Histopathologic study of squamous cell carcinoma of the gingiva in edentulous and dentulous jaws of hamsters treated with N-methylnitrosourea.
Identifieur interne : 00BF42 ( Main/Merge ); précédent : 00BF41; suivant : 00BF43Histopathologic study of squamous cell carcinoma of the gingiva in edentulous and dentulous jaws of hamsters treated with N-methylnitrosourea.
Auteurs : T. Kohgo [Japon] ; H G Uy ; T. Iizuka ; M. Shindoh ; A. AmemiyaSource :
- Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology [ 0904-2512 ] ; 1990.
Descripteurs français
- KwdFr :
- 1-Méthyl-1-nitroso-urée (effets indésirables), Animaux, Carcinome épidermoïde (), Carcinome épidermoïde (anatomopathologie), Cricetinae, Denture, Desmodonte (anatomopathologie), Incidence, Invasion tumorale, Mesocricetus, Mâchoire édentée, Mâle, Occlusion dentaire, Processus alvéolaire (anatomopathologie), Tissu conjonctif (anatomopathologie), Tumeur de la gencive (), Tumeur de la gencive (anatomopathologie), Épithélium (anatomopathologie).
- MESH :
- anatomopathologie : Carcinome épidermoïde, Desmodonte, Processus alvéolaire, Tissu conjonctif, Tumeur de la gencive, Épithélium.
- effets indésirables : 1-Méthyl-1-nitroso-urée.
- Animaux, Carcinome épidermoïde, Cricetinae, Denture, Incidence, Invasion tumorale, Mesocricetus, Mâchoire édentée, Mâle, Occlusion dentaire, Tumeur de la gencive.
English descriptors
- KwdEn :
- Alveolar Process (pathology), Animals, Carcinoma, Squamous Cell (chemically induced), Carcinoma, Squamous Cell (pathology), Connective Tissue (pathology), Cricetinae, Dental Occlusion, Dentition, Epithelium (pathology), Gingival Neoplasms (chemically induced), Gingival Neoplasms (pathology), Incidence, Jaw, Edentulous, Male, Mesocricetus, Methylnitrosourea (adverse effects), Neoplasm Invasiveness, Periodontal Ligament (pathology).
- MESH :
- chemical , adverse effects : Methylnitrosourea.
- chemically induced : Carcinoma, Squamous Cell, Gingival Neoplasms.
- pathology : Alveolar Process, Carcinoma, Squamous Cell, Connective Tissue, Epithelium, Gingival Neoplasms, Periodontal Ligament.
- Animals, Cricetinae, Dental Occlusion, Dentition, Incidence, Jaw, Edentulous, Male, Mesocricetus, Neoplasm Invasiveness.
Abstract
Unilateral maxillary or mandibular molars were extracted from twenty-four, 25-day-old male syrian golden hamsters; 25 days after extraction, 20 received MNU intragastrically twice a week for 3 months. All animals were killed 1 month later. High degrees and incidence of invasion of gingival SCC were observed in dentulous jaws without functional occlusion, followed by dentulous jaws with functional occlusion and edentulous jaws. Invasion of carcinomas with extensive bone destruction was observed commonly in the gingiva of dentulous maxillary jaws without functional occlusion, but was scarcely observed in the gingiva of edentulous jaws. By analogy, disuse atrophy of the periodontium due to loss of functional occlusion may result in early deeper invasion, while loss of periodontal ligament due to tooth extraction and disappearance of so-called inner gingival epithelium may result in less invasive carcinomas.
PubMed: 2359038
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pubmed:2359038Le document en format XML
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<term>Animals</term>
<term>Carcinoma, Squamous Cell (chemically induced)</term>
<term>Carcinoma, Squamous Cell (pathology)</term>
<term>Connective Tissue (pathology)</term>
<term>Cricetinae</term>
<term>Dental Occlusion</term>
<term>Dentition</term>
<term>Epithelium (pathology)</term>
<term>Gingival Neoplasms (chemically induced)</term>
<term>Gingival Neoplasms (pathology)</term>
<term>Incidence</term>
<term>Jaw, Edentulous</term>
<term>Male</term>
<term>Mesocricetus</term>
<term>Methylnitrosourea (adverse effects)</term>
<term>Neoplasm Invasiveness</term>
<term>Periodontal Ligament (pathology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>1-Méthyl-1-nitroso-urée (effets indésirables)</term>
<term>Animaux</term>
<term>Carcinome épidermoïde ()</term>
<term>Carcinome épidermoïde (anatomopathologie)</term>
<term>Cricetinae</term>
<term>Denture</term>
<term>Desmodonte (anatomopathologie)</term>
<term>Incidence</term>
<term>Invasion tumorale</term>
<term>Mesocricetus</term>
<term>Mâchoire édentée</term>
<term>Mâle</term>
<term>Occlusion dentaire</term>
<term>Processus alvéolaire (anatomopathologie)</term>
<term>Tissu conjonctif (anatomopathologie)</term>
<term>Tumeur de la gencive ()</term>
<term>Tumeur de la gencive (anatomopathologie)</term>
<term>Épithélium (anatomopathologie)</term>
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<term>Desmodonte</term>
<term>Processus alvéolaire</term>
<term>Tissu conjonctif</term>
<term>Tumeur de la gencive</term>
<term>Épithélium</term>
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<term>Gingival Neoplasms</term>
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<term>Carcinoma, Squamous Cell</term>
<term>Connective Tissue</term>
<term>Epithelium</term>
<term>Gingival Neoplasms</term>
<term>Periodontal Ligament</term>
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<term>Cricetinae</term>
<term>Dental Occlusion</term>
<term>Dentition</term>
<term>Incidence</term>
<term>Jaw, Edentulous</term>
<term>Male</term>
<term>Mesocricetus</term>
<term>Neoplasm Invasiveness</term>
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<term>Carcinome épidermoïde</term>
<term>Cricetinae</term>
<term>Denture</term>
<term>Incidence</term>
<term>Invasion tumorale</term>
<term>Mesocricetus</term>
<term>Mâchoire édentée</term>
<term>Mâle</term>
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<front><div type="abstract" xml:lang="en">Unilateral maxillary or mandibular molars were extracted from twenty-four, 25-day-old male syrian golden hamsters; 25 days after extraction, 20 received MNU intragastrically twice a week for 3 months. All animals were killed 1 month later. High degrees and incidence of invasion of gingival SCC were observed in dentulous jaws without functional occlusion, followed by dentulous jaws with functional occlusion and edentulous jaws. Invasion of carcinomas with extensive bone destruction was observed commonly in the gingiva of dentulous maxillary jaws without functional occlusion, but was scarcely observed in the gingiva of edentulous jaws. By analogy, disuse atrophy of the periodontium due to loss of functional occlusion may result in early deeper invasion, while loss of periodontal ligament due to tooth extraction and disappearance of so-called inner gingival epithelium may result in less invasive carcinomas.</div>
</front>
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</record>
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