The use of titanium implants and prosthodontic techniques in the preparation of non-human primates for long-term neuronal recording studies
Identifieur interne : 008B68 ( Main/Merge ); précédent : 008B67; suivant : 008B69The use of titanium implants and prosthodontic techniques in the preparation of non-human primates for long-term neuronal recording studies
Auteurs : K. F. Betelak [États-Unis] ; E. A. Margiotti [États-Unis] ; M. E. Wohlford [États-Unis] ; D. A. Suzuki [États-Unis]Source :
- Journal of Neuroscience Methods [ 0165-0270 ] ; 2001.
Descripteurs français
- Wicri :
- topic : Titane.
English descriptors
- KwdEn :
- Abutment, Acrylic resin, Albrektsson, Anchor screws, Ange, Ange surface, Behavioral paradigms, Betelak, Bone biology, Bone growth, Bone tissue, Branemark, Branemark zarb, Brous, Brous tissue, Brous tissue layer, Clinical dentistry, Delrin plug, Dental laboratory procedures, Dental lathe, Dentistry, Dentsply, Denture, Direct contact, Endosseous, Endosseous implant, External threads, Functional anchor points, Head implant, Head implant failures, Head implant integrity, Head implants, Healing period, Implant, Implantation, Impression material, Infectious organisms, Lamellar bone, Load duration, Macaque, Macaque skull, Model stone, Nemestrina, Neuronal, Neuronal recording, Neuroscience, Neuroscience methods, Nobel biocare, Non-human primate, Osseointegrated, Osseointegrated implants, Osseointegration, Osteogenic tissue, Pilot hole, Primate, Primate skull, Primates, Quintessence, Quintessence publishing, Recording chamber, Rudd, Skull, Skull impression, Skull stone, Skull surface, Skull-anchored implant, Soft tissue, Soft tissues, Stable head implants, Stereotaxic, Stereotaxic frame, Sterile saline, Surgical, Surgical preparation, Titanium, Titanium endosseous implants, Titanium implant, Titanium implants, Tjellstrom, Training period, Transverse cylinders, Xture, Xture holes, Xture site, Xtures, Zarb.
- Teeft :
- Abutment, Acrylic resin, Albrektsson, Anchor screws, Ange, Ange surface, Behavioral paradigms, Betelak, Bone growth, Bone tissue, Branemark, Branemark zarb, Brous, Brous tissue, Brous tissue layer, Clinical dentistry, Delrin plug, Dental laboratory procedures, Dental lathe, Dentistry, Dentsply, Denture, Direct contact, Endosseous, Endosseous implant, External threads, Functional anchor points, Head implant, Head implant failures, Head implant integrity, Head implants, Healing period, Implant, Implantation, Impression material, Infectious organisms, Lamellar bone, Load duration, Macaque, Macaque skull, Model stone, Nemestrina, Neuronal, Neuronal recording, Neuroscience, Neuroscience methods, Nobel biocare, Osseointegrated, Osseointegrated implants, Osseointegration, Osteogenic tissue, Pilot hole, Primate, Primate skull, Primates, Quintessence, Quintessence publishing, Recording chamber, Rudd, Skull, Skull impression, Skull stone, Skull surface, Soft tissue, Soft tissues, Stable head implants, Stereotaxic, Stereotaxic frame, Sterile saline, Surgical, Surgical preparation, Titanium, Titanium endosseous implants, Titanium implants, Tjellstrom, Training period, Transverse cylinders, Xture, Xture holes, Xture site, Xtures, Zarb.
