Effects of adhesion molecules on the behavior of osteoblast‐like cells and normal human fibroblasts on different titanium surfaces
Identifieur interne : 007671 ( Main/Merge ); précédent : 007670; suivant : 007672Effects of adhesion molecules on the behavior of osteoblast‐like cells and normal human fibroblasts on different titanium surfaces
Auteurs : Beom Seok Park [Corée du Sud] ; Seong Joo Heo [Corée du Sud] ; Chul Sang Kim [Corée du Sud] ; Ju-Eun Oh [Corée du Sud] ; Jin-Man Kim [Corée du Sud] ; Gene Lee [Corée du Sud] ; Won Ho Park [Corée du Sud] ; Chong-Pyoung Chung [Corée du Sud] ; Byung-Moo Min [Corée du Sud]Source :
- Journal of Biomedical Materials Research Part A [ 1549-3296 ] ; 2005-09-15.
Descripteurs français
- Wicri :
- topic : Biomatériau, Titane.
English descriptors
- KwdEn :
- Absolute values, Adherent cells, Adhesion, Adhesion molecules, Adhesion titanium surfaces, Adsorption, Alkaline phosphatase, Assay, Auger electron transitions, Biol chem, Biomaterials, Biomaterials science, Biomed, Biomed mater, Bone cells, Broblasts, Bronectin, Bronectin conformation, Cacodylate buffer, Calcium phosphate, Calvarial osteoblasts, Cell adhesion, Cell attachment, Cell behaviors, Cell growth, Cell suspension, Cellular response, Chemical composition, Chemical compositions, Collagen, Collagen coating, Collagen immobilization, Compositional variations, Control plastic dishes, Crystal violet, Culture medium, Culture plate, Culture plates, Dental implants, Dental research institute, Different surfaces, Different topographies, Different types, Disc, Disc surfaces, Disc types, Extracellular matrix, Good candidate, Heat treatment, Human plasma, Implant, Implant material, Implant materials, Implant surface, Implant surfaces, Important role, Independent experiments, Inhibition assay, Initial behavior, Integrin, Integrin binding, Integrin interaction, Integrin subunits, Integrins, Kinetic energies, Mater, Matrix, Matrix molecules, Monoclonal antibodies, Nhgf, Nonspreading cells, Optical interferometer, Oral maxillofac implants, Osteoblast, Osteoblast phenotype, Osteoblast responses, Osteoblastic, Osteoblastic cells, Osteoblastic differentiation, Osteoblastlike cells, Other type, Overnight adsorption, Pairwise comparisons, Phase transition temperature, Plate surface, Polygonal shape, Polystyrene, Polystyrene surface, Protective argon atmosphere, Receptor, Representative count, Rinsed, Saes depth, Scanning auger electron spectroscopy, Scanning electron microscopy, Seoul, Seoul korea, Subunit, Surface departures, Surface engineering, Surface roughness, Surface topography, Titanium, Titanium implants, Unattached cells, Uncoated, Uncoated counterparts, Uncoated surfaces, Wiley periodicals.
- Teeft :
- Absolute values, Adherent cells, Adhesion, Adhesion molecules, Adhesion titanium surfaces, Adsorption, Alkaline phosphatase, Assay, Auger electron transitions, Biol chem, Biomaterials, Biomaterials science, Biomed, Biomed mater, Bone cells, Broblasts, Bronectin, Bronectin conformation, Cacodylate buffer, Calcium phosphate, Calvarial osteoblasts, Cell adhesion, Cell attachment, Cell behaviors, Cell growth, Cell suspension, Cellular response, Chemical composition, Chemical compositions, Collagen, Collagen coating, Collagen immobilization, Compositional variations, Control plastic dishes, Crystal violet, Culture medium, Culture plate, Culture plates, Dental implants, Dental research institute, Different surfaces, Different topographies, Different types, Disc, Disc surfaces, Disc types, Extracellular matrix, Good candidate, Heat treatment, Human plasma, Implant, Implant material, Implant materials, Implant surface, Implant surfaces, Important role, Independent experiments, Inhibition assay, Initial behavior, Integrin, Integrin binding, Integrin interaction, Integrin subunits, Integrins, Kinetic energies, Mater, Matrix, Matrix molecules, Monoclonal antibodies, Nhgf, Nonspreading cells, Optical interferometer, Oral maxillofac implants, Osteoblast, Osteoblast phenotype, Osteoblast responses, Osteoblastic, Osteoblastic cells, Osteoblastic differentiation, Osteoblastlike cells, Other type, Overnight adsorption, Pairwise comparisons, Phase transition temperature, Plate surface, Polygonal shape, Polystyrene, Polystyrene surface, Protective argon atmosphere, Receptor, Representative count, Rinsed, Saes depth, Scanning auger electron spectroscopy, Scanning electron microscopy, Seoul, Seoul korea, Subunit, Surface departures, Surface engineering, Surface roughness, Surface topography, Titanium, Titanium implants, Unattached cells, Uncoated, Uncoated counterparts, Uncoated surfaces, Wiley periodicals.
