Serveur d'exploration sur le patient édenté

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Oral behavior, dental, periodontal and microbiological findings in patients undergoing hemodialysis and after kidney transplantation

Identifieur interne : 000646 ( Main/Exploration ); précédent : 000645; suivant : 000647

Oral behavior, dental, periodontal and microbiological findings in patients undergoing hemodialysis and after kidney transplantation

Auteurs : Gerhard Schmalz [Allemagne] ; Anne Kauffels [Allemagne] ; Otto Kollmar [Allemagne] ; Jan E. Slotta [Allemagne] ; Radovan Vasko [Allemagne] ; Gerhard A. Müller [Allemagne] ; Rainer Haak [Allemagne] ; Dirk Ziebolz [Allemagne]

Source :

RBID : PMC:4988025

Abstract

Background

Aim of this single center cross-sectional study was to investigate oral behavior, dental, periodontal and microbiological findings in patients undergoing hemodialysis (HD) and after kidney transplantation (KT).

Methods

Patients undergoing HD for end-stage renal failure and after KT were investigated. Oral health behavior was recorded using a standardized questionnaire, e.g. dental behavior, tooth brushing, oral hygiene aids. Oral investigation included screening of oral mucosa, dental findings (DMF-T) and periodontal situation (Papilla bleeding index [PBI] periodontal probing depth [PPD] and clinical attachment loss [CAL]). Additionally, microbiological analysis of subgingival biofilm samples (PCR) was performed. Statistical analysis: Student’s t-test or Mann–Whitney-U-test, Fisher’s exact test (α = 5 %).

Results

A total of 70 patients (HD: n = 35, KT: n = 35) with a mean age of 56.4 ± 11.1 (HD) and 55.8 ± 10.9 (KT) years were included. Lack in use of additional oral hygiene (dental floss, inter-dental brush) was found. KT group presented significantly more gingivial overgrowth (p = 0.01). DMF-T was 19.47 ± 5.84 (HD) and 17.61 ± 5.81 (KT; p = 0.21). Majority of patients had clinically moderate and severe periodontitis; showing a need for periodontal treatment of 57 % (HD) and 71 % (KT; p = 0.30). Significantly higher prevalence of Parvimonas micra and Capnocytophaga species in the HD group were found (p < 0.01).

Conclusion

Periodontal treatment need and lack in oral behavior for both groups indicate the necessity of an improved early treatment and prevention of dental and periodontal disease, e.g. in form of special care programs. Regarding microbiological findings, no major differences between KT and HD patients were found.


Url:
DOI: 10.1186/s12903-016-0274-0
PubMed: 27531498
PubMed Central: 4988025


Affiliations:


Links toward previous steps (curation, corpus...)


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<name sortKey="Vasko, Radovan" sort="Vasko, Radovan" uniqKey="Vasko R" first="Radovan" last="Vasko">Radovan Vasko</name>
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<wicri:noRegion>Goettingen</wicri:noRegion>
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<name sortKey="Haak, Rainer" sort="Haak, Rainer" uniqKey="Haak R" first="Rainer" last="Haak">Rainer Haak</name>
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<nlm:aff id="Aff1">Department of Cariology, Endodontology and Periodontology, University of Leipzig, Liebigstr. 10-14, D 04103 Leipzig, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
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<region type="district" nuts="2">District de Leipzig</region>
<settlement type="city">Leipzig</settlement>
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<name sortKey="Ziebolz, Dirk" sort="Ziebolz, Dirk" uniqKey="Ziebolz D" first="Dirk" last="Ziebolz">Dirk Ziebolz</name>
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<nlm:aff id="Aff1">Department of Cariology, Endodontology and Periodontology, University of Leipzig, Liebigstr. 10-14, D 04103 Leipzig, Germany</nlm:aff>
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<region type="district" nuts="2">District de Leipzig</region>
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<div type="abstract" xml:lang="en">
<sec>
<title>Background</title>
<p>Aim of this single center cross-sectional study was to investigate oral behavior, dental, periodontal and microbiological findings in patients undergoing hemodialysis (HD) and after kidney transplantation (KT).</p>
</sec>
<sec>
<title>Methods</title>
<p>Patients undergoing HD for end-stage renal failure and after KT were investigated. Oral health behavior was recorded using a standardized questionnaire, e.g. dental behavior, tooth brushing, oral hygiene aids. Oral investigation included screening of oral mucosa, dental findings (DMF-T) and periodontal situation (Papilla bleeding index [PBI] periodontal probing depth [PPD] and clinical attachment loss [CAL]). Additionally, microbiological analysis of subgingival biofilm samples (PCR) was performed. Statistical analysis: Student’s
<italic>t</italic>
-test or Mann–Whitney-
<italic>U</italic>
-test, Fisher’s exact test (α = 5 %).</p>
</sec>
<sec>
<title>Results</title>
<p>A total of 70 patients (HD:
<italic>n</italic>
 = 35, KT:
<italic>n</italic>
 = 35) with a mean age of 56.4 ± 11.1 (HD) and 55.8 ± 10.9 (KT) years were included. Lack in use of additional oral hygiene (dental floss, inter-dental brush) was found. KT group presented significantly more gingivial overgrowth (
<italic>p</italic>
 = 0.01). DMF-T was 19.47 ± 5.84 (HD) and 17.61 ± 5.81 (KT;
<italic>p</italic>
 = 0.21). Majority of patients had clinically moderate and severe periodontitis; showing a need for periodontal treatment of 57 % (HD) and 71 % (KT;
<italic>p</italic>
 = 0.30). Significantly higher prevalence of
<italic>Parvimonas micra</italic>
and
<italic>Capnocytophaga species</italic>
in the HD group were found (
<italic>p</italic>
 < 0.01).</p>
</sec>
<sec>
<title>Conclusion</title>
<p>Periodontal treatment need and lack in oral behavior for both groups indicate the necessity of an improved early treatment and prevention of dental and periodontal disease, e.g. in form of special care programs. Regarding microbiological findings, no major differences between KT and HD patients were found.</p>
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<list>
<country>
<li>Allemagne</li>
</country>
<region>
<li>District de Leipzig</li>
<li>Saxe (Land)</li>
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<li>Leipzig</li>
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<name sortKey="Schmalz, Gerhard" sort="Schmalz, Gerhard" uniqKey="Schmalz G" first="Gerhard" last="Schmalz">Gerhard Schmalz</name>
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<name sortKey="Kauffels, Anne" sort="Kauffels, Anne" uniqKey="Kauffels A" first="Anne" last="Kauffels">Anne Kauffels</name>
<name sortKey="Kollmar, Otto" sort="Kollmar, Otto" uniqKey="Kollmar O" first="Otto" last="Kollmar">Otto Kollmar</name>
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<name sortKey="Muller, Gerhard A" sort="Muller, Gerhard A" uniqKey="Muller G" first="Gerhard A." last="Müller">Gerhard A. Müller</name>
<name sortKey="Slotta, Jan E" sort="Slotta, Jan E" uniqKey="Slotta J" first="Jan E." last="Slotta">Jan E. Slotta</name>
<name sortKey="Slotta, Jan E" sort="Slotta, Jan E" uniqKey="Slotta J" first="Jan E." last="Slotta">Jan E. Slotta</name>
<name sortKey="Vasko, Radovan" sort="Vasko, Radovan" uniqKey="Vasko R" first="Radovan" last="Vasko">Radovan Vasko</name>
<name sortKey="Ziebolz, Dirk" sort="Ziebolz, Dirk" uniqKey="Ziebolz D" first="Dirk" last="Ziebolz">Dirk Ziebolz</name>
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</record>

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