Clinical evaluation of demineralized bone allograft in a hyaluronic acid carrier for sinus lift augmentation in humans: a computed tomography and histomorphometric study
Identifieur interne : 007E40 ( Istex/Corpus ); précédent : 007E39; suivant : 007E41Clinical evaluation of demineralized bone allograft in a hyaluronic acid carrier for sinus lift augmentation in humans: a computed tomography and histomorphometric study
Auteurs : Zvi Schwartz ; Moshe Goldstein ; Einav Raviv ; Ariel Hirsch ; Don M. Ranly ; Barbara D. BoyanSource :
- Clinical Oral Implants Research [ 0905-7161 ] ; 2007-04.
English descriptors
- KwdEn :
- Absolute amount, Allograft, Alveolar height, Alveolar ridge height, Augmentation, Augmentation procedure, Autogenous, Autogenous bone, Biopsy, Bone allograft, Bone formation, Bone graft material, Bone graft materials, Bone graft substitute, Bone graft substitutes, Bone volume, Buccal window, Clin, Clinical effectiveness, Clinical evaluation, Clinical study, Closure, Collagen membrane, Complete wound closure, Consent forms, Considerable bone marrow, Considerable variation, Cortical bone, Demineralized, Demineralized bone allograft, Dental medicine, Deproteinized cancellous, Dfdba, Dfdba particles, Elevation, Graft, Graft material, Graft particles, Grafted sites, Granule, Histologic, Histologic sections, Histomorphometric study, Hyaluronic, Hyaluronic acid, Hyaluronic acid carrier, Impl, Implant, Implant placement, Implants research, International journal, Local anesthesia, Maxillary, Maxillary sinus, Maxillofacial surgery, Mineralized bone graft substitute, Morphometric analysis, Musculoskeletal transplant foundation, Oral impl, Oral maxillofacial implants, Osteogenic properties, Other materials, Passive closure, Phosphate granules, Preoperative ridge height, Residual graft material, Restorative dentistry, Results show, Ridge height, Ridge heights, Similar extent, Sinus, Sinus elevation, Small amount, Support bone formation, Surgical site, Tissue dimensions, Torque values, Treatment group, Treatment groups, Valentini abensur, Welcome addition.
- Teeft :
- Absolute amount, Allograft, Alveolar height, Alveolar ridge height, Augmentation, Augmentation procedure, Autogenous, Autogenous bone, Biopsy, Bone allograft, Bone formation, Bone graft material, Bone graft materials, Bone graft substitute, Bone graft substitutes, Bone volume, Buccal window, Clin, Clinical effectiveness, Clinical evaluation, Clinical study, Closure, Collagen membrane, Complete wound closure, Consent forms, Considerable bone marrow, Considerable variation, Cortical bone, Demineralized, Demineralized bone allograft, Dental medicine, Deproteinized cancellous, Dfdba, Dfdba particles, Elevation, Graft, Graft material, Graft particles, Grafted sites, Granule, Histologic, Histologic sections, Histomorphometric study, Hyaluronic, Hyaluronic acid, Hyaluronic acid carrier, Impl, Implant, Implant placement, Implants research, International journal, Local anesthesia, Maxillary, Maxillary sinus, Maxillofacial surgery, Mineralized bone graft substitute, Morphometric analysis, Musculoskeletal transplant foundation, Oral impl, Oral maxillofacial implants, Osteogenic properties, Other materials, Passive closure, Phosphate granules, Preoperative ridge height, Residual graft material, Restorative dentistry, Results show, Ridge height, Ridge heights, Similar extent, Sinus, Sinus elevation, Small amount, Support bone formation, Surgical site, Tissue dimensions, Torque values, Treatment group, Treatment groups, Valentini abensur, Welcome addition.
Abstract
Objectives: Natural and synthetic graft materials are used routinely in sinus floor augmentations to help support implants in atrophic maxillary ridges. This clinical study was based on the hypothesis that the clinical effectiveness of demineralized freeze‐dried bone allograft/demineralized bone matrix (DFDBA/DBM) in sinus lifts varies when used in combination bone graft substitute materials. To test this hypothesis, DFDBA was used together with one of three materials: in saline plus anorganic bone (DFDBA: Bio‐Oss®); in hyaluronic acid (DFDBA: HY, 32 : 68, w/w; DBX®) alone; DBX® plus Bio‐Oss®; and DBX® plus tricalcium phosphate granules (β‐TCP).
