Tacrolimus is not associated with gingival overgrowth in renal transplant patients
Identifieur interne : 008871 ( Main/Exploration ); précédent : 008870; suivant : 008872Tacrolimus is not associated with gingival overgrowth in renal transplant patients
Auteurs : Jacqueline A. James [Royaume-Uni] ; Sundos Jamal ; Peter S. Hull ; Tatiana V. Macfarlane ; Babatunde A. Campbell [Royaume-Uni] ; Robert W. G. Johnson [Royaume-Uni] ; Colin D. Short [Royaume-Uni]Source :
- Journal of Clinical Periodontology [ 0303-6979 ] ; 2001-09.
English descriptors
- KwdEn :
- Adverse effects, Allograft, Alternative immunosuppressant, Calcium antagonists, Cette etude, Clinical periodontology, Control group, Control individuals, Cyclosporin, Cyclosporin gingival overgrowth, Gingival, Gingival enlargement, Gingival health, Gingival hyperplasia, Gingival overgrowth, Gingival tissues, Immunosuppressed, Overgrowth, Overgrowth scores, Papilla, Periodontology, Plaque, Present study, Renal, Renal transplant patients, Renal transplant recipients, Rtps, Seymour, Tacrolimus, Tacrolimus group, Transplant, Transplant patients, Transplantation.
- Teeft :
- Adverse effects, Allograft, Alternative immunosuppressant, Calcium antagonists, Cette etude, Clinical periodontology, Control group, Control individuals, Cyclosporin, Cyclosporin gingival overgrowth, Gingival, Gingival enlargement, Gingival health, Gingival hyperplasia, Gingival overgrowth, Gingival tissues, Immunosuppressed, Overgrowth, Overgrowth scores, Papilla, Periodontology, Plaque, Present study, Renal, Renal transplant patients, Renal transplant recipients, Rtps, Seymour, Tacrolimus, Tacrolimus group, Transplant, Transplant patients, Transplantation.
Abstract
Background: Cyclosporin A is used extensively to prevent the rejection of allogenic renal transplants. However, it is associated with a variety of undesirable side effects including gingival overgrowth. Tacrolimus (FK506), has been marketed as an effective alternative immunosuppressant to cyclosporin A and recent subjective reports suggest patients taking it complain infrequently of gingival problems. This clinical investigation was undertaken to confirm whether or not tacrolimus adversely affected the gingival health of renal transplant recipients.
Url:
DOI: 10.1034/j.1600-051x.2001.028009848.x
Affiliations:
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James</name><affiliation></affiliation><affiliation wicri:level="1"><country wicri:rule="url">Royaume-Uni</country></affiliation></author><author><name sortKey="Jamal, Sundos" sort="Jamal, Sundos" uniqKey="Jamal S" first="Sundos" last="Jamal">Sundos Jamal</name><affiliation><wicri:noCountry code="subField">6FH;</wicri:noCountry></affiliation></author><author><name sortKey="Hull, Peter S" sort="Hull, Peter S" uniqKey="Hull P" first="Peter S." last="Hull">Peter S. Hull</name><affiliation><wicri:noCountry code="subField">6FH;</wicri:noCountry></affiliation></author><author><name sortKey="Macfarlane, Tatiana V" sort="Macfarlane, Tatiana V" uniqKey="Macfarlane T" first="Tatiana V." last="Macfarlane">Tatiana V. Macfarlane</name><affiliation><wicri:noCountry code="subField">6FH;</wicri:noCountry></affiliation></author><author><name sortKey="Campbell, Babatunde A" sort="Campbell, Babatunde A" uniqKey="Campbell B" first="Babatunde A." last="Campbell">Babatunde A. 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Short</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Renal Transplant Unit, Central Manchester Healthcare Trust, Oxford Road, Manchester, M13 9WL</wicri:regionArea><wicri:noRegion>M13 9WL</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Journal of Clinical Periodontology</title><title level="j" type="alt">JOURNAL OF CLINICAL PERIODONTOLOGY</title><idno type="ISSN">0303-6979</idno><idno type="eISSN">1600-051X</idno><imprint><biblScope unit="vol">28</biblScope><biblScope unit="issue">9</biblScope><biblScope unit="page" from="848">848</biblScope><biblScope unit="page" to="852">852</biblScope><biblScope