Tissue reactions to titanium implants containing bovine bone morphogenetic protein: a scanning electron microscopic investigation
Identifieur interne : 00AC37 ( Main/Curation ); précédent : 00AC36; suivant : 00AC38Tissue reactions to titanium implants containing bovine bone morphogenetic protein: a scanning electron microscopic investigation
Auteurs : WANG XIANG [République populaire de Chine] ; JIN YAN ; LIU BAOLIN ; ZHOU SHUIA ; YANG LIANJIA ; XI YANG ; F. H. WhiteSource :
- International journal of oral and maxillofacial surgery [ 0901-5027 ] ; 1994.
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- Pascal (Inist)
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- topic : Titane.
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Abstract
Cylindric titanium implants treated with bovine bone morphogenetic protein (bBMP) (Group I) and with bovine serum albumin (BSA) (Group II) were implanted in the edentulous mandibles of 15 adult dogs. They were examined 1, 2, 4, 8, and 12 weeks after insertion of the implants by scanning electron microscopy (SEM). In all specimens from Group I, active bone formation had occurred between the implant and host bone, with a well-adapted fit between the implant and the newly formed bone 4 weeks after implantation. The surrounding bone was of normal structure by week 8. However, 3 months after implantation, fibrous tissue was consistently seen surrounding parts of the implants in Group II. The results of this study suggest that the implants treated with bBMP are capable of forming new bone of normal structure at a faster rate than BSA controls and that this new bone is closely adapted to the implant surface
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Pascal:94-0371155Le document en format XML
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<author><name sortKey="Wang Xiang" sort="Wang Xiang" uniqKey="Wang Xiang" last="Wang Xiang">WANG XIANG</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Navy gen. hosp., dep. dentistry</s1>
<s2>Beijing</s2>
<s3>CHN</s3>
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<country>République populaire de Chine</country>
<placeName><settlement type="city">Pékin</settlement>
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<author><name sortKey="Jin Yan" sort="Jin Yan" uniqKey="Jin Yan" last="Jin Yan">JIN YAN</name>
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<author><name sortKey="Liu Baolin" sort="Liu Baolin" uniqKey="Liu Baolin" last="Liu Baolin">LIU BAOLIN</name>
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<author><name sortKey="Zhou Shuia" sort="Zhou Shuia" uniqKey="Zhou Shuia" last="Zhou Shuia">ZHOU SHUIA</name>
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<author><name sortKey="Yang Lianjia" sort="Yang Lianjia" uniqKey="Yang Lianjia" last="Yang Lianjia">YANG LIANJIA</name>
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<author><name sortKey="Xi Yang" sort="Xi Yang" uniqKey="Xi Yang" last="Xi Yang">XI YANG</name>
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<author><name sortKey="White, F H" sort="White, F H" uniqKey="White F" first="F. H." last="White">F. H. White</name>
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<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Navy gen. hosp., dep. dentistry</s1>
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<author><name sortKey="Jin Yan" sort="Jin Yan" uniqKey="Jin Yan" last="Jin Yan">JIN YAN</name>
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<author><name sortKey="Liu Baolin" sort="Liu Baolin" uniqKey="Liu Baolin" last="Liu Baolin">LIU BAOLIN</name>
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<author><name sortKey="Zhou Shuia" sort="Zhou Shuia" uniqKey="Zhou Shuia" last="Zhou Shuia">ZHOU SHUIA</name>
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<term>Dentistry</term>
<term>Dog</term>
<term>Edentulousness</term>
<term>Exploration</term>
<term>Implant</term>
<term>Osteointegration</term>
<term>Reaction</term>
<term>Scanning electron microscopy</term>
<term>Tissue</term>
<term>Titanium</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Ostéointégration</term>
<term>Implant</term>
<term>Titane</term>
<term>Edentation</term>
<term>Dentisterie</term>
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<term>Microscopie électronique balayage</term>
<term>Exploration</term>
<term>Tissu</term>
<term>Réaction</term>
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<front><div type="abstract" xml:lang="en">Cylindric titanium implants treated with bovine bone morphogenetic protein (bBMP) (Group I) and with bovine serum albumin (BSA) (Group II) were implanted in the edentulous mandibles of 15 adult dogs. They were examined 1, 2, 4, 8, and 12 weeks after insertion of the implants by scanning electron microscopy (SEM). In all specimens from Group I, active bone formation had occurred between the implant and host bone, with a well-adapted fit between the implant and the newly formed bone 4 weeks after implantation. The surrounding bone was of normal structure by week 8. However, 3 months after implantation, fibrous tissue was consistently seen surrounding parts of the implants in Group II. The results of this study suggest that the implants treated with bBMP are capable of forming new bone of normal structure at a faster rate than BSA controls and that this new bone is closely adapted to the implant surface</div>
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