Abstract
This study examined the influences of titanium (Ti) discs with similar surface roughnesses (Ra values), but with different topographies and chemical compositions, on the adhesion, spreading, and the alkaline phosphatase (ALP) activity of osteoblast‐like cells and normal human fibroblasts. The presence of adhesion molecules on the Ti surfaces and their effects on cell activity were also investigated. Two types of Ti discs were prepared. One kind was a mechanically polished Ti disc, and the other type was a disc obtained by the heating of hydroxyapatite (HA) dip‐coated Ti. Scanning electron microscopy, optical interferometry, and scanning Auger electron spectroscopy were used to examine the surface morphology, roughness, and chemical composition, respectively, of the superficial Ti layer. The two types of Ti discs had different topographies and chemical compositions, but had similar Ra values. The cells on both surface types had similar behaviors and ALP activities. A biological evaluation of the surface‐modified Ti discs showed that the type I collagen coating was functionally active in terms of cell spreading in both types of Ti discs. In the mechanically polished Ti discs, fibronectin was functionally active in the normal human fibroblasts, but not in the osteoblast‐like cells. Cell adhesion was slightly better on the heat‐treated HA dip‐coated Ti discs, but not on the mechanically polished Ti discs. Type I collagen and fibronectin mediated the adhesion and spreading of osteoblast‐like cells through α2β1 integrin and α5β1 integrin, respectively. These results suggest that type I collagen might be a good candidate for the biochemical modification of Ti surfaces, particularly those surfaces obtained by heating of HA dip‐coated Ti. © 2005 Wiley Periodicals, Inc. J Biomed Mater Res, 2005
Url:
DOI: 10.1002/jbm.a.30326
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 005C76
- to stream Istex, to step Curation: 005C76
- to stream Istex, to step Checkpoint: 003010
Links to Exploration step
ISTEX:BA54A984C9723F1C97990920DD90DBFEE93FF59CLe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Effects of adhesion molecules on the behavior of osteoblast‐like cells and normal human fibroblasts on different titanium surfaces</title>
<author><name sortKey="Park, Beom Seok" sort="Park, Beom Seok" uniqKey="Park B" first="Beom Seok" last="Park">Beom Seok Park</name>
</author>
<author><name sortKey="Heo, Seong Joo" sort="Heo, Seong Joo" uniqKey="Heo S" first="Seong Joo" last="Heo">Seong Joo Heo</name>
</author>
<author><name sortKey="Kim, Chul Sang" sort="Kim, Chul Sang" uniqKey="Kim C" first="Chul Sang" last="Kim">Chul Sang Kim</name>
</author>
<author><name sortKey="Oh, Ju Un" sort="Oh, Ju Un" uniqKey="Oh J" first="Ju-Eun" last="Oh">Ju-Eun Oh</name>
</author>
<author><name sortKey="Kim, Jin An" sort="Kim, Jin An" uniqKey="Kim J" first="Jin-Man" last="Kim">Jin-Man Kim</name>
</author>
<author><name sortKey="Lee, Gene" sort="Lee, Gene" uniqKey="Lee G" first="Gene" last="Lee">Gene Lee</name>
</author>
<author><name sortKey="Park, Won Ho" sort="Park, Won Ho" uniqKey="Park W" first="Won Ho" last="Park">Won Ho Park</name>
</author>
<author><name sortKey="Chung, Chong Young" sort="Chung, Chong Young" uniqKey="Chung C" first="Chong-Pyoung" last="Chung">Chong-Pyoung Chung</name>
</author>
<author><name sortKey="Min, Byung Oo" sort="Min, Byung Oo" uniqKey="Min B" first="Byung-Moo" last="Min">Byung-Moo Min</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:BA54A984C9723F1C97990920DD90DBFEE93FF59C</idno>
<date when="2005" year="2005">2005</date>
<idno type="doi">10.1002/jbm.a.30326</idno>
<idno type="url">https://api.istex.fr/document/BA54A984C9723F1C97990920DD90DBFEE93FF59C/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">005C76</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">005C76</idno>
<idno type="wicri:Area/Istex/Curation">005C76</idno>
<idno type="wicri:Area/Istex/Checkpoint">003010</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">003010</idno>
<idno type="wicri:doubleKey">1549-3296:2005:Park B:effects:of:adhesion</idno>
