Risk Assessment of BRONJ in Oncologic Patients Treated with Bisphosphonates: Follow-Up to 18 Months
Identifieur interne : 001738 ( Main/Exploration ); précédent : 001737; suivant : 001739Risk Assessment of BRONJ in Oncologic Patients Treated with Bisphosphonates: Follow-Up to 18 Months
Auteurs : Scilla Sparabombe [Italie] ; Lucia Vitali [Italie] ; Alessandra Nori [Italie] ; Ricarda Sara Berlin [Italie] ; Marta Mazur [Italie] ; Giovanna Orsini [Italie] ; Angelo Putignano [Italie]Source :
- International Journal of Dentistry [ 1687-8728 ] ; 2014.
Abstract
Url:
DOI: 10.1155/2014/475859
PubMed: 25258628
PubMed Central: 4167445
Affiliations:
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S" first="Scilla" last="Sparabombe">Scilla Sparabombe</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Clinical Sciences and Stomatology, Faculty of Medicine, Polytechnic University of Marche, Palace “Murri”, Floor No. 3, Via Tronto 10, 60126 Ancona, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Sciences and Stomatology, Faculty of Medicine, Polytechnic University of Marche, Palace “Murri”, Floor No. 3, Via Tronto 10, 60126 Ancona</wicri:regionArea><wicri:noRegion>60126 Ancona</wicri:noRegion></affiliation></author><author><name sortKey="Vitali, Lucia" sort="Vitali, Lucia" uniqKey="Vitali L" first="Lucia" last="Vitali">Lucia Vitali</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Clinical Sciences and Stomatology, Faculty of Medicine, Polytechnic University of Marche, Palace “Murri”, Floor No. 3, Via Tronto 10, 60126 Ancona, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Sciences and Stomatology, Faculty of Medicine, Polytechnic University of Marche, Palace “Murri”, Floor No. 3, Via Tronto 10, 60126 Ancona</wicri:regionArea><wicri:noRegion>60126 Ancona</wicri:noRegion></affiliation></author><author><name sortKey="Nori, Alessandra" sort="Nori, Alessandra" uniqKey="Nori A" first="Alessandra" last="Nori">Alessandra Nori</name><affiliation wicri:level="1"><nlm:aff id="I2">Special and Surgical Stomatology Department, “Ospedali Riuniti” Hospital of Ancona, Via Conca 2, 60126 Ancona, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Special and Surgical Stomatology Department, “Ospedali Riuniti” Hospital of Ancona, Via Conca 2, 60126 Ancona</wicri:regionArea><wicri:noRegion>60126 Ancona</wicri:noRegion></affiliation></author><author><name sortKey="Berlin, Ricarda Sara" sort="Berlin, Ricarda Sara" uniqKey="Berlin R" first="Ricarda Sara" last="Berlin">Ricarda Sara Berlin</name><affiliation wicri:level="1"><nlm:aff id="I2">Special and Surgical Stomatology Department, “Ospedali Riuniti” Hospital of Ancona, Via Conca 2, 60126 Ancona, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Special and Surgical Stomatology Department, “Ospedali Riuniti” Hospital of Ancona, Via Conca 2, 60126 Ancona</wicri:regionArea><wicri:noRegion>60126 Ancona</wicri:noRegion></affiliation></author><author><name sortKey="Mazur, Marta" sort="Mazur, Marta" uniqKey="Mazur M" first="Marta" last="Mazur">Marta Mazur</name><affiliation wicri:level="1"><nlm:aff id="I3">Stomatology and Maxillofacial Science Department, University of Rome “La Sapienza”, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Stomatology and Maxillofacial Science Department, University of Rome “La Sapienza”</wicri:regionArea><wicri:noRegion>University of Rome “La Sapienza”</wicri:noRegion></affiliation></author><author><name sortKey="Orsini, Giovanna" sort="Orsini, Giovanna" uniqKey="Orsini G" first="Giovanna" last="Orsini">Giovanna Orsini</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Clinical Sciences and Stomatology, Faculty of Medicine, Polytechnic University of Marche, Palace “Murri”, Floor No. 3, Via Tronto 10, 60126 Ancona, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Sciences and Stomatology, Faculty of Medicine, Polytechnic University of Marche, Palace “Murri”, Floor No. 3, Via Tronto 10, 60126 Ancona</wicri:regionArea><wicri:noRegion>60126 Ancona</wicri:noRegion></affiliation></author><author><name