Primary malignant melanoma of oral cavity: A report of three rare cases
Identifieur interne : 000583 ( Main/Exploration ); précédent : 000582; suivant : 000584Primary malignant melanoma of oral cavity: A report of three rare cases
Auteurs : Hanspal Singh ; Priya Kumar ; Jeyaseelan Augustine ; Aadithya B. Urs ; Sunita GuptaSource :
- Contemporary Clinical Dentistry [ 0976-237X ] ; 2016.
Abstract
Oral malignant melanoma (OMM) is a rare tumor of melanocytic origin, accounting for 20–30% of malignant melanomas at the mucosal surface and 16% intra-orally. Hard palate and maxillary gingiva are the most common involved sites. In this case series, we present varying patterns of presentation of three cases of OMM with one case of distant metastasis. All cases in the current series presented at an advanced stage and died within a year of diagnosis. In conclusion, due to the aggressive clinical course and poor prognosis of this deadly lesion, it is of paramount importance to maintain a high index of suspicion for early detection and diagnosis for any pigmented lesion in the oral cavity.
Url:
DOI: 10.4103/0976-237X.177094
PubMed: 27041909
PubMed Central: 4792064
Affiliations:
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Urs</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Gupta, Sunita" sort="Gupta, Sunita" uniqKey="Gupta S" first="Sunita" last="Gupta">Sunita Gupta</name><affiliation><nlm:aff id="aff2"><italic>Department of Oral Medicine and Radiology, Maulana Azad Institute of Dental Sciences, New Delhi, India</italic></nlm:aff></affiliation></author></analytic><series><title level="j">Contemporary Clinical Dentistry</title><idno type="ISSN">0976-237X</idno><idno type="eISSN">0976-2361</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Oral malignant melanoma (OMM) is a rare tumor of melanocytic origin, accounting for 20–30% of malignant melanomas at the mucosal surface and 16% intra-orally. Hard palate and maxillary gingiva are the most common involved sites. In this case series, we present varying patterns of presentation of three cases of OMM with one case of distant metastasis. All cases in the current series presented at an advanced stage and died within a year of diagnosis. In conclusion, due to the aggressive clinical course and poor prognosis of this deadly lesion, it is of paramount importance to maintain a high index of suspicion for early detection and diagnosis for any pigmented lesion in the oral cavity.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Auluck, A" uniqKey="Auluck A">A Auluck</name></author><author><name sortKey="Zhang, L" uniqKey="Zhang L">L Zhang</name></author><author><name sortKey="Desai, R" uniqKey="Desai R">R Desai</name></author><author><name sortKey="Rosin, Mp" uniqKey="Rosin M">MP Rosin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hashemi Pour, Ms" uniqKey="Hashemi Pour M">MS Hashemi Pour</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Umeda, M" uniqKey="Umeda M">M Umeda</name></author><author><name sortKey="Komatsubara, H" uniqKey="Komatsubara H">H Komatsubara</name></author><author><name sortKey="Shigeta, T" uniqKey="Shigeta T">T Shigeta</name></author><author><name sortKey="Ojima, Y" uniqKey="Ojima Y">Y Ojima</name></author><author><name sortKey="Minamikawa, T" uniqKey="Minamikawa T">T Minamikawa</name></author><author><name sortKey="Shibuya, Y" uniqKey="Shibuya Y">Y Shibuya</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tanaka, N" uniqKey="Tanaka N">N Tanaka</name></author><author><name sortKey="Mimura, M" uniqKey="Mimura M">M Mimura</name></author><author><name sortKey="Ogi, K" uniqKey="Ogi K">K Ogi</name></author><author><name sortKey="Amagasa, T" uniqKey="Amagasa T">T Amagasa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barker, Bf" uniqKey="Barker B">BF Barker</name></author><author><name sortKey="Carpenter, Wm" uniqKey="Carpenter W">WM Carpenter</name></author><author><name sortKey="Daniels, Te" uniqKey="Daniels T">TE Daniels</name></author><author><name sortKey="Kahn, Ma" uniqKey="Kahn M">MA Kahn</name></author><author><name sortKey="Leider, As" uniqKey="Leider A">AS Leider</name></author><author><name sortKey="Lozada Nur, F" uniqKey="Lozada Nur F">F Lozada-Nur</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rosenberg, Sa" uniqKey="Rosenberg S">SA Rosenberg</name></author><author><name sortKey="Lotze, Mt" uniqKey="Lotze M">MT Lotze</name></author><author><name sortKey="Muul, Lm" uniqKey="Muul L">LM Muul</name></author><author><name sortKey="Leitman, S" uniqKey="Leitman S">S Leitman</name></author><author><name sortKey="Chang, Ae" uniqKey="Chang A">AE Chang</name></author><author><name sortKey="Ettinghausen, Se" uniqKey="Ettinghausen S">SE Ettinghausen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ebenezer, J" uniqKey="Ebenezer J">J Ebenezer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lucas, Rb" uniqKey="Lucas R">RB Lucas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Marx, Re" uniqKey="Marx R">RE Marx</name></author><author><name sortKey="Stern, D" uniqKey="Stern D">D Stern</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list></list><tree><noCountry><name sortKey="Augustine, Jeyaseelan" sort="Augustine, Jeyaseelan" uniqKey="Augustine J" first="Jeyaseelan" last="Augustine">Jeyaseelan Augustine</name><name sortKey="Gupta, Sunita" sort="Gupta, Sunita" uniqKey="Gupta S" first="Sunita" last="Gupta">Sunita Gupta</name><name sortKey="Kumar, Priya" sort="Kumar, Priya" uniqKey="Kumar P" first="Priya" last="Kumar">Priya Kumar</name><name sortKey="Singh, Hanspal" sort="Singh, Hanspal" uniqKey="Singh H" first="Hanspal" last="Singh">Hanspal Singh</name><name sortKey="Urs, Aadithya B" sort="Urs, Aadithya B" uniqKey="Urs A" first="Aadithya B." last="Urs">Aadithya B. 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