Induction of Prostaglandin Release from Macrophages by Bacterial Endotoxin
Identifieur interne : 009275 ( Main/Exploration ); précédent : 009274; suivant : 009276Induction of Prostaglandin Release from Macrophages by Bacterial Endotoxin
Auteurs : S. Offenbacher [Suisse, États-Unis] ; G. E. Salvi [Suisse]Source :
- Clinical Infectious Diseases [ 1058-4838 ] ; 1999-03.
Abstract
This review summarizes the role of the monocytic responses to lipopolysaccharide as it relates to periodontal disease severity. Data are presented which illustrate that the levels of prostaglandin E2 (PGE2) secreted by systemic peripheral blood monocytes in culture, in the presence of bacterial endotoxins, are highly correlated with the levels observed in the gingival crevicular fluid. Furthermore, the different periodontal diagnostic categories have varying levels of monocytic and crevicular fluid PGE2, in juxtaposition with clinical disease severity. These data are consistent with the concept that there is close synchrony between the systemic responsiveness of peripheral blood monocytes with regard to prostanoid synthesis and the local levels of mediator present within the gingival crevice.
Url:
DOI: 10.1086/515177
Affiliations:
- Suisse, États-Unis
- Canton de Berne
- Berne, Chapel Hill (Caroline du Nord)
- Université de Caroline du Nord à Chapel Hill
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000014
- to stream Istex, to step Curation: 000014
- to stream Istex, to step Checkpoint: 004141
- to stream Main, to step Merge: 009697
- to stream Main, to step Curation: 009275
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Induction of Prostaglandin Release from Macrophages by Bacterial Endotoxin</title>
<author><name sortKey="Offenbacher, S" sort="Offenbacher, S" uniqKey="Offenbacher S" first="S." last="Offenbacher">S. Offenbacher</name>
</author>
<author><name sortKey="Salvi, G E" sort="Salvi, G E" uniqKey="Salvi G" first="G. E." last="Salvi">G. E. Salvi</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:002DE9BE995900CBB769CA23378914E5E9EE592D</idno>
<date when="1999" year="1999">1999</date>
<idno type="doi">10.1086/515177</idno>
<idno type="url">https://api.istex.fr/document/002DE9BE995900CBB769CA23378914E5E9EE592D/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">000014</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000014</idno>
<idno type="wicri:Area/Istex/Curation">000014</idno>
<idno type="wicri:Area/Istex/Checkpoint">004141</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">004141</idno>
<idno type="wicri:doubleKey">1058-4838:1999:Offenbacher S:induction:of:prostaglandin</idno>
<idno type="wicri:Area/Main/Merge">009697</idno>
<idno type="wicri:Area/Main/Curation">009275</idno>
<idno type="wicri:Area/Main/Exploration">009275</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a">Induction of Prostaglandin Release from Macrophages by Bacterial Endotoxin</title>
<author><name sortKey="Offenbacher, S" sort="Offenbacher, S" uniqKey="Offenbacher S" first="S." last="Offenbacher">S. Offenbacher</name>
<affiliation wicri:level="4"><country xml:lang="fr">Suisse</country>
<wicri:regionArea>University of North Carolina at Chapel Hill, School of Dentistry, Department of Periodontology, Dental Research Center, Chapel Hill, North Carolina, USA, Berne</wicri:regionArea>
<placeName><settlement type="city">Berne</settlement>
<region type="région" nuts="3">Canton de Berne</region>
<settlement type="city">Chapel Hill (Caroline du Nord)</settlement>
</placeName>
<orgName type="university">Université de Caroline du Nord à Chapel Hill</orgName>
</affiliation>
<affiliation wicri:level="1"><country wicri:rule="url">États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Salvi, G E" sort="Salvi, G E" uniqKey="Salvi G" first="G. E." last="Salvi">G. E. Salvi</name>
<affiliation wicri:level="4"><country xml:lang="fr">Suisse</country>
<wicri:regionArea>University of North Carolina at Chapel Hill, School of Dentistry, Department of Periodontology, Dental Research Center, Chapel Hill, North Carolina, USA, Berne</wicri:regionArea>
<placeName><settlement type="city">Berne</settlement>
<region type="région" nuts="3">Canton de Berne</region>
<settlement type="city">Chapel Hill (Caroline du Nord)</settlement>
</placeName>
<orgName type="university">Université de Caroline du Nord à Chapel Hill</orgName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Clinical Infectious Diseases</title>
<title level="j" type="abbrev">Clinical Infectious Diseases</title>
<idno type="ISSN">1058-4838</idno>
<idno type="eISSN">1537-6591</idno>
<imprint><publisher>The University of Chicago Press</publisher>
<date type="published" when="1999-03">1999-03</date>
<biblScope unit="volume">28</biblScope>
<biblScope unit="issue">3</biblScope>
<biblScope unit="page" from="505">505</biblScope>
<biblScope unit="page" to="513">513</biblScope>
</imprint>
<idno type="ISSN">1058-4838</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">1058-4838</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract">This review summarizes the role of the monocytic responses to lipopolysaccharide as it relates to periodontal disease severity. Data are presented which illustrate that the levels of prostaglandin E2 (PGE2) secreted by systemic peripheral blood monocytes in culture, in the presence of bacterial endotoxins, are highly correlated with the levels observed in the gingival crevicular fluid. Furthermore, the different periodontal diagnostic categories have varying levels of monocytic and crevicular fluid PGE2, in juxtaposition with clinical disease severity. These data are consistent with the concept that there is close synchrony between the systemic responsiveness of peripheral blood monocytes with regard to prostanoid synthesis and the local levels of mediator present within the gingival crevice.</div>
</front>
</TEI>
<affiliations><list><country><li>Suisse</li>
<li>États-Unis</li>
</country>
<region><li>Canton de Berne</li>
</region>
<settlement><li>Berne</li>
<li>Chapel Hill (Caroline du Nord)</li>
</settlement>
<orgName><li>Université de Caroline du Nord à Chapel Hill</li>
</orgName>
</list>
<tree><country name="Suisse"><region name="Canton de Berne"><name sortKey="Offenbacher, S" sort="Offenbacher, S" uniqKey="Offenbacher S" first="S." last="Offenbacher">S. Offenbacher</name>
</region>
<name sortKey="Salvi, G E" sort="Salvi, G E" uniqKey="Salvi G" first="G. E." last="Salvi">G. E. Salvi</name>
</country>
<country name="États-Unis"><noRegion><name sortKey="Offenbacher, S" sort="Offenbacher, S" uniqKey="Offenbacher S" first="S." last="Offenbacher">S. Offenbacher</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 009275 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 009275 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= EdenteV2 |flux= Main |étape= Exploration |type= RBID |clé= ISTEX:002DE9BE995900CBB769CA23378914E5E9EE592D |texte= Induction of Prostaglandin Release from Macrophages by Bacterial Endotoxin }}
![]() | This area was generated with Dilib version V0.6.32. | ![]() |