<idno type="wicri:Area/Main/Merge">007671</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Effects of adhesion molecules on the behavior of osteoblast‐like cells and normal human fibroblasts on different titanium surfaces</title>
<author><name sortKey="Park, Beom Seok" sort="Park, Beom Seok" uniqKey="Park B" first="Beom Seok" last="Park">Beom Seok Park</name>
<affiliation wicri:level="4"><country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Department of Oral Biochemistry, BK21 HLS, and Dental Research Institute, College of Dentistry, Seoul National University, Seoul 110‐749</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
<settlement type="city">Séoul</settlement>
</placeName>
<orgName type="university">Université nationale de Séoul</orgName>
</affiliation>
</author>
<author><name sortKey="Heo, Seong Joo" sort="Heo, Seong Joo" uniqKey="Heo S" first="Seong Joo" last="Heo">Seong Joo Heo</name>
<affiliation wicri:level="4"><country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Department of Prosthodontics, BK21 HLS, and Dental Research Institute, College of Dentistry, Seoul National University, Seoul 110‐749</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
<settlement type="city">Séoul</settlement>
</placeName>
<orgName type="university">Université nationale de Séoul</orgName>
</affiliation>
</author>
<author><name sortKey="Kim, Chul Sang" sort="Kim, Chul Sang" uniqKey="Kim C" first="Chul Sang" last="Kim">Chul Sang Kim</name>
<affiliation wicri:level="1"><country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Division of Electronics and Information Engineering, Chonbuk National University, Jeonju, Chonbuk</wicri:regionArea>
<wicri:noRegion>Chonbuk</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Oh, Ju Un" sort="Oh, Ju Un" uniqKey="Oh J" first="Ju-Eun" last="Oh">Ju-Eun Oh</name>
<affiliation wicri:level="4"><country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Department of Oral Biochemistry, BK21 HLS, and Dental Research Institute, College of Dentistry, Seoul National University, Seoul 110‐749</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
<settlement type="city">Séoul</settlement>
</placeName>
<orgName type="university">Université nationale de Séoul</orgName>
</affiliation>
<affiliation wicri:level="4"><country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Intellectual Biointerface Engineering Center, Seoul National University, Seoul 110‐749</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
<settlement type="city">Séoul</settlement>
</placeName>
<orgName type="university">Université nationale de Séoul</orgName>
</affiliation>
</author>
<author><name sortKey="Kim, Jin An" sort="Kim, Jin An" uniqKey="Kim J" first="Jin-Man" last="Kim">Jin-Man Kim</name>
<affiliation wicri:level="4"><country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Department of Oral Biochemistry, BK21 HLS, and Dental Research Institute, College of Dentistry, Seoul National University, Seoul 110‐749</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
<settlement type="city">Séoul</settlement>
</placeName>
<orgName type="university">Université nationale de Séoul</orgName>
</affiliation>
<affiliation wicri:level="4"><country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Intellectual Biointerface Engineering Center, Seoul National University, Seoul 110‐749</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
<settlement type="city">Séoul</settlement>
</placeName>
<orgName type="university">Université nationale de Séoul</orgName>
</affiliation>
</author>
<author><name sortKey="Lee, Gene" sort="Lee, Gene" uniqKey="Lee G" first="Gene" last="Lee">Gene Lee</name>
<affiliation wicri:level="4"><country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Department of Oral Biochemistry, BK21 HLS, and Dental Research Institute, College of Dentistry, Seoul National University, Seoul 110‐749</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
<settlement type="city">Séoul</settlement>
</placeName>
<orgName type="university">Université nationale de Séoul</orgName>
</affiliation>
</author>
<author><name sortKey="Park, Won Ho" sort="Park, Won Ho" uniqKey="Park W" first="Won Ho" last="Park">Won Ho Park</name>
