes et questionnaires, Facteurs temps, Femelle, Humains, Hôpitaux d'enseignement, Irlande, Mâle, Psychométrie, Résultat thérapeutique, Satisfaction du patient, Service hospitalier d'odontologie, Sujet âgé.
English descriptors
- KwdEn :
- Adaptation, Psychological, Aged, Dental Implantation, Endosseous (psychology), Dental Service, Hospital, Denture, Complete (psychology), Female, Hospitals, Teaching, Humans, Ireland, Male, Middle Aged, Mouth, Edentulous (psychology), Mouth, Edentulous (surgery), Mouth, Edentulous (therapy), Patient Satisfaction, Psychometrics, Quality of Life (psychology), Self Concept, Surveys and Questionnaires, Time Factors, Treatment Outcome.
- MESH :
- geographic : Ireland.
- psychology : Dental Implantation, Endosseous, Denture, Complete, Mouth, Edentulous, Quality of Life.
- surgery : Mouth, Edentulous.
- therapy : Mouth, Edentulous.
- Adaptation, Psychological, Aged, Dental Service, Hospital, Female, Hospitals, Teaching, Humans, Male, Middle Aged, Patient Satisfaction, Psychometrics, Self Concept, Surveys and Questionnaires, Time Factors, Treatment Outcome.
Abstract
Quality of life (QoL) is now established as an important outcome for evaluating the impact of disease, and for assessing the efficacy of treatments. However, individuals change with time and the basis on which they make a QoL judgement may also change, a phenomenon increasingly referred to as response shift. Here, the individual may change his or her internal standards, values, and/or conceptualization on the target construct as a result of external factors such as a treatment or a change in health status. This has important implications for assessing the effects of treatments as a change in QoL may reflect a response shift, a treatment effect, or a complex combination of both. In this study, we used an individualised quality of life (IQoL) measure, the SEIQoL, together with a then-test to determine whether response shift would influence the measurement of treatment efficacy in edentulous patients.
Data are reported here for the first phase of a randomised controlled clinical trial designed to assess the impact, on IQoL, of implant supported dentures compared with high quality conventional dentures. IQoL was measured using the SEIQoL-DW in 117 patients (mean age 64.8; 32% male) at baseline (T1) and 3 months (T2) after receiving high quality conventional dentures. The work was carried out in dental teaching hospitals in Dublin and Belfast.
Unadjusted SEIQoL index scores revealed no significant impact of treatment at three months (baseline: 75.0; 3 months: 73.2, p = .33, n.s.). However, the then-test at 3 months revealed that patients retrospectively rated their baseline IQoL as significantly lower (P < .001) than they had rated it at the time (then-test baseline: 69.2). Comparison of the 3 month scores with this readjusted baseline indicated a significant treatment effect (then-test baseline: 69.2; 3 months: 73.2, p = 0.016). 81% of patients nominated at least one different IQoL domain at 3 months.
The positive impact of denture treatment for edentulous patients on IQoL was seen only when response shifts were taken into consideration. The nature of the response shifts was highly complex but the data indicated a degree of re-conceptualisation and reprioritisation. Assessment of the impact of treatments using patient-generated reports must take account of the adaptive nature of patients.
