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Gingival fine needle aspiration cytology in acute leukemia

Identifieur interne : 008492 ( Main/Curation ); précédent : 008491; suivant : 008493

Gingival fine needle aspiration cytology in acute leukemia

Auteurs : Bashar H. Abdullah [Iraq] ; Hassan I. Yahya ; Raja K. Kummoona ; Ferial A. Hilmi ; Khalid B. Mirza [Iraq]

Source :

RBID : ISTEX:22F442371B480A02602F4F280182ADDA20CA24E5

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English descriptors

Abstract

Background:  Oral findings in acute leukemia (AL) are common and could be the presenting feature of the disease, namely, gingival enlargement, ulceration, bleeding, and infection. Gingival enlargement in AL is either due to leukemic infiltration, or due to reactive hyperplasia. To differentiate between them a biopsy is required, but being highly contraindicated, biopsy has been substituted in this study by fine needle aspiration cytology (FNAC).

Url:
DOI: 10.1034/j.1600-0714.2002.310109.x

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ISTEX:22F442371B480A02602F4F280182ADDA20CA24E5

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Hassan I. Yahya
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Raja K. Kummoona
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</affiliation>
Ferial A. Hilmi
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<wicri:noCountry code="subField"></wicri:noCountry>
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Le document en format XML

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<keywords scheme="KwdEn" xml:lang="en">
<term>Acute</term>
<term>Acute Disease</term>
<term>Acute leukemia</term>
<term>Acute lymphoblastic leukemia</term>
<term>Acute myeloid leukemia</term>
<term>Acute myelomonocytic leukemia</term>
<term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Alveolar mucosa</term>
<term>Amll</term>
<term>Aspirate</term>
<term>Aspirated</term>
<term>Aspiration</term>
<term>Aspiration procedure</term>
<term>Biopsy, Needle (methods)</term>
<term>Blast cells stain</term>
<term>Case report</term>
<term>Case study</term>
<term>Clinical presentation</term>
<term>Cytology</term>
<term>Cytopathology</term>
<term>Dent assoc</term>
<term>Diagn cytopathol</term>
<term>Diagnosis</term>
<term>Different sites</term>
<term>Edentulous</term>
<term>Edentulous patient</term>
<term>Enlargement</term>
<term>Female</term>
<term>Fine needle aspiration biopsy</term>
<term>Fnac</term>
<term>Gingiva</term>
<term>Gingiva (pathology)</term>
<term>Gingival</term>
<term>Gingival Hemorrhage (pathology)</term>
<term>Gingival Hyperplasia (pathology)</term>
<term>Gingival enlargement</term>
<term>Gingival fnac</term>
<term>Gingival tissues</term>
<term>Humans</term>
<term>Hyperplasia</term>
<term>Interdental papilla</term>
<term>Leukemia</term>
<term>Leukemia (pathology)</term>
<term>Leukemia, Biphenotypic, Acute (pathology)</term>
<term>Leukemia, Monocytic, Acute (pathology)</term>
<term>Leukemia, Myeloid (pathology)</term>
<term>Leukemia, Myelomonocytic, Acute (pathology)</term>
<term>Leukemic</term>
<term>Leukemic Infiltration (pathology)</term>
<term>Leukemic enlargement</term>
<term>Leukemic gingival enlargement</term>
<term>Lineage leukemia</term>
<term>Lymphoid</term>
<term>Lymphoid leukemia</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Monocytic</term>
<term>Monocytic cells stain</term>
<term>Mouth Mucosa (pathology)</term>
<term>Mouth, Edentulous (pathology)</term>
<term>Myelomonocytic</term>
<term>Needle aspiration cytology</term>
<term>Negative pressure</term>
<term>Oral Ulcer (pathology)</term>
<term>Oral manifestations</term>
<term>Oral pathol</term>
<term>Papilla</term>
<term>Pathol</term>
<term>Pathology</term>
<term>Peripheral blood</term>
<term>Reactive</term>
<term>Reactive enlargement</term>
<term>Reactive hyperplasia</term>
<term>Subtypes</term>
