EdenteV2, Main, Exploration, bibRecord, 001585

Validation of dental X-ray by cytokine RANTES – comparison of X-ray findings with cytokine overexpression in jawbone

Identifieur interne : 001585 ( Main/Exploration ); précédent : 001584; suivant : 001586

Validation of dental X-ray by cytokine RANTES – comparison of X-ray findings with cytokine overexpression in jawbone

Auteurs : Johann Lechner [Allemagne]

Source :

Clinical, Cosmetic and Investigational Dentistry [ 1179-1357 ] ; 2014.

RBID : PMC:4144985

Abstract

Introduction

There is a need to clarify the extent to which the most common diagnostic tool in dentistry – two-dimensional panoramic tomography (2D-OPG) – is suitable for identifying fatty degenerative osteolysis of jawbone (FDOJ).

Materials and methods

To obtain a qualitative assessment of edentulous jawbone sections, the results from 2D-OPG with a defined X-ray density (XrDn), expression of the cytokine RANTES (regulated on activation, normal T-cell expressed and secreted), and a transalveolar ultrasound system for measuring jawbone density were compared.

Results

The difference in the XrDn of healthy jawbone and FDOJ are minimal, whereas RANTES is up to 25-fold higher in FDOJ. In contrast to 2D-OPG, transalveolar ultrasound showed coincidental findings in FDOJ areas.

Discussion

Comparisons of the data revealed a discrepancy between the XrDn of 2D-OPGs and the medullary osteopathies in the jawbone like FDOJ.

Conclusion

The data suggest that there is a critical attitude toward the use of 2D-OPG as a sole imaging diagnostic tool for assessing chronic inflammatory processes in the jawbone. Specifically, 2D-OPG is objectively not suitable for depicting FDOJ.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144985

DOI: 10.2147/CCIDE.S69807
PubMed: 25170282
PubMed Central: 4144985

Affiliations:

Le document en format XML

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<author><name sortKey="Lechner, Johann" sort="Lechner, Johann" uniqKey="Lechner J" first="Johann" last="Lechner">Johann Lechner</name>
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<front><div type="abstract" xml:lang="en"><sec><title>Introduction</title>
<p>There is a need to clarify the extent to which the most common diagnostic tool in dentistry – two-dimensional panoramic tomography (2D-OPG) – is suitable for identifying fatty degenerative osteolysis of jawbone (FDOJ).</p>
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<sec><title>Materials and methods</title>
<p>To obtain a qualitative assessment of edentulous jawbone sections, the results from 2D-OPG with a defined X-ray density (XrDn), expression of the cytokine RANTES (regulated on activation, normal T-cell expressed and secreted), and a transalveolar ultrasound system for measuring jawbone density were compared.</p>
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<sec><title>Results</title>
<p>The difference in the XrDn of healthy jawbone and FDOJ are minimal, whereas RANTES is up to 25-fold higher in FDOJ. In contrast to 2D-OPG, transalveolar ultrasound showed coincidental findings in FDOJ areas.</p>
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<sec><title>Discussion</title>
<p>Comparisons of the data revealed a discrepancy between the XrDn of 2D-OPGs and the medullary osteopathies in the jawbone like FDOJ.</p>
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<sec><title>Conclusion</title>
<p>The data suggest that there is a critical attitude toward the use of 2D-OPG as a sole imaging diagnostic tool for assessing chronic inflammatory processes in the jawbone. Specifically, 2D-OPG is objectively not suitable for depicting FDOJ.</p>
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Validation of dental X-ray by cytokine RANTES – comparison of X-ray findings with cytokine overexpression in jawbone

Validation of dental X-ray by cytokine RANTES – comparison of X-ray findings with cytokine overexpression in jawbone

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