Serveur d'exploration sur le patient édenté

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Submicron Scale‐Structured Hydrophilic Titanium Surfaces Promote Early Osteogenic Gene Response for Cell Adhesion and Cell Differentiation

Identifieur interne : 002878 ( Main/Exploration ); précédent : 002877; suivant : 002879

Submicron Scale‐Structured Hydrophilic Titanium Surfaces Promote Early Osteogenic Gene Response for Cell Adhesion and Cell Differentiation

Auteurs : Marcus Oliver Klein [Allemagne] ; Ana Bijelic [Allemagne] ; Thomas Ziebart [Allemagne] ; Felix Koch [Allemagne] ; Peer W. K Mmerer [Allemagne] ; Marco Wieland [Suisse] ; Moritz A. Konerding [Allemagne] ; Bilal Al-Nawas [Allemagne]

Source :

RBID : ISTEX:89A069CB1987D0A21360D768524858F72F308781

Descripteurs français

English descriptors

Abstract

Background and Purpose: Titanium (Ti) surface roughness and surface hydrophilicity are key factors to regulate osteogenic cell responses during dental implant healing. In detail, specific integrin‐mediated interactions with the extracellular environment trigger relevant osteogenic cell responses like differentiation and matrix synthesis via transcriptions factors. Aim of this study was to monitor surface‐dependent osteogenic cell adhesion dynamics, proliferation, and specific osteogenic cell differentiation over a period of 7 days.

Url:
DOI: 10.1111/j.1708-8208.2011.00339.x


Affiliations:


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Le document en format XML

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<term>Adhesion</term>
<term>Alkaline phosphatase</term>
<term>Antisense</term>
<term>Biomed mater</term>
<term>Bone matrix proteins</term>
<term>Cell adhesion</term>
<term>Cell count</term>
<term>Cell differentiation</term>
<term>Cell number</term>
<term>Cell proliferation</term>
<term>Clinical implant dentistry</term>
<term>Collagen type</term>
<term>Dent</term>
<term>Early osteogenic cell adhesion</term>
<term>Error bars</term>
<term>Extracellular environment</term>
<term>Gapdh</term>
<term>Gene expression</term>
<term>Gene expression levels</term>
<term>Gibco invitrogen</term>
<term>High biocompatibility</term>
<term>Housekeeping genes</term>
<term>Hydrophilic surface</term>
<term>Immediate implantation</term>
<term>Implant</term>
<term>Implant surfaces</term>
<term>Integrin</term>
<term>Integrin subunits</term>
<term>Internal controls</term>
<term>Late differentiation marker</term>
<term>Mainz</term>
<term>Marcus oliver klein</term>
<term>Mater</term>
<term>Matrix</term>
<term>Matrix synthesis</term>
<term>Mature osteoblasts</term>
<term>Maxillofacial</term>
<term>Maxillofacial surgery</term>
<term>Modsla</term>
<term>Modsla surface</term>
<term>Modsla surfaces</term>
<term>Observation period</term>
<term>Oral maxillofac implants</term>
<term>Osteoblast</term>
<term>Osteoblast differentiation</term>
<term>Osteoblast growth</term>
<term>Osteogenic</term>
<term>Osteogenic cell adhesion</term>
<term>Osteogenic cell attachment</term>
<term>Osteogenic cell differentiation</term>
<term>Osteogenic cell morphology</term>
<term>Osteogenic cell response</term>
<term>Osteogenic cells</term>
<term>Osteogenic phenotype</term>
<term>Osteogenic precursors</term>
<term>Other surfaces</term>
<term>Phenotypic genes</term>
<term>Polystyrene</term>
<term>Pretreatment</term>
<term>Proc natl acad</term>
<term>Proliferation</term>
<term>Qiagen buffer</term>
<term>Radiation therapy</term>
<term>Relevant osteogenic cell responses</term>
<term>Respective substrates</term>
<term>Respective surfaces</term>
<term>Respective time points</term>
<term>Scanning transmission electron microscopy</term>
<term>Standard deviations</term>
<term>Submicron scale</term>
<term>Subunit</term>
<term>Surface hydrophilicity</term>
<term>Surface topography</term>
<term>Tcp</term>
<term>Tcps tissue culture polystyrene</term>
<term>Time point</term>
<term>Time points</term>
<term>Titanium</term>
<term>Titanium surface</term>
<term>Titanium surfaces</term>
<term>Transcription</term>
<term>Transcription factor</term>
<term>Triplet</term>
<term>University medicine mainz</term>
<term>Vivo gene expression</term>
<term>Wieland</term>
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<term>Adhesion</term>
<term>Alkaline phosphatase</term>
<term>Antisense</term>
<term>Biomed mater</term>
<term>Bone matrix proteins</term>
<term>Cell adhesion</term>
<term>Cell count</term>
<term>Cell differentiation</term>
<term>Cell number</term>
<term>Cell proliferation</term>
<term>Clinical implant dentistry</term>
<term>Collagen type</term>
<term>Dent</term>
<term>Early osteogenic cell adhesion</term>
<term>Error bars</term>
<term>Extracellular environment</term>
<term>Gapdh</term>
<term>Gene expression</term>
<term>Gene expression levels</term>
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<term>High biocompatibility</term>
<term>Housekeeping genes</term>
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<term>Immediate implantation</term>
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<term>Implant surfaces</term>
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<term>Integrin subunits</term>
<term>Internal controls</term>
<term>Late differentiation marker</term>
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<term>Matrix synthesis</term>
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<term>Maxillofacial surgery</term>
<term>Modsla</term>
<term>Modsla surface</term>
<term>Modsla surfaces</term>
<term>Observation period</term>
<term>Oral maxillofac implants</term>
<term>Osteoblast</term>
<term>Osteoblast differentiation</term>
<term>Osteoblast growth</term>
<term>Osteogenic</term>
<term>Osteogenic cell adhesion</term>
<term>Osteogenic cell attachment</term>
<term>Osteogenic cell differentiation</term>
<term>Osteogenic cell morphology</term>
<term>Osteogenic cell response</term>
<term>Osteogenic cells</term>
<term>Osteogenic phenotype</term>
<term>Osteogenic precursors</term>
<term>Other surfaces</term>
<term>Phenotypic genes</term>
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<term>Pretreatment</term>
<term>Proc natl acad</term>
<term>Proliferation</term>
<term>Qiagen buffer</term>
<term>Radiation therapy</term>
<term>Relevant osteogenic cell responses</term>
<term>Respective substrates</term>
<term>Respective surfaces</term>
<term>Respective time points</term>
<term>Scanning transmission electron microscopy</term>
<term>Standard deviations</term>
<term>Submicron scale</term>
<term>Subunit</term>
<term>Surface hydrophilicity</term>
<term>Surface topography</term>
<term>Tcp</term>
<term>Tcps tissue culture polystyrene</term>
<term>Time point</term>
<term>Time points</term>
<term>Titanium</term>
<term>Titanium surface</term>
<term>Titanium surfaces</term>
<term>Transcription</term>
<term>Transcription factor</term>
<term>Triplet</term>
<term>University medicine mainz</term>
<term>Vivo gene expression</term>
<term>Wieland</term>
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<front>
<div type="abstract">Background and Purpose: Titanium (Ti) surface roughness and surface hydrophilicity are key factors to regulate osteogenic cell responses during dental implant healing. In detail, specific integrin‐mediated interactions with the extracellular environment trigger relevant osteogenic cell responses like differentiation and matrix synthesis via transcriptions factors. Aim of this study was to monitor surface‐dependent osteogenic cell adhesion dynamics, proliferation, and specific osteogenic cell differentiation over a period of 7 days.</div>
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