Osteopetrosis Complicated by Osteomyelitis of the Maxilla and Mandible: Light and Electron Microscopic Findings
Identifieur interne : 005749 ( Main/Merge ); précédent : 005748; suivant : 005750Osteopetrosis Complicated by Osteomyelitis of the Maxilla and Mandible: Light and Electron Microscopic Findings
Auteurs : Alexandre Elias Trivellato [Brésil] ; Michel Campos Ribeiro [Brésil] ; Cassio Edvard Sverzut [Brésil] ; Ermanno Bonucci [Italie] ; Antonio Nanci ; Paulo Tambasco De Oliveira [Brésil]Source :
- Head and Neck Pathology [ 1936-055X ] ; 2009.
Abstract
This report presents a case of osteopetrosis in a 25-year-old male, which was complicated by the development of osteomyelitis in the maxilla and mandible following traumatic injury and tooth extractions. The osteomyelitis in the mandible was refractory to marginal resection and antibiotic therapy. Partial resection with mandible reconstruction was then carried out. Light and backscattered electron scanning microscopy revealed sclerosis of spongy bone and variations in mineral density of the bone matrix. There was also a prominent periosteal bone formation in regions affected by osteomyelitis. An 18-month follow-up showed absence of active infections in the face and oral structures, with a focal area of bone exposure in the right parasymphysis. However, development of anemia and bone marrow deficiency will likely affect prognosis. The importance of preventive oral health care and dental/periodontal managements in osteopetrosis is emphasized.
Url:
DOI: 10.1007/s12105-009-0142-1
PubMed: 20596853
PubMed Central: 2811568
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uniqKey="Ribeiro M" first="Michel Campos" last="Ribeiro">Michel Campos Ribeiro</name><affiliation wicri:level="4"><nlm:aff id="Aff1">Department of Oral and Maxillofacial Surgery and Periodontology, School of Dentistry of Ribeirão Preto, University of São Paulo, Av. do Café, s/n-Campus USP, CEP 14040-904 Ribeirão Preto, SP Brazil</nlm:aff><orgName type="university">Université de São Paulo</orgName><country>Brésil</country><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName></affiliation></author><author><name sortKey="Sverzut, Cassio Edvard" sort="Sverzut, Cassio Edvard" uniqKey="Sverzut C" first="Cassio Edvard" last="Sverzut">Cassio Edvard Sverzut</name><affiliation wicri:level="4"><nlm:aff id="Aff1">Department of Oral and Maxillofacial Surgery and Periodontology, School of Dentistry of Ribeirão Preto, University of São Paulo, Av. do Café, s/n-Campus USP, CEP 14040-904 Ribeirão Preto, SP Brazil</nlm:aff><orgName 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The osteomyelitis in the mandible was refractory to marginal resection and antibiotic therapy. Partial resection with mandible reconstruction was then carried out. Light and backscattered electron scanning microscopy revealed sclerosis of spongy bone and variations in mineral density of the bone matrix. There was also a prominent periosteal bone formation in regions affected by osteomyelitis. An 18-month follow-up showed absence of active infections in the face and oral structures, with a focal area of bone exposure in the right parasymphysis. However, development of anemia and bone marrow deficiency will likely affect prognosis. The importance of preventive oral health care and dental/periodontal managements in osteopetrosis is emphasized.</p></div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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