Url:
DOI: 10.1111/j.1600-0501.2006.01303.x
Links to Exploration step
ISTEX:FF9692D9FDA0790A697788B46C8279C31BF4D789Le document en format XML
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Boyan</name><affiliation><mods:affiliation>Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Clinical Oral Implants Research</title><title level="j" type="alt">CLINICAL ORAL IMPLANTS RESEARCH</title><idno type="ISSN">0905-7161</idno><idno type="eISSN">1600-0501</idno><imprint><biblScope unit="vol">18</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="204">204</biblScope><biblScope unit="page" to="211">211</biblScope><biblScope unit="page-count">8</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2007-04">2007-04</date></imprint><idno type="ISSN">0905-7161</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0905-7161</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Absolute amount</term><term>Allograft</term><term>Alveolar height</term><term>Alveolar ridge height</term><term>Augmentation</term><term>Augmentation procedure</term><term>Autogenous</term><term>Autogenous bone</term><term>Biopsy</term><term>Bone allograft</term><term>Bone formation</term><term>Bone graft material</term><term>Bone graft materials</term><term>Bone graft substitute</term><term>Bone graft substitutes</term><term>Bone volume</term><term>Buccal window</term><term>Clin</term><term>Clinical effectiveness</term><term>Clinical evaluation</term><term>Clinical study</term><term>Closure</term><term>Collagen membrane</term><term>Complete wound closure</term><term>Consent forms</term><term>Considerable bone marrow</term><term>Considerable variation</term><term>Cortical bone</term><term>Demineralized</term><term>Demineralized bone allograft</term><term>Dental medicine</term><term>Deproteinized cancellous</term><term>Dfdba</term><term>Dfdba particles</term><term>Elevation</term><term>Graft</term><term>Graft material</term><term>Graft particles</term><term>Grafted sites</term><term>Granule</term><term>Histologic</term><term>Histologic sections</term><term>Histomorphometric study</term><term>Hyaluronic</term><term>Hyaluronic acid</term><term>Hyaluronic acid carrier</term><term>Impl</term><term>Implant</term><term>Implant placement</term><term>Implants research</term><term>International journal</term><term>Local anesthesia</term><term>Maxillary</term><term>Maxillary sinus</term><term>Maxillofacial surgery</term><term>Mineralized bone graft substitute</term><term>Morphometric analysis</term><term>Musculoskeletal transplant foundation</term><term>Oral impl</term><term>Oral maxillofacial implants</term><term>Osteogenic properties</term><term>Other materials</term><term>Passive closure</term><term>Phosphate granules</term><term>Preoperative ridge height</term><term>Residual graft material</term><term>Restorative dentistry</term><term>Results show</term><term>Ridge height</term><term>Ridge heights</term><term>Similar extent</term><term>Sinus</term><term>Sinus elevation</term><term>Small amount</term><term>Support bone formation</term><term>Surgical site</term><term>Tissue dimensions</term><term>Torque values</term><term>Treatment group</term><term>Treatment groups</term><term>Valentini abensur</term><term>Welcome addition</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Absolute amount</term><term>Allograft</term><term>Alveolar height</term><term>Alveolar ridge height</term><term>Augmentation</term><term>Augmentation procedure</term><term>Autogenous</term><term>Autogenous bone</term><term>Biopsy</term><term>Bone allograft</term><term>Bone formation</term><term>Bone graft material</term><term>Bone graft materials</term><term>Bone graft substitute</term><term>Bone graft substitutes</term><term>Bone volume</term><term>Buccal window</term><term>Clin</term><term>Clinical effectiveness</term><term>Clinical evaluation</term><term>Clinical study</term><term>Closure</term><term>Collagen membrane</term><term>Complete wound closure</term><term>Consent forms</term><term>Considerable bone marrow</term><term>Considerable variation</term><term>Cortical bone</term><term>Demineralized</term><term>Demineralized bone allograft</term><term>Dental medicine</term><term>Deproteinized cancellous</term><term>Dfdba</term><term>Dfdba particles</term><term>Elevation</term><term>Graft</term><term>Graft material</term><term>Graft particles</term><term>Grafted sites</term><term>Granule</term><term>Histologic</term><term>Histologic sections</term><term>Histomorphometric study</term><term>Hyaluronic</term><term>Hyaluronic acid</term><term>Hyaluronic acid carrier</term><term>Impl</term><term>Implant</term><term>Implant placement</term><term>Implants research</term><term>International journal</term><term>Local anesthesia</term><term>Maxillary</term><term>Maxillary sinus</term><term>Maxillofacial surgery</term><term>Mineralized bone graft substitute</term><term>Morphometric analysis</term><term>Musculoskeletal transplant