Cyclosporine A up‐regulates Sonic hedgehog in gingiva: role of the up‐regulation on gingival cell proliferation
Identifieur interne : 001F95 ( Main/Exploration ); précédent : 001F94; suivant : 001F96Cyclosporine A up‐regulates Sonic hedgehog in gingiva: role of the up‐regulation on gingival cell proliferation
Auteurs : Y. Chung [République populaire de Chine] ; E. Fu [République populaire de Chine, Taïwan]Source :
- Journal of Periodontal Research [ 0022-3484 ] ; 2014-12.
Descripteurs français
- KwdFr :
- Alcaloïdes de Veratrum (pharmacologie), Animaux, Antigène nucléaire de prolifération cellulaire (), Antigène nucléaire de prolifération cellulaire (analyse), Ciclosporine (pharmacologie), Doigts de zinc (), Fibroblastes (), Gencive (), Gencive (cytologie), Humains, Lignée cellulaire, Mitogènes (pharmacologie), Modèles animaux, Mâchoire édentée (anatomopathologie), Mâle, Prolifération cellulaire (), Protéine à doigts de zinc GLI1, Protéines Hedgehog (), Protéines Hedgehog (analyse), Protéines Hedgehog (antagonistes et inhibiteurs), Protéines oncogènes (), Rat Sprague-Dawley, Rats, Régulation positive, Techniques de culture cellulaire, Transactivateurs ().
- MESH :
- analyse : Antigène nucléaire de prolifération cellulaire, Protéines Hedgehog.
- anatomopathologie : Mâchoire édentée.
- antagonistes et inhibiteurs : Protéines Hedgehog.
- cytologie : Gencive.
- pharmacologie : Alcaloïdes de Veratrum, Ciclosporine, Mitogènes.
- Animaux, Antigène nucléaire de prolifération cellulaire, Doigts de zinc, Fibroblastes, Gencive, Humains, Lignée cellulaire, Modèles animaux, Mâle, Prolifération cellulaire, Protéine à doigts de zinc GLI1, Protéines Hedgehog, Protéines oncogènes, Rat Sprague-Dawley, Rats, Régulation positive, Techniques de culture cellulaire, Transactivateurs.
English descriptors
- KwdEn :
- Animals, Cell Culture Techniques, Cell Line, Cell Proliferation (drug effects), Cyclosporine (pharmacology), Fibroblasts (drug effects), Gingiva (cytology), Gingiva (drug effects), Hedgehog Proteins (analysis), Hedgehog Proteins (antagonists & inhibitors), Hedgehog Proteins (drug effects), Humans, Jaw, Edentulous (pathology), Male, Mitogens (pharmacology), Models, Animal, Oncogene Proteins (drug effects), Proliferating Cell Nuclear Antigen (analysis), Proliferating Cell Nuclear Antigen (drug effects), Rats, Rats, Sprague-Dawley, Trans-Activators (drug effects), Up-Regulation, Veratrum Alkaloids (pharmacology), Zinc Finger Protein GLI1, Zinc Fingers (drug effects).
- MESH :
- chemical , analysis : Hedgehog Proteins, Proliferating Cell Nuclear Antigen.
- chemical , antagonists & inhibitors : Hedgehog Proteins.
- chemical , drug effects : Hedgehog Proteins, Oncogene Proteins, Proliferating Cell Nuclear Antigen, Trans-Activators.
- chemical , pharmacology : Cyclosporine, Mitogens, Veratrum Alkaloids.
- cytology : Gingiva.
- drug effects : Cell Proliferation, Fibroblasts, Gingiva, Zinc Fingers.
- pathology : Jaw, Edentulous.
- Animals, Cell Culture Techniques, Cell Line, Humans, Male, Models, Animal, Rats, Rats, Sprague-Dawley, Up-Regulation, Zinc Finger Protein GLI1.
Abstract
Sonic hedgehog protein (SHH) is a mitogen that stimulates cell proliferation. Cyclosporine A enhances the proliferation of gingival cells; however, the relationships of SHH to cyclosporine A or to cyclosporine A‐enhanced gingival cell proliferation have not been described.
Url:
DOI: 10.1111/jre.12168
Affiliations:
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Le document en format XML
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Edentulous</term></keywords><keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Alcaloïdes de Veratrum</term><term>Ciclosporine</term><term>Mitogènes</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Cell Culture Techniques</term><term>Cell Line</term><term>Humans</term><term>Male</term><term>Models, Animal</term><term>Rats</term><term>Rats, Sprague-Dawley</term><term>Up-Regulation</term><term>Zinc Finger Protein GLI1</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Antigène nucléaire de prolifération cellulaire</term><term>Doigts de zinc</term><term>Fibroblastes</term><term>Gencive</term><term>Humains</term><term>Lignée cellulaire</term><term>Modèles animaux</term><term>Mâle</term><term>Prolifération cellulaire</term><term>Protéine à doigts de zinc GLI1</term><term>Protéines Hedgehog</term><term>Protéines oncogènes</term><term>Rat Sprague-Dawley</term><term>Rats</term><term>Régulation positive</term><term>Techniques de culture cellulaire</term><term>Transactivateurs</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract">Sonic hedgehog protein (SHH) is a mitogen that stimulates cell proliferation. Cyclosporine A enhances the proliferation of gingival cells; however, the relationships of SHH to cyclosporine A or to cyclosporine A‐enhanced gingival cell proliferation have not been described.</div></front></TEI><affiliations><list><country><li>République populaire de Chine</li><li>Taïwan</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Chung, Y" sort="Chung, Y" uniqKey="Chung Y" first="Y." last="Chung">Y. Chung</name></noRegion><name sortKey="Chung, Y" sort="Chung, Y" uniqKey="Chung Y" first="Y." last="Chung">Y. Chung</name><name sortKey="Fu, E" sort="Fu, E" uniqKey="Fu E" first="E." last="Fu">E. Fu</name><name sortKey="Fu, E" sort="Fu, E" uniqKey="Fu E" first="E." last="Fu">E. Fu</name></country><country name="Taïwan"><noRegion><name sortKey="Fu, E" sort="Fu, E" uniqKey="Fu E" first="E." last="Fu">E. Fu</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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