Early loading of hydrophilic titanium implants inserted in low-mineralized (D3 and D4) bone: one year results of a prospective clinical trial
Identifieur interne : 002552 ( Main/Merge ); précédent : 002551; suivant : 002553Early loading of hydrophilic titanium implants inserted in low-mineralized (D3 and D4) bone: one year results of a prospective clinical trial
Auteurs : Uwe Held [Suisse] ; Dennis Rohner [Suisse] ; Daniel Rothamel [Allemagne]Source :
- Head & Face Medicine [ 1746-160X ] ; 2013.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Bouche édentée (), Cicatrisation de plaie, Densité osseuse (physiologie), Facteurs temps, Femelle, Humains, Implants dentaires, Jeune adulte, Mordançage à l'acide, Mâle, Pose d'implant dentaire endo-osseux (), Propriétés de surface, Prothèse dentaire implanto-portée, Résultat thérapeutique, Sujet âgé, Titane (), Études de faisabilité, Études prospectives.
- MESH :
- physiologie : Densité osseuse.
- Adolescent, Adulte, Adulte d'âge moyen, Bouche édentée, Cicatrisation de plaie, Facteurs temps, Femelle, Humains, Implants dentaires, Jeune adulte, Mordançage à l'acide, Mâle, Pose d'implant dentaire endo-osseux, Propriétés de surface, Prothèse dentaire implanto-portée, Résultat thérapeutique, Sujet âgé, Titane, Études de faisabilité, Études prospectives.
English descriptors
- KwdEn :
- Acid Etching, Dental, Adolescent, Adult, Aged, Bone Density (physiology), Dental Implantation, Endosseous (methods), Dental Implants, Dental Prosthesis, Implant-Supported, Feasibility Studies, Female, Humans, Male, Middle Aged, Mouth, Edentulous (surgery), Prospective Studies, Surface Properties, Time Factors, Titanium (chemistry), Treatment Outcome, Wound Healing, Young Adult.
- MESH :
- chemical , chemistry : Titanium.
- chemical : Dental Implants.
- methods : Dental Implantation, Endosseous.
- physiology : Bone Density.
- surgery : Mouth, Edentulous.
- Acid Etching, Dental, Adolescent, Adult, Aged, Dental Prosthesis, Implant-Supported, Feasibility Studies, Female, Humans, Male, Middle Aged, Prospective Studies, Surface Properties, Time Factors, Treatment Outcome, Wound Healing, Young Adult.
Abstract
Pure titanium is the material of choice for contemporary dental implants. However, superficial reaction of the moderately rough titanium surface with atmospheric components decreases its hydrophilicity. INICELL® represents a chemical alteration and hydrophilization of a moderately rough i. e. sand-blasted and acid-etched titanium surface. The hydrophilicity leads to a more homogenous adsorption of proteins on the implant surface in-vitro, supporting the activation of a higher number of platelets and the generation of a homogenous, complete fibrin matrix in the early phases of osseointegration. This in turn helps to reduce the healing time and enhances the predictability of osseointegration in compromised bony situations.
The objective of this case series trial was therefore to investigate if early loading (after 8 weeks) of hydrophilic INICELL implants is feasible in patients with reduced bone quality.
In 10 patients, 35 hydrophilic implants were placed in sites revealing bone quality class 3 and 4, and uncovered after 4 weeks. Eight weeks later implants were released for loading if the tactile resistance was ≥35 Ncm. Lower resistances resulted in 12 weeks initial healing period. Insertion torque, ISQ, tactile resistance and vertical bone level were evaluated at implant installation, after 4 weeks (uncovering), 8 or 12 weeks (loading), and 12 weeks and one year after loading.
Mean implant insertion torque was 21 Ncm. 31 (88.6%) showed a tactile resistance of >35 Ncm after eight weeks and were released for prosthetic loading. Eight weeks after insertion, one implant (2.9%) had to be removed following a soft tissue complication. One implant had to be removed after 4 weeks due to a technical complication (fractured Osstell-abutment), it was therefore excluded from the analysis.
33 of 34 implants (97%) were loaded to occlusion and were in situ/functional one year after implantation. ISQs increased from 43 at baseline to 63 at eight weeks, and 72 at three months after loading. Then, ISQ remained constant until one year after loading.
Within the limitations of this prospective case series, hydrophilic implants may allow for shortening of the initial healing period even in bone with compromised density.
