Osteonecrosis of the Mandible or Maxilla Associated with the use of New Generation Bisphosphonates
Identifieur interne : 007006 ( Main/Merge ); précédent : 007005; suivant : 007007Osteonecrosis of the Mandible or Maxilla Associated with the use of New Generation Bisphosphonates
Auteurs : Matthew C. Farrugia [États-Unis] ; Don-John Summerlin [États-Unis] ; Edward Krowiak [États-Unis] ; Tod Huntley [États-Unis] ; Stephen Freeman [États-Unis] ; Richard Borrowdale [États-Unis] ; Charles Tomich [États-Unis]Source :
- The Laryngoscope [ 0023-852X ] ; 2006-01.
English descriptors
- KwdEn :
- Absolute correlation, Alveolar ridge, American society, Aredia, Avascular, Avascular necrosis, Avascular process, Bisphosphonate, Bisphosphonate therapy, Bisphosphonates, Bone metastases, Bone resorption, Bone turnover, Breast cancer, Case report, Cellular level, Clin oncol, Clinical oncology, Clinical oncology bisphosphonates expert panel, Debridement, Dental procedures, Dental status, Effective treatment, Farmington hills, Farrugia, Fosamax, Generation bisphosphonates, Hyperbaric oxygen, Intravenous, Intravenous bisphosphonates, Laryngoscope, Local debridement, Mandible, Maxilla, Maxillary, Maxillary involvement, Maxillary sinus, Maxillofac, Medical history, Metastasis, Metastatic, Metastatic bone disease, Metastatic disease, Metastatic tumors, Multiple myeloma, Myeloma, Necrotic, Necrotic bone, Nitrogen side chain, Oral bisphosphonates, Oral hygiene, Oral maxillofac surg, Oral therapy, Osteoclast function, Osteonecrosis, Osteoporosis, Previous history, Prophylactic care, Radiation therapy, Surg, Tomography scan, Total maxillectomy, Zometa, Zometa mandible.
- Teeft :
- Absolute correlation, Alveolar ridge, American society, Aredia, Avascular, Avascular necrosis, Avascular process, Bisphosphonate, Bisphosphonate therapy, Bisphosphonates, Bone metastases, Bone resorption, Bone turnover, Breast cancer, Case report, Cellular level, Clin oncol, Clinical oncology, Clinical oncology bisphosphonates expert panel, Debridement, Dental procedures, Dental status, Effective treatment, Farmington hills, Farrugia, Fosamax, Generation bisphosphonates, Hyperbaric oxygen, Intravenous, Intravenous bisphosphonates, Laryngoscope, Local debridement, Mandible, Maxilla, Maxillary, Maxillary involvement, Maxillary sinus, Maxillofac, Medical history, Metastasis, Metastatic, Metastatic bone disease, Metastatic disease, Metastatic tumors, Multiple myeloma, Myeloma, Necrotic, Necrotic bone, Nitrogen side chain, Oral bisphosphonates, Oral hygiene, Oral maxillofac surg, Oral therapy, Osteoclast function, Osteonecrosis, Osteoporosis, Previous history, Prophylactic care, Radiation therapy, Surg, Tomography scan, Total maxillectomy, Zometa, Zometa mandible.
Abstract
Objective: The use of bisphosphonates is well established for the treatment of patients with metastatic bone disease, osteoporosis, and Paget's disease. Osteonecrosis of the mandible or maxilla associated with the use of bisphosphonates is a newly described entity never before discussed in the otolaryngology literature. In this paper, we review a series of patients diagnosed with osteonecrosis, all treated with new generation bisphosphonates. Our objective is to inform and educate others, particularly otolaryngologists/head and neck surgeons, about this drug induced entity, a condition that should be recognized early to avoid potential devastating consequences.
Url:
DOI: 10.1097/01.mlg.0000187398.51857.3c
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<term>Aredia</term>
<term>Avascular</term>
<term>Avascular necrosis</term>
<term>Avascular process</term>
<term>Bisphosphonate</term>
<term>Bisphosphonate therapy</term>
<term>Bisphosphonates</term>
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<term>Case report</term>
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<term>Clinical oncology bisphosphonates expert panel</term>
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<term>Avascular necrosis</term>
<term>Avascular process</term>
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<term>Farmington hills</term>
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<term>Prophylactic care</term>
<term>Radiation therapy</term>
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<front><div type="abstract">Objective: The use of bisphosphonates is well established for the treatment of patients with metastatic bone disease, osteoporosis, and Paget's disease. Osteonecrosis of the mandible or maxilla associated with the use of bisphosphonates is a newly described entity never before discussed in the otolaryngology literature. In this paper, we review a series of patients diagnosed with osteonecrosis, all treated with new generation bisphosphonates. Our objective is to inform and educate others, particularly otolaryngologists/head and neck surgeons, about this drug induced entity, a condition that should be recognized early to avoid potential devastating consequences.</div>
</front>
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