Clinical and histologic evaluation of a mineralized block allograft: results from the developmental period (2001-2004).
Identifieur interne : 006D22 ( Main/Exploration ); précédent : 006D21; suivant : 006D23Clinical and histologic evaluation of a mineralized block allograft: results from the developmental period (2001-2004).
Auteurs : J Daulton Keith ; Paul Petrungaro ; Joseph A. Leonetti ; Charles W. Elwell ; Karl J. Zeren ; Chris Caputo ; Nikolaos G. Nikitakis ; Christoph Schöpf ; Michael M. WarnerSource :
- The International journal of periodontics & restorative dentistry [ 0198-7569 ] ; 2006.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Analyse de survie, Cicatrisation de plaie (physiologie), Femelle, Humains, Implants dentaires, Lâchage de suture (), Mâchoire partiellement édentée (), Mâle, Pose d'implant dentaire endo-osseux (), Prothèse dentaire implanto-portée, Reconstruction de crête alvéolaire (), Reconstruction de crête alvéolaire (instrumentation), Régénération tissulaire guidée parodontale, Sujet âgé, Survie du greffon, Transplantation homologue, Transplantation osseuse (), Transplantation osseuse (anatomopathologie), Vis orthopédiques, Études de suivi, Études prospectives.
- MESH :
- anatomopathologie : Transplantation osseuse.
- physiologie : Cicatrisation de plaie.
- Adolescent, Adulte, Adulte d'âge moyen, Analyse de survie, Femelle, Humains, Implants dentaires, Lâchage de suture, Mâchoire partiellement édentée, Mâle, Pose d'implant dentaire endo-osseux, Prothèse dentaire implanto-portée, Reconstruction de crête alvéolaire, Régénération tissulaire guidée parodontale, Sujet âgé, Survie du greffon, Transplantation homologue, Transplantation osseuse, Vis orthopédiques, Études de suivi, Études prospectives.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Alveolar Ridge Augmentation (instrumentation), Alveolar Ridge Augmentation (methods), Bone Screws, Bone Transplantation (methods), Bone Transplantation (pathology), Dental Implantation, Endosseous (methods), Dental Implants, Dental Prosthesis, Implant-Supported, Female, Follow-Up Studies, Graft Survival, Guided Tissue Regeneration, Periodontal, Humans, Jaw, Edentulous, Partially (surgery), Male, Middle Aged, Prospective Studies, Surgical Wound Dehiscence (therapy), Survival Analysis, Transplantation, Homologous, Wound Healing (physiology).
- MESH :
- chemical : Dental Implants.
- instrumentation : Alveolar Ridge Augmentation.
- methods : Alveolar Ridge Augmentation, Bone Transplantation, Dental Implantation, Endosseous.
- pathology : Bone Transplantation.
- physiology : Wound Healing.
- surgery : Jaw, Edentulous, Partially.
- therapy : Surgical Wound Dehiscence.
- Adolescent, Adult, Aged, Bone Screws, Dental Prosthesis, Implant-Supported, Female, Follow-Up Studies, Graft Survival, Guided Tissue Regeneration, Periodontal, Humans, Male, Middle Aged, Prospective Studies, Survival Analysis, Transplantation, Homologous.
Abstract
This article reports on a multicenter evaluation of a novel, sterile, antigen-inactivated, mineralized block allograft in humans during a 3-year developmental period. Consecutive partially edentulous patients (n = 73) with severe localized ridge defects (n = 82) were treated with the material. After 4 to 6 months of healing, tapered screw implants were placed in the grafted bone and subsequently restored. Patients were monitored 25 to 36 months after prosthetic restoration. A biopsy was taken of one patient and submitted for histomorphometric analysis. Block allograft survival was 93% at 12 months, and resorption ranged from none (69%) to slight (0 to 2 mm) (31%) for all surviving allografts. Seven block allografts failed and were removed because of improper contouring, prosthesis impingement, and/or infection. The sites were successfully re-treated and restored with dental implants. Soft tissue dehiscence was successfully treated in seven other sites. Implant survival was 99%. One implant failed without allograft failure. It was replaced with a larger-diameter implant, treated with guided bone regeneration, and subsequently restored. Histomorphometric analysis showed rapid incorporation of the allograft at 6 months without inflammation or necrosis. The block allografts were more technique-sensitive than autografts, which necessitated meticulous surgical technique and follow-up. Short-term results for the block allografts indicated a high degree of predictability, but long-term follow-up is needed.