Url:
DOI: 10.1186/1746-160X-9-37
PubMed: 24321192
PubMed Central: 3866303
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PMC:3866303Le document en format XML
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<term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Bone Density (physiology)</term>
<term>Dental Implantation, Endosseous (methods)</term>
<term>Dental Implants</term>
<term>Dental Prosthesis, Implant-Supported</term>
<term>Feasibility Studies</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Mouth, Edentulous (surgery)</term>
<term>Prospective Studies</term>
<term>Surface Properties</term>
<term>Time Factors</term>
<term>Titanium (chemistry)</term>
<term>Treatment Outcome</term>
<term>Wound Healing</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Bouche édentée ()</term>
<term>Cicatrisation de plaie</term>
<term>Densité osseuse (physiologie)</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Humains</term>
<term>Implants dentaires</term>
<term>Jeune adulte</term>
<term>Mordançage à l'acide</term>
<term>Mâle</term>
<term>Pose d'implant dentaire endo-osseux ()</term>
<term>Propriétés de surface</term>
<term>Prothèse dentaire implanto-portée</term>
<term>Résultat thérapeutique</term>
<term>Sujet âgé</term>
<term>Titane ()</term>
<term>Études de faisabilité</term>
<term>Études prospectives</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Titanium</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Dental Implants</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Dental Implantation, Endosseous</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Densité osseuse</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Bone Density</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Mouth, Edentulous</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Acid Etching, Dental</term>
<term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Dental Prosthesis, Implant-Supported</term>
<term>Feasibility Studies</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Prospective Studies</term>
<term>Surface Properties</term>
<term>Time Factors</term>
<term>Treatment Outcome</term>
<term>Wound Healing</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Bouche édentée</term>
<term>Cicatrisation de plaie</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Humains</term>
<term>Implants dentaires</term>
<term>Jeune adulte</term>
<term>Mordançage à l'acide</term>
<term>Mâle</term>
<term>Pose d'implant dentaire endo-osseux</term>
<term>Propriétés de surface</term>
<term>Prothèse dentaire implanto-portée</term>
<term>Résultat thérapeutique</term>
<term>Sujet âgé</term>
<term>Titane</term>
<term>Études de faisabilité</term>
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<front><div type="abstract" xml:lang="en"><sec><title>Introduction</title>
<p>Pure titanium is the material of choice for contemporary dental implants. However, superficial reaction of the moderately rough titanium surface with atmospheric components decreases its hydrophilicity. INICELL® represents a chemical alteration and hydrophilization of a moderately rough i. e. sand-blasted and acid-etched titanium surface. The hydrophilicity leads to a more homogenous adsorption of proteins on the implant surface in-vitro, supporting the activation of a higher number of platelets and the generation of a homogenous, complete fibrin matrix in the early phases of osseointegration. This in turn helps to reduce the healing time and enhances the predictability of osseointegration in compromised bony situations.</p>
<p>The objective of this case series trial was therefore to investigate if early loading (after 8 weeks) of hydrophilic INICELL implants is feasible in patients with reduced bone quality.</p>
</sec>
<sec><title>Methods</title>
<p>In 10 patients, 35 hydrophilic implants were placed in sites revealing bone quality class 3 and 4, and uncovered after 4 weeks. Eight weeks later implants were released for loading if the tactile resistance was ≥35 Ncm. Lower resistances resulted in 12 weeks initial healing period. Insertion torque, ISQ, tactile resistance and vertical bone level were evaluated at implant installation, after 4 weeks (uncovering), 8 or 12 weeks (loading), and 12 weeks and one year after loading.</p>
</sec>
<sec><title>Results</title>
<p>Mean implant insertion torque was 21 Ncm. 31 (88.6%) showed a tactile resistance of >35 Ncm after eight weeks and were released for prosthetic loading. Eight weeks after insertion, one implant (2.9%) had to be removed following a soft tissue complication. One implant had to be removed after 4 weeks due to a technical complication (fractured Osstell-abutment), it was therefore excluded from the analysis.</p>
<p>33 of 34 implants (97%) were loaded to occlusion and were in situ/functional one year after implantation. ISQs increased from 43 at baseline to 63 at eight weeks, and 72 at three months after loading. Then, ISQ remained constant until one year after loading.</p>
</sec>
<sec><title>Conclusions</title>
<p>Within the limitations of this prospective case series, hydrophilic implants may allow for shortening of the initial healing period even in bone with compromised density.</p>
</sec>
</div>
</front>
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