foundation</term><term>Oral impl</term><term>Oral maxillofacial implants</term><term>Osteogenic properties</term><term>Other materials</term><term>Passive closure</term><term>Phosphate granules</term><term>Preoperative ridge height</term><term>Residual graft material</term><term>Restorative dentistry</term><term>Results show</term><term>Ridge height</term><term>Ridge heights</term><term>Similar extent</term><term>Sinus</term><term>Sinus elevation</term><term>Small amount</term><term>Support bone formation</term><term>Surgical site</term><term>Tissue dimensions</term><term>Torque values</term><term>Treatment group</term><term>Treatment groups</term><term>Valentini abensur</term><term>Welcome addition</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract">Objectives: Natural and synthetic graft materials are used routinely in sinus floor augmentations to help support implants in atrophic maxillary ridges. This clinical study was based on the hypothesis that the clinical effectiveness of demineralized freeze‐dried bone allograft/demineralized bone matrix (DFDBA/DBM) in sinus lifts varies when used in combination bone graft substitute materials. To test this hypothesis, DFDBA was used together with one of three materials: in saline plus anorganic bone (DFDBA: Bio‐Oss®); in hyaluronic acid (DFDBA: HY, 32 : 68, w/w; DBX®) alone; DBX® plus Bio‐Oss®; and DBX® plus tricalcium phosphate granules (β‐TCP).</div></front></TEI><istex><corpusName>wiley</corpusName><keywords><teeft><json:string>dfdba</json:string><json:string>sinus</json:string><json:string>augmentation</json:string><json:string>graft</json:string><json:string>demineralized</json:string><json:string>implant</json:string><json:string>allograft</json:string><json:string>hyaluronic</json:string><json:string>histologic</json:string><json:string>granule</json:string><json:string>maxillary</json:string><json:string>clin</json:string><json:string>impl</json:string><json:string>graft material</json:string><json:string>oral impl</json:string><json:string>autogenous</json:string><json:string>hyaluronic acid</json:string><json:string>demineralized bone allograft</json:string><json:string>bone formation</json:string><json:string>international journal</json:string><json:string>histologic sections</json:string><json:string>valentini abensur</json:string><json:string>bone graft substitute</json:string><json:string>autogenous bone</json:string><json:string>maxillary sinus</json:string><json:string>implant placement</json:string><json:string>hyaluronic acid carrier</json:string><json:string>treatment group</json:string><json:string>treatment groups</json:string><json:string>ridge heights</json:string><json:string>ridge height</json:string><json:string>closure</json:string><json:string>buccal window</json:string><json:string>phosphate granules</json:string><json:string>bone allograft</json:string><json:string>bone graft substitutes</json:string><json:string>passive closure</json:string><json:string>local anesthesia</json:string><json:string>residual graft material</json:string><json:string>histomorphometric study</json:string><json:string>elevation</json:string><json:string>biopsy</json:string><json:string>sinus elevation</json:string><json:string>alveolar height</json:string><json:string>consent forms</json:string><json:string>bone graft materials</json:string><json:string>musculoskeletal transplant foundation</json:string><json:string>deproteinized cancellous</json:string><json:string>grafted sites</json:string><json:string>morphometric analysis</json:string><json:string>other materials</json:string><json:string>complete wound closure</json:string><json:string>dental medicine</json:string><json:string>clinical study</json:string><json:string>augmentation procedure</json:string><json:string>collagen membrane</json:string><json:string>support bone formation</json:string><json:string>surgical site</json:string><json:string>tissue dimensions</json:string><json:string>preoperative ridge height</json:string><json:string>torque values</json:string><json:string>bone volume</json:string><json:string>similar extent</json:string><json:string>mineralized bone graft substitute</json:string><json:string>clinical effectiveness</json:string><json:string>small amount</json:string><json:string>bone graft material</json:string><json:string>considerable variation</json:string><json:string>graft particles</json:string><json:string>cortical bone</json:string><json:string>dfdba particles</json:string><json:string>considerable bone marrow</json:string><json:string>results show</json:string><json:string>osteogenic properties</json:string><json:string>absolute amount</json:string><json:string>welcome addition</json:string><json:string>clinical evaluation</json:string><json:string>restorative dentistry</json:string><json:string>alveolar ridge height</json:string><json:string>maxillofacial surgery</json:string><json:string>oral maxillofacial