<term>Tumorous infiltration</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Bouche édentée (anatomopathologie)</term>
<term>Femelle</term>
<term>Gencive (anatomopathologie)</term>
<term>Humains</term>
<term>Hyperplasie gingivale (anatomopathologie)</term>
<term>Hémorragie gingivale (anatomopathologie)</term>
<term>Infiltration leucémique (anatomopathologie)</term>
<term>Leucémie aigüe biphénotypique (anatomopathologie)</term>
<term>Leucémie aigüe monoblastique (anatomopathologie)</term>
<term>Leucémie aigüe myélomonocytaire (anatomopathologie)</term>
<term>Leucémie myéloïde (anatomopathologie)</term>
<term>Leucémies (anatomopathologie)</term>
<term>Maladie aigüe</term>
<term>Muqueuse de la bouche (anatomopathologie)</term>
<term>Mâle</term>
<term>Ponction-biopsie à l'aiguille ()</term>
<term>Sujet âgé</term>
<term>Ulcère buccal (anatomopathologie)</term>
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<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr">
<term>Bouche édentée</term>
<term>Gencive</term>
<term>Hyperplasie gingivale</term>
<term>Hémorragie gingivale</term>
<term>Infiltration leucémique</term>
<term>Leucémie aigüe biphénotypique</term>
<term>Leucémie aigüe monoblastique</term>
<term>Leucémie aigüe myélomonocytaire</term>
<term>Leucémie myéloïde</term>
<term>Leucémies</term>
<term>Muqueuse de la bouche</term>
<term>Ulcère buccal</term>
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<keywords scheme="MESH" qualifier="methods" xml:lang="en">
<term>Biopsy, Needle</term>
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<term>Gingiva</term>
<term>Gingival Hemorrhage</term>
<term>Gingival Hyperplasia</term>
<term>Leukemia</term>
<term>Leukemia, Biphenotypic, Acute</term>
<term>Leukemia, Monocytic, Acute</term>
<term>Leukemia, Myeloid</term>
<term>Leukemia, Myelomonocytic, Acute</term>
<term>Leukemic Infiltration</term>
<term>Mouth Mucosa</term>
<term>Mouth, Edentulous</term>
<term>Oral Ulcer</term>
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<term>Acute Disease</term>
<term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
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<term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Aigu</term>
<term>Anatomopathologie</term>
<term>Cytopathologie</term>
<term>Cytoponction</term>
<term>Diagnostic</term>
<term>Etude cas</term>
<term>Femelle</term>
<term>Gencive</term>
<term>Humains</term>
<term>Infiltration tumorale</term>
<term>Leucémie</term>
<term>Maladie aigüe</term>
<term>Mâle</term>
<term>Ponction-biopsie à l'aiguille</term>
<term>Sujet âgé</term>
</keywords>
<keywords scheme="Teeft" xml:lang="en">
<term>Acute leukemia</term>
<term>Acute lymphoblastic leukemia</term>
<term>Acute myeloid leukemia</term>
<term>Acute myelomonocytic leukemia</term>
<term>Alveolar mucosa</term>
<term>Amll</term>
<term>Aspirate</term>
<term>Aspirated</term>
<term>Aspiration</term>
<term>Aspiration procedure</term>
<term>Blast cells stain</term>
<term>Case report</term>
<term>Clinical presentation</term>
<term>Cytology</term>
<term>Dent assoc</term>
<term>Diagn cytopathol</term>
<term>Different sites</term>
<term>Edentulous</term>
<term>Edentulous patient</term>
<term>Enlargement</term>
<term>Fnac</term>
<term>Gingiva</term>
<term>Gingival</term>
<term>Gingival enlargement</term>
<term>Gingival fnac</term>
<term>Gingival tissues</term>
<term>Hyperplasia</term>
<term>Interdental papilla</term>
<term>Leukemia</term>
<term>Leukemic</term>
<term>Leukemic enlargement</term>
<term>Leukemic gingival enlargement</term>
<term>Lineage leukemia</term>
<term>Lymphoid</term>
<term>Lymphoid leukemia</term>
<term>Monocytic</term>
<term>Monocytic cells stain</term>
<term>Myelomonocytic</term>
<term>Needle aspiration cytology</term>
<term>Negative pressure</term>
<term>Oral manifestations</term>
<term>Oral pathol</term>
<term>Papilla</term>
<term>Pathol</term>
<term>Peripheral blood</term>
<term>Reactive</term>
<term>Reactive enlargement</term>
