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Osteoradionecrosis of the mandible: Study of 104 cases treated by hemimandibulectomy

Identifieur interne : 002702 ( Istex/Curation ); précédent : 002701; suivant : 002703

Osteoradionecrosis of the mandible: Study of 104 cases treated by hemimandibulectomy

Auteurs : V. N. Koka [France] ; R. Deo [France] ; A. Lusinchi [France] ; J. Roland [France] ; G. Schwaab [France]

Source :

RBID : ISTEX:4F29FCABA8A9F12F37CB1906CCF92BD4B24A3106

Abstract

One hundred and four cases of osteoradionecrosis (ORN) of the mandible following irradiation of head and neck cancer are reported. Conservative management for ORN failed in all cases. Indications of hemimandibulectomy included intractable pain, severe trismus, pathological fracture, oro-cutaneous fistula and persistent exposure of bone. Surgical approach was intra-oral in 100 cases and extra-oral in four. Immediate soft tissue reconstructions were carried out in 20 per cent cases. Post-operative complications included minor sepsis (8.6 per cent), major sepsis (2.9 per cent), haemorrhage (2.9 per cent) and fistula (3.8 per cent). Major complications occurred only in patients treated exclusively by external irradiation at doses equal to or higher than 65 Gy. Relief from pain and trismus was obtained and normal swallowing was established following radical surgery.

Url:
DOI: 10.1017/S0022215100112551

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ISTEX:4F29FCABA8A9F12F37CB1906CCF92BD4B24A3106

Le document en format XML

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<div type="abstract">One hundred and four cases of osteoradionecrosis (ORN) of the mandible following irradiation of head and neck cancer are reported. Conservative management for ORN failed in all cases. Indications of hemimandibulectomy included intractable pain, severe trismus, pathological fracture, oro-cutaneous fistula and persistent exposure of bone. Surgical approach was intra-oral in 100 cases and extra-oral in four. Immediate soft tissue reconstructions were carried out in 20 per cent cases. Post-operative complications included minor sepsis (8.6 per cent), major sepsis (2.9 per cent), haemorrhage (2.9 per cent) and fistula (3.8 per cent). Major complications occurred only in patients treated exclusively by external irradiation at doses equal to or higher than 65 Gy. Relief from pain and trismus was obtained and normal swallowing was established following radical surgery.</div>
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