Scurvy and vitamin C deficiency in Crohn's disease.
Identifieur interne : 006A24 ( Istex/Curation ); précédent : 006A23; suivant : 006A25Scurvy and vitamin C deficiency in Crohn's disease.
Auteurs : B. D. LinakerSource :
- Postgraduate Medical Journal [ 0032-5473 ] ; 1979-01.
Descripteurs français
- Wicri :
- topic : Vitamine.
English descriptors
- KwdEn :
- Ascorbic, Ascorbic acid, Bowel, Churchill livingstone, Clinical evidence, Clinical science, Colonic involvement, Daily intake, Dietary intake, Fistula formation, Folic acid, Gastroenterology, Human ileum, Intestine, Kingdom standards, Leucocyte, Leucocyte ascorbic acid, Leucocyte ascorbic acid levels, Malabsorption, Normal range, Oral intake, Oral lesions, Pharmacological basis, Present patient, Saunders, Scurvy, Significant difference, Small intestine, Vitamin, White blood cells.
- Teeft :
- Ascorbic, Ascorbic acid, Bowel, Churchill livingstone, Clinical evidence, Clinical science, Colonic involvement, Daily intake, Dietary intake, Fistula formation, Folic acid, Gastroenterology, Human ileum, Intestine, Kingdom standards, Leucocyte, Leucocyte ascorbic acid, Leucocyte ascorbic acid levels, Malabsorption, Normal range, Oral intake, Oral lesions, Pharmacological basis, Present patient, Saunders, Scurvy, Significant difference, Small intestine, Vitamin, White blood cells.
Abstract
A case of scurvy presenting in a patient with Crohn's disease is reported. A normal response to replacement therapy is seen. Vitamin C (ascorbic acid) deficiency was found in 7 out of 10 patients with clinically quiescent Crohn's disease, 4 of whom had an adequate oral intake of vitamin C. There was no significant difference in oral intake between patients with Crohn's disease and matched controls but there was a significant difference (P less than 0.001) in leucocyte ascorbic acid levels. It is recommended that patients with Crohn's disease be screened for vitamin C deficiency and receive prophylactic vitamin C supplements daily.
Url:
DOI: 10.1136/pgmj.55.639.26
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ISTEX:D5D8E10AE8E8D2A7EED778F1DFD5F45A3340C058Le document en format XML
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<series><title level="j">Postgraduate Medical Journal</title>
<title level="j" type="abbrev">Postgrad Med J</title>
<idno type="ISSN">0032-5473</idno>
<idno type="eISSN">1469-0756</idno>
<imprint><publisher>The Fellowship of Postgraduate Medicine</publisher>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Ascorbic</term>
<term>Ascorbic acid</term>
<term>Bowel</term>
<term>Churchill livingstone</term>
<term>Clinical evidence</term>
<term>Clinical science</term>
<term>Colonic involvement</term>
<term>Daily intake</term>
<term>Dietary intake</term>
<term>Fistula formation</term>
<term>Folic acid</term>
<term>Gastroenterology</term>
<term>Human ileum</term>
<term>Intestine</term>
<term>Kingdom standards</term>
<term>Leucocyte</term>
<term>Leucocyte ascorbic acid</term>
<term>Leucocyte ascorbic acid levels</term>
<term>Malabsorption</term>
<term>Normal range</term>
<term>Oral intake</term>
<term>Oral lesions</term>
<term>Pharmacological basis</term>
<term>Present patient</term>
<term>Saunders</term>
<term>Scurvy</term>
<term>Significant difference</term>
<term>Small intestine</term>
<term>Vitamin</term>
<term>White blood cells</term>
</keywords>
<keywords scheme="Teeft" xml:lang="en"><term>Ascorbic</term>
<term>Ascorbic acid</term>
<term>Bowel</term>
<term>Churchill livingstone</term>
<term>Clinical evidence</term>
<term>Clinical science</term>
<term>Colonic involvement</term>
<term>Daily intake</term>
<term>Dietary intake</term>
<term>Fistula formation</term>
<term>Folic acid</term>
<term>Gastroenterology</term>
<term>Human ileum</term>
<term>Intestine</term>
<term>Kingdom standards</term>
<term>Leucocyte</term>
<term>Leucocyte ascorbic acid</term>
<term>Leucocyte ascorbic acid levels</term>
<term>Malabsorption</term>
<term>Normal range</term>
<term>Oral intake</term>
<term>Oral lesions</term>
<term>Pharmacological basis</term>
<term>Present patient</term>
<term>Saunders</term>
<term>Scurvy</term>
<term>Significant difference</term>
<term>Small intestine</term>
<term>Vitamin</term>
<term>White blood cells</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Vitamine</term>
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<front><div type="abstract" xml:lang="en">A case of scurvy presenting in a patient with Crohn's disease is reported. A normal response to replacement therapy is seen. Vitamin C (ascorbic acid) deficiency was found in 7 out of 10 patients with clinically quiescent Crohn's disease, 4 of whom had an adequate oral intake of vitamin C. There was no significant difference in oral intake between patients with Crohn's disease and matched controls but there was a significant difference (P less than 0.001) in leucocyte ascorbic acid levels. It is recommended that patients with Crohn's disease be screened for vitamin C deficiency and receive prophylactic vitamin C supplements daily.</div>
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