Qualitative and quantitative studies of Gc (vitamin D‐binding protein) in normal subjects and patients with periodontal disease
Identifieur interne : 00C424 ( Main/Exploration ); précédent : 00C423; suivant : 00C425Qualitative and quantitative studies of Gc (vitamin D‐binding protein) in normal subjects and patients with periodontal disease
Auteurs : Joe W. Krayer [États-Unis] ; David L. Emerson [États-Unis] ; Pascal J. Goldschmidt-Clermont [États-Unis] ; Andre E. Nel [États-Unis] ; Philip A. Werner [États-Unis] ; Robert M. Galbraith [États-Unis]Source :
- Journal of Periodontal Research [ 0022-3484 ] ; 1987-07.
Descripteurs français
- Wicri :
- topic : Immunologie.
English descriptors
- KwdEn :
- American academy, Clinical immunology, Clinical periodontology, Clinical signs, Control subjects, Crevicular fiuid, Dentulous, Edentulous control subjects, Elisa, Elisa technique, Galbraith, Gingival, Gingival crevicular fiuid, Gingival index, Immunoglobulin, Immunology, Krayer, Medical university, Native sample, Normal controls, Normal subjects, Oral cavity, Parotid, Parotid saliva, Parotid saliva samples, Pathologic bone loss, Periodontal, Periodontal disease, Periodontal disease group, Periodontology, Petrini, Quantitative studies, Radiographic evidence, Riep, Rocket immunoelectrophoresis, Saliva, Saliva fiow, Saliva samples, Saturating amount, Saturating amounts, Tissue destruction, Vitamin protein, Whole saliva, Whole saliva samples, Yuodelis page.
- Teeft :
- American academy, Clinical immunology, Clinical periodontology, Clinical signs, Control subjects, Crevicular fiuid, Dentulous, Edentulous control subjects, Elisa, Elisa technique, Galbraith, Gingival, Gingival crevicular fiuid, Gingival index, Immunoglobulin, Immunology, Krayer, Medical university, Native sample, Normal controls, Normal subjects, Oral cavity, Parotid, Parotid saliva, Parotid saliva samples, Pathologic bone loss, Periodontal, Periodontal disease, Periodontal disease group, Periodontology, Petrini, Quantitative studies, Radiographic evidence, Riep, Rocket immunoelectrophoresis, Saliva, Saliva fiow, Saliva samples, Saturating amount, Saturating amounts, Tissue destruction, Vitamin protein, Whole saliva, Whole saliva samples, Yuodelis page.
Abstract
Qualitative and quantitative studies of Gc (Vitamin D‐binding protein) were carried out with whole and parotid saliva from 13 patients with periodontal disease, and 19 control subjects. Using an ELISA technique, a low concentration of Gc was found in the parotid saliva of all subjects. The whole saliva of patients with periodontal disease contained concentrations of Gc which were significantly increased over those in either dentulous or edentulous control subjects (p<0.01). In addition, the Gingival Index scores of these patients correlated with the concentration of Gc (r = 0.87; p<0.01). Rocket immunoelectrophoresis showed that > 90% of Gc in saliva from these patients was complexed with G‐actin.
Url:
DOI: 10.1111/j.1600-0765.1987.tb01583.x
Affiliations:
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Le document en format XML
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<series><title level="j" type="main">Journal of Periodontal Research</title>
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<term>Control subjects</term>
<term>Crevicular fiuid</term>
<term>Dentulous</term>
<term>Edentulous control subjects</term>
<term>Elisa</term>
<term>Elisa technique</term>
<term>Galbraith</term>
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<term>Gingival crevicular fiuid</term>
<term>Gingival index</term>
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<term>Normal controls</term>
<term>Normal subjects</term>
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<term>Parotid saliva</term>
<term>Parotid saliva samples</term>
<term>Pathologic bone loss</term>
<term>Periodontal</term>
<term>Periodontal disease</term>
<term>Periodontal disease group</term>
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<term>Rocket immunoelectrophoresis</term>
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<front><div type="abstract" xml:lang="en">Qualitative and quantitative studies of Gc (Vitamin D‐binding protein) were carried out with whole and parotid saliva from 13 patients with periodontal disease, and 19 control subjects. Using an ELISA technique, a low concentration of Gc was found in the parotid saliva of all subjects. The whole saliva of patients with periodontal disease contained concentrations of Gc which were significantly increased over those in either dentulous or edentulous control subjects (p<0.01). In addition, the Gingival Index scores of these patients correlated with the concentration of Gc (r = 0.87; p<0.01). Rocket immunoelectrophoresis showed that > 90% of Gc in saliva from these patients was complexed with G‐actin.</div>
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