Abstract
Abstract: Investigators that require the chronic implantation of hardware on the non-human primate skull are often challenged with the possible failure of head implants. To improve the success rate of our head implants, titanium anchor screws, referred to as titanium endosseous implants, were implanted in the skulls of six macaques. Techniques adapted from the processing of dentures were utilized to pre-fabricate an acrylic ‘skull cap’, which provided the mechanical support structure for our study-specific hardware. A two-stage procedure adapted from dentistry (Brånemark et al., 1977) was employed for the placement of titanium endosseous implants in the skull. This two-stage technique incorporates the principles of osseointegration and a healing period. Of the six skull-anchored implants prepared implementing the methods described in this paper, we have not experienced any failures. Additionally, all of the titanium endosseous implants examined post mortem were functionally successful (n=30). Histology results confirmed that there was healthy bone in direct contact with the titanium endosseous implants. The dense cortical bone of the macaque skull is ideal for the implantation of titanium endosseous implants. Titanium endosseous implants have provided secure, functional anchor points for the attachment of hardware to the macaque skull and have resulted in healthy, stable head implants that can remain on the skull for extended periods of time.
Url:
DOI: 10.1016/S0165-0270(01)00442-3
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<term>Anchor screws</term>
<term>Ange</term>
<term>Ange surface</term>
<term>Behavioral paradigms</term>
<term>Betelak</term>
<term>Bone biology</term>
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<term>Branemark</term>
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<term>Brous</term>
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<term>Denture</term>
<term>Direct contact</term>
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<term>Endosseous implant</term>
<term>External threads</term>
<term>Functional anchor points</term>
<term>Head implant</term>
<term>Head implant failures</term>
<term>Head implant integrity</term>
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<term>Implantation</term>
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<term>Infectious organisms</term>
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<term>Load duration</term>
<term>Macaque</term>
<term>Macaque skull</term>
<term>Model stone</term>
<term>Nemestrina</term>
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<term>Neuronal recording</term>
<term>Neuroscience</term>
<term>Neuroscience methods</term>
<term>Nobel biocare</term>
<term>Non-human primate</term>
<term>Osseointegrated</term>
<term>Osseointegrated implants</term>
<term>Osseointegration</term>
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<term>Pilot hole</term>
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<term>Primate skull</term>
<term>Primates</term>
<term>Quintessence</term>
<term>Quintessence publishing</term>
<term>Recording chamber</term>
<term>Rudd</term>
<term>Skull</term>
<term>Skull impression</term>
<term>Skull stone</term>
<term>Skull surface</term>
<term>Skull-anchored implant</term>
<term>Soft tissue</term>
<term>Soft tissues</term>
<term>Stable head implants</term>
<term>Stereotaxic</term>
<term>Stereotaxic frame</term>
<term>Sterile saline</term>
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<term>Surgical preparation</term>
<term>Titanium</term>
<term>Titanium endosseous implants</term>
<term>Titanium implant</term>
<term>Titanium implants</term>
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<term>Ange surface</term>
<term>Behavioral paradigms</term>
<term>Betelak</term>
<term>Bone growth</term>
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<term>External threads</term>
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<term>Osseointegrated implants</term>
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<term>Surgical preparation</term>
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<front><div type="abstract" xml:lang="en">Abstract: Investigators that require the chronic implantation of hardware on the non-human primate skull are often challenged with the possible failure of head implants. To improve the success rate of our head implants, titanium anchor screws, referred to as titanium endosseous implants, were implanted in the skulls of six macaques. Techniques adapted from the processing of dentures were utilized to pre-fabricate an acrylic ‘skull cap’, which provided the mechanical support structure for our study-specific hardware. A two-stage procedure adapted from dentistry (Brånemark et al., 1977) was employed for the placement of titanium endosseous implants in the skull. This two-stage technique incorporates the principles of osseointegration and a healing period. Of the six skull-anchored implants prepared implementing the methods described in this paper, we have not experienced any failures. Additionally, all of the titanium endosseous implants examined post mortem were functionally successful (n=30). Histology results confirmed that there was healthy bone in direct contact with the titanium endosseous implants. The dense cortical bone of the macaque skull is ideal for the implantation of titanium endosseous implants. Titanium endosseous implants have provided secure, functional anchor points for the attachment of hardware to the macaque skull and have resulted in healthy, stable head implants that can remain on the skull for extended periods of time.</div>
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