PubMed: 16939013
Affiliations:
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Le document en format XML
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Leonetti</name></author><author><name sortKey="Elwell, Charles W" sort="Elwell, Charles W" uniqKey="Elwell C" first="Charles W" last="Elwell">Charles W. Elwell</name></author><author><name sortKey="Zeren, Karl J" sort="Zeren, Karl J" uniqKey="Zeren K" first="Karl J" last="Zeren">Karl J. Zeren</name></author><author><name sortKey="Caputo, Chris" sort="Caputo, Chris" uniqKey="Caputo C" first="Chris" last="Caputo">Chris Caputo</name></author><author><name sortKey="Nikitakis, Nikolaos G" sort="Nikitakis, Nikolaos G" uniqKey="Nikitakis N" first="Nikolaos G" last="Nikitakis">Nikolaos G. Nikitakis</name></author><author><name sortKey="Schopf, Christoph" sort="Schopf, Christoph" uniqKey="Schopf C" first="Christoph" last="Schöpf">Christoph Schöpf</name></author><author><name sortKey="Warner, Michael M" sort="Warner, Michael M" uniqKey="Warner M" first="Michael M" last="Warner">Michael M. Warner</name></author></analytic><series><title level="j">The International journal of periodontics & restorative dentistry</title><idno type="ISSN">0198-7569</idno><imprint><date when="2006" type="published">2006</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Alveolar Ridge Augmentation (instrumentation)</term><term>Alveolar Ridge Augmentation (methods)</term><term>Bone Screws</term><term>Bone Transplantation (methods)</term><term>Bone Transplantation (pathology)</term><term>Dental Implantation, Endosseous (methods)</term><term>Dental Implants</term><term>Dental Prosthesis, Implant-Supported</term><term>Female</term><term>Follow-Up Studies</term><term>Graft Survival</term><term>Guided Tissue Regeneration, Periodontal</term><term>Humans</term><term>Jaw, Edentulous, Partially (surgery)</term><term>Male</term><term>Middle Aged</term><term>Prospective Studies</term><term>Surgical Wound Dehiscence (therapy)</term><term>Survival Analysis</term><term>Transplantation, Homologous</term><term>Wound Healing (physiology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Analyse de survie</term><term>Cicatrisation de plaie (physiologie)</term><term>Femelle</term><term>Humains</term><term>Implants dentaires</term><term>Lâchage de suture ()</term><term>Mâchoire partiellement édentée ()</term><term>Mâle</term><term>Pose d'implant dentaire endo-osseux ()</term><term>Prothèse dentaire implanto-portée</term><term>Reconstruction de crête alvéolaire ()</term><term>Reconstruction de crête alvéolaire (instrumentation)</term><term>Régénération tissulaire guidée parodontale</term><term>Sujet âgé</term><term>Survie du greffon</term><term>Transplantation homologue</term><term>Transplantation osseuse ()</term><term>Transplantation osseuse (anatomopathologie)</term><term>Vis orthopédiques</term><term>Études de suivi</term><term>Études prospectives</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Dental Implants</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Transplantation osseuse</term></keywords><keywords scheme="MESH" qualifier="instrumentation" xml:lang="en"><term>Alveolar Ridge Augmentation</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Alveolar Ridge Augmentation</term><term>Bone Transplantation</term><term>Dental Implantation, Endosseous</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Bone Transplantation</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Cicatrisation de plaie</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Wound Healing</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Jaw, Edentulous, Partially</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Surgical Wound Dehiscence</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Bone Screws</term><term>Dental