Follow-Up of Implant Survival Comparing Ficoll and Bone Marrow Aspirate Concentrate Methods for Hard Tissue Regeneration with Mesenchymal Stem Cells in Humans
Identifieur interne : 001A71 ( Main/Merge ); précédent : 001A70; suivant : 001A72Follow-Up of Implant Survival Comparing Ficoll and Bone Marrow Aspirate Concentrate Methods for Hard Tissue Regeneration with Mesenchymal Stem Cells in Humans
Auteurs : Fabian Duttenhoefer ; Stefan F. Hieber ; Andres Stricker ; Rainer Schmelzeisen ; Ralf Gutwald ; Sebastian SauerbierSource :
- BioResearch Open Access [ 2164-7844 ] ; 2014.
Abstract
Url:
DOI: 10.1089/biores.2014.0003
PubMed: 24804168
PubMed Central: 3995205
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PMC:3995205Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Follow-Up of Implant Survival Comparing Ficoll and Bone Marrow Aspirate Concentrate Methods for Hard Tissue Regeneration with Mesenchymal Stem Cells in Humans</title>
<author><name sortKey="Duttenhoefer, Fabian" sort="Duttenhoefer, Fabian" uniqKey="Duttenhoefer F" first="Fabian" last="Duttenhoefer">Fabian Duttenhoefer</name>
</author>
<author><name sortKey="Hieber, Stefan F" sort="Hieber, Stefan F" uniqKey="Hieber S" first="Stefan F." last="Hieber">Stefan F. Hieber</name>
</author>
<author><name sortKey="Stricker, Andres" sort="Stricker, Andres" uniqKey="Stricker A" first="Andres" last="Stricker">Andres Stricker</name>
</author>
<author><name sortKey="Schmelzeisen, Rainer" sort="Schmelzeisen, Rainer" uniqKey="Schmelzeisen R" first="Rainer" last="Schmelzeisen">Rainer Schmelzeisen</name>
</author>
<author><name sortKey="Gutwald, Ralf" sort="Gutwald, Ralf" uniqKey="Gutwald R" first="Ralf" last="Gutwald">Ralf Gutwald</name>
</author>
<author><name sortKey="Sauerbier, Sebastian" sort="Sauerbier, Sebastian" uniqKey="Sauerbier S" first="Sebastian" last="Sauerbier">Sebastian Sauerbier</name>
</author>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Follow-Up of Implant Survival Comparing Ficoll and Bone Marrow Aspirate Concentrate Methods for Hard Tissue Regeneration with Mesenchymal Stem Cells in Humans</title>
<author><name sortKey="Duttenhoefer, Fabian" sort="Duttenhoefer, Fabian" uniqKey="Duttenhoefer F" first="Fabian" last="Duttenhoefer">Fabian Duttenhoefer</name>
</author>
<author><name sortKey="Hieber, Stefan F" sort="Hieber, Stefan F" uniqKey="Hieber S" first="Stefan F." last="Hieber">Stefan F. Hieber</name>
</author>
<author><name sortKey="Stricker, Andres" sort="Stricker, Andres" uniqKey="Stricker A" first="Andres" last="Stricker">Andres Stricker</name>
</author>
<author><name sortKey="Schmelzeisen, Rainer" sort="Schmelzeisen, Rainer" uniqKey="Schmelzeisen R" first="Rainer" last="Schmelzeisen">Rainer Schmelzeisen</name>
</author>
<author><name sortKey="Gutwald, Ralf" sort="Gutwald, Ralf" uniqKey="Gutwald R" first="Ralf" last="Gutwald">Ralf Gutwald</name>
</author>
<author><name sortKey="Sauerbier, Sebastian" sort="Sauerbier, Sebastian" uniqKey="Sauerbier S" first="Sebastian" last="Sauerbier">Sebastian Sauerbier</name>
</author>
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<series><title level="j">BioResearch Open Access</title>
<idno type="ISSN">2164-7844</idno>
<idno type="eISSN">2164-7860</idno>
<imprint><date when="2014">2014</date>
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<front><div type="abstract" xml:lang="en"><title>Abstract</title>
<p><bold><italic>Objective:</italic>
</bold>
Clinical follow-up of implant survival in 11 patients comparing two different methods for mesenchymal stem cell (MSC) isolation (Ficoll and bone marrow aspirate concentrate [BMAC]) applied in maxillary sinus augmentation.</p>
<p><bold><italic>Methods:</italic>
</bold>
Mononuclear cells, including MSCs, were concentrated with either Ficoll (control group, <italic>n</italic>
=6 sinus) or BMAC (test group, <italic>n</italic>
=12 sinus) and transplanted in combination with bovine bone mineral. A total of 50 implants were placed in a second surgical intervention (17 Ficoll/33 BMAC) and loaded after 4 months. Overall implant survival was assessed with a Kaplan-Meier model using package survival under R.</p>
<p><bold><italic>Results:</italic>
</bold>
Implant survival of the Ficoll group was 100% compared with the BMAC group, which had 93.4% survival (95% confidence interval, 0.849–1). The difference between the groups was not significant (<italic>p</italic>
=0.381).</p>
<p><bold><italic>Conclusion:</italic>
</bold>
The BMAC system is an effective and suitable “chair-side” method for clinical application in hard tissue regeneration.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Duttenhoefer, F" uniqKey="Duttenhoefer F">F Duttenhoefer</name>
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<biblStruct><analytic><author><name sortKey="Smiler, D" uniqKey="Smiler D">D Smiler</name>
</author>
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<biblStruct><analytic><author><name sortKey="Sauerbier, S" uniqKey="Sauerbier S">S Sauerbier</name>
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<biblStruct><analytic><author><name sortKey="Hermann, Pc" uniqKey="Hermann P">PC Hermann</name>
</author>
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<biblStruct><analytic><author><name sortKey="Wongchuensoontorn, C" uniqKey="Wongchuensoontorn C">C Wongchuensoontorn</name>
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<biblStruct><analytic><author><name sortKey="Buser, D" uniqKey="Buser D">D Buser</name>
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<biblStruct><analytic><author><name sortKey="Therneau, Tm" uniqKey="Therneau T">TM Therneau</name>
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<biblStruct><analytic><author><name sortKey="Rickert, D" uniqKey="Rickert D">D Rickert</name>
</author>
</analytic>
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</listBibl>
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