Evaluation of Correlation between Salivary Calcium, Alkaline Phosphatase and Osteoporosis- A Prospective, Comparative and Observational Study
Identifieur interne : 000259 ( Main/Exploration ); précédent : 000258; suivant : 000260Evaluation of Correlation between Salivary Calcium, Alkaline Phosphatase and Osteoporosis- A Prospective, Comparative and Observational Study
Auteurs : Mainak Kanti Saha ; Prerna Agrawal ; Suparna Ganguly Saha ; Vinod Vishwanathan ; Vandana Pathak ; Sakuru Venkata Saiprasad ; Purvi Dhariwal ; Mahendra DaveSource :
- Journal of Clinical and Diagnostic Research : JCDR [ 2249-782X ] ; 2017.
Abstract
Fixed and/or removable prosthodontics caters to the restorative needs of the largest count of geriatric patients whose rehabilitative procedures depend on the quality and quantity of available bone. The common diagnostic parameters for quantifying bone may involve an invasive blood examination, an expensive bone densitometry procedure or a urine analysis. Sialometry involving the basic biochemistry of saliva analysis may be proposed as an alternative to the conventional investigative protocol and its usefulness may be attributed owing to its non invasive and simpler procedure.
The aim of this study was to compare the salivary calcium and alkaline phosphatase among osteoporotic, osteopenic and normal edentulous subjects.
A prospective, comparative and observational study was carried out on 80 selected edentulous subjects (40 males and 40 females) aged 55-75 years (30 osteoporotic, 30 osteopenic and 20 control). A sample of saliva was taken for the study. Salivary calcium was measured by Arsenazo reaction; and alkaline phosphatase by the International Federation of Clinical Chemistry (IFCC) method. Statistical analysis was done by unpaired t-test. A comparison was made in the levels of salivary calcium and alkaline phosphatase with that of osteoporosis and osteopenia.
The mean salivary calcium and alkaline phosphatase levels were found to be significantly higher in the osteoporotic and osteopenic edentulous subjects as compared to the control group.
Salivary calcium and alkaline phosphatase are increased significantly in case of osteoporosis and osteopenia. Hence, screening of salivary samples of patients may be an effective indicator for the detection of underlying disorders of bone metabolism.
Url:
DOI: 10.7860/JCDR/2017/24960.9583
PubMed: 28511512
PubMed Central: 5427438
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 002402
- to stream Pmc, to step Curation: 002402
- to stream Pmc, to step Checkpoint: 000238
- to stream Ncbi, to step Merge: 006F89
- to stream Ncbi, to step Curation: 006F89
- to stream Ncbi, to step Checkpoint: 006F89
- to stream Main, to step Merge: 000259
- to stream Main, to step Curation: 000259
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Evaluation of Correlation between Salivary Calcium, Alkaline Phosphatase and Osteoporosis- A Prospective, Comparative and Observational Study</title>
<author><name sortKey="Saha, Mainak Kanti" sort="Saha, Mainak Kanti" uniqKey="Saha M" first="Mainak Kanti" last="Saha">Mainak Kanti Saha</name>
<affiliation><nlm:aff id="aff1"> Professor and Head, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Agrawal, Prerna" sort="Agrawal, Prerna" uniqKey="Agrawal P" first="Prerna" last="Agrawal">Prerna Agrawal</name>
<affiliation><nlm:aff id="aff2"> Postgraduate Student, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Pithampur, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Saha, Suparna Ganguly" sort="Saha, Suparna Ganguly" uniqKey="Saha S" first="Suparna Ganguly" last="Saha">Suparna Ganguly Saha</name>
<affiliation><nlm:aff id="aff3"> Professor and Head, Department of Conservative Dentistry,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Vishwanathan, Vinod" sort="Vishwanathan, Vinod" uniqKey="Vishwanathan V" first="Vinod" last="Vishwanathan">Vinod Vishwanathan</name>
<affiliation><nlm:aff id="aff4"> Reader, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Pathak, Vandana" sort="Pathak, Vandana" uniqKey="Pathak V" first="Vandana" last="Pathak">Vandana Pathak</name>
