Large-scale Clinical Endodontic Research in The National Dental Practice-Based Research Network: Study Overview and Methods
Identifieur interne : 003189 ( Main/Curation ); précédent : 003188; suivant : 003190Large-scale Clinical Endodontic Research in The National Dental Practice-Based Research Network: Study Overview and Methods
Auteurs : Donald R. Nixdorf [États-Unis] ; Alan S. Law [États-Unis] ; John O. Look [États-Unis] ; D. Brad Rindal [États-Unis] ; Emily U. Durand [États-Unis] ; Wenjun Kang [États-Unis] ; Bonita S. Agee [États-Unis] ; Jeffrey L. Fellows [États-Unis] ; Valeria V. Gordan [États-Unis] ; Gregg H. Gilbert [États-Unis]Source :
- Journal of endodontics [ 0099-2399 ] ; 2012.
Abstract
This paper reports on the feasibility of conducting a large-scale endodontic prospective cohort study in The National Dental Practice-Based Research Network. This study was designed to measure pain and burden associated with initial orthograde root canal therapy (RCT) and to explore potential prognostic factors for pain outcomes. The main objectives of this first report in a series are to describe the project’s feasibility and methods and the demographics of the sample obtained.
Sixty-two dentist practitioner-investigators (46 generalists, 16 endodontists) in five geographical areas were certified within the network and trained regarding the standardized study protocol. Enrollment and baseline data collection occurred over 6 months, with post-obturation follow-up for another 6 months. Patients and dentists completed questionnaires before and immediately after treatment visits. Patients also completed questionnaires at 1 week, 3 months, and 6 months after obturation.
Enrollment exceeded target expectations, with 708 eligible patient-participants. Questionnaire return rates were good, ranging between 90% to 100%. Patient demographics were typical of persons who receive RCT in the United States: mean age 48 years (SD 13 years), with most being female (59%), college-educated (81%), white non-Hispanic (86%), and having dental insurance (81%). The tooth types being treated were also typical: 61% molars, 28% premolars, and 11% anteriors, with maxillary teeth being predominant (59%).
This study demonstrates the feasibility of conducting large-scale endodontic prospective cohort studies in the network. Patients were rapidly recruited, with high levels of compliance in data collection.
Url:
DOI: 10.1016/j.joen.2012.08.002
PubMed: 23063220
PubMed Central: 3652657
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Research Network: Study Overview and Methods</title><author><name sortKey="Nixdorf, Donald R" sort="Nixdorf, Donald R" uniqKey="Nixdorf D" first="Donald R." last="Nixdorf">Donald R. Nixdorf</name><affiliation wicri:level="2"><nlm:aff id="A1">Division of TMD & Orofacial Pain, School of Dentistry, University of Minnesota, Minneapolis, MN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Division of TMD & Orofacial Pain, School of Dentistry, University of Minnesota, Minneapolis</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A2">Department of Neurology, Medical School, University of Minnesota, Minneapolis, MN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Department of Neurology, Medical School, University of Minnesota, Minneapolis</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A3">HealthPartners Institute for Education and Research, Bloomington, MN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>HealthPartners Institute for Education and Research, Bloomington</wicri:cityArea></affiliation></author><author><name sortKey="Law, Alan S" sort="Law, Alan S" uniqKey="Law A" first="Alan S." last="Law">Alan S. Law</name><affiliation wicri:level="2"><nlm:aff id="A4">Private Practice, The Dental Specialists, Lake Elmo, MN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Private Practice, The Dental Specialists, Lake Elmo</wicri:cityArea></affiliation></author><author><name sortKey="Look, John O" sort="Look, John O" uniqKey="Look J" first="John O." last="Look">John O. Look</name><affiliation wicri:level="2"><nlm:aff id="A1">Division of TMD & Orofacial Pain, School of Dentistry, University of Minnesota, Minneapolis, MN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Division of TMD & Orofacial Pain, School of Dentistry, University of Minnesota, Minneapolis</wicri:cityArea></affiliation></author><author><name sortKey="Rindal, D Brad" sort="Rindal, D Brad" uniqKey="Rindal D" first="D. Brad" last="Rindal">D. Brad Rindal</name><affiliation wicri:level="2"><nlm:aff id="A3">HealthPartners Institute for Education and Research, Bloomington, MN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>HealthPartners Institute for Education and Research, Bloomington</wicri:cityArea></affiliation></author><author><name