implants</json:string><json:string>implants research</json:string></teeft></keywords><author><json:item><name>Zvi Schwartz</name><affiliations><json:string>Faculty of Dental Medicine, Hebrew University Hadassah, Jerusalem, Israel</json:string></affiliations></json:item><json:item><name>Moshe Goldstein</name><affiliations><json:string>Faculty of Dental Medicine, Hebrew University Hadassah, Jerusalem, Israel</json:string></affiliations></json:item><json:item><name>Einav Raviv</name><affiliations><json:string>Faculty of Dental Medicine, Hebrew University Hadassah, Jerusalem, Israel</json:string></affiliations></json:item><json:item><name>Ariel Hirsch</name><affiliations><json:string>Faculty of Dental Medicine, Hebrew University Hadassah, Jerusalem, Israel</json:string></affiliations></json:item><json:item><name>Don M. Ranly</name><affiliations><json:string>Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA</json:string></affiliations></json:item><json:item><name>Barbara D. Boyan</name><affiliations><json:string>Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>augmentation</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>β‐TCP</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Bio‐Oss®</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>DBM</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>DBX®</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>DFDBA</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>histology</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>human</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>sinus lift</value></json:item></subject><articleId><json:string>CLR1303</json:string></articleId><arkIstex>ark:/67375/WNG-11C2XVKL-C</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><abstract>Objectives: Natural and synthetic graft materials are used routinely in sinus floor augmentations to help support implants in atrophic maxillary ridges. This clinical study was based on the hypothesis that the clinical effectiveness of demineralized freeze‐dried bone allograft/demineralized bone matrix (DFDBA/DBM) in sinus lifts varies when used in combination bone graft substitute materials. To test this hypothesis, DFDBA was used together with one of three materials: in saline plus anorganic bone (DFDBA: Bio‐Oss®); in hyaluronic acid (DFDBA: HY, 32 : 68, w/w; DBX®) alone; DBX® plus Bio‐Oss®; and DBX® plus tricalcium phosphate granules (β‐TCP).</abstract><qualityIndicators><score>7.459</score><pdfWordCount>4355</pdfWordCount><pdfCharCount>27270</pdfCharCount><pdfVersion>1.3</pdfVersion><pdfPageCount>8</pdfPageCount><pdfPageSize>595.276 x 782.362 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractWordCount>92</abstractWordCount><abstractCharCount>653</abstractCharCount><keywordCount>9</keywordCount></qualityIndicators><title>Clinical evaluation of demineralized bone allograft in a hyaluronic acid carrier for sinus lift augmentation in humans: a computed tomography and histomorphometric study</title><pmid><json:string>17348885</json:string></pmid><genre><json:string>article</json:string></genre><host><title>Clinical Oral Implants Research</title><language><json:string>unknown</json:string></language><doi><json:string>10.1111/(ISSN)1600-0501</json:string></doi><issn><json:string>0905-7161</json:string></issn><eissn><json:string>1600-0501</json:string></eissn><publisherId><json:string>CLR</json:string></publisherId><volume>18</volume><issue>2</issue><pages><first>204</first><last>211</last><total>8</total></pages><genre><json:string>journal</json:string></genre></host><namedEntities><unitex><date><json:string>2007</json:string></date><geogName></geogName><orgName><json:string>Geistlich Sons Ltd</json:string><json:string>Ministry of Health</json:string><json:string>Ethics Committee of Hadassah Hebrew University</json:string><json:string>Israel Zvi Schwartz, Don M</json:string><json:string>MTF</json:string><json:string>Musculoskeletal Transplant Foundation</json:string><json:string>Research Triangle Park, NC, USA</json:string><json:string>Department of Periodontics, Hebrew University Hadassah Faculty of Dental Medicine</json:string><json:string>Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA Clinical</json:string></orgName><orgName_funder></orgName_funder><orgName_provider></orgName_provider><persName><json:string>Barbara D. Boyan</json:string><json:string>Boyan Authors</json:string><json:string>Moshe Goldstein</json:string><json:string>Silver Springs</json:string><json:string>Ariel Hirsch</json:string><json:string>Dr Perry</json:string></persName><placeName><json:string>Switzerland</json:string><json:string>New Trabecular</json:string><json:string>Israel</json:string></placeName><ref_url></ref_url><ref_bibl><json:string>Cammack et al. 2005</json:string><json:string>Turunen et al. 2004</json:string><json:string>Weindl et al. 2004</json:string><json:string>Kalk et al. 1996</json:string><json:string>Groeneveld et al. 