<term>Reactive hyperplasia</term>
<term>Subtypes</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr">
<term>Adulte</term>
<term>Cytologie</term>
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<div type="abstract">Background:  Oral findings in acute leukemia (AL) are common and could be the presenting feature of the disease, namely, gingival enlargement, ulceration, bleeding, and infection. Gingival enlargement in AL is either due to leukemic infiltration, or due to reactive hyperplasia. To differentiate between them a biopsy is required, but being highly contraindicated, biopsy has been substituted in this study by fine needle aspiration cytology (FNAC).</div>
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<s3>IRQ</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Iraq</country>
<wicri:noRegion>Department of Periodontology, College of Dentistry, University of Baghdad</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series>
<title level="j" type="main">Journal of oral pathology & medicine</title>
<title level="j" type="abbreviated">J. oral pathol. med.</title>
<idno type="ISSN">0904-2512</idno>
<imprint>
<date when="2002">2002</date>
</imprint>
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<title level="j" type="main">Journal of oral pathology & medicine</title>
<title level="j" type="abbreviated">J. oral pathol. med.</title>
<idno type="ISSN">0904-2512</idno>
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<term>Acute</term>
<term>Adult</term>
<term>Case study</term>
<term>Cytopathology</term>
<term>Diagnosis</term>
<term>Fine needle aspiration biopsy</term>
<term>Gingiva</term>
<term>Leukemia</term>
<term>Pathology</term>
<term>Tumorous infiltration</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr">
<term>Leucémie</term>
<term>Aigu</term>
<term>Infiltration tumorale</term>
<term>Gencive</term>
<term>Anatomopathologie</term>
<term>Cytopathologie</term>
<term>Cytoponction</term>
<term>Etude cas</term>
<term>Diagnostic</term>
<term>Adulte</term>
</keywords>
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<div type="abstract" xml:lang="en">Background: Oral findings in acute leukemia (AL) are common and could be the presenting feature of the disease, namely, gingival enlargement, ulceration, bleeding, and infection. Gingival enlargement in AL is either due to leukemic infiltration, or due to reactive hyperplasia. To differentiate between them a biopsy is required, but being highly contraindicated, biopsy has been substituted in this study by fine needle aspiration cytology (FNAC). Method: Gingival FNAC was performed on different sites in the upper and lower gingiva. Each site represents an interdental papilla, which was selected according to the clinical presentation, i.e., being enlarged or not. Seventy-two adult AL patients received a cytological and clinical examination in this study, and the cases were classified and categorized according to the French-American-British (FAB) criteria. Results: Twenty-one cases were diagnosed as being infiltrated, 16 with gingival enlargement, 4 with no evidence of enlargement. In one case the infiltration affected the alveolar mucosa of an edentulous patient. In six cases the ginigva was enlarged without being infiltrated (reactive hyperplasia). Leukemic gingival enlargement was seen mostly in patients with acute myeloid leukemia, particularly M4 and M5 subtypes; however, two patients with acute mixed lineage leukemia (AMLL) were both affected with leukemic infiltration. Conclusion: FNAC was shown to be a simple, non-traumatic and useful diagnostic procedure for screening leukemic infiltration in gingival tissues in AL patients.</div>
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<name sortKey="Abdullah, Bashar H" sort="Abdullah, Bashar H" uniqKey="Abdullah B" first="Bashar H." last="Abdullah">Bashar H. Abdullah</name>
</author>
<author>
