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Osteonecrosis of the Mandible or Maxilla Associated with the use of New Generation Bisphosphonates

Identifieur interne : 007006 ( Main/Merge ); précédent : 007005; suivant : 007007

Osteonecrosis of the Mandible or Maxilla Associated with the use of New Generation Bisphosphonates

Auteurs : Matthew C. Farrugia [États-Unis] ; Don-John Summerlin [États-Unis] ; Edward Krowiak [États-Unis] ; Tod Huntley [États-Unis] ; Stephen Freeman [États-Unis] ; Richard Borrowdale [États-Unis] ; Charles Tomich [États-Unis]

Source :

The Laryngoscope [ 0023-852X ] ; 2006-01.

RBID : ISTEX:2E57D224B868BFDCC3C7D449EE7EB9A9CC06DEB8

English descriptors

Abstract

Objective: The use of bisphosphonates is well established for the treatment of patients with metastatic bone disease, osteoporosis, and Paget's disease. Osteonecrosis of the mandible or maxilla associated with the use of bisphosphonates is a newly described entity never before discussed in the otolaryngology literature. In this paper, we review a series of patients diagnosed with osteonecrosis, all treated with new generation bisphosphonates. Our objective is to inform and educate others, particularly otolaryngologists/head and neck surgeons, about this drug induced entity, a condition that should be recognized early to avoid potential devastating consequences.

Url:

https://api.istex.fr/document/2E57D224B868BFDCC3C7D449EE7EB9A9CC06DEB8/fulltext/pdf

DOI: 10.1097/01.mlg.0000187398.51857.3c

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ISTEX:2E57D224B868BFDCC3C7D449EE7EB9A9CC06DEB8

Le document en format XML

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<term>Alveolar ridge</term>
<term>American society</term>
<term>Aredia</term>
<term>Avascular</term>
<term>Avascular necrosis</term>
<term>Avascular process</term>
<term>Bisphosphonate</term>
<term>Bisphosphonate therapy</term>
<term>Bisphosphonates</term>
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<term>Bone resorption</term>
<term>Bone turnover</term>
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<term>Case report</term>
<term>Cellular level</term>
<term>Clin oncol</term>
<term>Clinical oncology</term>
<term>Clinical oncology bisphosphonates expert panel</term>
<term>Debridement</term>
<term>Dental procedures</term>
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<term>Farmington hills</term>
<term>Farrugia</term>
<term>Fosamax</term>
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<term>Hyperbaric oxygen</term>
<term>Intravenous</term>
<term>Intravenous bisphosphonates</term>
<term>Laryngoscope</term>
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<term>Mandible</term>
<term>Maxilla</term>
<term>Maxillary</term>
<term>Maxillary involvement</term>
<term>Maxillary sinus</term>
<term>Maxillofac</term>
<term>Medical history</term>
<term>Metastasis</term>
<term>Metastatic</term>
<term>Metastatic bone disease</term>
<term>Metastatic disease</term>
<term>Metastatic tumors</term>
<term>Multiple myeloma</term>
<term>Myeloma</term>
<term>Necrotic</term>
<term>Necrotic bone</term>
<term>Nitrogen side chain</term>
<term>Oral bisphosphonates</term>
<term>Oral hygiene</term>
<term>Oral maxillofac surg</term>
<term>Oral therapy</term>
<term>Osteoclast function</term>
<term>Osteonecrosis</term>
<term>Osteoporosis</term>
<term>Previous history</term>
<term>Prophylactic care</term>
<term>Radiation therapy</term>
<term>Surg</term>
<term>Tomography scan</term>
<term>Total maxillectomy</term>
<term>Zometa</term>
<term>Zometa mandible</term>
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<term>Avascular necrosis</term>
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<term>Bisphosphonates</term>
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<term>Bone resorption</term>
<term>Bone turnover</term>
<term>Breast cancer</term>
<term>Case report</term>
<term>Cellular level</term>
<term>Clin oncol</term>
<term>Clinical oncology</term>
<term>Clinical oncology bisphosphonates expert panel</term>
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<term>Dental procedures</term>
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<term>Effective treatment</term>
<term>Farmington hills</term>
<term>Farrugia</term>
<term>Fosamax</term>
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<term>Metastatic bone disease</term>
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<term>Osteoporosis</term>
<term>Previous history</term>
<term>Prophylactic care</term>
<term>Radiation therapy</term>
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<front><div type="abstract">Objective: The use of bisphosphonates is well established for the treatment of patients with metastatic bone disease, osteoporosis, and Paget's disease. Osteonecrosis of the mandible or maxilla associated with the use of bisphosphonates is a newly described entity never before discussed in the otolaryngology literature. In this paper, we review a series of patients diagnosed with osteonecrosis, all treated with new generation bisphosphonates. Our objective is to inform and educate others, particularly otolaryngologists/head and neck surgeons, about this drug induced entity, a condition that should be recognized early to avoid potential devastating consequences.</div>
</front>
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Osteonecrosis of the Mandible or Maxilla Associated with the use of New Generation Bisphosphonates

Osteonecrosis of the Mandible or Maxilla Associated with the use of New Generation Bisphosphonates

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English descriptors

Abstract

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