1999</json:string><json:string>Zijderveld et al. 2005</json:string><json:string>Tadjoedin et al. 2003</json:string><json:string>Lundgren et al. 1996</json:string><json:string>van den Bergh et al. 1998</json:string><json:string>Libin et al. 1975</json:string><json:string>Fukuda 2004</json:string><json:string>Schwartz et al. 1998</json:string><json:string>Schwartz et al</json:string><json:string>Hallman et al. 2005</json:string><json:string>Valentini & Abensur 1997</json:string></ref_bibl><bibl></bibl></unitex></namedEntities><ark><json:string>ark:/67375/WNG-11C2XVKL-C</json:string></ark><categories><wos><json:string>1 - science</json:string><json:string>2 - engineering, biomedical</json:string><json:string>2 - dentistry, oral surgery & medicine</json:string></wos><scienceMetrix><json:string>1 - health sciences</json:string><json:string>2 - clinical medicine</json:string><json:string>3 - dentistry</json:string></scienceMetrix><scopus><json:string>1 - Health Sciences</json:string><json:string>2 - Dentistry</json:string><json:string>3 - Oral Surgery</json:string></scopus></categories><publicationDate>2007</publicationDate><copyrightDate>2007</copyrightDate><doi><json:string>10.1111/j.1600-0501.2006.01303.x</json:string></doi><id>FF9692D9FDA0790A697788B46C8279C31BF4D789</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/FF9692D9FDA0790A697788B46C8279C31BF4D789/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/FF9692D9FDA0790A697788B46C8279C31BF4D789/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/FF9692D9FDA0790A697788B46C8279C31BF4D789/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main">Clinical evaluation of demineralized bone allograft in a hyaluronic acid carrier for sinus lift augmentation in humans: a computed tomography and histomorphometric study</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2007-04"></date></publicationStmt><notesStmt><note type="content-type" subtype="article" source="article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</note><note type="publication-type" subtype="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="article"><analytic><title level="a" type="main">Clinical evaluation of demineralized bone allograft in a hyaluronic acid carrier for sinus lift augmentation in humans: a computed tomography and histomorphometric study</title><title level="a" type="short">DBX® for sinus lift augmentation</title><author xml:id="author-0000"><persName><forename type="first">Zvi</forename><surname>Schwartz</surname></persName><affiliation>Faculty of Dental Medicine, Hebrew University Hadassah, Jerusalem, Israel<address><country key="IL"></country></address></affiliation></author><author xml:id="author-0001"><persName><forename type="first">Moshe</forename><surname>Goldstein</surname></persName><affiliation>Faculty of Dental Medicine, Hebrew University Hadassah, Jerusalem, Israel<address><country key="IL"></country></address></affiliation></author><author xml:id="author-0002"><persName><forename type="first">Einav</forename><surname>Raviv</surname></persName><affiliation>Faculty of Dental Medicine, Hebrew University Hadassah, Jerusalem, Israel<address><country key="IL"></country></address></affiliation></author><author xml:id="author-0003"><persName><forename type="first">Ariel</forename><surname>Hirsch</surname></persName><affiliation>Faculty of Dental Medicine, Hebrew University Hadassah, Jerusalem, Israel<address><country key="IL"></country></address></affiliation></author><author xml:id="author-0004"><persName><forename type="first">Don M.</forename><surname>Ranly</surname></persName><affiliation>Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA<address><country key="US"></country></address></affiliation></author><author xml:id="author-0005"><persName><forename type="first">Barbara D.</forename><surname>Boyan</surname></persName><affiliation>Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA<address><country key="US"></country></address></affiliation></author><idno type="istex">FF9692D9FDA0790A697788B46C8279C31BF4D789</idno><idno type="ark">ark:/67375/WNG-11C2XVKL-C</idno><idno type="DOI">10.1111/j.1600-0501.2006.01303.x</idno><idno type="unit">CLR1303</idno><idno type="supplier">1303</idno><idno type="toTypesetVersion">file:CLR.CLR1303.pdf</idno></analytic><monogr><title level="j" type="main">Clinical Oral Implants Research</title><title level="j" type="alt">CLINICAL ORAL IMPLANTS RESEARCH</title><idno type="pISSN">0905-7161</idno><idno type="eISSN">1600-0501</idno><idno type="book-DOI">10.1111/(ISSN)1600-0501</idno><idno type="book-part-DOI">10.1111/clr.2007.18.issue-2</idno><idno type="product">CLR</idno><idno type="publisherDivision">ST</idno><imprint><biblScope unit="vol">18</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="204">204</biblScope><biblScope unit="page" to="211">211</biblScope><biblScope unit="page-count">8</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2007-04"></date></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><abstract