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Effect of hormone replacement therapy on salivary flow rate, buffer effect and ph in perimenopausal and postmenopausal

Identifieur interne : 00A888 ( Main/Merge ); précédent : 00A887; suivant : 00A889

Effect of hormone replacement therapy on salivary flow rate, buffer effect and ph in perimenopausal and postmenopausal

Auteurs : Women M. Laine [Finlande] ; R. Leimola-Virtanen [Finlande]

Source :

RBID : ISTEX:6B6A87A8E72445358D74E9B059D224A189E611FB

English descriptors

Abstract

Abstract: The effects of hormone replacement therapy (HRT) on salivary gland functions were examined in a longitudinal study. The flow rate, buffer effect and pH of paraffin-stimulated whole saliva were analysed in 8 perimenopausal and 19 postmenopausal women. The saliva samples were collected 1–2 days before as well as 3 and 5 months after the start of HRT. Salivary flow rates were higher (p < 0.033) in the perimenopausal than in the postmenopausal group. The flow rates increased significantly (p < 0.001) during HRT in both groups. Similarly, buffer effect and pH showed significant (p = 0.004andp = 0.009, respectively) time-related changes without any differences between the groups. It appears that HRT improves both the quantity and the quality of salivary gland function in peri- and postmenopausal women.

Url:
DOI: 10.1016/0003-9969(95)00085-2

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ISTEX:6B6A87A8E72445358D74E9B059D224A189E611FB

Le document en format XML

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<term>Beneficial effect</term>
<term>Blood flow</term>
<term>Buffer effect</term>
<term>Control group</term>
<term>Correlation coefficients</term>
<term>Estrogen</term>
<term>Flow rate</term>
<term>Flow rates</term>
<term>HRT</term>
<term>Hormonal status</term>
<term>Hormone replacement therapy</term>
<term>Leiras pharmaceuticals</term>
<term>Longitudinal study</term>
<term>Menopausal women</term>
<term>Menopause</term>
<term>Night sweats</term>
<term>Oestradiol valeriate</term>
<term>Oestrogen</term>
<term>Oestrogen action</term>
<term>Oral discomfort</term>
<term>Oral health</term>
<term>Oral pathol</term>
<term>Oral status</term>
<term>Oral surg</term>
<term>Perimenopausal</term>
<term>Perimenopausal group</term>
<term>Possible effect</term>
<term>Postmenopausal</term>
<term>Postmenopausal group</term>
<term>Postmenopausal women</term>
<term>Progesterone receptor</term>
<term>Receptor</term>
<term>Saliva samples</term>
<term>Salivary</term>
<term>Salivary albumin concentrations</term>
<term>Salivary flow rate</term>
<term>Salivary flow rates</term>
<term>Salivary gland function</term>
<term>Salivary glands</term>
<term>Secretion rate</term>
<term>Secretory rates</term>
<term>Specific oestrogen receptors</term>
<term>Statistical analyses</term>
<term>Steroid hormones</term>
<term>Subjective feeling</term>
<term>Target tissues</term>
<term>Third collection</term>
<term>Urogenital tract</term>
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<term>buffer effect</term>
<term>hormone replacement therapy</term>
<term>menopause</term>
<term>salivary flow rate</term>
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<term>Blood flow</term>
<term>Buffer effect</term>
<term>Control group</term>
<term>Correlation coefficients</term>
<term>Estrogen</term>
<term>Flow rate</term>
<term>Flow rates</term>
<term>Hormonal status</term>
<term>Hormone replacement therapy</term>
<term>Leiras pharmaceuticals</term>
<term>Longitudinal study</term>
<term>Menopausal women</term>
<term>Menopause</term>
<term>Night sweats</term>
<term>Oestradiol valeriate</term>
<term>Oestrogen</term>
<term>Oestrogen action</term>
<term>Oral discomfort</term>
<term>Oral health</term>
<term>Oral pathol</term>
<term>Oral status</term>
<term>Oral surg</term>
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<term>Perimenopausal group</term>
<term>Possible effect</term>
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<term>Postmenopausal group</term>
<term>Postmenopausal women</term>
<term>Progesterone receptor</term>
<term>Receptor</term>
<term>Saliva samples</term>
<term>Salivary</term>
<term>Salivary albumin concentrations</term>
<term>Salivary flow rate</term>
<term>Salivary flow rates</term>
<term>Salivary gland function</term>
<term>Salivary glands</term>
<term>Secretion rate</term>
<term>Secretory rates</term>
<term>Specific oestrogen receptors</term>
<term>Statistical analyses</term>
<term>Steroid hormones</term>
<term>Subjective feeling</term>
<term>Target tissues</term>
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<div type="abstract" xml:lang="en">Abstract: The effects of hormone replacement therapy (HRT) on salivary gland functions were examined in a longitudinal study. The flow rate, buffer effect and pH of paraffin-stimulated whole saliva were analysed in 8 perimenopausal and 19 postmenopausal women. The saliva samples were collected 1–2 days before as well as 3 and 5 months after the start of HRT. Salivary flow rates were higher (p < 0.033) in the perimenopausal than in the postmenopausal group. The flow rates increased significantly (p < 0.001) during HRT in both groups. Similarly, buffer effect and pH showed significant (p = 0.004andp = 0.009, respectively) time-related changes without any differences between the groups. It appears that HRT improves both the quantity and the quality of salivary gland function in peri- and postmenopausal women.</div>
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