Url:
DOI: 10.1186/1477-7525-3-55
PubMed: 16146573
PubMed Central: 1236951
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 001876
- to stream Pmc, to step Curation: 001876
- to stream Pmc, to step Checkpoint: 002758
- to stream PubMed, to step Corpus: 002917
- to stream PubMed, to step Curation: 002917
- to stream PubMed, to step Checkpoint: 002917
- to stream Ncbi, to step Merge: 001779
- to stream Ncbi, to step Curation: 001779
Links to Exploration step
PMC:1236951Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Response shift masks the treatment impact on patient reported outcomes (PROs): the example of individual quality of life in edentulous patients</title>
<author><name sortKey="Ring, Lena" sort="Ring, Lena" uniqKey="Ring L" first="Lena" last="Ring">Lena Ring</name>
<affiliation wicri:level="1"><nlm:aff id="I1">Department of Psychology, Royal College of Surgeons in Ireland, Mercer Street Lower, Dublin 2, Ireland</nlm:aff>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>Department of Psychology, Royal College of Surgeons in Ireland, Mercer Street Lower, Dublin 2</wicri:regionArea>
<wicri:noRegion>Dublin 2</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="I2">Dept of Pharmacy, BMC, Box 580, 751 23 Uppsala, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Dept of Pharmacy, BMC, Box 580, 751 23 Uppsala</wicri:regionArea>
<wicri:noRegion>751 23 Uppsala</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hofer, Stefan" sort="Hofer, Stefan" uniqKey="Hofer S" first="Stefan" last="Höfer">Stefan Höfer</name>
<affiliation wicri:level="1"><nlm:aff id="I1">Department of Psychology, Royal College of Surgeons in Ireland, Mercer Street Lower, Dublin 2, Ireland</nlm:aff>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>Department of Psychology, Royal College of Surgeons in Ireland, Mercer Street Lower, Dublin 2</wicri:regionArea>
<wicri:noRegion>Dublin 2</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="I3">Department of Medical Psychology and Psychotherapy, Medical University Innsbruck, Innsbruck, Austria</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Department of Medical Psychology and Psychotherapy, Medical University Innsbruck, Innsbruck</wicri:regionArea>
<wicri:noRegion>Innsbruck</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Heuston, Frank" sort="Heuston, Frank" uniqKey="Heuston F" first="Frank" last="Heuston">Frank Heuston</name>
<affiliation wicri:level="1"><nlm:aff id="I4">Department of Restorative Dentistry & Periodontology, Dublin Dental Hospital, Dublin 2, Ireland</nlm:aff>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>Department of Restorative Dentistry & Periodontology, Dublin Dental Hospital, Dublin 2</wicri:regionArea>
<wicri:noRegion>Dublin 2</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Harris, David" sort="Harris, David" uniqKey="Harris D" first="David" last="Harris">David Harris</name>
<affiliation wicri:level="1"><nlm:aff id="I5">The School of Dental Sciences, Trinity College, Dublin 2, Ireland</nlm:aff>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>The School of Dental Sciences, Trinity College, Dublin 2</wicri:regionArea>
<wicri:noRegion>Dublin 2</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="O Boyle, Ciaran A" sort="O Boyle, Ciaran A" uniqKey="O Boyle C" first="Ciaran A" last="O'Boyle">Ciaran A. O'Boyle</name>
<affiliation wicri:level="1"><nlm:aff id="I1">Department of Psychology, Royal College of Surgeons in Ireland, Mercer Street Lower, Dublin 2, Ireland</nlm:aff>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>Department of Psychology, Royal College of Surgeons in Ireland, Mercer Street Lower, Dublin 2</wicri:regionArea>
<wicri:noRegion>Dublin 2</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">16146573</idno>
<idno type="pmc">1236951</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1236951</idno>
<idno type="RBID">PMC:1236951</idno>
<idno type="doi">10.1186/1477-7525-3-55</idno>
<date when="2005">2005</date>
<idno type="wicri:Area/Pmc/Corpus">001876</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001876</idno>
<idno type="wicri:Area/Pmc/Curation">001876</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001876</idno>
<idno type="wicri:Area/Pmc/Checkpoint">002758</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002758</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="wicri:Area/PubMed/Corpus">002917</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002917</idno>
<idno type="wicri:Area/PubMed/Curation">002917</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002917</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002917</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002917</idno>
<idno type="wicri:Area/Ncbi/Merge">001779</idno>
<idno type="wicri:Area/Ncbi/Curation">001779</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001779</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Response shift masks the treatment impact on patient reported outcomes (PROs): the example of individual quality of life in edentulous patients</title>
<author><name sortKey="Ring, Lena" sort="Ring, Lena" uniqKey="Ring L" first="Lena" last="Ring">Lena Ring</name>