xml:lang="en" style="main"><head>Abstract</head><p><hi rend="bold">Objectives: </hi> Natural and synthetic graft materials are used routinely in sinus floor augmentations to help support implants in atrophic maxillary ridges. This clinical study was based on the hypothesis that the clinical effectiveness of demineralized freeze‐dried bone allograft/demineralized bone matrix (DFDBA/DBM) in sinus lifts varies when used in combination bone graft substitute materials. To test this hypothesis, DFDBA was used together with one of three materials: in saline plus anorganic bone (DFDBA: Bio‐Oss<hi rend="superscript">®</hi>); in hyaluronic acid (DFDBA: HY, 32 : 68, w/w; DBX<hi rend="superscript">®</hi>) alone; DBX<hi rend="superscript">®</hi> plus Bio‐Oss<hi rend="superscript">®</hi>; and DBX<hi rend="superscript">®</hi> plus tricalcium phosphate granules (β‐TCP).</p><p><hi rend="bold">Material and methods: </hi> Thirty‐two sinus lift procedures, eight per group, were performed on 26 patients. Before surgery and at 8 months post‐surgery when implants were placed, ridge heights were visualized by computed tomography (CT) and measured by morphometric analysis. Cores of bone were removed by trephine at the sites of implant placement; these biopsies from the graft sites were used for histomorphometric analysis.</p><p><hi rend="bold">Results: </hi> All 32 sinus lift elevations were successful when measured by CT, increasing from an average 2.84±0.2 mm before treatment to 15.2±0.6 mm after treatment. The percent of each biopsy that was occupied by new bone and incorporated bone graft materials varied with each treatment: DFDBA+Bio‐Oss<hi rend="superscript">®</hi>, DBX<hi rend="superscript">®</hi>+Bio‐Oss<hi rend="superscript">®</hi>, or DBX<hi rend="superscript">®</hi> alone was higher than that for DBX<hi rend="superscript">®</hi>+β‐TCP by approximately 10%. When comparing only newly formed bone, DBX<hi rend="superscript">®</hi>+β‐TCP treatment resulted in 50% less bone than the other three preparations. All grafted sites received implants as per the treatment plan for each patient.</p><p><hi rend="bold">Conclusions: </hi> This study confirmed the hypothesis that new bone formation is dependent on the DFDBA formulation used and demonstrated that DBX<hi rend="superscript">®</hi>, alone or in combination with other materials, can be used successfully for sinus floor elevation.</p></abstract><textClass><keywords xml:lang="en"><term xml:id="k1">augmentation</term><term xml:id="k2">β‐TCP</term><term xml:id="k3">Bio‐Oss<hi rend="superscript">®</hi></term><term xml:id="k4">DBM</term><term xml:id="k5">DBX<hi rend="superscript">®</hi></term><term xml:id="k6">DFDBA</term><term xml:id="k7">histology</term><term xml:id="k8">human</term><term xml:id="k9">sinus lift</term></keywords><keywords rend="tocHeading1"><term>Original articles</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/FF9692D9FDA0790A697788B46C8279C31BF4D789/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Blackwell Publishing Ltd</publisherName><publisherLoc>Oxford, UK</publisherLoc></publisherInfo><doi origin="wiley" registered="yes">10.1111/(ISSN)1600-0501</doi><issn type="print">0905-7161</issn><issn type="electronic">1600-0501</issn><idGroup><id type="product" value="CLR"></id><id type="publisherDivision" value="ST"></id></idGroup><titleGroup><title type="main" sort="CLINICAL ORAL IMPLANTS RESEARCH">Clinical Oral Implants Research</title></titleGroup></publicationMeta><publicationMeta level="part" position="04002"><doi origin="wiley">10.1111/clr.2007.18.issue-2</doi><numberingGroup><numbering type="journalVolume" number="18">18</numbering><numbering type="journalIssue" number="2">2</numbering></numberingGroup><coverDate startDate="2007-04">April 2007</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="8" status="forIssue"><doi origin="wiley">10.1111/j.1600-0501.2006.01303.x</doi><idGroup><id type="unit" value="CLR1303"></id><id type="supplier" value="1303"></id></idGroup><countGroup><count type="pageTotal" number="8"></count></countGroup><titleGroup><title type="tocHeading1">Original articles</title></titleGroup><eventGroup><event type="firstOnline" date="2006-12-20"></event><event type="publishedOnlineFinalForm" date="2006-12-20"></event><event type="xmlConverted" agent="Converter:BPG_TO_WML3G version:2.3.2 mode:FullText source:FullText result:FullText" date="2010-03-15"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:4.0.1" date="2014-03-12"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-17"></event></eventGroup><numberingGroup><numbering type="pageFirst" number="204">204</numbering><numbering type="pageLast" number="211">211</numbering></numberingGroup><correspondenceTo><b>Correspondence to:</b>
<i>Zvi Schwartz</i>
Department of Periodontology
Hebrew University Hadassah
PO Box 12272
Jerusalem 91120
Israel
Tel.: +972 2 6777826/7
