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A 15‐year follow‐up of phenytoin‐induced unilateral gingival hyperplasia: a case report

Identifieur interne : 00AC30 ( Main/Exploration ); précédent : 00AC29; suivant : 00AC31

A 15‐year follow‐up of phenytoin‐induced unilateral gingival hyperplasia: a case report

Auteurs : S. Tigaran [Danemark]

Source :

RBID : ISTEX:9166509E26DCACB7B0EA9CC5256EA47DD93EDE7B

English descriptors

Abstract

Introduction– The aim of this case report is to present a 15‐year follow‐up of a patient with phenytoin (PHT) intoxication with unilateral gingival hyperplasia (GH). Material and methods– A 50‐year‐old woman was followed‐up for 15 years clinically and paraclinically after a heavy PHT intoxication. Her immunoglobulins in serum were checked on PHT and after 15 years treatment with carbamazepine. Results– A gross mass of hyperplasia tissue found primarily in the left side of her mouth had disappeared and serum IgA which was subnormal at the first visit had normalized. Conclusion– It is possible to prevent GH from PHT treatment by intensive dental care, correct mouth hygiene and by change of treatment of carbamazepine.

Url:
DOI: 10.1111/j.1600-0404.1994.tb02739.x


Affiliations:


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Le document en format XML

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<term>Correct mouth hygiene</term>
<term>Cultured gingival fibroblasts</term>
<term>Epidermal</term>
<term>Epidermal growth factor receptor</term>
<term>Epilepsy</term>
<term>Fibroblast</term>
<term>Gingiva</term>
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<term>Gingival hyperplasia</term>
<term>Gingival overgrowth</term>
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<term>Hvidovre</term>
<term>Hvidovre hospital</term>
<term>Hyperplasia</term>
<term>Immunoglobulin</term>
<term>Langerhans cells</term>
<term>Neurol</term>
<term>Normal gingiva</term>
<term>Oral pathol</term>
<term>Phenytoin</term>
<term>Right side</term>
<term>Scand</term>
<term>Thin fibers</term>
<term>Tigaran</term>
<term>Unilateral gingival hyperplasia</term>
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<term>Phenytoin</term>
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<div type="abstract" xml:lang="en">Introduction– The aim of this case report is to present a 15‐year follow‐up of a patient with phenytoin (PHT) intoxication with unilateral gingival hyperplasia (GH). Material and methods– A 50‐year‐old woman was followed‐up for 15 years clinically and paraclinically after a heavy PHT intoxication. Her immunoglobulins in serum were checked on PHT and after 15 years treatment with carbamazepine. Results– A gross mass of hyperplasia tissue found primarily in the left side of her mouth had disappeared and serum IgA which was subnormal at the first visit had normalized. Conclusion– It is possible to prevent GH from PHT treatment by intensive dental care, correct mouth hygiene and by change of treatment of carbamazepine.</div>
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