Effect of phosphate group addition on the properties of denture base resins
Identifieur interne : 006023 ( Main/Exploration ); précédent : 006022; suivant : 006024Effect of phosphate group addition on the properties of denture base resins
Auteurs : Gaurav Puri ; David W. Berzins ; Virendra B. Dhuru ; Periathamby A. Raj ; Sameer K. Rambhia ; Gunjan Dhir ; Andrew R. DentinoSource :
- The Journal of prosthetic dentistry [ 0022-3913 ] ; 2008.
Abstract
Acrylic resins are prone to microbial adherence, especially by
The purpose of this study was to investigate the physical and mechanical properties of phosphate-containing polymethyl methacrylate resins for their suitability as a denture material.
Using PMMA with cross-linker (Lucitone 199) as a control, 4 experimental groups containing various levels of phosphate with and without cross-linker were generated. The properties examined were impact strength, fracture toughness, wettability (contact angle), and resin bonding ability to denture teeth. Impact strength was tested in the Izod configuration (n=16), and fracture toughness (n=13) was measured using the single-edge notched bend test. Wettability was determined by calculating the contact angle of water on the material surface (n=12), while ISO 1567 was used for bonding ability (n=12). The data were analyzed by 1- and 2-way ANOVA (α=.05).
A trend of increased hydrophilicity, as indicated by lower contact angle, was observed with increased concentrations of phosphate. With regard to the other properties, no significant differences were found when compared with the control acrylic resin.
No adverse physical effect due to the addition of a phosphate-containing monomer was found in the acrylic denture resins. Additional mechanical and physical properties, biocompatibility, and clinical efficacy studies are needed to confirm the in vivo anti-
Url:
DOI: 10.1016/S0022-3913(08)60210-3
PubMed: 18922259
PubMed Central: 2659143
Affiliations:
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Dhuru</name><affiliation><nlm:aff id="A3">Adjunct Associate Professor (Clinical) of Biomaterials, Department of General Dental Sciences, Marquette University School of Dentistry, Milwaukee, Wis.</nlm:aff><wicri:noCountry code="subfield">Wis.</wicri:noCountry></affiliation></author><author><name sortKey="Raj, Periathamby A" sort="Raj, Periathamby A" uniqKey="Raj P" first="Periathamby A." last="Raj">Periathamby A. Raj</name><affiliation><nlm:aff id="A4">Chief Science Officer, PeriDent Therapeutics, North Andover, Mass.</nlm:aff><wicri:noCountry code="subfield">Mass.</wicri:noCountry></affiliation></author><author><name sortKey="Rambhia, Sameer K" sort="Rambhia, Sameer K" uniqKey="Rambhia S" first="Sameer K." last="Rambhia">Sameer K. Rambhia</name><affiliation><nlm:aff id="A5">Assistant Professor, Department of General Dental Sciences, Marquette University School of Dentistry, Milwaukee, Wis.</nlm:aff><wicri:noCountry code="subfield">Wis.</wicri:noCountry></affiliation></author><author><name sortKey="Dhir, Gunjan" sort="Dhir, Gunjan" uniqKey="Dhir G" first="Gunjan" last="Dhir">Gunjan Dhir</name><affiliation><nlm:aff id="A6">Private practice, Spokane, Wash.</nlm:aff><wicri:noCountry code="subfield">Wash.</wicri:noCountry></affiliation></author><author><name sortKey="Dentino, Andrew R" sort="Dentino, Andrew R" uniqKey="Dentino A" first="Andrew R." last="Dentino">Andrew R. Dentino</name><affiliation><nlm:aff id="A7">Associate Professor and Program Director of Periodontics, Department of Surgical Sciences, Marquette University School of Dentistry, Milwaukee, Wis.</nlm:aff><wicri:noCountry code="subfield">Wis.</wicri:noCountry></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">18922259</idno><idno type="pmc">2659143</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659143</idno><idno type="RBID">PMC:2659143</idno><idno type="doi">10.1016/S0022-3913(08)60210-3</idno><date when="2008">2008</date><idno type="wicri:Area/Pmc/Corpus">002084</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002084</idno><idno type="wicri:Area/Pmc/Curation">002084</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002084</idno><idno type="wicri:Area/Pmc/Checkpoint">002638</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002638</idno><idno type="wicri:Area/Ncbi/Merge">002429</idno><idno type="wicri:Area/Ncbi/Curation">002429</idno><idno type="wicri:Area/Ncbi/Checkpoint">002429</idno><idno type="wicri:doubleKey">0022-3913:2008:Puri G:effect:of:phosphate</idno><idno type="wicri:Area/Main/Merge">006099</idno><idno type="wicri:Area/Main/Curation">006023</idno><idno type="wicri:Area/Main/Exploration">006023</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Effect of phosphate group addition on the properties of denture base resins</title><author><name sortKey="Puri, Gaurav" sort="Puri, Gaurav" uniqKey="Puri G" first="Gaurav" last="Puri">Gaurav Puri</name><affiliation><nlm:aff id="A1">Private practice, Spokane, Wash.</nlm:aff><wicri:noCountry code="subfield">Wash.</wicri:noCountry></affiliation></author><author><name sortKey="Berzins, David W" sort="Berzins, David W" uniqKey="Berzins D" first="David W." last="Berzins">David W. Berzins</name><affiliation><nlm:aff id="A2">Assistant Professor and Graduate Program Director for Dental Biomaterials, Department of General Dental Sciences, Marquette University School of Dentistry, Milwaukee, Wis.