Fax: +972 2 6438705
e‐mail: <email normalForm="zvis1@cc.huji.ac.il">zvis1@cc.huji.ac.il</email></correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:CLR.CLR1303.pdf"></link></linkGroup></publicationMeta><contentMeta><unparsedEditorialHistory><b>Date:</b> Accepted 13 March 2006</unparsedEditorialHistory><countGroup><count type="figureTotal" number="8"></count><count type="tableTotal" number="1"></count><count type="formulaTotal" number="0"></count><count type="referenceTotal" number="16"></count><count type="wordTotal" number="5068"></count><count type="linksCrossRef" number="50"></count></countGroup><titleGroup><title type="main">Clinical evaluation of demineralized bone allograft in a hyaluronic acid carrier for sinus lift augmentation in humans: a computed tomography and histomorphometric study</title><title type="shortAuthors">Schwartz et al.</title><title type="short">DBX<sup>®</sup> for sinus lift augmentation</title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#a1"><personName><givenNames>Zvi</givenNames><familyName>Schwartz</familyName></personName></creator><creator creatorRole="author" xml:id="cr2" affiliationRef="#a1"><personName><givenNames>Moshe</givenNames><familyName>Goldstein</familyName></personName></creator><creator creatorRole="author" xml:id="cr3" affiliationRef="#a1"><personName><givenNames>Einav</givenNames><familyName>Raviv</familyName></personName></creator><creator creatorRole="author" xml:id="cr4" affiliationRef="#a1"><personName><givenNames>Ariel</givenNames><familyName>Hirsch</familyName></personName></creator><creator creatorRole="author" xml:id="cr5" affiliationRef="#a2"><personName><givenNames>Don M.</givenNames><familyName>Ranly</familyName></personName></creator><creator creatorRole="author" xml:id="cr6" affiliationRef="#a2"><personName><givenNames>Barbara D.</givenNames><familyName>Boyan</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="a1" countryCode="IL"><unparsedAffiliation>Faculty of Dental Medicine, Hebrew University Hadassah, Jerusalem, Israel</unparsedAffiliation></affiliation><affiliation xml:id="a2" countryCode="US"><unparsedAffiliation>Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en"><keyword xml:id="k1">augmentation</keyword><keyword xml:id="k2">β‐TCP</keyword><keyword xml:id="k3">Bio‐Oss<sup>®</sup></keyword><keyword xml:id="k4">DBM</keyword><keyword xml:id="k5">DBX<sup>®</sup></keyword><keyword xml:id="k6">DFDBA</keyword><keyword xml:id="k7">histology</keyword><keyword xml:id="k8">human</keyword><keyword xml:id="k9">sinus lift</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p><b>Objectives: </b> Natural and synthetic graft materials are used routinely in sinus floor augmentations to help support implants in atrophic maxillary ridges. This clinical study was based on the hypothesis that the clinical effectiveness of demineralized freeze‐dried bone allograft/demineralized bone matrix (DFDBA/DBM) in sinus lifts varies when used in combination bone graft substitute materials. To test this hypothesis, DFDBA was used together with one of three materials: in saline plus anorganic bone (DFDBA: Bio‐Oss<sup>®</sup>); in hyaluronic acid (DFDBA: HY, 32 : 68, w/w; DBX<sup>®</sup>) alone; DBX<sup>®</sup> plus Bio‐Oss<sup>®</sup>; and DBX<sup>®</sup> plus tricalcium phosphate granules (β‐TCP).</p><p><b>Material and methods: </b> Thirty‐two sinus lift procedures, eight per group, were performed on 26 patients. Before surgery and at 8 months post‐surgery when implants were placed, ridge heights were visualized by computed tomography (CT) and measured by morphometric analysis. Cores of bone were removed by trephine at the sites of implant placement; these biopsies from the graft sites were used for histomorphometric analysis.</p><p><b>Results: </b> All 32 sinus lift elevations were successful when measured by CT, increasing from an average 2.84±0.2 mm before treatment to 15.2±0.6 mm after treatment. The percent of each biopsy that was occupied by new bone and incorporated bone graft materials varied with each treatment: DFDBA+Bio‐Oss<sup>®</sup>, DBX<sup>®</sup>+Bio‐Oss<sup>®</sup>, or DBX<sup>®</sup> alone was higher than that for DBX<sup>®</sup>+β‐TCP by approximately 10%. When comparing only newly formed bone, DBX<sup>®</sup>+β‐TCP treatment resulted in 50% less bone than the other three preparations. All grafted sites received implants as per the treatment plan for each patient.</p><p><b>Conclusions: </b> This study confirmed the hypothesis that new bone formation is dependent on the DFDBA formulation used and demonstrated that DBX<sup>®</sup>, alone or in combination with other materials, can be used successfully for sinus floor elevation.</p><!--
To cite this article:
Schwartz Z, Goldstein M, Raviv E, Hirsch A, Ranly DM, Boyan BD. Clinical evaluation of demineralized bone allograft in a hyaluronic acid carrier for sinus lift augmentation in humans: a computed tomography and histomorphometric study.