<affiliation><nlm:aff id="aff5"> Senior Lecturer, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Saiprasad, Sakuru Venkata" sort="Saiprasad, Sakuru Venkata" uniqKey="Saiprasad S" first="Sakuru Venkata" last="Saiprasad">Sakuru Venkata Saiprasad</name>
<affiliation><nlm:aff id="aff6"> Principal Scientist, Indian Council of Agricultural Research,<institution>Indian Agricultural Research Institute</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Dhariwal, Purvi" sort="Dhariwal, Purvi" uniqKey="Dhariwal P" first="Purvi" last="Dhariwal">Purvi Dhariwal</name>
<affiliation><nlm:aff id="aff7"> Postgraduate Student, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Dave, Mahendra" sort="Dave, Mahendra" uniqKey="Dave M" first="Mahendra" last="Dave">Mahendra Dave</name>
<affiliation><nlm:aff id="aff8"> Postgraduate Student, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">28511512</idno>
<idno type="pmc">5427438</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427438</idno>
<idno type="RBID">PMC:5427438</idno>
<idno type="doi">10.7860/JCDR/2017/24960.9583</idno>
<date when="2017">2017</date>
<idno type="wicri:Area/Pmc/Corpus">002402</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002402</idno>
<idno type="wicri:Area/Pmc/Curation">002402</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002402</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000238</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000238</idno>
<idno type="wicri:Area/Ncbi/Merge">006F89</idno>
<idno type="wicri:Area/Ncbi/Curation">006F89</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">006F89</idno>
<idno type="wicri:doubleKey">2249-782X:2017:Saha M:evaluation:of:correlation</idno>
<idno type="wicri:Area/Main/Merge">000259</idno>
<idno type="wicri:Area/Main/Curation">000259</idno>
<idno type="wicri:Area/Main/Exploration">000259</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Evaluation of Correlation between Salivary Calcium, Alkaline Phosphatase and Osteoporosis- A Prospective, Comparative and Observational Study</title>
<author><name sortKey="Saha, Mainak Kanti" sort="Saha, Mainak Kanti" uniqKey="Saha M" first="Mainak Kanti" last="Saha">Mainak Kanti Saha</name>
<affiliation><nlm:aff id="aff1"> Professor and Head, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Agrawal, Prerna" sort="Agrawal, Prerna" uniqKey="Agrawal P" first="Prerna" last="Agrawal">Prerna Agrawal</name>
<affiliation><nlm:aff id="aff2"> Postgraduate Student, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Pithampur, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Saha, Suparna Ganguly" sort="Saha, Suparna Ganguly" uniqKey="Saha S" first="Suparna Ganguly" last="Saha">Suparna Ganguly Saha</name>
<affiliation><nlm:aff id="aff3"> Professor and Head, Department of Conservative Dentistry,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Vishwanathan, Vinod" sort="Vishwanathan, Vinod" uniqKey="Vishwanathan V" first="Vinod" last="Vishwanathan">Vinod Vishwanathan</name>
<affiliation><nlm:aff id="aff4"> Reader, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Pathak, Vandana" sort="Pathak, Vandana" uniqKey="Pathak V" first="Vandana" last="Pathak">Vandana Pathak</name>
<affiliation><nlm:aff id="aff5"> Senior Lecturer, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Saiprasad, Sakuru Venkata" sort="Saiprasad, Sakuru Venkata" uniqKey="Saiprasad S" first="Sakuru Venkata" last="Saiprasad">Sakuru Venkata Saiprasad</name>
<affiliation><nlm:aff id="aff6"> Principal Scientist, Indian Council of Agricultural Research,<institution>Indian Agricultural Research Institute</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Dhariwal, Purvi" sort="Dhariwal, Purvi" uniqKey="Dhariwal P" first="Purvi" last="Dhariwal">Purvi Dhariwal</name>
<affiliation><nlm:aff id="aff7"> Postgraduate Student, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Dave, Mahendra" sort="Dave, Mahendra" uniqKey="Dave M" first="Mahendra" last="Dave">Mahendra Dave</name>
