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Electrodeposition of pronectin for titanium to augment gingival epithelium adhesion

Identifieur interne : 002C47 ( Main/Merge ); précédent : 002C46; suivant : 002C48

Electrodeposition of pronectin for titanium to augment gingival epithelium adhesion

Auteurs : Shingo Kawabata [Japon] ; Kazunari Asano [Japon] ; Atsuko Miyazawa [Japon] ; Tazuko Satoh [Japon] ; Yasuhiko Tabata [Japon]

Source :

RBID : ISTEX:1569586ED78BB37FD8A9361D93FD38691EFC342F

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English descriptors

Abstract

This paper is one trial of surface modification of titanium with pronectin F+ (PN) of an artificial protein to enhance gingival adhesion. Titanium plates were electrodeposited in the PN solution to prepare PN‐electrodeposited titanium plates. When PN detachment from the PN‐electrodeposited titanium plates was investigated, no detachment was observed, in contrast to the case of titanium plates simply coated with PN. A cell culture experiment demonstrated that electrodeposited PN had an inherent ability to enhance the initial attachment of gingival epithelial cells. The PN‐electrodeposited titanium plates were implanted between the gingival epithelium and the underlying bone tissue of rabbits to evaluate epithelial growth on the plates and their gingival adhesion. Non‐treated and PN‐coated titanium plates were used as controls. PN electrodeposition enhanced epithelial growth and adhesion of titanium plates to a significantly great extent compared with PN‐coated plates. These findings demonstrate that PN electrodeposition is a promising method to enhance epithelium adhesion onto a titanium surface. Copyright © 2012 John Wiley & Sons, Ltd.

Url:
DOI: 10.1002/term.527

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ISTEX:1569586ED78BB37FD8A9361D93FD38691EFC342F

Le document en format XML

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<div type="abstract">This paper is one trial of surface modification of titanium with pronectin F+ (PN) of an artificial protein to enhance gingival adhesion. Titanium plates were electrodeposited in the PN solution to prepare PN‐electrodeposited titanium plates. When PN detachment from the PN‐electrodeposited titanium plates was investigated, no detachment was observed, in contrast to the case of titanium plates simply coated with PN. A cell culture experiment demonstrated that electrodeposited PN had an inherent ability to enhance the initial attachment of gingival epithelial cells. The PN‐electrodeposited titanium plates were implanted between the gingival epithelium and the underlying bone tissue of rabbits to evaluate epithelial growth on the plates and their gingival adhesion. Non‐treated and PN‐coated titanium plates were used as controls. PN electrodeposition enhanced epithelial growth and adhesion of titanium plates to a significantly great extent compared with PN‐coated plates. These findings demonstrate that PN electrodeposition is a promising method to enhance epithelium adhesion onto a titanium surface. Copyright © 2012 John Wiley & Sons, Ltd.</div>
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