<name sortKey="Yahya, Hassan I" sort="Yahya, Hassan I" uniqKey="Yahya H" first="Hassan I." last="Yahya">Hassan I. Yahya</name>
</author>
<author>
<name sortKey="Kummoona, Raja K" sort="Kummoona, Raja K" uniqKey="Kummoona R" first="Raja K." last="Kummoona">Raja K. Kummoona</name>
</author>
<author>
<name sortKey="Hilmi, Ferial A" sort="Hilmi, Ferial A" uniqKey="Hilmi F" first="Ferial A." last="Hilmi">Ferial A. Hilmi</name>
</author>
<author>
<name sortKey="Mirza, Khalid B" sort="Mirza, Khalid B" uniqKey="Mirza K" first="Khalid B." last="Mirza">Khalid B. Mirza</name>
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<name sortKey="Abdullah, Bashar H" sort="Abdullah, Bashar H" uniqKey="Abdullah B" first="Bashar H." last="Abdullah">Bashar H. Abdullah</name>
<affiliation></affiliation>
<affiliation wicri:level="1">
<country xml:lang="fr">Iraq</country>
<wicri:regionArea>Correspondence address: Bashar H. AbdullahP.O. Box 50912, Al'Maamoon, Baghdad</wicri:regionArea>
<wicri:noRegion>Baghdad</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Yahya, Hassan I" sort="Yahya, Hassan I" uniqKey="Yahya H" first="Hassan I." last="Yahya">Hassan I. Yahya</name>
<affiliation>
<wicri:noCountry code="subField">Medicine</wicri:noCountry>
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<name sortKey="Kummoona, Raja K" sort="Kummoona, Raja K" uniqKey="Kummoona R" first="Raja K." last="Kummoona">Raja K. Kummoona</name>
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<wicri:noCountry code="subField">Medicine</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Hilmi, Ferial A" sort="Hilmi, Ferial A" uniqKey="Hilmi F" first="Ferial A." last="Hilmi">Ferial A. Hilmi</name>
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<wicri:noCountry code="subField"></wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Mirza, Khalid B" sort="Mirza, Khalid B" uniqKey="Mirza K" first="Khalid B." last="Mirza">Khalid B. Mirza</name>
<affiliation wicri:level="1">
<country xml:lang="fr">Iraq</country>
<wicri:regionArea>Department of Periodontology, College of Dentistry, University of Baghdad</wicri:regionArea>
<wicri:noRegion>University of Baghdad</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series>
<title level="j" type="main">Journal of Oral Pathology & Medicine</title>
<title level="j" type="alt">JOURNAL ORAL PATHOLOGY MEDICINE</title>
<idno type="ISSN">0904-2512</idno>
<idno type="eISSN">1600-0714</idno>
<imprint>
<biblScope unit="vol">31</biblScope>
<biblScope unit="issue">1</biblScope>
<biblScope unit="page" from="55">55</biblScope>
<biblScope unit="page" to="58">58</biblScope>
<biblScope unit="page-count">4</biblScope>
<publisher>Blackwell Science, Ltd</publisher>
<pubPlace>Oxford, UK</pubPlace>
<date type="published" when="2002-01">2002-01</date>
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<idno type="ISSN">0904-2512</idno>
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<idno type="ISSN">0904-2512</idno>
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<keywords scheme="KwdEn" xml:lang="en">
<term>Acute leukemia</term>
<term>Acute lymphoblastic leukemia</term>
<term>Acute myeloid leukemia</term>
<term>Acute myelomonocytic leukemia</term>
<term>Alveolar mucosa</term>
<term>Amll</term>
<term>Aspirate</term>
<term>Aspirated</term>
<term>Aspiration</term>
<term>Aspiration procedure</term>
<term>Blast cells stain</term>
<term>Case report</term>
<term>Clinical presentation</term>
<term>Cytology</term>
<term>Dent assoc</term>
<term>Diagn cytopathol</term>
<term>Different sites</term>
<term>Edentulous</term>
<term>Edentulous patient</term>
<term>Enlargement</term>
<term>Fnac</term>
<term>Gingiva</term>
<term>Gingival</term>
<term>Gingival enlargement</term>
<term>Gingival fnac</term>
<term>Gingival tissues</term>
<term>Hyperplasia</term>
<term>Interdental papilla</term>
<term>Leukemia</term>
<term>Leukemic</term>
<term>Leukemic enlargement</term>
<term>Leukemic gingival enlargement</term>
<term>Lineage leukemia</term>
