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Randomized Controlled Trial to Compare Two Bone Substitutes in the Treatment of Bony Dehiscences

Identifieur interne : 006618 ( Istex/Corpus ); précédent : 006617; suivant : 006619

Randomized Controlled Trial to Compare Two Bone Substitutes in the Treatment of Bony Dehiscences

Auteurs : Nele Van Assche ; Sofie Michels ; Ignace Naert ; Marc Quirynen

Source :

RBID : ISTEX:CD6EEDCFE2CDC88E363FF767F47C2B2A3A35C4E0

English descriptors

Abstract

Aim: This in vivo split‐mouth randomized controlled trial compared a synthetic bone substitute with a bovine bone mineral to cover bone dehiscences after implant insertion.

Url:
DOI: 10.1111/j.1708-8208.2011.00408.x

Links to Exploration step

ISTEX:CD6EEDCFE2CDC88E363FF767F47C2B2A3A35C4E0

Le document en format XML

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This in vivo split‐mouth randomized controlled trial compared a synthetic bone substitute with a bovine bone mineral to cover bone dehiscences after implant insertion.</p>
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<hi rend="bold">Materials and Methods:</hi>
Fourteen patients received four to six implants to support an overdenture. Two comparable dehiscences within the same patient were first covered with a layer of autogenous bone, followed by a layer of either Bio‐Oss® (group 1; Geistlich Pharma AG, Wolhusen, Switzerland) or Straumann BoneCeramic® (group 2; Institut Straumann AG, Basel, Switzerland) and sealed by a resorbable membrane. The change in vertical dimension of the defect was measured at implant placement and at abutment connection (6.5 months). Clinical and radiological parameters were evaluated up to 1 year of loading.</p>
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<hi rend="bold">Results:</hi>
The vertical size of the defect at surgery was 6.4 ± 1.6 mm for group 1 and 6.4 ± 2.2 mm for group 2 sites, measured from the implant shoulder. After 6.5 months, the depth of the defect was reduced to 1.5 ± 1.2 mm and 1.9 ± 1.2 mm for group 1 and group 2 sites, respectively (
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 > 0.05). No implants failed during follow‐up. Mean marginal bone loss over the SLActive surface was 0.94 mm (group 1), 0.81 mm (group 2), and 0.93 mm (group 3, no dehiscence) after 1 year of loading.</p>
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Both bone substitutes behaved equally effectively.</p>
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Fourteen patients received four to six implants to support an overdenture. Two comparable dehiscences within the same patient were first covered with a layer of autogenous bone, followed by a layer of either Bio‐Oss® (group 1; Geistlich Pharma AG, Wolhusen, Switzerland) or Straumann BoneCeramic® (group 2; Institut Straumann AG, Basel, Switzerland) and sealed by a resorbable membrane. The change in vertical dimension of the defect was measured at implant placement and at abutment connection (6.5 months). Clinical and radiological parameters were evaluated up to 1 year of loading.</p>
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The vertical size of the defect at surgery was 6.4 ± 1.6 mm for group 1 and 6.4 ± 2.2 mm for group 2 sites, measured from the implant shoulder. After 6.5 months, the depth of the defect was reduced to 1.5 ± 1.2 mm and 1.9 ± 1.2 mm for group 1 and group 2 sites, respectively (
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