unit="page-count">5</biblScope><publisher>Munksgaard International Publishers</publisher><pubPlace>Copenhagen</pubPlace><date type="published" when="2001-09">2001-09</date></imprint><idno type="ISSN">0303-6979</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0303-6979</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adverse effects</term><term>Allograft</term><term>Alternative immunosuppressant</term><term>Calcium antagonists</term><term>Cette etude</term><term>Clinical periodontology</term><term>Control group</term><term>Control individuals</term><term>Cyclosporin</term><term>Cyclosporin gingival overgrowth</term><term>Gingival</term><term>Gingival enlargement</term><term>Gingival health</term><term>Gingival hyperplasia</term><term>Gingival overgrowth</term><term>Gingival tissues</term><term>Immunosuppressed</term><term>Overgrowth</term><term>Overgrowth scores</term><term>Papilla</term><term>Periodontology</term><term>Plaque</term><term>Present study</term><term>Renal</term><term>Renal transplant patients</term><term>Renal transplant recipients</term><term>Rtps</term><term>Seymour</term><term>Tacrolimus</term><term>Tacrolimus group</term><term>Transplant</term><term>Transplant patients</term><term>Transplantation</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Adverse effects</term><term>Allograft</term><term>Alternative immunosuppressant</term><term>Calcium antagonists</term><term>Cette etude</term><term>Clinical periodontology</term><term>Control group</term><term>Control individuals</term><term>Cyclosporin</term><term>Cyclosporin gingival overgrowth</term><term>Gingival</term><term>Gingival enlargement</term><term>Gingival health</term><term>Gingival hyperplasia</term><term>Gingival overgrowth</term><term>Gingival tissues</term><term>Immunosuppressed</term><term>Overgrowth</term><term>Overgrowth scores</term><term>Papilla</term><term>Periodontology</term><term>Plaque</term><term>Present study</term><term>Renal</term><term>Renal transplant patients</term><term>Renal transplant recipients</term><term>Rtps</term><term>Seymour</term><term>Tacrolimus</term><term>Tacrolimus group</term><term>Transplant</term><term>Transplant patients</term><term>Transplantation</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract">Background: Cyclosporin A is used extensively to prevent the rejection of allogenic renal transplants. However, it is associated with a variety of undesirable side effects including gingival overgrowth. Tacrolimus (FK506), has been marketed as an effective alternative immunosuppressant to cyclosporin A and recent subjective reports suggest patients taking it complain infrequently of gingival problems. This clinical investigation was undertaken to confirm whether or not tacrolimus adversely affected the gingival health of renal transplant recipients.</div></front></TEI><affiliations><list><country><li>Royaume-Uni</li></country></list><tree><noCountry><name sortKey="Hull, Peter S" sort="Hull, Peter S" uniqKey="Hull P" first="Peter S." last="Hull">Peter S. Hull</name><name sortKey="Jamal, Sundos" sort="Jamal, Sundos" uniqKey="Jamal S" first="Sundos" last="Jamal">Sundos Jamal</name><name sortKey="Macfarlane, Tatiana V" sort="Macfarlane, Tatiana V" uniqKey="Macfarlane T" first="Tatiana V." last="Macfarlane">Tatiana V. Macfarlane</name></noCountry><country name="Royaume-Uni"><noRegion><name sortKey="James, Jacqueline A" sort="James, Jacqueline A" uniqKey="James J" first="Jacqueline A." last="James">Jacqueline A. James</name></noRegion><name sortKey="Campbell, Babatunde A" sort="Campbell, Babatunde A" uniqKey="Campbell B" first="Babatunde A." last="Campbell">Babatunde A. Campbell</name><name sortKey="Johnson, Robert W G" sort="Johnson, Robert W G" uniqKey="Johnson R" first="Robert W. G." last="Johnson">Robert W. G. Johnson</name><name sortKey="Short, Colin D" sort="Short, Colin D" uniqKey="Short C" first="Colin D." last="Short">Colin D. Short</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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