Clin. Oral Impl. Res.
doi: 10.1111/j.1600-0501.2006.01303.x
--></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Clinical evaluation of demineralized bone allograft in a hyaluronic acid carrier for sinus lift augmentation in humans: a computed tomography and histomorphometric study</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>DBX® for sinus lift augmentation</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Clinical evaluation of demineralized bone allograft in a hyaluronic acid carrier for sinus lift augmentation in humans: a computed tomography and histomorphometric study</title></titleInfo><name type="personal"><namePart type="given">Zvi</namePart><namePart type="family">Schwartz</namePart><affiliation>Faculty of Dental Medicine, Hebrew University Hadassah, Jerusalem, Israel</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Moshe</namePart><namePart type="family">Goldstein</namePart><affiliation>Faculty of Dental Medicine, Hebrew University Hadassah, Jerusalem, Israel</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Einav</namePart><namePart type="family">Raviv</namePart><affiliation>Faculty of Dental Medicine, Hebrew University Hadassah, Jerusalem, Israel</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Ariel</namePart><namePart type="family">Hirsch</namePart><affiliation>Faculty of Dental Medicine, Hebrew University Hadassah, Jerusalem, Israel</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Don M.</namePart><namePart type="family">Ranly</namePart><affiliation>Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Barbara D.</namePart><namePart type="family">Boyan</namePart><affiliation>Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">2007-04</dateIssued><edition>Date: Accepted 13 March 2006</edition><copyrightDate encoding="w3cdtf">2007</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><extent unit="figures">8</extent><extent unit="tables">1</extent><extent unit="formulas">0</extent><extent unit="references">16</extent><extent unit="linksCrossRef">50</extent><extent unit="words">5068</extent></physicalDescription><abstract>Objectives: Natural and synthetic graft materials are used routinely in sinus floor augmentations to help support implants in atrophic maxillary ridges. This clinical study was based on the hypothesis that the clinical effectiveness of demineralized freeze‐dried bone allograft/demineralized bone matrix (DFDBA/DBM) in sinus lifts varies when used in combination bone graft substitute materials. To test this hypothesis, DFDBA was used together with one of three materials: in saline plus anorganic bone (DFDBA: Bio‐Oss®); in hyaluronic acid (DFDBA: HY, 32 : 68, w/w; DBX®) alone; DBX® plus Bio‐Oss®; and DBX® plus tricalcium phosphate granules (β‐TCP).</abstract><abstract>Material and methods: Thirty‐two sinus lift procedures, eight per group, were performed on 26 patients. Before surgery and at 8 months post‐surgery when implants were placed, ridge heights were visualized by computed tomography (CT) and measured by morphometric analysis. Cores of bone were removed by trephine at the sites of implant placement; these biopsies from the graft sites were used for histomorphometric analysis.</abstract><abstract>Results: All 32 sinus lift elevations were successful when measured by CT, increasing from an average 2.84±0.2 mm before treatment to 15.2±0.6 mm after treatment. The percent of each biopsy that was occupied by new bone and incorporated bone graft materials varied with each treatment: DFDBA+Bio‐Oss®, DBX®+Bio‐Oss®, or DBX® alone was higher than that for DBX®+β‐TCP by approximately 10%. When comparing only newly formed bone, DBX®+β‐TCP treatment resulted in 50% less bone than the other three preparations. All grafted sites received implants as per the treatment plan for each patient.</abstract><abstract>Conclusions: This study confirmed the hypothesis that new bone formation is dependent on the DFDBA formulation used and demonstrated that DBX®, alone or in combination with other materials, can be used successfully for sinus floor elevation.</abstract><subject lang="en"><genre>keywords</genre><topic>augmentation</topic><topic>β‐TCP</topic><topic>Bio‐Oss®</topic><topic>DBM</topic><topic>DBX®</topic><topic>DFDBA</topic><topic>histology</topic><topic>human</topic><topic>sinus lift</topic></subject><relatedItem type="host"><titleInfo><title>Clinical Oral Implants Research</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><identifier type="ISSN">0905-7161</identifier><identifier type="eISSN">1600-0501</identifier><identifier type="DOI">10.1111/(ISSN)1600-0501</identifier><identifier type="PublisherID">CLR</identifier><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>18</number></detail><detail type="issue"><caption>no.</caption><number>2</number></detail><extent unit="pages"><start>204</start><end>211</end><total>8</total></extent></part></relatedItem><identifier type="istex">FF9692D9FDA0790A697788B46C8279C31BF4D789</identifier><identifier type="ark">ark:/67375/WNG-11C2XVKL-C</identifier><identifier type="DOI">10.1111/j.1600-0501.2006.01303.x</identifier><identifier type="ArticleID">CLR1303</identifier><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-L0C46X92-X">wiley</recordContentSource><recordOrigin>Blackwell Publishing Ltd</recordOrigin></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/document/FF9692D9FDA0790A697788B46C8279C31BF4D789/metadata/json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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