Effects of dietary gluten elimination in patients with recurrent minor aphthous stomatitis and no detectable gluten enteropathy
Identifieur interne : 00AE30 ( Main/Exploration ); précédent : 00AE29; suivant : 00AE31Effects of dietary gluten elimination in patients with recurrent minor aphthous stomatitis and no detectable gluten enteropathy
Auteurs : I. P. Hunter [Royaume-Uni] ; M. M. Ferguson [Royaume-Uni, Nouvelle-Zélande] ; C. Scully [Royaume-Uni] ; A. R. Galloway [Royaume-Uni] ; A. N. H. Main [Royaume-Uni] ; R. I. Russell [Royaume-Uni]Source :
- Oral Surgery, Oral Medicine, Oral Pathology [ 0030-4220 ] ; 1993.
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Abstract
Abstract: Fifty patients with a history of minor recurrent aphthous stomatitis were entered into a 6-month double-blind controlled trial of a gluten-free diet. After hematologic and biochemical investigations and jejunal biopsy, one half of the group was given a gluten-free diet; the other half served as controls and received a gluten-free diet supplemented by gluten given blind (control diet). Twenty-three patients completed the trial, 11 patients on a gluten-free diet, 12 on the control diet. Four of the 11 on the gluten-free diet and 7 of the 12 on the control diet reported significant benefit in terms of minor recurrent aphthous stomatitis, but there was no statistical difference between the responses. The results fail to support studies that report widespread benefit in aphthae of gluten withdrawal and suggest simply a marked placebo response in the condition.
Url:
DOI: 10.1016/0030-4220(93)90232-S
Affiliations:
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Russell</name><affiliation wicri:level="2"><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>Gastroenterology Unit, Royal Infirmary, Glasgow</wicri:cityArea></affiliation></author></analytic><monogr></monogr><series><title level="j">Oral Surgery, Oral Medicine, Oral Pathology</title><title level="j" type="abbrev">OSOMOP</title><idno type="ISSN">0030-4220</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1993">1993</date><biblScope unit="volume">75</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="595">595</biblScope><biblScope unit="page" to="598">598</biblScope></imprint><idno type="ISSN">0030-4220</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0030-4220</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aphthous</term><term>Aphthous stomatitis</term><term>Control diet</term><term>Control group</term><term>Detectable gluten enteropathy</term><term>Enteropathy</term><term>Gluten</term><term>Gluten enteropathy</term><term>Gluten sensitivity</term><term>Gluten withdrawal</term><term>Jejunal</term><term>Miras</term><term>Oral medicine</term><term>Placebo</term><term>Significant difference</term><term>Stomatitis</term><term>Test group</term><term>University department</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Aphthous</term><term>Aphthous stomatitis</term><term>Control diet</term><term>Control group</term><term>Detectable gluten enteropathy</term><term>Enteropathy</term><term>Gluten</term><term>Gluten enteropathy</term><term>Gluten sensitivity</term><term>Gluten withdrawal</term><term>Jejunal</term><term>Miras</term><term>Oral medicine</term><term>Placebo</term><term>Significant difference</term><term>Stomatitis</term><term>Test group</term><term>University department</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Fifty patients with a history of minor recurrent aphthous stomatitis were entered into a 6-month double-blind controlled trial of a gluten-free diet. After hematologic and biochemical investigations and jejunal biopsy, one half of the group was given a gluten-free diet; the other half served as controls and received a gluten-free diet supplemented by gluten given blind (control diet). Twenty-three patients completed the trial, 11 patients on a gluten-free diet, 12 on the control diet. Four of the 11 on the gluten-free diet and 7 of the 12 on the control diet reported significant benefit in terms of minor recurrent aphthous stomatitis, but there was no statistical difference between the responses. The results fail to support studies that report widespread benefit in aphthae of gluten withdrawal and suggest simply a marked placebo response in the condition.</div></front></TEI><affiliations><list><country><li>Nouvelle-Zélande</li><li>Royaume-Uni</li></country><region><li>Écosse</li></region></list><tree><country name="Royaume-Uni"><region name="Écosse"><name sortKey="Hunter, I P" sort="Hunter, I P" uniqKey="Hunter I" first="I. 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