<affiliation wicri:level="1"><nlm:aff id="I1">Department of Psychology, Royal College of Surgeons in Ireland, Mercer Street Lower, Dublin 2, Ireland</nlm:aff>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>Department of Psychology, Royal College of Surgeons in Ireland, Mercer Street Lower, Dublin 2</wicri:regionArea>
<wicri:noRegion>Dublin 2</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="I2">Dept of Pharmacy, BMC, Box 580, 751 23 Uppsala, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Dept of Pharmacy, BMC, Box 580, 751 23 Uppsala</wicri:regionArea>
<wicri:noRegion>751 23 Uppsala</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hofer, Stefan" sort="Hofer, Stefan" uniqKey="Hofer S" first="Stefan" last="Höfer">Stefan Höfer</name>
<affiliation wicri:level="1"><nlm:aff id="I1">Department of Psychology, Royal College of Surgeons in Ireland, Mercer Street Lower, Dublin 2, Ireland</nlm:aff>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>Department of Psychology, Royal College of Surgeons in Ireland, Mercer Street Lower, Dublin 2</wicri:regionArea>
<wicri:noRegion>Dublin 2</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="I3">Department of Medical Psychology and Psychotherapy, Medical University Innsbruck, Innsbruck, Austria</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Department of Medical Psychology and Psychotherapy, Medical University Innsbruck, Innsbruck</wicri:regionArea>
<wicri:noRegion>Innsbruck</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Heuston, Frank" sort="Heuston, Frank" uniqKey="Heuston F" first="Frank" last="Heuston">Frank Heuston</name>
<affiliation wicri:level="1"><nlm:aff id="I4">Department of Restorative Dentistry & Periodontology, Dublin Dental Hospital, Dublin 2, Ireland</nlm:aff>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>Department of Restorative Dentistry & Periodontology, Dublin Dental Hospital, Dublin 2</wicri:regionArea>
<wicri:noRegion>Dublin 2</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Harris, David" sort="Harris, David" uniqKey="Harris D" first="David" last="Harris">David Harris</name>
<affiliation wicri:level="1"><nlm:aff id="I5">The School of Dental Sciences, Trinity College, Dublin 2, Ireland</nlm:aff>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>The School of Dental Sciences, Trinity College, Dublin 2</wicri:regionArea>
<wicri:noRegion>Dublin 2</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="O Boyle, Ciaran A" sort="O Boyle, Ciaran A" uniqKey="O Boyle C" first="Ciaran A" last="O'Boyle">Ciaran A. O'Boyle</name>
<affiliation wicri:level="1"><nlm:aff id="I1">Department of Psychology, Royal College of Surgeons in Ireland, Mercer Street Lower, Dublin 2, Ireland</nlm:aff>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>Department of Psychology, Royal College of Surgeons in Ireland, Mercer Street Lower, Dublin 2</wicri:regionArea>
<wicri:noRegion>Dublin 2</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Health and Quality of Life Outcomes</title>
<idno type="eISSN">1477-7525</idno>
<imprint><date when="2005">2005</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adaptation, Psychological</term>
<term>Aged</term>
<term>Dental Implantation, Endosseous (psychology)</term>
<term>Dental Service, Hospital</term>
<term>Denture, Complete (psychology)</term>
<term>Female</term>
<term>Hospitals, Teaching</term>
<term>Humans</term>
<term>Ireland</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Mouth, Edentulous (psychology)</term>
<term>Mouth, Edentulous (surgery)</term>
<term>Mouth, Edentulous (therapy)</term>
<term>Patient Satisfaction</term>
<term>Psychometrics</term>
<term>Quality of Life (psychology)</term>
<term>Self Concept</term>
<term>Surveys and Questionnaires</term>
<term>Time Factors</term>
<term>Treatment Outcome</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adaptation psychologique</term>
<term>Adulte d'âge moyen</term>
<term>Bouche édentée ()</term>
<term>Bouche édentée (psychologie)</term>
<term>Concept du soi</term>
<term>Enquêtes et questionnaires</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Humains</term>
<term>Hôpitaux d'enseignement</term>
<term>Irlande</term>
<term>Mâle</term>
<term>Pose d'implant dentaire endo-osseux (psychologie)</term>
<term>Prothèse dentaire complète (psychologie)</term>
<term>Psychométrie</term>
<term>Qualité de vie (psychologie)</term>
<term>Résultat thérapeutique</term>
<term>Satisfaction du patient</term>
<term>Service hospitalier d'odontologie</term>
<term>Sujet âgé</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>Ireland</term>
</keywords>
<keywords scheme="MESH" qualifier="psychologie" xml:lang="fr"><term>Bouche édentée</term>
<term>Pose d'implant dentaire endo-osseux</term>
<term>Prothèse dentaire complète</term>
<term>Qualité de vie</term>
</keywords>
<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Dental Implantation, Endosseous</term>
<term>Denture, Complete</term>
<term>Mouth, Edentulous</term>
<term>Quality of Life</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Mouth, Edentulous</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Mouth, Edentulous</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adaptation, Psychological</term>
<term>Aged</term>