<affiliation><nlm:aff id="aff8"> Postgraduate Student, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Journal of Clinical and Diagnostic Research : JCDR</title>
<idno type="ISSN">2249-782X</idno>
<idno type="eISSN">0973-709X</idno>
<imprint><date when="2017">2017</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec><title>Introduction</title>
<p>Fixed and/or removable prosthodontics caters to the restorative needs of the largest count of geriatric patients whose rehabilitative procedures depend on the quality and quantity of available bone. The common diagnostic parameters for quantifying bone may involve an invasive blood examination, an expensive bone densitometry procedure or a urine analysis. Sialometry involving the basic biochemistry of saliva analysis may be proposed as an alternative to the conventional investigative protocol and its usefulness may be attributed owing to its non invasive and simpler procedure.</p>
</sec>
<sec><title>Aim</title>
<p>The aim of this study was to compare the salivary calcium and alkaline phosphatase among osteoporotic, osteopenic and normal edentulous subjects.</p>
</sec>
<sec><title>Materials and Methods</title>
<p>A prospective, comparative and observational study was carried out on 80 selected edentulous subjects (40 males and 40 females) aged 55-75 years (30 osteoporotic, 30 osteopenic and 20 control). A sample of saliva was taken for the study. Salivary calcium was measured by Arsenazo reaction; and alkaline phosphatase by the International Federation of Clinical Chemistry (IFCC) method. Statistical analysis was done by unpaired t-test. A comparison was made in the levels of salivary calcium and alkaline phosphatase with that of osteoporosis and osteopenia.</p>
</sec>
<sec><title>Results</title>
<p>The mean salivary calcium and alkaline phosphatase levels were found to be significantly higher in the osteoporotic and osteopenic edentulous subjects as compared to the control group.</p>
</sec>
<sec><title>Conclusion</title>
<p>Salivary calcium and alkaline phosphatase are increased significantly in case of osteoporosis and osteopenia. Hence, screening of salivary samples of patients may be an effective indicator for the detection of underlying disorders of bone metabolism.</p>
</sec>
</div>
</front>
</TEI>
<affiliations><list></list>
<tree><noCountry><name sortKey="Agrawal, Prerna" sort="Agrawal, Prerna" uniqKey="Agrawal P" first="Prerna" last="Agrawal">Prerna Agrawal</name>
<name sortKey="Dave, Mahendra" sort="Dave, Mahendra" uniqKey="Dave M" first="Mahendra" last="Dave">Mahendra Dave</name>
<name sortKey="Dhariwal, Purvi" sort="Dhariwal, Purvi" uniqKey="Dhariwal P" first="Purvi" last="Dhariwal">Purvi Dhariwal</name>
<name sortKey="Pathak, Vandana" sort="Pathak, Vandana" uniqKey="Pathak V" first="Vandana" last="Pathak">Vandana Pathak</name>
<name sortKey="Saha, Mainak Kanti" sort="Saha, Mainak Kanti" uniqKey="Saha M" first="Mainak Kanti" last="Saha">Mainak Kanti Saha</name>
<name sortKey="Saha, Suparna Ganguly" sort="Saha, Suparna Ganguly" uniqKey="Saha S" first="Suparna Ganguly" last="Saha">Suparna Ganguly Saha</name>
<name sortKey="Saiprasad, Sakuru Venkata" sort="Saiprasad, Sakuru Venkata" uniqKey="Saiprasad S" first="Sakuru Venkata" last="Saiprasad">Sakuru Venkata Saiprasad</name>
<name sortKey="Vishwanathan, Vinod" sort="Vishwanathan, Vinod" uniqKey="Vishwanathan V" first="Vinod" last="Vishwanathan">Vinod Vishwanathan</name>
</noCountry>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000259 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000259 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= EdenteV2 |flux= Main |étape= Exploration |type= RBID |clé= PMC:5427438 |texte= Evaluation of Correlation between Salivary Calcium, Alkaline Phosphatase and Osteoporosis- A Prospective, Comparative and Observational Study }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:28511512" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a EdenteV2
![]() | This area was generated with Dilib version V0.6.32. | ![]() |