Phenytoin‐induced gingival overgrowth
Identifieur interne : 003865 ( Main/Exploration ); précédent : 003864; suivant : 003866Phenytoin‐induced gingival overgrowth
Auteurs : R. Arya [Inde] ; S. Gulati [Inde]Source :
- Acta Neurologica Scandinavica [ 0001-6314 ] ; 2012-03.
English descriptors
- KwdEn :
- Anatomic crowns, Anterior teeth, Broblasts, Clin periodontol, Epileptic children, Folate, Folate supplementation, Folic, Folic acid, Genetic susceptibility, Gingiva, Gingival, Gingival enlargement, Gingival hyperplasia, Gingival overgrowth, Growth factor, Growth factors, Gulati, Human gingival, Hyaluronic acid, Hyperplasia, Hyperplastic gingiva, Matrix, Modeer, Oral pathol, Oral surg, Other drugs, Overgrowth, Pathol, Periodontal, Periodontol, Phenytoin, Pigo, Prostaglandin, Risk factors, Supplementation, Tumor necrosis factor.
- Teeft :
- Anatomic crowns, Anterior teeth, Broblasts, Clin periodontol, Epileptic children, Folate, Folate supplementation, Folic, Folic acid, Genetic susceptibility, Gingiva, Gingival, Gingival enlargement, Gingival hyperplasia, Gingival overgrowth, Growth factor, Growth factors, Gulati, Human gingival, Hyaluronic acid, Hyperplasia, Hyperplastic gingiva, Matrix, Modeer, Oral pathol, Oral surg, Other drugs, Overgrowth, Pathol, Periodontal, Periodontol, Phenytoin, Pigo, Prostaglandin, Risk factors, Supplementation, Tumor necrosis factor.
Abstract
Arya R, Gulati S. Phenytoin‐induced gingival overgrowth.
Acta Neurol Scand: 2012: 125: 149–155.
© 2011 John Wiley & Sons A/S. Gingival overgrowth is a common adverse effect of therapy with Phenytoin, having important medical and cosmetic implications. Poor periodontal hygiene is an important risk factor for severity of Phenytoin‐induced gingival overgrowth (PIGO), which is a time‐dependent process. There is complex interplay of altered fibroblast biology, connective tissue turnover, inflammatory processes, and growth factors on a background of genetic susceptibility to produce increase in various components of interstitial matrix in PIGO tissue. Treatment options have included change of PHT to another anti‐seizure drug, measures to improve periodontal hygiene and gingivectomy. There is conclusive evidence that folic acid supplementation significantly decreases the incidence of PIGO.
Url:
DOI: 10.1111/j.1600-0404.2011.01535.x
Affiliations:
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Phenytoin‐induced gingival overgrowth.
Acta Neurol Scand: 2012: 125: 149–155.
© 2011 John Wiley & Sons A/S. Gingival overgrowth is a common adverse effect of therapy with Phenytoin, having important medical and cosmetic implications. Poor periodontal hygiene is an important risk factor for severity of Phenytoin‐induced gingival overgrowth (PIGO), which is a time‐dependent process. There is complex interplay of altered fibroblast biology, connective tissue turnover, inflammatory processes, and growth factors on a background of genetic susceptibility to produce increase in various components of interstitial matrix in PIGO tissue. Treatment options have included change of PHT to another anti‐seizure drug, measures to improve periodontal hygiene and gingivectomy. There is conclusive evidence that folic acid supplementation significantly decreases the incidence of PIGO.</div></front></TEI><affiliations><list><country><li>Inde</li></country></list><tree><country name="Inde"><noRegion><name sortKey="Arya, R" sort="Arya, R" uniqKey="Arya R" first="R." last="Arya">R. Arya</name></noRegion><name sortKey="Gulati, S" sort="Gulati, S" uniqKey="Gulati S" first="S." last="Gulati">S. Gulati</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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