<term>Dental Service, Hospital</term>
<term>Female</term>
<term>Hospitals, Teaching</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Patient Satisfaction</term>
<term>Psychometrics</term>
<term>Self Concept</term>
<term>Surveys and Questionnaires</term>
<term>Time Factors</term>
<term>Treatment Outcome</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adaptation psychologique</term>
<term>Adulte d'âge moyen</term>
<term>Bouche édentée</term>
<term>Concept du soi</term>
<term>Enquêtes et questionnaires</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Humains</term>
<term>Hôpitaux d'enseignement</term>
<term>Irlande</term>
<term>Mâle</term>
<term>Psychométrie</term>
<term>Résultat thérapeutique</term>
<term>Satisfaction du patient</term>
<term>Service hospitalier d'odontologie</term>
<term>Sujet âgé</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec><title>Background</title>
<p>Quality of life (QoL) is now established as an important outcome for evaluating the impact of disease, and for assessing the efficacy of treatments. However, individuals change with time and the basis on which they make a QoL judgement may also change, a phenomenon increasingly referred to as response shift. Here, the individual may change his or her internal standards, values, and/or conceptualization on the target construct as a result of external factors such as a treatment or a change in health status. This has important implications for assessing the effects of treatments as a change in QoL may reflect a response shift, a treatment effect, or a complex combination of both. In this study, we used an individualised quality of life (IQoL) measure, the SEIQoL, together with a then-test to determine whether response shift would influence the measurement of treatment efficacy in edentulous patients.</p>
</sec>
<sec sec-type="methods"><title>Methods</title>
<p>Data are reported here for the first phase of a randomised controlled clinical trial designed to assess the impact, on IQoL, of implant supported dentures compared with high quality conventional dentures. IQoL was measured using the SEIQoL-DW in 117 patients (mean age 64.8; 32% male) at baseline (T<sub>1</sub>
) and 3 months (T<sub>2</sub>
) after receiving high quality conventional dentures. The work was carried out in dental teaching hospitals in Dublin and Belfast.</p>
</sec>
<sec><title>Results</title>
<p>Unadjusted SEIQoL index scores revealed no significant impact of treatment at three months (baseline: 75.0; 3 months: 73.2, p = .33, n.s.). However, the then-test at 3 months revealed that patients retrospectively rated their baseline IQoL as significantly lower (P < .001) than they had rated it at the time (then-test baseline: 69.2). Comparison of the 3 month scores with this readjusted baseline indicated a significant treatment effect (then-test baseline: 69.2; 3 months: 73.2, p = 0.016). 81% of patients nominated at least one different IQoL domain at 3 months.</p>
</sec>
<sec><title>Conclusion</title>
<p>The positive impact of denture treatment for edentulous patients on IQoL was seen only when response shifts were taken into consideration. The nature of the response shifts was highly complex but the data indicated a degree of re-conceptualisation and reprioritisation. Assessment of the impact of treatments using patient-generated reports must take account of the adaptive nature of patients.</p>
</sec>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<affiliations><list><country><li>Autriche</li>
<li>Irlande (pays)</li>
<li>Suède</li>
</country>
</list>
<tree><country name="Irlande (pays)"><noRegion><name sortKey="Ring, Lena" sort="Ring, Lena" uniqKey="Ring L" first="Lena" last="Ring">Lena Ring</name>
</noRegion>
<name sortKey="Harris, David" sort="Harris, David" uniqKey="Harris D" first="David" last="Harris">David Harris</name>
<name sortKey="Heuston, Frank" sort="Heuston, Frank" uniqKey="Heuston F" first="Frank" last="Heuston">Frank Heuston</name>
<name sortKey="Hofer, Stefan" sort="Hofer, Stefan" uniqKey="Hofer S" first="Stefan" last="Höfer">Stefan Höfer</name>
<name sortKey="O Boyle, Ciaran A" sort="O Boyle, Ciaran A" uniqKey="O Boyle C" first="Ciaran A" last="O'Boyle">Ciaran A. O'Boyle</name>
</country>
<country name="Suède"><noRegion><name sortKey="Ring, Lena" sort="Ring, Lena" uniqKey="Ring L" first="Lena" last="Ring">Lena Ring</name>
</noRegion>
</country>
<country name="Autriche"><noRegion><name sortKey="Hofer, Stefan" sort="Hofer, Stefan" uniqKey="Hofer S" first="Stefan" last="Höfer">Stefan Höfer</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Ncbi/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001779 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd -nk 001779 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= EdenteV2 |flux= Ncbi |étape= Checkpoint |type= RBID |clé= PMC:1236951 |texte= Response shift masks the treatment impact on patient reported outcomes (PROs): the example of individual quality of life in edentulous patients }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/RBID.i -Sk "pubmed:16146573" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd \ | NlmPubMed2Wicri -a EdenteV2
This area was generated with Dilib version V0.6.32. |