<term>Lymphoid</term>
<term>Lymphoid leukemia</term>
<term>Monocytic</term>
<term>Monocytic cells stain</term>
<term>Myelomonocytic</term>
<term>Needle aspiration cytology</term>
<term>Negative pressure</term>
<term>Oral manifestations</term>
<term>Oral pathol</term>
<term>Papilla</term>
<term>Pathol</term>
<term>Peripheral blood</term>
<term>Reactive</term>
<term>Reactive enlargement</term>
<term>Reactive hyperplasia</term>
<term>Subtypes</term>
</keywords>
<keywords scheme="Teeft" xml:lang="en">
<term>Acute leukemia</term>
<term>Acute lymphoblastic leukemia</term>
<term>Acute myeloid leukemia</term>
<term>Acute myelomonocytic leukemia</term>
<term>Alveolar mucosa</term>
<term>Amll</term>
<term>Aspirate</term>
<term>Aspirated</term>
<term>Aspiration</term>
<term>Aspiration procedure</term>
<term>Blast cells stain</term>
<term>Case report</term>
<term>Clinical presentation</term>
<term>Cytology</term>
<term>Dent assoc</term>
<term>Diagn cytopathol</term>
<term>Different sites</term>
<term>Edentulous</term>
<term>Edentulous patient</term>
<term>Enlargement</term>
<term>Fnac</term>
<term>Gingiva</term>
<term>Gingival</term>
<term>Gingival enlargement</term>
<term>Gingival fnac</term>
<term>Gingival tissues</term>
<term>Hyperplasia</term>
<term>Interdental papilla</term>
<term>Leukemia</term>
<term>Leukemic</term>
<term>Leukemic enlargement</term>
<term>Leukemic gingival enlargement</term>
<term>Lineage leukemia</term>
<term>Lymphoid</term>
<term>Lymphoid leukemia</term>
<term>Monocytic</term>
<term>Monocytic cells stain</term>
<term>Myelomonocytic</term>
<term>Needle aspiration cytology</term>
<term>Negative pressure</term>
<term>Oral manifestations</term>
<term>Oral pathol</term>
<term>Papilla</term>
<term>Pathol</term>
<term>Peripheral blood</term>
<term>Reactive</term>
<term>Reactive enlargement</term>
<term>Reactive hyperplasia</term>
<term>Subtypes</term>
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<div type="abstract">Background:  Oral findings in acute leukemia (AL) are common and could be the presenting feature of the disease, namely, gingival enlargement, ulceration, bleeding, and infection. Gingival enlargement in AL is either due to leukemic infiltration, or due to reactive hyperplasia. To differentiate between them a biopsy is required, but being highly contraindicated, biopsy has been substituted in this study by fine needle aspiration cytology (FNAC).</div>
</front>
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<affiliation wicri:level="1">
<nlm:affiliation>Department of Oral Diagnosis, College of Dentistry, University of Baghdad, Iraq.</nlm:affiliation>
<country xml:lang="fr">Iraq</country>
<wicri:regionArea>Department of Oral Diagnosis, College of Dentistry, University of Baghdad</wicri:regionArea>
<wicri:noRegion>University of Baghdad</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Yahya, Hassan I" sort="Yahya, Hassan I" uniqKey="Yahya H" first="Hassan I" last="Yahya">Hassan I. Yahya</name>
</author>
<author>
<name sortKey="Kummoona, Raja K" sort="Kummoona, Raja K" uniqKey="Kummoona R" first="Raja K" last="Kummoona">Raja K. Kummoona</name>
</author>
<author>
<name sortKey="Hilmi, Ferial A" sort="Hilmi, Ferial A" uniqKey="Hilmi F" first="Ferial A" last="Hilmi">Ferial A. Hilmi</name>
</author>
<author>
<name sortKey="Mirza, Khalid B" sort="Mirza, Khalid B" uniqKey="Mirza K" first="Khalid B" last="Mirza">Khalid B. Mirza</name>
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<nlm:affiliation>Department of Oral Diagnosis, College of Dentistry, University of Baghdad, Iraq.</nlm:affiliation>
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<wicri:regionArea>Department of Oral Diagnosis, College of Dentistry, University of Baghdad</wicri:regionArea>
<wicri:noRegion>University of Baghdad</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Yahya, Hassan I" sort="Yahya, Hassan I" uniqKey="Yahya H" first="Hassan I" last="Yahya">Hassan I. Yahya</name>