<affiliation wicri:level="4"><country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Intellectual Biointerface Engineering Center, Seoul National University, Seoul 110‐749</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
<settlement type="city">Séoul</settlement>
</placeName>
<orgName type="university">Université nationale de Séoul</orgName>
</affiliation>
<affiliation wicri:level="1"><country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Department of Textile Engineering, Chungnam National University, Daejeon 305‐764</wicri:regionArea>
<wicri:noRegion>Daejeon 305‐764</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chung, Chong Young" sort="Chung, Chong Young" uniqKey="Chung C" first="Chong-Pyoung" last="Chung">Chong-Pyoung Chung</name>
<affiliation wicri:level="4"><country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Intellectual Biointerface Engineering Center, Seoul National University, Seoul 110‐749</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
<settlement type="city">Séoul</settlement>
</placeName>
<orgName type="university">Université nationale de Séoul</orgName>
</affiliation>
<affiliation wicri:level="4"><country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Department of Periodontology, BK21 HLS, and Dental Research Institute, College of Dentistry, Seoul National University, Seoul 110‐749</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
<settlement type="city">Séoul</settlement>
</placeName>
<orgName type="university">Université nationale de Séoul</orgName>
</affiliation>
</author>
<author><name sortKey="Min, Byung Oo" sort="Min, Byung Oo" uniqKey="Min B" first="Byung-Moo" last="Min">Byung-Moo Min</name>
<affiliation wicri:level="4"><country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Department of Oral Biochemistry, BK21 HLS, and Dental Research Institute, College of Dentistry, Seoul National University, Seoul 110‐749</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
<settlement type="city">Séoul</settlement>
</placeName>
<orgName type="university">Université nationale de Séoul</orgName>
</affiliation>
<affiliation wicri:level="4"><country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Intellectual Biointerface Engineering Center, Seoul National University, Seoul 110‐749</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
<settlement type="city">Séoul</settlement>
</placeName>
<orgName type="university">Université nationale de Séoul</orgName>
</affiliation>
<affiliation wicri:level="1"><country wicri:rule="url">Corée du Sud</country>
</affiliation>
<affiliation wicri:level="4"><country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Correspondence address: Department of Oral Biochemistry, BK21 HLS, and Dental Research Institute, College of Dentistry, Seoul National University, Seoul 110‐749</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
<settlement type="city">Séoul</settlement>
</placeName>
<orgName type="university">Université nationale de Séoul</orgName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j" type="main">Journal of Biomedical Materials Research Part A</title>
<title level="j" type="alt">JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A</title>
<idno type="ISSN">1549-3296</idno>
<idno type="eISSN">1552-4965</idno>
<imprint><biblScope unit="vol">74A</biblScope>
<biblScope unit="issue">4</biblScope>
<biblScope unit="page" from="640">640</biblScope>
<biblScope unit="page" to="651">651</biblScope>
<biblScope unit="page-count">12</biblScope>
<publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>Hoboken</pubPlace>
<date type="published" when="2005-09-15">2005-09-15</date>
</imprint>
<idno type="ISSN">1549-3296</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">1549-3296</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Absolute values</term>
<term>Adherent cells</term>
<term>Adhesion</term>
<term>Adhesion molecules</term>
<term>Adhesion titanium surfaces</term>
<term>Adsorption</term>
<term>Alkaline phosphatase</term>
<term>Assay</term>
<term>Auger electron transitions</term>
<term>Biol chem</term>
<term>Biomaterials</term>
<term>Biomaterials science</term>
<term>Biomed</term>
<term>Biomed mater</term>
<term>Bone cells</term>
<term>Broblasts</term>
<term>Bronectin</term>
<term>Bronectin conformation</term>
