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Oral lesions in organ transplant patients

Identifieur interne : 00A325 ( Main/Merge ); précédent : 00A324; suivant : 00A326

Oral lesions in organ transplant patients

Auteurs : Robin A. Seymour [Royaume-Uni] ; J. Mark Thomason [Royaume-Uni] ; A. Nolan [Royaume-Uni]

Source :

RBID : ISTEX:62B0CC8566C722758A5DAA21A6C360B80A2A17E8

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English descriptors

Abstract

Patients who have undergone organ transplantation can present with a variety of oral lesions that appear to be related either directly to their medication or arise as a consequence of drug‐induced immunosuppression. Such lesions include hairy leukoplakia, an increased propensity to both fungal and viral infections and a high incidence of malignant change, especially lip cancer. Cyciosporin remains the immunosuppressant of choice in most transplant patients. Gingival overgrowth is the main unwanted oral effect associated with cyclosporin. Some 30% of dentate transplant patients experience this problem, which is further compounded by concomitant medication with a calcium channel blocker. This review appraises the various oral problems that can arise in this group of patients and emphasises the importance of regular oral screening and the establishment of links with the various transplant teams.

Url:
DOI: 10.1111/j.1600-0714.1997.tb00219.x

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ISTEX:62B0CC8566C722758A5DAA21A6C360B80A2A17E8

Le document en format XML

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<term>Acyclovir</term>
<term>Allograft</term>
<term>Azathioprine</term>
<term>Bone marrow transplant patients</term>
<term>Candidosis</term>
<term>Carcinoma</term>
<term>Case reports</term>
<term>Clin</term>
<term>Clin periodontol</term>
<term>Cyclosporin</term>
<term>Cytomegalovirus</term>
<term>Cytomegalovirus infection</term>
<term>Gingival</term>
<term>Gingival hyperplasia</term>
<term>Gingival overgrowth</term>
<term>Gingival tissues</term>
<term>Greenspan</term>
<term>Hairy</term>
<term>Hairy leukoplakia</term>
<term>Heart transplant recipients</term>
<term>Herpes</term>
<term>Herpes simplex virus</term>
<term>Hyperplasia</term>
<term>Immunosuppressed organ transplant patients</term>
<term>Immunosuppression</term>
<term>Immunosuppressive</term>
<term>Immunosuppressive therapy</term>
<term>Infection</term>
<term>Kidney transplant recipients</term>
<term>Lateral border</term>
<term>Lesion</term>
<term>Leukoplakia</term>
<term>Lymphoma</term>
<term>Malignancy</term>
<term>Malignant</term>
<term>Medicated</term>
<term>Oral lesions</term>
<term>Oral pathol</term>
<term>Oral surg</term>
<term>Organ</term>
<term>Organ transplant</term>
<term>Organ transplant patients</term>
<term>Organ transplant recipients</term>
<term>Organ transplantation</term>
<term>Overgrowth</term>
<term>Pathogenesis</term>
<term>Pathol</term>
<term>Periodontal</term>
<term>Prednisolone</term>
<term>Prevalence</term>
<term>Renal</term>
<term>Renal transplant patient</term>
<term>Renal transplant patients</term>
<term>Renal transplant recipients</term>
<term>Renal transplantation</term>
<term>Renal transplants</term>
<term>Sarcoma</term>
<term>Seymour</term>
<term>Simplex</term>
<term>Surg</term>
<term>Thomason</term>
<term>Transplant</term>
<term>Transplant patients</term>
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<term>Transplantation</term>
<term>Various transplant teams</term>
<term>Viral infections</term>
<term>Whilst</term>
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<term>Allograft</term>
<term>Azathioprine</term>
<term>Bone marrow transplant patients</term>
<term>Candidosis</term>
<term>Carcinoma</term>
<term>Case reports</term>
<term>Clin</term>
<term>Clin periodontol</term>
<term>Cyclosporin</term>
<term>Cytomegalovirus</term>
<term>Cytomegalovirus infection</term>
<term>Gingival</term>
<term>Gingival hyperplasia</term>
<term>Gingival overgrowth</term>
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<term>Greenspan</term>
<term>Hairy</term>
<term>Hairy leukoplakia</term>
<term>Heart transplant recipients</term>
<term>Herpes</term>
<term>Herpes simplex virus</term>
<term>Hyperplasia</term>
<term>Immunosuppressed organ transplant patients</term>
<term>Immunosuppression</term>
<term>Immunosuppressive</term>
<term>Immunosuppressive therapy</term>
<term>Infection</term>
<term>Kidney transplant recipients</term>
<term>Lateral border</term>
<term>Lesion</term>
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<term>Lymphoma</term>
<term>Malignancy</term>
<term>Malignant</term>
<term>Medicated</term>
<term>Oral lesions</term>
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<term>Oral surg</term>
<term>Organ</term>
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<term>Organ transplant patients</term>
<term>Organ transplant recipients</term>
<term>Organ transplantation</term>
<term>Overgrowth</term>
<term>Pathogenesis</term>
<term>Pathol</term>
<term>Periodontal</term>
<term>Prednisolone</term>
<term>Prevalence</term>
<term>Renal</term>
<term>Renal transplant patient</term>
<term>Renal transplant patients</term>
<term>Renal transplant recipients</term>
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<div type="abstract" xml:lang="en">Patients who have undergone organ transplantation can present with a variety of oral lesions that appear to be related either directly to their medication or arise as a consequence of drug‐induced immunosuppression. Such lesions include hairy leukoplakia, an increased propensity to both fungal and viral infections and a high incidence of malignant change, especially lip cancer. Cyciosporin remains the immunosuppressant of choice in most transplant patients. Gingival overgrowth is the main unwanted oral effect associated with cyclosporin. Some 30% of dentate transplant patients experience this problem, which is further compounded by concomitant medication with a calcium channel blocker. This review appraises the various oral problems that can arise in this group of patients and emphasises the importance of regular oral screening and the establishment of links with the various transplant teams.</div>
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