</author>
<author>
<name sortKey="Kummoona, Raja K" sort="Kummoona, Raja K" uniqKey="Kummoona R" first="Raja K" last="Kummoona">Raja K. Kummoona</name>
</author>
<author>
<name sortKey="Hilmi, Ferial A" sort="Hilmi, Ferial A" uniqKey="Hilmi F" first="Ferial A" last="Hilmi">Ferial A. Hilmi</name>
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<term>Acute Disease</term>
<term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Biopsy, Needle (methods)</term>
<term>Female</term>
<term>Gingiva (pathology)</term>
<term>Gingival Hemorrhage (pathology)</term>
<term>Gingival Hyperplasia (pathology)</term>
<term>Humans</term>
<term>Leukemia (pathology)</term>
<term>Leukemia, Biphenotypic, Acute (pathology)</term>
<term>Leukemia, Monocytic, Acute (pathology)</term>
<term>Leukemia, Myeloid (pathology)</term>
<term>Leukemia, Myelomonocytic, Acute (pathology)</term>
<term>Leukemic Infiltration (pathology)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Mouth Mucosa (pathology)</term>
<term>Mouth, Edentulous (pathology)</term>
<term>Oral Ulcer (pathology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Bouche édentée (anatomopathologie)</term>
<term>Femelle</term>
<term>Gencive (anatomopathologie)</term>
<term>Humains</term>
<term>Hyperplasie gingivale (anatomopathologie)</term>
<term>Hémorragie gingivale (anatomopathologie)</term>
<term>Infiltration leucémique (anatomopathologie)</term>
<term>Leucémie aigüe biphénotypique (anatomopathologie)</term>
<term>Leucémie aigüe monoblastique (anatomopathologie)</term>
<term>Leucémie aigüe myélomonocytaire (anatomopathologie)</term>
<term>Leucémie myéloïde (anatomopathologie)</term>
<term>Leucémies (anatomopathologie)</term>
<term>Maladie aigüe</term>
<term>Muqueuse de la bouche (anatomopathologie)</term>
<term>Mâle</term>
<term>Ponction-biopsie à l'aiguille ()</term>
<term>Sujet âgé</term>
<term>Ulcère buccal (anatomopathologie)</term>
</keywords>
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<term>Bouche édentée</term>
<term>Gencive</term>
<term>Hyperplasie gingivale</term>
<term>Hémorragie gingivale</term>
<term>Infiltration leucémique</term>
<term>Leucémie aigüe biphénotypique</term>
<term>Leucémie aigüe monoblastique</term>
<term>Leucémie aigüe myélomonocytaire</term>
<term>Leucémie myéloïde</term>
<term>Leucémies</term>
<term>Muqueuse de la bouche</term>
<term>Ulcère buccal</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en">
<term>Biopsy, Needle</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en">
<term>Gingiva</term>
<term>Gingival Hemorrhage</term>
<term>Gingival Hyperplasia</term>
<term>Leukemia</term>
<term>Leukemia, Biphenotypic, Acute</term>
<term>Leukemia, Monocytic, Acute</term>
<term>Leukemia, Myeloid</term>
<term>Leukemia, Myelomonocytic, Acute</term>
<term>Leukemic Infiltration</term>
<term>Mouth Mucosa</term>
<term>Mouth, Edentulous</term>
<term>Oral Ulcer</term>
</keywords>
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<term>Acute Disease</term>
<term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
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<term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Femelle</term>
<term>Humains</term>
<term>Maladie aigüe</term>
<term>Mâle</term>
<term>Ponction-biopsie à l'aiguille</term>
<term>Sujet âgé</term>
</keywords>
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<div type="abstract" xml:lang="en">Oral findings in acute leukemia (AL) are common and could be the presenting feature of the disease, namely, gingival enlargement, ulceration, bleeding, and infection. Gingival enlargement in AL is either due to leukemic infiltration, or due to reactive hyperplasia. To differentiate between them a biopsy is required, but being highly contraindicated, biopsy has been substituted in this study by fine needle aspiration cytology (FNAC).</div>
</front>
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