<term>Cacodylate buffer</term>
<term>Calcium phosphate</term>
<term>Calvarial osteoblasts</term>
<term>Cell adhesion</term>
<term>Cell attachment</term>
<term>Cell behaviors</term>
<term>Cell growth</term>
<term>Cell suspension</term>
<term>Cellular response</term>
<term>Chemical composition</term>
<term>Chemical compositions</term>
<term>Collagen</term>
<term>Collagen coating</term>
<term>Collagen immobilization</term>
<term>Compositional variations</term>
<term>Control plastic dishes</term>
<term>Crystal violet</term>
<term>Culture medium</term>
<term>Culture plate</term>
<term>Culture plates</term>
<term>Dental implants</term>
<term>Dental research institute</term>
<term>Different surfaces</term>
<term>Different topographies</term>
<term>Different types</term>
<term>Disc</term>
<term>Disc surfaces</term>
<term>Disc types</term>
<term>Extracellular matrix</term>
<term>Good candidate</term>
<term>Heat treatment</term>
<term>Human plasma</term>
<term>Implant</term>
<term>Implant material</term>
<term>Implant materials</term>
<term>Implant surface</term>
<term>Implant surfaces</term>
<term>Important role</term>
<term>Independent experiments</term>
<term>Inhibition assay</term>
<term>Initial behavior</term>
<term>Integrin</term>
<term>Integrin binding</term>
<term>Integrin interaction</term>
<term>Integrin subunits</term>
<term>Integrins</term>
<term>Kinetic energies</term>
<term>Mater</term>
<term>Matrix</term>
<term>Matrix molecules</term>
<term>Monoclonal antibodies</term>
<term>Nhgf</term>
<term>Nonspreading cells</term>
<term>Optical interferometer</term>
<term>Oral maxillofac implants</term>
<term>Osteoblast</term>
<term>Osteoblast phenotype</term>
<term>Osteoblast responses</term>
<term>Osteoblastic</term>
<term>Osteoblastic cells</term>
<term>Osteoblastic differentiation</term>
<term>Osteoblastlike cells</term>
<term>Other type</term>
<term>Overnight adsorption</term>
<term>Pairwise comparisons</term>
<term>Phase transition temperature</term>
<term>Plate surface</term>
<term>Polygonal shape</term>
<term>Polystyrene</term>
<term>Polystyrene surface</term>
<term>Protective argon atmosphere</term>
<term>Receptor</term>
<term>Representative count</term>
<term>Rinsed</term>
<term>Saes depth</term>
<term>Scanning auger electron spectroscopy</term>
<term>Scanning electron microscopy</term>
<term>Seoul</term>
<term>Seoul korea</term>
<term>Subunit</term>
<term>Surface departures</term>
<term>Surface engineering</term>
<term>Surface roughness</term>
<term>Surface topography</term>
<term>Titanium</term>
<term>Titanium implants</term>
<term>Unattached cells</term>
<term>Uncoated</term>
<term>Uncoated counterparts</term>
<term>Uncoated surfaces</term>
<term>Wiley periodicals</term>
</keywords>
<keywords scheme="Teeft" xml:lang="en"><term>Absolute values</term>
<term>Adherent cells</term>
<term>Adhesion</term>
<term>Adhesion molecules</term>
<term>Adhesion titanium surfaces</term>
<term>Adsorption</term>
<term>Alkaline phosphatase</term>
<term>Assay</term>
<term>Auger electron transitions</term>
<term>Biol chem</term>
<term>Biomaterials</term>
<term>Biomaterials science</term>
<term>Biomed</term>
<term>Biomed mater</term>
<term>Bone cells</term>
<term>Broblasts</term>
<term>Bronectin</term>
<term>Bronectin conformation</term>
<term>Cacodylate buffer</term>
<term>Calcium phosphate</term>
<term>Calvarial osteoblasts</term>
<term>Cell adhesion</term>
<term>Cell attachment</term>
<term>Cell behaviors</term>
<term>Cell growth</term>
<term>Cell suspension</term>
<term>Cellular response</term>
<term>Chemical composition</term>
<term>Chemical compositions</term>
<term>Collagen</term>
<term>Collagen coating</term>
<term>Collagen immobilization</term>
<term>Compositional variations</term>
<term>Control plastic dishes</term>
<term>Crystal violet</term>
<term>Culture medium</term>
<term>Culture plate</term>
<term>Culture plates</term>
<term>Dental implants</term>
<term>Dental research institute</term>
<term>Different surfaces</term>
<term>Different topographies</term>
<term>Different types</term>
<term>Disc</term>
<term>Disc surfaces</term>
<term>Disc types</term>
<term>Extracellular matrix</term>
<term>Good candidate</term>
<term>Heat treatment</term>
<term>Human plasma</term>