</nlm:aff><wicri:noCountry code="subfield">Wis.</wicri:noCountry></affiliation></author><author><name sortKey="Dhuru, Virendra B" sort="Dhuru, Virendra B" uniqKey="Dhuru V" first="Virendra B." last="Dhuru">Virendra B. Dhuru</name><affiliation><nlm:aff id="A3">Adjunct Associate Professor (Clinical) of Biomaterials, Department of General Dental Sciences, Marquette University School of Dentistry, Milwaukee, Wis.</nlm:aff><wicri:noCountry code="subfield">Wis.</wicri:noCountry></affiliation></author><author><name sortKey="Raj, Periathamby A" sort="Raj, Periathamby A" uniqKey="Raj P" first="Periathamby A." last="Raj">Periathamby A. Raj</name><affiliation><nlm:aff id="A4">Chief Science Officer, PeriDent Therapeutics, North Andover, Mass.</nlm:aff><wicri:noCountry code="subfield">Mass.</wicri:noCountry></affiliation></author><author><name sortKey="Rambhia, Sameer K" sort="Rambhia, Sameer K" uniqKey="Rambhia S" first="Sameer K." last="Rambhia">Sameer K. Rambhia</name><affiliation><nlm:aff id="A5">Assistant Professor, Department of General Dental Sciences, Marquette University School of Dentistry, Milwaukee, Wis.</nlm:aff><wicri:noCountry code="subfield">Wis.</wicri:noCountry></affiliation></author><author><name sortKey="Dhir, Gunjan" sort="Dhir, Gunjan" uniqKey="Dhir G" first="Gunjan" last="Dhir">Gunjan Dhir</name><affiliation><nlm:aff id="A6">Private practice, Spokane, Wash.</nlm:aff><wicri:noCountry code="subfield">Wash.</wicri:noCountry></affiliation></author><author><name sortKey="Dentino, Andrew R" sort="Dentino, Andrew R" uniqKey="Dentino A" first="Andrew R." last="Dentino">Andrew R. Dentino</name><affiliation><nlm:aff id="A7">Associate Professor and Program Director of Periodontics, Department of Surgical Sciences, Marquette University School of Dentistry, Milwaukee, Wis.</nlm:aff><wicri:noCountry code="subfield">Wis.</wicri:noCountry></affiliation></author></analytic><series><title level="j">The Journal of prosthetic dentistry</title><idno type="ISSN">0022-3913</idno><idno type="eISSN">1097-6841</idno><imprint><date when="2008">2008</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="S1"><title>Statement of problem</title><p id="P1">Acrylic resins are prone to microbial adherence, especially by <italic>Candida albicans</italic>. Surface-charged resins alter the ionic interaction between the denture resin and <italic>Candida</italic> hyphae, and these resins are being developed as a means to reduce microbial colonization on the denture surface.</p></sec><sec id="S2"><title>Purpose</title><p id="P2">The purpose of this study was to investigate the physical and mechanical properties of phosphate-containing polymethyl methacrylate resins for their suitability as a denture material.</p></sec><sec sec-type="materials|methods" id="S3"><title>Material and methods</title><p id="P3">Using PMMA with cross-linker (Lucitone 199) as a control, 4 experimental groups containing various levels of phosphate with and without cross-linker were generated. The properties examined were impact strength, fracture toughness, wettability (contact angle), and resin bonding ability to denture teeth. Impact strength was tested in the Izod configuration (n=16), and fracture toughness (n=13) was measured using the single-edge notched bend test. Wettability was determined by calculating the contact angle of water on the material surface (n=12), while ISO 1567 was used for bonding ability (n=12). The data were analyzed by 1- and 2-way ANOVA (α=.05).</p></sec><sec id="S4"><title>Results</title><p id="P4">A trend of increased hydrophilicity, as indicated by lower contact angle, was observed with increased concentrations of phosphate. With regard to the other properties, no significant differences were found when compared with the control acrylic resin.</p></sec><sec id="S5"><title>Conclusions</title><p id="P5">No adverse physical effect due to the addition of a phosphate-containing monomer was found in the acrylic denture resins. Additional mechanical and physical properties, biocompatibility, and clinical efficacy studies are needed to confirm the in vivo anti-<italic>Candida</italic> activity of these novel resins.</p></sec></div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Berzins, David W" sort="Berzins, David W" uniqKey="Berzins D" first="David W." last="Berzins">David W. Berzins</name><name sortKey="Dentino, Andrew R" sort="Dentino, Andrew R" uniqKey="Dentino A" first="Andrew R." last="Dentino">Andrew R. Dentino</name><name sortKey="Dhir, Gunjan" sort="Dhir, Gunjan" uniqKey="Dhir G" first="Gunjan" last="Dhir">Gunjan Dhir</name><name sortKey="Dhuru, Virendra B" sort="Dhuru, Virendra B" uniqKey="Dhuru V" first="Virendra B." last="Dhuru">Virendra B. Dhuru</name><name sortKey="Puri, Gaurav" sort="Puri, Gaurav" uniqKey="Puri G" first="Gaurav" last="Puri">Gaurav Puri</name><name sortKey="Raj, Periathamby A" sort="Raj, Periathamby A" uniqKey="Raj P" first="Periathamby A." last="Raj">Periathamby A. Raj</name><name sortKey="Rambhia, Sameer K" sort="Rambhia, Sameer K" uniqKey="Rambhia S" first="Sameer K." last="Rambhia">Sameer K. Rambhia</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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