Rhinocerebral Mucormycosis: Report of a Rare Case
Identifieur interne : 000082 ( Main/Curation ); précédent : 000081; suivant : 000083Rhinocerebral Mucormycosis: Report of a Rare Case
Auteurs : Richa Sahota ; Ramandeep Gambhir ; Samir Anand ; Avani DixitSource :
- Ethiopian Journal of Health Sciences [ 1029-1857 ] ; 2017.
Abstract
Mucormycosis is one of the rapidly progressing and lethal form of fungal infection which involves the nose and paranasal sinuses of the head and the neck regions. Mucormycosis also remains a threat to patients with uncontrolled diabetes or other predisposing systemic conditions. It manifests as rhinocerebral, pulmonary, gastrointestinal, cutaneous or disseminated form. The underlying conditions can influence clinical presentation and often delay diagnosis, with resultant poor outcomes.
We report a case of rhinocerebral mucormycosis in a 75 year-old diabetic patient with emphasise on diagnosis, treatment and survival options of patient from this potentially fatal fungal infection. Extra oral examination revealed mild non-tender swelling on the face, unable to see from left eye, impaired sense of smell, difficulty in speech and nasal stuffiness. Intra-oral examination showed necrosis of mucosa and underlying bone in relation to canine to the tuberosity area of the left vestibular region of the maxilla.
Timely diagnosis is critical to survival and minimization of morbidity. Institution of surgical and medical therapy is critical in maximizing the likelihood of good outcome.
Url:
PubMed: 28458494
PubMed Central: 5390232
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Richa Sahota<affiliation><nlm:aff id="A1">Department of Oral Pathology, Rayat and Bahra Dental College and Hospital, Mohali</nlm:aff>
<wicri:noCountry code="subfield">Mohali</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="A2">Department of Public Health Dentistry, Gian Sagar Dental College and Hospital, Rajpura</nlm:aff>
<wicri:noCountry code="subfield">Rajpura</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="A3">Department of Periodontology, Rayat and Bahra Dental College and Hospital, Mohali</nlm:aff>
<wicri:noCountry code="subfield">Mohali</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="A4">Department of Oral Medicine and Radiology, Swami Devi Dyal Dental College and Hospital, Golpura, Panchkula</nlm:aff>
<wicri:noCountry code="subfield">Panchkula</wicri:noCountry>
</affiliation>
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<series><title level="j">Ethiopian Journal of Health Sciences</title>
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<front><div type="abstract" xml:lang="en"><sec><title>Background</title>
<p>Mucormycosis is one of the rapidly progressing and lethal form of fungal infection which involves the nose and paranasal sinuses of the head and the neck regions. Mucormycosis also remains a threat to patients with uncontrolled diabetes or other predisposing systemic conditions. It manifests as rhinocerebral, pulmonary, gastrointestinal, cutaneous or disseminated form. The underlying conditions can influence clinical presentation and often delay diagnosis, with resultant poor outcomes.</p>
</sec>
<sec sec-type="cases"><title>Case Details</title>
<p>We report a case of rhinocerebral mucormycosis in a 75 year-old diabetic patient with emphasise on diagnosis, treatment and survival options of patient from this potentially fatal fungal infection. Extra oral examination revealed mild non-tender swelling on the face, unable to see from left eye, impaired sense of smell, difficulty in speech and nasal stuffiness. Intra-oral examination showed necrosis of mucosa and underlying bone in relation to canine to the tuberosity area of the left vestibular region of the maxilla.</p>
</sec>
<sec sec-type="conclusions"><title>Conclusion</title>
<p>Timely diagnosis is critical to survival and minimization of morbidity. Institution of surgical and medical therapy is critical in maximizing the likelihood of good outcome.</p>
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