sortKey="Putignano, Angelo" sort="Putignano, Angelo" uniqKey="Putignano A" first="Angelo" last="Putignano">Angelo Putignano</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Clinical Sciences and Stomatology, Faculty of Medicine, Polytechnic University of Marche, Palace “Murri”, Floor No. 3, Via Tronto 10, 60126 Ancona, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Sciences and Stomatology, Faculty of Medicine, Polytechnic University of Marche, Palace “Murri”, Floor No. 3, Via Tronto 10, 60126 Ancona</wicri:regionArea><wicri:noRegion>60126 Ancona</wicri:noRegion></affiliation></author></analytic><series><title level="j">International Journal of Dentistry</title><idno type="ISSN">1687-8728</idno><idno type="eISSN">1687-8736</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><italic>Objectives.</italic> Bisphosphonates related osteonecrosis of the jaw (BRONJ) is a pathological condition characterized by bone exposure or latent infection in patients treated with the drug. The aim of the study is to monitor the BRONJ level of risk health in patients with cancer, according to a preventive clinical protocol, which is firstly aimed at reducing risk factors such as the periodontal infections.
<italic>Materials and Methods.</italic> 10 patients participated in the protocol and were evaluated at baseline and after 3 and 18 months of treatment with bisphosphonates, through full mouth plaque and bleeding scores (FMPS and FMBS), clinical attachment level (CAL) measurement, and the occurrence of osteonecrosis. <italic>Results.</italic> The mean plaque and bleeding were reduced and the CAL has not shown significant changes and in no cases was there manifestation of BRONJ. <italic>Conclusion.</italic> The protocol proved crucial for the maintenance of good oral health conditions by eliminating the risk of BRONJ during the observation period.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Hillner, Be" uniqKey="Hillner B">BE Hillner</name></author><author><name sortKey="Ingle, Jn" uniqKey="Ingle J">JN Ingle</name></author><author><name sortKey="Berenson, Jr" uniqKey="Berenson J">JR 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Marx</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Krebs, Ka" uniqKey="Krebs K">KA Krebs</name></author><author><name sortKey="Clem, Ds" uniqKey="Clem D">DS Clem</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Durie, Bgm" uniqKey="Durie B">BGM Durie</name></author><author><name sortKey="Katz, M" uniqKey="Katz M">M Katz</name></author><author><name sortKey="Crowley, J" uniqKey="Crowley J">J Crowley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Marx, Re" uniqKey="Marx R">RE Marx</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hoff, Ao" uniqKey="Hoff A">AO Hoff</name></author><author><name sortKey="Toth, Bb" uniqKey="Toth B">BB Toth</name></author><author><name sortKey="Altundag, K" uniqKey="Altundag K">K Altundag</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Italie</li></country></list><tree><country name="Italie"><noRegion><name sortKey="Sparabombe, Scilla" sort="Sparabombe, Scilla" uniqKey="Sparabombe S" first="Scilla" last="Sparabombe">Scilla Sparabombe</name></noRegion><name sortKey="Berlin, Ricarda Sara" sort="Berlin, Ricarda Sara" uniqKey="Berlin R" first="Ricarda Sara" last="Berlin">Ricarda Sara Berlin</name><name sortKey="Mazur, Marta" sort="Mazur, Marta" uniqKey="Mazur M" first="Marta" last="Mazur">Marta Mazur</name><name sortKey="Nori, Alessandra" sort="Nori, Alessandra" uniqKey="Nori A" first="Alessandra" last="Nori">Alessandra Nori</name><name sortKey="Orsini, Giovanna" sort="Orsini, Giovanna" uniqKey="Orsini G" first="Giovanna" last="Orsini">Giovanna Orsini</name><name sortKey="Putignano, Angelo" sort="Putignano, Angelo" uniqKey="Putignano A" first="Angelo" last="Putignano">Angelo Putignano</name><name sortKey="Vitali, Lucia" sort="Vitali, Lucia" uniqKey="Vitali L" first="Lucia" last="Vitali">Lucia Vitali</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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