sortKey="Durand, Emily U" sort="Durand, Emily U" uniqKey="Durand E" first="Emily U." last="Durand">Emily U. Durand</name><affiliation wicri:level="2"><nlm:aff id="A3">HealthPartners Institute for Education and Research, Bloomington, MN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>HealthPartners Institute for Education and Research, Bloomington</wicri:cityArea></affiliation></author><author><name sortKey="Kang, Wenjun" sort="Kang, Wenjun" uniqKey="Kang W" first="Wenjun" last="Kang">Wenjun Kang</name><affiliation wicri:level="2"><nlm:aff id="A1">Division of TMD & Orofacial Pain, School of Dentistry, University of Minnesota, Minneapolis, MN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Division of TMD & Orofacial Pain, School of Dentistry, University of Minnesota, Minneapolis</wicri:cityArea></affiliation></author><author><name sortKey="Agee, Bonita S" sort="Agee, Bonita S" uniqKey="Agee B" first="Bonita S." last="Agee">Bonita S. Agee</name><affiliation wicri:level="2"><nlm:aff id="A5">Division of Preventive Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea>Division of Preventive Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation></author><author><name sortKey="Fellows, Jeffrey L" sort="Fellows, Jeffrey L" uniqKey="Fellows J" first="Jeffrey L." last="Fellows">Jeffrey L. Fellows</name><affiliation wicri:level="2"><nlm:aff id="A6">Kaiser Permanente Center for Health Research, Portland, OR</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Oregon</region></placeName><wicri:cityArea>Kaiser Permanente Center for Health Research, Portland</wicri:cityArea></affiliation></author><author><name sortKey="Gordan, Valeria V" sort="Gordan, Valeria V" uniqKey="Gordan V" first="Valeria V." last="Gordan">Valeria V. Gordan</name><affiliation wicri:level="2"><nlm:aff id="A7">Department of Restorative Dental Sciences, College of Dentistry, University of Florida, Gainesville, FL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Floride</region></placeName><wicri:cityArea>Department of Restorative Dental Sciences, College of Dentistry, University of Florida, Gainesville</wicri:cityArea></affiliation></author><author><name sortKey="Gilbert, Gregg H" sort="Gilbert, Gregg H" uniqKey="Gilbert G" first="Gregg H." last="Gilbert">Gregg H. Gilbert</name><affiliation wicri:level="2"><nlm:aff id="A8">Department of Clinical and Community Sciences, School of Dentistry, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea>Department of Clinical and Community Sciences, School of Dentistry, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation></author></analytic><series><title level="j">Journal of endodontics</title><idno type="ISSN">0099-2399</idno><idno type="eISSN">1878-3554</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="S1"><title>Introduction</title><p id="P1">This paper reports on the feasibility of conducting a large-scale endodontic prospective
cohort study in The National Dental Practice-Based Research Network. This study was designed to
measure pain and burden associated with initial orthograde root canal therapy (RCT) and to explore
potential prognostic factors for pain outcomes. The main objectives of this first report in a series
are to describe the project’s feasibility and methods and the demographics of the sample
obtained.</p></sec><sec id="S2"><title>Methods</title><p id="P2">Sixty-two dentist practitioner-investigators (46 generalists, 16 endodontists) in five
geographical areas were certified within the network and trained regarding the standardized study
protocol. Enrollment and baseline data collection occurred over 6 months, with post-obturation
follow-up for another 6 months. Patients and dentists completed questionnaires before and
immediately after treatment visits. Patients also completed questionnaires at 1 week, 3 months, and
6 months after obturation.</p></sec><sec id="S3"><title>Results</title><p id="P3">Enrollment exceeded target expectations, with 708 eligible patient-participants.
Questionnaire return rates were good, ranging between 90% to 100%. Patient demographics were typical
of persons who receive RCT in the United States: mean age 48 years (SD 13 years), with most being
female (59%), college-educated (81%), white non-Hispanic (86%), and having dental insurance (81%).
The tooth types being treated were also typical: 61% molars, 28% premolars, and 11% anteriors, with
maxillary teeth being predominant (59%).</p></sec><sec id="S4"><title>Conclusions</title><p id="P4">This study demonstrates the feasibility of conducting large-scale endodontic prospective
cohort studies in the network. Patients were rapidly recruited, with high levels of compliance in
data collection.</p></sec></div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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