<term>Implant</term>
<term>Implant material</term>
<term>Implant materials</term>
<term>Implant surface</term>
<term>Implant surfaces</term>
<term>Important role</term>
<term>Independent experiments</term>
<term>Inhibition assay</term>
<term>Initial behavior</term>
<term>Integrin</term>
<term>Integrin binding</term>
<term>Integrin interaction</term>
<term>Integrin subunits</term>
<term>Integrins</term>
<term>Kinetic energies</term>
<term>Mater</term>
<term>Matrix</term>
<term>Matrix molecules</term>
<term>Monoclonal antibodies</term>
<term>Nhgf</term>
<term>Nonspreading cells</term>
<term>Optical interferometer</term>
<term>Oral maxillofac implants</term>
<term>Osteoblast</term>
<term>Osteoblast phenotype</term>
<term>Osteoblast responses</term>
<term>Osteoblastic</term>
<term>Osteoblastic cells</term>
<term>Osteoblastic differentiation</term>
<term>Osteoblastlike cells</term>
<term>Other type</term>
<term>Overnight adsorption</term>
<term>Pairwise comparisons</term>
<term>Phase transition temperature</term>
<term>Plate surface</term>
<term>Polygonal shape</term>
<term>Polystyrene</term>
<term>Polystyrene surface</term>
<term>Protective argon atmosphere</term>
<term>Receptor</term>
<term>Representative count</term>
<term>Rinsed</term>
<term>Saes depth</term>
<term>Scanning auger electron spectroscopy</term>
<term>Scanning electron microscopy</term>
<term>Seoul</term>
<term>Seoul korea</term>
<term>Subunit</term>
<term>Surface departures</term>
<term>Surface engineering</term>
<term>Surface roughness</term>
<term>Surface topography</term>
<term>Titanium</term>
<term>Titanium implants</term>
<term>Unattached cells</term>
<term>Uncoated</term>
<term>Uncoated counterparts</term>
<term>Uncoated surfaces</term>
<term>Wiley periodicals</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Biomatériau</term>
<term>Titane</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">This study examined the influences of titanium (Ti) discs with similar surface roughnesses (Ra values), but with different topographies and chemical compositions, on the adhesion, spreading, and the alkaline phosphatase (ALP) activity of osteoblast‐like cells and normal human fibroblasts. The presence of adhesion molecules on the Ti surfaces and their effects on cell activity were also investigated. Two types of Ti discs were prepared. One kind was a mechanically polished Ti disc, and the other type was a disc obtained by the heating of hydroxyapatite (HA) dip‐coated Ti. Scanning electron microscopy, optical interferometry, and scanning Auger electron spectroscopy were used to examine the surface morphology, roughness, and chemical composition, respectively, of the superficial Ti layer. The two types of Ti discs had different topographies and chemical compositions, but had similar Ra values. The cells on both surface types had similar behaviors and ALP activities. A biological evaluation of the surface‐modified Ti discs showed that the type I collagen coating was functionally active in terms of cell spreading in both types of Ti discs. In the mechanically polished Ti discs, fibronectin was functionally active in the normal human fibroblasts, but not in the osteoblast‐like cells. Cell adhesion was slightly better on the heat‐treated HA dip‐coated Ti discs, but not on the mechanically polished Ti discs. Type I collagen and fibronectin mediated the adhesion and spreading of osteoblast‐like cells through α2β1 integrin and α5β1 integrin, respectively. These results suggest that type I collagen might be a good candidate for the biochemical modification of Ti surfaces, particularly those surfaces obtained by heating of HA dip‐coated Ti. © 2005 Wiley Periodicals, Inc. J Biomed Mater Res, 2005</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 007671 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 007671 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= EdenteV2 |flux= Main |étape= Merge |type= RBID |clé= ISTEX:BA54A984C9723F1C97990920DD90DBFEE93FF59C |texte= Effects of adhesion molecules on the behavior of osteoblast‐like cells and normal human fibroblasts on different titanium surfaces }}
![]() | This area was generated with Dilib version V0.6.32. | ![]() |