Prosthesis, Implant-Supported</term><term>Female</term><term>Follow-Up Studies</term><term>Graft Survival</term><term>Guided Tissue Regeneration, Periodontal</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Prospective Studies</term><term>Survival Analysis</term><term>Transplantation, Homologous</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Analyse de survie</term><term>Femelle</term><term>Humains</term><term>Implants dentaires</term><term>Lâchage de suture</term><term>Mâchoire partiellement édentée</term><term>Mâle</term><term>Pose d'implant dentaire endo-osseux</term><term>Prothèse dentaire implanto-portée</term><term>Reconstruction de crête alvéolaire</term><term>Régénération tissulaire guidée parodontale</term><term>Sujet âgé</term><term>Survie du greffon</term><term>Transplantation homologue</term><term>Transplantation osseuse</term><term>Vis orthopédiques</term><term>Études de suivi</term><term>Études prospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">This article reports on a multicenter evaluation of a novel, sterile, antigen-inactivated, mineralized block allograft in humans during a 3-year developmental period. Consecutive partially edentulous patients (n = 73) with severe localized ridge defects (n = 82) were treated with the material. After 4 to 6 months of healing, tapered screw implants were placed in the grafted bone and subsequently restored. Patients were monitored 25 to 36 months after prosthetic restoration. A biopsy was taken of one patient and submitted for histomorphometric analysis. Block allograft survival was 93% at 12 months, and resorption ranged from none (69%) to slight (0 to 2 mm) (31%) for all surviving allografts. Seven block allografts failed and were removed because of improper contouring, prosthesis impingement, and/or infection. The sites were successfully re-treated and restored with dental implants. Soft tissue dehiscence was successfully treated in seven other sites. Implant survival was 99%. One implant failed without allograft failure. It was replaced with a larger-diameter implant, treated with guided bone regeneration, and subsequently restored. Histomorphometric analysis showed rapid incorporation of the allograft at 6 months without inflammation or necrosis. The block allografts were more technique-sensitive than autografts, which necessitated meticulous surgical technique and follow-up. Short-term results for the block allografts indicated a high degree of predictability, but long-term follow-up is needed.</div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Caputo, Chris" sort="Caputo, Chris" uniqKey="Caputo C" first="Chris" last="Caputo">Chris Caputo</name><name sortKey="Elwell, Charles W" sort="Elwell, Charles W" uniqKey="Elwell C" first="Charles W" last="Elwell">Charles W. Elwell</name><name sortKey="Keith, J Daulton" sort="Keith, J Daulton" uniqKey="Keith J" first="J Daulton" last="Keith">J Daulton Keith</name><name sortKey="Leonetti, Joseph A" sort="Leonetti, Joseph A" uniqKey="Leonetti J" first="Joseph A" last="Leonetti">Joseph A. Leonetti</name><name sortKey="Nikitakis, Nikolaos G" sort="Nikitakis, Nikolaos G" uniqKey="Nikitakis N" first="Nikolaos G" last="Nikitakis">Nikolaos G. Nikitakis</name><name sortKey="Petrungaro, Paul" sort="Petrungaro, Paul" uniqKey="Petrungaro P" first="Paul" last="Petrungaro">Paul Petrungaro</name><name sortKey="Schopf, Christoph" sort="Schopf, Christoph" uniqKey="Schopf C" first="Christoph" last="Schöpf">Christoph Schöpf</name><name sortKey="Warner, Michael M" sort="Warner, Michael M" uniqKey="Warner M" first="Michael M" last="Warner">Michael M. Warner</name><name sortKey="Zeren, Karl J" sort="Zeren, Karl J" uniqKey="Zeren K" first="Karl J" last="Zeren">Karl J. Zeren</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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